| Probe |
Symbol |
Description |
Chromosome |
Chromosome Location |
GenBank |
Gene |
PubMed |
Gene Ontology |
Pathway |
| TC1200000203.mm.2 |
Rrm2 |
ribonucleotide reductase M2 |
12 |
24708253 |
NM_009104, BC085136 NM_009104, BC085136 |
20135 |
72 |
blastocyst development ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding nuclear envelope cytoplasm cytosol cytosol cytosol ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex DNA replication ferric iron binding deoxyribonucleotide metabolic process deoxyribonucleotide biosynthetic process deoxyribonucleotide biosynthetic process oxidoreductase activity identical protein binding protein homodimerization activity metal ion binding protein heterotetramerization |
00230 00240 00480 01100 04115 |
| TC0800001737.mm.2 |
Gas6 |
growth arrest specific 6 |
8 |
-13465373 |
NM_019521, BC005444 NM_019521, BC005444 |
14456 |
109 |
neuron migration phosphatidylserine binding positive regulation of protein phosphorylation positive regulation of cytokine-mediated signaling pathway positive regulation of glomerular filtration signaling receptor binding calcium ion binding extracellular region extracellular space extracellular space extracellular space cytoplasm protein phosphorylation phagocytosis signal transduction enzyme linked receptor protein signaling pathway blood coagulation cellular response to starvation positive regulation of gene expression negative regulation of tumor necrosis factor-mediated signaling pathway macrophage cytokine production peptidyl-serine phosphorylation fusion of virus membrane with host plasma membrane viral genome replication protein tyrosine kinase activator activity protein-macromolecule adaptor activity receptor tyrosine kinase binding cell-substrate adhesion positive regulation of TOR signaling activation of protein kinase B activity negative regulation of interferon-gamma production negative regulation of interleukin-1 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of natural killer cell differentiation positive regulation of peptidyl-serine phosphorylation cellular response to interferon-alpha cellular response to drug B cell chemotaxis regulation of growth cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process apoptotic cell clearance apoptotic cell clearance negative regulation of DNA-binding transcription factor activity protein kinase B signaling protein kinase B signaling protein kinase B signaling protein kinase B signaling positive regulation of protein kinase activity negative regulation of transcription, DNA-templated viral entry into host cell receptor-mediated virion attachment to host cell positive regulation of protein export from nucleus metal ion binding receptor ligand activity receptor ligand activity receptor ligand activity positive regulation of fibroblast proliferation positive regulation of phagocytosis positive regulation of protein kinase B signaling positive regulation of protein tyrosine kinase activity negative regulation of biomineral tissue development positive regulation of ERK1 and ERK2 cascade calcium ion transmembrane transport cellular response to vitamin K cellular response to glucose stimulus cellular response to growth factor stimulus cellular response to growth factor stimulus protein localization to plasma membrane hematopoietic stem cell migration to bone marrow negative regulation of oligodendrocyte apoptotic process negative regulation of fibroblast apoptotic process negative regulation of endothelial cell apoptotic process positive regulation of dendritic cell chemotaxis negative regulation of dendritic cell apoptotic process |
|
| TC1500002217.mm.2 |
Racgap1 |
Rac GTPase-activating protein 1 |
15 |
-99620495 |
NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715 NM_001253808, NM_001253809, NM_012025, BC010715 |
26934 |
52 |
mitotic cytokinesis actomyosin contractile ring assembly GTPase activator activity phosphatidylinositol-3,4,5-trisphosphate binding nucleus nucleoplasm cytoplasm spindle cytoskeleton plasma membrane ion transport cell cycle signal transduction multicellular organism development spermatogenesis neuroblast proliferation microtubule binding sulfate transport lipid binding membrane protein kinase binding cell differentiation midbody extrinsic component of cytoplasmic side of plasma membrane cytoplasmic vesicle cleavage furrow positive regulation of cytokinesis intracellular signal transduction alpha-tubulin binding gamma-tubulin binding regulation of embryonic development metal ion binding beta-tubulin binding spindle midzone mitotic spindle midzone assembly cell division regulation of attachment of spindle microtubules to kinetochore mitotic spindle centralspindlin complex |
|
| TC0100000298.mm.2 |
Il1rl1 |
interleukin 1 receptor-like 1 |
1 |
40439628, 40439628, 40429569 |
NM_001025602, NM_010743, BC051445 NM_001025602, NM_010743, BC051445 NM_001025602, NM_010743, BC051445 |
17082 |
293 |
interleukin-33 binding interleukin-33 binding interleukin-33 receptor activity interleukin-33 receptor activity negative regulation of T-helper 1 type immune response interleukin-1 receptor activity protein binding extracellular region extracellular space cytosol plasma membrane focal adhesion signal transduction negative regulation of cell population proliferation external side of plasma membrane external side of plasma membrane cell surface membrane integral component of membrane hydrolase activity extracellular matrix negative regulation of interferon-gamma production positive regulation of chemokine production positive regulation of interleukin-5 production positive regulation of macrophage activation negative regulation of I-kappaB kinase/NF-kappaB signaling NAD(P)+ nucleosidase activity positive regulation of inflammatory response NAD+ nucleotidase, cyclic ADP-ribose generating |
|
| TC0400001934.mm.2 |
Srm |
spermidine synthase |
4 |
148591512 |
NM_009272, BC005566 NM_009272, BC005566 |
20810 |
24 |
catalytic activity spermidine synthase activity spermidine synthase activity polyamine metabolic process polyamine biosynthetic process spermidine biosynthetic process spermidine biosynthetic process transferase activity identical protein binding protein homodimerization activity cellular response to leukemia inhibitory factor |
00270 00330 00410 00480 01100 |
| TC1000000372.mm.2 |
Sesn1 |
sestrin 1 |
10 |
41810573, 41887438 |
NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403 NM_001013370, NM_001162908, BC055753, BC100403 |
140742 |
33 |
fibrillar center protein binding nucleus nucleoplasm cytoplasm cytoplasm positive regulation of macroautophagy oxidoreductase activity oxidoreductase activity, acting on peroxide as acceptor negative regulation of cell growth TORC2 complex cellular response to amino acid starvation cellular response to glucose starvation regulation of protein kinase B signaling GATOR2 complex GATOR2 complex leucine binding leucine binding cellular response to amino acid stimulus cellular response to leucine reactive oxygen species metabolic process cellular oxidant detoxification regulation of response to reactive oxygen species negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling cellular response to leucine starvation |
04115 |
| TC1100000168.mm.2 |
Cnrip1 |
cannabinoid receptor interacting protein 1 |
11 |
17051858 |
NM_029861, BC087946 NM_029861, BC087946 |
380686 |
27 |
cytoplasm plasma membrane plasma membrane protein C-terminus binding regulation of signaling receptor activity type 1 cannabinoid receptor binding type 1 cannabinoid receptor binding myelin sheath negative regulation of signaling receptor activity negative regulation of signaling receptor activity |
|
| TC1400002746.mm.2 |
Gpr183 |
G protein-coupled receptor 183 |
14 |
-121952330 |
NM_183031, BC052868 NM_183031, BC052868 |
321019 |
50 |
adaptive immune response B cell activation involved in immune response mature B cell differentiation involved in immune response immune system process dendritic cell chemotaxis G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane humoral immune response signal transduction G protein-coupled receptor signaling pathway oxysterol binding oxysterol binding T cell chemotaxis membrane integral component of membrane osteoclast differentiation leukocyte chemotaxis leukocyte chemotaxis positive regulation of B cell proliferation positive regulation of B cell proliferation dendritic cell homeostasis cell chemotaxis T follicular helper cell differentiation positive regulation of ERK1 and ERK2 cascade regulation of astrocyte chemotaxis |
|
| TC1500000453.mm.2 |
Myc |
myelocytomatosis oncogene |
15 |
61985340 |
NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 NM_001177352, NM_001177353, NM_001177354, NM_010849, BC138931, BC138932 |
17869 |
1226 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II MAPK cascade re-entry into mitotic cell cycle chromatin euchromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding core promoter sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific branching involved in ureteric bud morphogenesis B cell apoptotic process positive regulation of mesenchymal cell proliferation regulation of oxidative phosphorylation positive regulation of B cell apoptotic process DNA binding DNA binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleolus cytoplasm spindle glucose metabolic process chromatin remodeling transcription, DNA-templated DNA-templated transcription, initiation regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription by RNA polymerase II pyruvate transport amino acid transport cellular iron ion homeostasis activation of cysteine-type endopeptidase activity involved in apoptotic process cellular response to DNA damage stimulus cellular response to DNA damage stimulus inner mitochondrial membrane organization cell cycle arrest regulation of mitotic cell cycle transcription factor binding cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage response to radiation response to radiation response to gamma radiation regulation of gene expression regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of mitochondrial membrane potential positive regulation of smooth muscle cell migration Wnt signaling pathway protein processing nuclear body transformation of host cell by virus axon ubiquitin protein ligase binding negative regulation of protein binding regulation of telomere maintenance protein-DNA complex disassembly protein-containing complex activating transcription factor binding cellular response to interferon-alpha cellular response to drug cellular response to drug skeletal muscle cell differentiation middle ear morphogenesis regulation of apoptotic process regulation of apoptotic process positive regulation of catalytic activity response to alkaloid positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of DNA binding pigmentation sequence-specific DNA binding canonical Wnt signaling pathway involved in negative regulation of apoptotic process canonical Wnt signaling pathway involved in positive regulation of apoptotic process protein-containing complex binding negative regulation of monocyte differentiation positive regulation of cell cycle positive regulation of glycolytic process positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of glucose import lactic acid secretion protein dimerization activity positive regulation of fibroblast proliferation negative regulation of fibroblast proliferation perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation skeletal system morphogenesis positive regulation of epithelial cell proliferation detection of mechanical stimulus involved in sensory perception of sound chromosome organization negative regulation of cell division positive regulation of telomerase activity positive regulation of glial cell proliferation positive regulation of transcription initiation from RNA polymerase II promoter negative regulation of cell death ERK1 and ERK2 cascade repressing transcription factor binding E-box binding cellular response to hypoxia positive regulation of metanephric cap mesenchymal cell proliferation positive regulation of cellular respiration positive regulation of oxidative phosphorylation regulation of somatic stem cell population maintenance positive regulation of DNA methylation positive regulation of DNA biosynthetic process positive regulation of response to DNA damage stimulus positive regulation of ATP biosynthetic process positive regulation of apoptotic signaling pathway positive regulation of apoptotic signaling pathway |
04010 04012 04110 04310 04350 04630 05200 05210 05213 05216 05219 05220 05221 05222 |
| TC0100001550.mm.2 |
Aldh9a1 |
aldehyde dehydrogenase 9, subfamily A1 |
1 |
167349990 |
NM_019993, BC003297 NM_019993, BC003297 |
56752 |
27 |
aldehyde dehydrogenase (NAD+) activity aldehyde dehydrogenase (NAD+) activity cytoplasm mitochondrion cytosol cytosol cellular aldehyde metabolic process carnitine metabolic process oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor aminobutyraldehyde dehydrogenase activity aminobutyraldehyde dehydrogenase activity neurotransmitter biosynthetic process identical protein binding amine binding 4-trimethylammoniobutyraldehyde dehydrogenase activity 4-trimethylammoniobutyraldehyde dehydrogenase activity NAD binding protein homotetramerization |
00010 00053 00071 00280 00310 00330 00340 00380 00410 00561 00620 00640 01100 |
| TC0900001182.mm.2 |
Slc9a9 |
solute carrier family 9 (sodium/hydrogen exchanger), member 9 |
9 |
94669891 |
NM_177909, BC099942, BC153825 NM_177909, BC099942, BC153825 NM_177909, BC099942, BC153825 |
331004 |
22 |
endosome plasma membrane ion transport cation transport sodium ion transport regulation of pH antiporter activity solute:proton antiporter activity sodium:proton antiporter activity potassium:proton antiporter activity membrane integral component of membrane regulation of intracellular pH recycling endosome recycling endosome transmembrane transport potassium ion transmembrane transport sodium ion import across plasma membrane |
|
| TC0500000298.mm.2 |
Cenpa |
centromere protein A |
5 |
30666885 |
NM_007681, BC011038 NM_007681, BC011038 |
12615 |
43 |
establishment of mitotic spindle orientation mitotic cytokinesis chromosome, centromeric region chromosome, centromeric region kinetochore condensed nuclear chromosome kinetochore condensed chromosome, centromeric region condensed chromosome, centromeric region nucleosome condensed chromosome inner kinetochore DNA binding nucleus nucleus nucleoplasm chromosome pericentric heterochromatin protein heterodimerization activity kinetochore assembly protein localization to chromosome, centromeric region |
|
| TC1300001814.mm.2 |
F13a1 |
coagulation factor XIII, A1 subunit |
13 |
-36867177, -36867177 |
NM_001166391, NM_028784, BC040274 NM_001166391, NM_028784, BC040274 NM_001166391, NM_028784, BC040274 |
74145 |
69 |
protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity extracellular region cytoplasm blood coagulation blood coagulation hemostasis transferase activity transferase activity, transferring acyl groups peptide cross-linking peptide cross-linking peptide cross-linking metal ion binding collagen-containing extracellular matrix blood coagulation, fibrin clot formation blood coagulation, fibrin clot formation blood coagulation, fibrin clot formation |
04610 |
| TC0400001639.mm.2 |
Stmn1 |
stathmin 1 |
4 |
134468319 |
NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396 NM_019641, BC010581, BC031831, BC054396 |
16765 |
112 |
mitotic cytokinesis mitotic cytokinesis protein binding cytoplasm cytoplasm cytosol cytoskeleton microtubule microtubule depolymerization microtubule depolymerization mitotic spindle organization multicellular organism development nervous system development axonogenesis tubulin binding tubulin binding membrane cell differentiation regulation of microtubule polymerization or depolymerization regulation of microtubule polymerization or depolymerization negative regulation of microtubule polymerization negative regulation of microtubule polymerization neuron projection development negative regulation of Rho protein signal transduction neuron projection hepatocyte growth factor receptor signaling pathway positive regulation of cellular component movement negative regulation of stress fiber assembly establishment of skin barrier negative regulation of thrombin-activated receptor signaling pathway negative regulation of guanyl-nucleotide exchange factor activity |
04010 |
| TC0100002285.mm.2 |
Slc40a1 |
solute carrier family 40 (iron-regulated transporter), member 1 |
1 |
-45908069 |
NM_016917, BC003438 NM_016917, BC003438 |
53945 |
138 |
lymphocyte homeostasis endothelium development iron ion transmembrane transporter activity iron ion transmembrane transporter activity iron ion transmembrane transporter activity protein binding nucleoplasm cytosol plasma membrane plasma membrane ion transport iron ion transport cellular iron ion homeostasis synaptic vesicle ferrous iron transmembrane transporter activity membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane peptide hormone binding peptide hormone binding peptide hormone binding regulation of transcription from RNA polymerase II promoter in response to iron iron ion transmembrane transport iron ion transmembrane transport iron ion transmembrane transport identical protein binding negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II spleen development iron ion homeostasis iron ion homeostasis spleen trabecula formation multicellular organismal iron ion homeostasis iron ion export across plasma membrane |
|
| TC1700001173.mm.2 |
Rasgrp3 |
RAS, guanyl releasing protein 3 |
17 |
75435904, 75465537 |
NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127 NM_001166493, NM_207246, BC066069, BC066127 |
240168 |
21 |
guanyl-nucleotide exchange factor activity GTPase activator activity cytoplasm Ras protein signal transduction kinase binding small GTPase binding small GTPase binding guanyl-nucleotide exchange factor complex regulation of GTPase activity perinuclear region of cytoplasm |
04010 04662 |
| TC0800001247.mm.2 |
Prmt7 |
protein arginine N-methyltransferase 7 |
8 |
106211053 |
NM_145404, BC006705, BC057177 NM_145404, BC006705, BC057177 NM_145404, BC006705, BC057177 |
214572 |
42 |
spliceosomal snRNP assembly fibrillar center protein binding nucleus nucleoplasm cytoplasm cytosol chromatin organization regulation of gene expression by genetic imprinting protein methylation methyltransferase activity histone-arginine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity [myelin basic protein]-arginine N-methyltransferase activity histone methylation transferase activity peptidyl-arginine methylation cell differentiation methylation histone arginine methylation protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N symmetric methyltransferase activity protein-arginine omega-N symmetric methyltransferase activity ribonucleoprotein complex binding DNA methylation involved in gamete generation histone methyltransferase activity (H4-R3 specific) |
|
| TC1300000246.mm.2 |
H3c8 |
H3 clustered histone 8 |
13 |
23535417 |
NM_145073, BC125355, BC125357 NM_145073, BC125355, BC125357 NM_145073, BC125355, BC125357 |
97908 |
28 |
nuclear chromosome nucleosome nucleus nucleoplasm nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC1900001203.mm.2 |
Psat1 |
phosphoserine aminotransferase 1 |
19 |
-15905122, -15905122 |
NM_001205339, NM_177420, BC004827 NM_001205339, NM_177420, BC004827 NM_001205339, NM_177420, BC004827 |
107272 |
34 |
catalytic activity O-phospho-L-serine:2-oxoglutarate aminotransferase activity cytoplasm cytosol L-serine biosynthetic process transaminase activity cellular amino acid biosynthetic process transferase activity pyridoxal phosphate binding identical protein binding |
00260 00750 01100 |
| TC1100004229.mm.2 |
Cbr2 |
carbonyl reductase 2 |
11 |
-120729484 |
NM_007621, BC010758 NM_007621, BC010758 |
12409 |
25 |
carbonyl reductase (NADPH) activity carbonyl reductase (NADPH) activity carbonyl reductase (NADPH) activity protein binding mitochondrion xylulose metabolic process glucose metabolic process NADH oxidation oxidoreductase activity identical protein binding protein self-association L-xylulose reductase (NADP+) activity |
00590 01100 |
| TC0100003478.mm.2 |
Uck2 |
uridine-cytidine kinase 2 |
1 |
-167226083 |
NM_030724, BC023789 NM_030724, BC023789 |
80914 |
24 |
nucleotide binding uridine kinase activity protein binding ATP binding cytoplasm cytosol cytosol CMP salvage phosphorylation transferase activity nucleoside kinase activity identical protein binding intracellular membrane-bounded organelle UMP salvage |
00240 00983 01100 |
| TC0200002532.mm.2 |
Ube2c |
ubiquitin-conjugating enzyme E2C |
2 |
164769928 |
NM_026785, BC147032, BC147033 NM_026785, BC147032, BC147033 NM_026785, BC147032, BC147033 |
68612 |
25 |
ubiquitin ligase complex nucleotide binding protein polyubiquitination ubiquitin-protein transferase activity ATP binding nucleus anaphase-promoting complex cytosol plasma membrane ubiquitin-dependent protein catabolic process cell cycle exit from mitosis free ubiquitin chain polymerization protein ubiquitination transferase activity regulation of mitotic metaphase/anaphase transition anaphase-promoting complex-dependent catabolic process anaphase-promoting complex-dependent catabolic process positive regulation of exit from mitosis ubiquitin-like protein ligase binding cell division ubiquitin conjugating enzyme activity ubiquitin conjugating enzyme activity protein K48-linked ubiquitination protein K11-linked ubiquitination |
04120 |
| TC0600001606.mm.2 |
Emp1 |
epithelial membrane protein 1 |
6 |
135362930, 135367492 |
NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 NM_001288627, NM_001288628, NM_010128, BC034257, BC046299, BC050899, BC138491 |
13730 |
29 |
plasma membrane plasma membrane cell death membrane integral component of membrane cell growth bleb assembly |
|
| TC1300001558.mm.2 |
H2ac15 |
H2A clustered histone 15 |
13 |
-21753376 |
NM_178183, BC119335 NM_178183, BC119335 |
319169 |
7 |
nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity |
05322 |
| TC1300001561.mm.2 |
H3c11 |
H3 clustered histone 11 |
13 |
-21782914 |
NM_178207, BC116383 NM_178207, BC116383 |
319153 |
10 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC0800001094.mm.2 |
Mt2 |
metallothionein 2 |
8 |
94172617 |
NM_008630, BC031758 NM_008630, BC031758 |
17750 |
217 |
nucleus cytoplasm cytosol cellular zinc ion homeostasis cellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding response to bacterium detoxification of copper ion detoxification of copper ion metal ion binding cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion |
|
| TC0100003193.mm.2 |
Cfh |
complement component factor h |
1 |
-140085854 |
NM_009888, BC066092 NM_009888, BC066092 |
12628 |
153 |
angiogenesis neutrophil homeostasis kidney development kidney development complement component C3b binding activation of membrane attack complex response to dietary excess organ or tissue specific immune response immune system process immune complex clearance retinal pigment epithelium development protein binding extracellular region extracellular space extracellular space extracellular space nucleus cytoplasm plasma membrane inflammatory response inflammatory response immune response complement activation complement activation complement activation complement activation complement activation, alternative pathway complement activation, alternative pathway mitochondrion organization visual perception heparin binding heparin binding determination of adult lifespan external side of plasma membrane gene expression immunoglobulin mediated immune response axon regulation of complement activation regulation of complement activation mitochondrial DNA metabolic process glomerulus development glomerulus development response to cytokine vascular associated smooth muscle cell differentiation vascular associated smooth muscle cell differentiation identical protein binding neuronal cell body heparan sulfate proteoglycan binding innate immune response ATP metabolic process photoreceptor cell differentiation retinal rod cell development neuromuscular process cartilage development organelle localization retina development in camera-type eye retina development in camera-type eye bone development monocyte aggregation platelet aggregation cellular response to lipopolysaccharide inflammatory response to wounding creatinine homeostasis mitochondrial gene expression regulation of complement-dependent cytotoxicity |
04610 05150 |
| TC0600001433.mm.2 |
Cdca3 |
cell division cycle associated 3 |
6 |
124830175 |
NM_013538, BC002006 NM_013538, BC002006 |
14793 |
23 |
molecular_function cytoplasm adherens junction cell cycle cell division |
|
| TC1000003117.mm.2 |
Shmt2 |
serine hydroxymethyltransferase 2 (mitochondrial) |
10 |
-127517122 |
NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396 NM_001252316, NM_028230, BC004825, BC051396 |
108037 |
33 |
translation repressor activity, mRNA regulatory element binding regulation of oxidative phosphorylation regulation of oxidative phosphorylation regulation of oxidative phosphorylation chromatin binding catalytic activity glycine hydroxymethyltransferase activity glycine hydroxymethyltransferase activity nucleus nucleus cytoplasm cytoplasm mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane mitochondrial intermembrane space mitochondrial matrix mitochondrial matrix cytosol glycine metabolic process glycine biosynthetic process L-serine metabolic process L-serine biosynthetic process L-serine catabolic process one-carbon metabolic process one-carbon metabolic process zinc ion binding positive regulation of cell population proliferation L-allo-threonine aldolase activity purine nucleobase biosynthetic process microtubule cytoskeleton membrane amino acid binding transferase activity glycine biosynthetic process from serine glycine biosynthetic process from serine pyridoxal phosphate binding pyridoxal phosphate binding response to type I interferon response to type I interferon tetrahydrofolate interconversion mitochondrial nucleoid identical protein binding protein homodimerization activity tetrahydrofolate metabolic process tetrahydrofolate metabolic process folic acid metabolic process mRNA 5'-UTR binding cobalt ion binding protein tetramerization protein homotetramerization protein homotetramerization regulation of mitochondrial translation regulation of mitochondrial translation protein K63-linked deubiquitination BRISC complex BRISC complex serine binding regulation of aerobic respiration regulation of aerobic respiration |
00260 00460 00670 01100 |
| TSUnmapped00000029.mm.2 |
Psd3 |
pleckstrin and Sec7 domain containing 3 |
8 |
-67689081, -67689081, -67689081 |
NM_177698 |
234353 |
22 |
guanyl-nucleotide exchange factor activity plasma membrane membrane cell junction ARF protein signal transduction regulation of ARF protein signal transduction ruffle membrane ruffle membrane cell projection synapse |
04144 |
| TC0800001095.mm.2 |
Mt1 |
metallothionein 1 |
8 |
94179088 |
NM_013602, BC027262, BC036990 NM_013602, BC027262, BC036990 NM_013602, BC027262, BC036990 |
17748 |
335 |
copper ion binding nucleus cytoplasm lysosome cytosol cytosol cellular metal ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding detoxification of copper ion detoxification of copper ion negative regulation of neuron apoptotic process metal ion binding metal ion binding cellular response to chromate cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion cellular response to zinc ion |
|
| TC1300000174.mm.2 |
H3c10 |
H3 clustered histone 10 |
13 |
21717627 |
NM_178206 |
319152 |
3 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC1300001633.mm.2 |
H3c6 |
H3 clustered histone 6 |
13 |
-23561474 |
NM_178205, BC156786 NM_178205, BC156786 |
319151 |
11 |
nuclear chromosome chromatin nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC1500000031.mm.2 |
Dab2 |
disabled 2, mitogen-responsive phosphoprotein |
15 |
6386747, 6299788 |
NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 NM_001008702, NM_001037905, NM_001102400, NM_023118, BC006588, BC016887 |
13132 |
118 |
negative regulation of transcription by RNA polymerase II cell morphogenesis involved in differentiation fibrillar center in utero embryonic development positive regulation of receptor recycling positive regulation of protein phosphorylation positive regulation of receptor internalization integrin binding protein binding phosphatidylinositol-4,5-bisphosphate binding nucleus cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis pinocytosis apoptotic process activation of JUN kinase activity multicellular organism development endoderm development excretion protein C-terminus binding positive regulation of epithelial to mesenchymal transition positive regulation of epithelial to mesenchymal transition positive regulation of pathway-restricted SMAD protein phosphorylation positive regulation of pathway-restricted SMAD protein phosphorylation negative regulation of neuron projection development protein transport membrane Wnt signaling pathway apical plasma membrane myeloid cell differentiation clathrin coat of coated pit clathrin-coated vesicle cell differentiation clathrin binding negative regulation of cell growth positive regulation of cell migration positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway clathrin-coated vesicle membrane cytoplasmic vesicle negative regulation of protein binding positive regulation of aldosterone biosynthetic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of transcription elongation from RNA polymerase II promoter leading edge cell differentiation phosphatidylinositol binding AP-2 adaptor complex binding clathrin adaptor activity clathrin adaptor activity cargo receptor activity cargo receptor activity negative regulation of apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle positive regulation of cell adhesion positive regulation of cell adhesion positive regulation of endocytosis positive regulation of endocytosis positive regulation of transcription by RNA polymerase II SMAD binding clathrin coat assembly clathrin coat assembly perinuclear region of cytoplasm response to steroid hormone negative regulation of epithelial cell proliferation low-density lipoprotein particle receptor binding positive regulation of SMAD protein signal transduction negative regulation of androgen receptor signaling pathway negative regulation of ERK1 and ERK2 cascade cellular response to epidermal growth factor stimulus hematopoietic stem cell proliferation cellular response to transforming growth factor beta stimulus negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading negative regulation of protein localization to plasma membrane negative regulation of protein localization to plasma membrane positive regulation of Wnt signaling pathway, planar cell polarity pathway regulation of Rho-dependent protein serine/threonine kinase activity positive regulation of clathrin-dependent endocytosis positive regulation of clathrin-dependent endocytosis positive regulation of early endosome to late endosome transport positive regulation of aldosterone secretion positive regulation of integrin-mediated signaling pathway negative regulation of extrinsic apoptotic signaling pathway |
04144 |
| TC0300001137.mm.2 |
Sort1 |
sortilin 1 |
3 |
108284063 |
NM_001271599, NM_019972, BC056343 NM_001271599, NM_019972, BC056343 NM_001271599, NM_019972, BC056343 |
20661 |
120 |
ossification protein binding nucleus lysosome endosome early endosome endoplasmic reticulum Golgi apparatus Golgi apparatus cytosol plasma membrane plasma membrane clathrin-coated pit protein targeting to lysosome post-Golgi vesicle-mediated transport Golgi to endosome transport Golgi to endosome transport endocytosis endocytosis endocytosis G protein-coupled receptor signaling pathway neuropeptide signaling pathway multicellular organism development endosome to lysosome transport extrinsic apoptotic signaling pathway via death domain receptors cell surface endosome membrane nerve growth factor receptor activity regulation of gene expression myotube differentiation myotube differentiation membrane integral component of membrane integral component of membrane vesicle organization vesicle organization vesicle organization enzyme binding clathrin-coated vesicle trans-Golgi network transport vesicle cell differentiation neurotensin receptor activity, non-G protein-coupled dendrite cytoplasmic vesicle membrane cytoplasmic vesicle endosome transport via multivesicular body sorting pathway response to insulin response to insulin neuronal cell body intracellular membrane-bounded organelle negative regulation of fat cell differentiation glucose import glucose import neurotrophin TRK receptor signaling pathway plasma membrane to endosome transport nerve growth factor binding perinuclear region of cytoplasm negative regulation of lipoprotein lipase activity Golgi to lysosome transport positive regulation of epithelial cell apoptotic process retromer complex binding |
04142 04722 |
| TC1300000262.mm.2 |
H1f1 |
H1.1 linker histone, cluster member |
13 |
23763667 |
NM_030609, BC116820, BC116850 NM_030609, BC116820, BC116850 NM_030609, BC116820, BC116850 |
80838 |
42 |
nucleosome DNA binding double-stranded DNA binding protein binding nucleus nucleus chromosome nucleosome assembly spermatogenesis spermatogenesis heparin binding cell surface nucleosome positioning chromosome condensation nucleosomal DNA binding negative regulation of chromatin silencing vesicle negative regulation of DNA recombination positive regulation of receptor-mediated endocytosis |
|
| TC0300000627.mm.2 |
Gask1b |
golgi associated kinase 1B |
3 |
79885929 |
NM_133187, BC056975 NM_133187, BC056975 |
68659 |
14 |
molecular_function Golgi apparatus biological_process membrane integral component of membrane |
|
| TC0700003592.mm.2 |
Man2a2 |
mannosidase 2, alpha 2 |
7 |
-80349096 |
NM_172903, BC055006 NM_172903, BC055006 |
140481 |
23 |
Golgi membrane catalytic activity alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing protein deglycosylation metabolic process mannosidase activity membrane integral component of membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding |
00510 01100 |
| TC1100003118.mm.2 |
C1qbp |
complement component 1, q subcomponent binding protein |
11 |
-70977845 |
NM_007573, BC038075 NM_007573, BC038075 |
12261 |
67 |
negative regulation of transcription by RNA polymerase II complement component C1q complex binding complement component C1q complex binding adaptive immune response immune system process transcription corepressor activity transcription corepressor activity mRNA binding mRNA binding protein kinase C binding protein binding hyaluronic acid binding hyaluronic acid binding extracellular region extracellular space nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial matrix cytosol plasma membrane plasma membrane mRNA processing apoptotic process complement activation, classical pathway transcription factor binding transcription factor binding RNA splicing translation activator activity cell surface cell surface phosphatidylinositol 3-kinase signaling membrane regulation of complement activation regulation of complement activation kininogen binding kininogen binding adrenergic receptor binding negative regulation of interferon-gamma production negative regulation of interleukin-12 production negative regulation of MDA-5 signaling pathway negative regulation of RIG-I signaling pathway ribosome biogenesis mature ribosome assembly mature ribosome assembly mature ribosome assembly positive regulation of apoptotic process innate immune response positive regulation of cell adhesion negative regulation of mRNA splicing, via spliceosome negative regulation of mRNA splicing, via spliceosome presynaptic active zone negative regulation of defense response to virus positive regulation of protein kinase B signaling positive regulation of mitochondrial translation positive regulation of mitochondrial translation positive regulation of neutrophil chemotaxis mitochondrial ribosome binding mitochondrial ribosome binding presynapse glutamatergic synapse GABA-ergic synapse positive regulation of substrate adhesion-dependent cell spreading positive regulation of trophoblast cell migration positive regulation of dendritic cell chemotaxis |
|
| TC1500000175.mm.2 |
|
|
|
|
NM_020332, NR_106065, BC054379 NM_020332, NR_106065, BC054379 NM_020332, NR_106065, BC054379 |
|
|
inorganic phosphate transmembrane transporter activity inorganic phosphate transmembrane transporter activity plasma membrane integral component of plasma membrane integral component of plasma membrane phosphate ion transport phosphate ion transmembrane transporter activity membrane integral component of membrane integral component of membrane regulation of bone mineralization inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity phosphate ion transmembrane transport |
|
| TC0500003472.mm.2 |
|
|
|
|
NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 NM_008568, NR_029749, NR_029787, BC065164, BC066024 |
|
|
nucleotide binding double-strand break repair via break-induced replication in utero embryonic development negative regulation of B cell apoptotic process DNA binding DNA helicase activity DNA helicase activity DNA replication origin binding single-stranded DNA binding single-stranded DNA binding helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromosome cytosol DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cellular response to DNA damage stimulus cell cycle cell aging sensory perception of sound cell population proliferation Wnt signaling pathway hydrolase activity regulation of phosphorylation MCM complex MCM complex negative regulation of apoptotic process regulation of viral genome replication regulation of viral genome replication long-term synaptic potentiation SMAD protein signal transduction cellular response to inorganic substance cellular response to xenobiotic stimulus cellular response to forskolin single-stranded 3'-5' DNA helicase activity |
|
| TC0200002990.mm.2 |
Hacd1 |
3-hydroxyacyl-CoA dehydratase 1 |
2 |
-14026830 |
NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017 NM_001012396, NM_013935, BC138116, BC141017 |
30963 |
14 |
endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process multicellular organism development regulation of G2/M transition of mitotic cell cycle positive regulation of cell-substrate adhesion myotube differentiation membrane integral component of membrane lyase activity 3-hydroxyacyl-CoA dehydratase activity 3-hydroxyacyl-CoA dehydratase activity enzyme binding sphingolipid biosynthetic process sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation cellular protein-containing complex assembly very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process hydroxyapatite binding cementum mineralization 3-hydroxy-arachidoyl-CoA dehydratase activity 3-hydroxy-behenoyl-CoA dehydratase activity 3-hydroxy-lignoceroyl-CoA dehydratase activity regulation of G1/S transition of mitotic cell cycle |
|
| TC1800000291.mm.2 |
Kif20a |
kinesin family member 20A |
18 |
34624935, 34624623, 34625032 |
NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608 NM_001166406, NM_001166407, NM_009004, BC060608 |
19348 |
33 |
nucleotide binding mitotic cytokinesis microtubule bundle formation microtubule motor activity ATP binding nucleus nucleoplasm cytoplasm Golgi apparatus spindle cytoskeleton kinesin complex microtubule microtubule-based movement microtubule binding protein transport ATPase activity protein kinase binding midbody cleavage furrow regulation of cytokinesis intercellular bridge midbody abscission |
|
| TC0700004624.mm.2 |
Plk1 |
polo like kinase 1 |
7 |
122159434 |
NM_011121, BC006880 NM_011121, BC006880 |
18817 |
147 |
mitotic sister chromatid segregation G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II establishment of mitotic spindle orientation nucleotide binding mitotic cell cycle mitotic cell cycle mitotic cytokinesis magnesium ion binding chromosome, centromeric region kinetochore kinetochore condensed chromosome, centromeric region chromatin synaptonemal complex spindle pole spindle pole condensed nuclear chromosome outer kinetochore microtubule bundle formation protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus chromosome cytoplasm cytoplasm centrosome centrosome centriole spindle cytoskeleton spindle microtubule protein phosphorylation protein phosphorylation cell cycle mitotic spindle assembly checkpoint centrosome cycle regulation of mitotic cell cycle microtubule binding positive regulation of peptidyl-threonine phosphorylation anaphase-promoting complex binding microtubule cytoskeleton kinase activity phosphorylation female meiosis chromosome segregation protein ubiquitination transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-serine phosphorylation protein kinase binding regulation of mitotic metaphase/anaphase transition midbody protein destabilization positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of cytokinesis regulation of cytokinesis protein localization to organelle centriolar satellite polar body extrusion after meiotic divisions identical protein binding negative regulation of apoptotic process regulation of protein binding regulation of protein binding homologous chromosome segregation establishment of protein localization negative regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of proteolysis nuclear envelope disassembly spindle midzone cell division positive regulation of ubiquitin-protein transferase activity synaptonemal complex disassembly protein localization to chromatin signal transduction involved in G2 DNA damage checkpoint protein localization to nuclear envelope mitotic spindle pole regulation of mitotic spindle assembly positive regulation of ubiquitin protein ligase activity regulation of protein localization to cell cortex |
04110 04114 04914 |
| TC1700000036.mm.2 |
Zdhhc14 |
zinc finger, DHHC domain containing 14 |
17 |
5492599 |
NM_146073, BC059814 NM_146073, BC059814 |
224454 |
19 |
endoplasmic reticulum endoplasmic reticulum Golgi apparatus protein targeting to membrane membrane integral component of membrane palmitoyltransferase activity transferase activity transferase activity, transferring acyl groups peptidyl-L-cysteine S-palmitoylation peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein-cysteine S-palmitoyltransferase activity |
|
| TC0400003366.mm.2 |
Kif2c |
kinesin family member 2C |
4 |
-117159632, -117159635 |
NM_134471, BC006841 NM_134471, BC006841 |
73804 |
32 |
nucleotide binding chromosome, centromeric region chromosome, centromeric region kinetochore microtubule motor activity ATP binding nucleus chromosome cytoplasm centrosome spindle cytoskeleton kinesin complex microtubule microtubule-based movement microtubule depolymerization cell cycle chromosome segregation mitotic metaphase plate congression microtubule binding microtubule cytoskeleton ATPase activity establishment or maintenance of microtubule cytoskeleton polarity microtubule plus-end microtubule plus-end binding cell division metaphase plate congression attachment of mitotic spindle microtubules to kinetochore regulation of chromosome segregation |
|
| TC1400000176.mm.2 |
Plau |
plasminogen activator, urokinase |
14 |
20836661 |
NM_008873, BC120709, BC120713 NM_008873, BC120709, BC120713 NM_008873, BC120709, BC120713 |
18792 |
311 |
angiogenesis response to hypoxia serine-type endopeptidase activity protein binding extracellular region extracellular space extracellular space proteolysis peptidase activity serine-type peptidase activity positive regulation of cell population proliferation cell surface regulation of signaling receptor activity smooth muscle cell migration regulation of smooth muscle cell migration positive regulation of smooth muscle cell migration membrane hydrolase activity positive regulation of cell migration plasminogen activation plasminogen activation regulation of cell adhesion mediated by integrin regulation of cell adhesion mediated by integrin wound healing regulation of cell population proliferation fibrinolysis fibrinolysis skeletal muscle tissue regeneration positive regulation of ovulation neuron death regulation of smooth muscle cell-matrix adhesion regulation of hepatocyte proliferation positive regulation of reactive oxygen species metabolic process |
04610 |
| TC1000002650.mm.2 |
Utp20 |
UTP20 small subunit processome component |
10 |
-88746606 |
NM_175158 |
70683 |
20 |
nucleus nucleolus nucleolus plasma membrane rRNA processing 90S preribosome small-subunit processome |
|
| TC0900000659.mm.2 |
Idh3a |
isocitrate dehydrogenase 3 (NAD+) alpha |
9 |
54586510 |
NM_029573, BC034273, BC049956 NM_029573, BC034273, BC049956 NM_029573, BC034273, BC049956 |
67834 |
40 |
magnesium ion binding isocitrate dehydrogenase (NAD+) activity isocitrate dehydrogenase (NAD+) activity mitochondrion mitochondrion mitochondrion tricarboxylic acid cycle tricarboxylic acid cycle isocitrate metabolic process isocitrate metabolic process 2-oxoglutarate metabolic process NADH metabolic process oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor myelin sheath metal ion binding NAD binding |
00020 01100 |
| TC0100000476.mm.2 |
Cd28 |
CD28 antigen |
1 |
60746387 |
NM_007642, BC064058, CD28 NM_007642, BC064058, CD28 NM_007642, BC064058, CD28 |
12487 |
502 |
immunological synapse protease binding positive regulation of inflammatory response to antigenic stimulus plasma membrane immune response external side of plasma membrane external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface positive regulation of gene expression negative regulation of gene expression positive regulation of phosphatidylinositol 3-kinase signaling membrane integral component of membrane protein kinase binding T cell costimulation T cell costimulation T cell costimulation T cell costimulation T cell costimulation positive regulation of interleukin-10 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation T cell activation T cell activation regulation of T cell proliferation identical protein binding negative thymic T cell selection regulatory T cell differentiation membrane raft regulation of regulatory T cell differentiation positive regulation of mitotic nuclear division positive regulation of transcription by RNA polymerase II positive regulation of alpha-beta T cell proliferation positive regulation of alpha-beta T cell proliferation positive regulation of isotype switching to IgG isotypes T cell receptor signaling pathway T cell receptor signaling pathway positive regulation of protein kinase B signaling apoptotic signaling pathway protein complex involved in cell adhesion |
04514 04660 04672 04940 05320 05322 05323 05330 05332 05416 |
| TC0200004511.mm.2 |
Gatm |
glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
2 |
-122594472 |
NM_025961, BC003879 NM_025961, BC003879 |
67092 |
37 |
mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial intermembrane space creatine metabolic process creatine biosynthetic process creatine biosynthetic process multicellular organism development response to nutrient learning or memory response to organic substance muscle atrophy amidinotransferase activity amidinotransferase activity glycine amidinotransferase activity membrane transferase activity response to peptide hormone response to mercury ion positive regulation of cold-induced thermogenesis |
00260 00330 01100 |
| TC1600000447.mm.2 |
Tfrc |
transferrin receptor |
16 |
32608895, 32609121 |
NM_011638, BC054522 NM_011638, BC054522 |
22042 |
174 |
positive regulation of protein phosphorylation double-stranded RNA binding transferrin receptor activity transferrin receptor activity iron ion transmembrane transporter activity protein binding extracellular region extracellular space nucleus cytoplasm mitochondrion endosome endosome early endosome plasma membrane plasma membrane integral component of plasma membrane clathrin-coated pit clathrin-coated pit iron ion transport iron ion transport cellular iron ion homeostasis cellular iron ion homeostasis endocytosis receptor-mediated endocytosis external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface endosome membrane positive regulation of gene expression negative regulation of mitochondrial fusion membrane membrane integral component of membrane basolateral plasma membrane protein kinase binding osteoclast differentiation Hsp70 protein binding positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of protein-containing complex assembly cytoplasmic vesicle receptor internalization cellular response to extracellular stimulus positive regulation of peptidyl-serine phosphorylation transferrin transport intracellular signal transduction cellular response to drug positive regulation of T cell proliferation positive regulation of T cell proliferation identical protein binding protein homodimerization activity negative regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling intracellular membrane-bounded organelle protein-containing complex binding positive regulation of bone resorption positive regulation of isotype switching perinuclear region of cytoplasm perinuclear region of cytoplasm chaperone binding positive regulation of NF-kappaB transcription factor activity recycling endosome recycling endosome recycling endosome membrane extracellular exosome extracellular exosome cellular response to iron ion positive regulation of protein localization to nucleus HFE-transferrin receptor complex HFE-transferrin receptor complex cellular response to leukemia inhibitory factor |
04144 04145 04640 |
| TC0200000603.mm.2 |
Angptl2 |
angiopoietin-like 2 |
2 |
33215960 |
NM_011923, BC138609, BC138610 NM_011923, BC138609, BC138610 NM_011923, BC138609, BC138610 |
26360 |
53 |
angiogenesis signaling receptor binding extracellular region extracellular space extracellular space collagen-containing extracellular matrix |
|
| TC0900000505.mm.2 |
H2ax |
H2A.X variant histone |
9 |
44334714 |
NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A, NM_010436, BC005468, BC010336, H2A, |
15270 |
476 |
double-strand break repair via homologous recombination chromosome, telomeric region chromatin nucleosome condensed nuclear chromosome male germ cell nucleus XY body DNA binding damaged DNA binding protein binding nucleus nucleus nucleoplasm nucleoplasm replication fork chromosome centrosome DNA repair DNA repair DNA recombination chromatin silencing cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle spermatogenesis nuclear speck enzyme binding site of double-strand break site of double-strand break histone binding protein heterodimerization activity meiotic cell cycle cellular response to gamma radiation site of DNA damage |
05322 |
| TC1400000322.mm.2 |
Nt5dc2 |
5'-nucleotidase domain containing 2 |
14 |
31134735, 31131088 |
NM_027289, BC011230 NM_027289, BC011230 |
70021 |
17 |
cellular_component 5'-nucleotidase activity |
|
| TC0300000934.mm.2 |
H3c13 |
H3 clustered histone 13 |
3 |
96268653 |
NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965 NM_178215, BC139251, BC139252, BC156965 |
319154 |
5 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC1200002396.mm.2 |
Cinp |
cyclin-dependent kinase 2 interacting protein |
12 |
-110872609 |
NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867 NM_026048, NM_027223, BC011066, BC021867 |
67236 |
17 |
molecular_function cellular_component nucleus DNA replication DNA repair cellular response to DNA damage stimulus cell cycle biological_process cell division |
|
| TC1000000422.mm.2 |
Prep |
prolyl endopeptidase |
10 |
45067215 |
NM_011156, BC012869, BC050830 NM_011156, BC012869, BC050830 NM_011156, BC012869, BC050830 |
19072 |
58 |
endopeptidase activity endopeptidase activity serine-type endopeptidase activity nucleus cytoplasm cytosol cytosol proteolysis peptidase activity serine-type peptidase activity hydrolase activity protein metabolic process peptide binding serine-type exopeptidase activity oligopeptidase activity |
|
| TC1900001266.mm.2 |
Mamdc2 |
MAM domain containing 2 |
19 |
-23302608 |
NM_174857, BC042773 NM_174857, BC042773 |
71738 |
14 |
glycosaminoglycan binding extracellular region interstitial matrix endoplasmic reticulum membrane peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan extracellular matrix |
|
| TC0500000888.mm.2 |
Septin11 |
septin 11 |
5 |
93093415, 93093415 |
NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466 NM_001009818, BC031456, BC062206, BC064466 |
52398 |
38 |
nucleotide binding stress fiber GTPase activity protein binding GTP binding cytoplasm cytoskeleton septin ring cell cycle microtubule cytoskeleton cell junction septin complex septin complex septin complex cell division site cellular protein localization cell projection synapse regulation of synapse organization cell division molecular adaptor activity cytoskeleton-dependent cytokinesis postsynapse glutamatergic synapse GABA-ergic synapse postsynaptic specialization of symmetric synapse |
|
| TC0700000236.mm.2 |
Slc1a5 |
solute carrier family 1 (neutral amino acid transporter), member 5 |
7 |
16781345 |
NM_009201, BC029873, BC037462 NM_009201, BC029873, BC037462 NM_009201, BC029873, BC037462 |
20514 |
33 |
plasma membrane plasma membrane amino acid transport glutamine transport basal plasma membrane glutamine secretion neutral amino acid transmembrane transporter activity L-aspartate transmembrane transporter activity L-aspartate transmembrane transporter activity L-glutamine transmembrane transporter activity L-serine transmembrane transporter activity symporter activity L-serine transport membrane integral component of membrane metal ion binding protein homotrimerization L-aspartate import across plasma membrane L-aspartate import across plasma membrane transport across blood-brain barrier L-glutamine import across plasma membrane |
04974 |
| TC0900002503.mm.2 |
Hacd3 |
3-hydroxyacyl-CoA dehydratase 3 |
9 |
-64986982 |
NM_021345, BC031755, BC057023 NM_021345, BC031755, BC057023 NM_021345, BC031755, BC057023 |
57874 |
26 |
protein binding endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process I-kappaB kinase/NF-kappaB signaling JNK cascade Rho protein signal transduction membrane integral component of membrane lyase activity 3-hydroxyacyl-CoA dehydratase activity 3-hydroxyacyl-CoA dehydratase activity enzyme binding sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation nuclear membrane very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process positive regulation of viral genome replication positive regulation by virus of viral protein levels in host cell 3-hydroxy-arachidoyl-CoA dehydratase activity 3-hydroxy-behenoyl-CoA dehydratase activity 3-hydroxy-lignoceroyl-CoA dehydratase activity |
|
| TC1200000664.mm.2 |
Rhoj |
ras homolog family member J |
12 |
75308312 |
NM_023275, BC043719 NM_023275, BC043719 |
80837 |
34 |
nucleotide binding angiogenesis GTPase activity GTPase activity GTPase activity protein binding GTP binding GTP binding intracellular anatomical structure plasma membrane endocytosis small GTPase mediated signal transduction Rho protein signal transduction regulation of cell shape regulation of endothelial cell migration membrane cell migration cell projection assembly actin cytoskeleton organization actin cytoskeleton organization Cdc42 protein signal transduction retina vasculature morphogenesis in camera-type eye positive regulation of cell migration involved in sprouting angiogenesis regulation of sprouting angiogenesis |
|
| TC0100002974.mm.2 |
Ddx18 |
DEAD box helicase 18 |
1 |
-121553834 |
NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 NM_025860, BC028246, BC103776, BC141230, BC141231 |
66942 |
25 |
nucleotide binding maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleic acid binding RNA binding helicase activity ATP binding nucleus chromosome nucleolus nucleolus hydrolase activity |
|
| TC1100003561.mm.2 |
Abcc3 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
11 |
-94343294 |
NM_029600, BC150788 NM_029600, BC150788 |
76408 |
46 |
nucleotide binding ATP binding plasma membrane integral component of plasma membrane drug transmembrane transport ABC-type xenobiotic transporter activity glucuronoside transmembrane transporter activity ABC-type glutathione S-conjugate transporter activity ABC-type bile acid transporter activity bile acid and bile salt transport canalicular bile acid transport membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane ATPase activity transmembrane transporter activity ATPase-coupled transmembrane transporter activity ATPase-coupled transmembrane transporter activity xenobiotic transport xenobiotic transmembrane transporter activity transmembrane transport transmembrane transport icosanoid transmembrane transporter activity leukotriene transport anion transmembrane transport |
02010 04976 |
| TC1300000245.mm.2 |
H2ac10 |
H2A clustered histone 10 |
13 |
23533874 |
NM_175661, BC125011 NM_175661, BC125011 |
319173 |
10 |
nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity |
05322 |
| TC1300002037.mm.2 |
Cltb |
clathrin, light polypeptide (Lcb) |
13 |
-54592385 |
NM_028870, BC070404 NM_028870, BC070404 |
74325 |
32 |
structural molecule activity trans-Golgi network cytosol plasma membrane plasma membrane plasma membrane clathrin-coated pit intracellular protein transport membrane vesicle-mediated transport clathrin coat clathrin vesicle coat clathrin coat of trans-Golgi network vesicle clathrin coat of coated pit synaptic vesicle membrane synaptic vesicle membrane cytoplasmic vesicle clathrin heavy chain binding peptide binding intracellular membrane-bounded organelle clathrin coat assembly ciliary membrane clathrin-dependent endocytosis presynaptic endocytic zone membrane postsynaptic endocytic zone cytoplasmic component |
04142 04144 05016 05100 |
| TC1600000335.mm.2 |
St6gal1 |
beta galactoside alpha 2,6 sialyltransferase 1 |
16 |
23226020, 23290469, 23224739 |
NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 NM_001252505, NM_001252506, NM_145933, BC027833, BC092222, BC096026 |
20440 |
78 |
Golgi trans cisterna Golgi membrane beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity extracellular region endoplasmic reticulum Golgi apparatus Golgi medial cisterna N-acetylneuraminate metabolic process protein glycosylation sialyltransferase activity sialyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine positive regulation of mononuclear cell proliferation protein homodimerization activity negative regulation of chemotaxis sialylation regulation of substrate adhesion-dependent cell spreading protein sialylation negative regulation of macrophage apoptotic process |
00510 00514 01100 |
| TC1300001576.mm.2 |
|
|
|
|
NM_178186, BC065803, BC116373 NM_178186, BC065803, BC116373 NM_178186, BC065803, BC116373 |
|
|
DNA binding nucleus chromatin silencing negative regulation of cell population proliferation |
|
| TC0300002313.mm.2 |
Lmna |
lamin A |
3 |
-88481147, -88483204, -88483204 |
NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 NM_001002011, NM_001111102, NM_019390, BC015302, BC094020 |
16905 |
327 |
protein binding nucleus nucleus nuclear envelope nuclear envelope nuclear envelope lamin filament nucleoplasm nucleoplasm cytosol intermediate filament protein import into nucleus nucleus organization nucleus organization nuclear envelope organization nuclear envelope organization muscle organ development protein phosphatase 1 binding negative regulation of cell population proliferation positive regulation of gene expression nuclear matrix nuclear body nuclear speck establishment of cell polarity regulation of cell migration establishment or maintenance of microtubule cytoskeleton polarity regulation of protein stability nuclear membrane regulation of telomere maintenance protein localization to nucleus cellular protein localization site of double-strand break identical protein binding positive regulation of osteoblast differentiation perinuclear region of cytoplasm ventricular cardiac muscle cell development negative regulation of mesenchymal cell proliferation negative regulation of release of cytochrome c from mitochondria positive regulation of cell aging positive regulation of histone H3-K9 trimethylation negative regulation of cardiac muscle hypertrophy in response to stress negative regulation of adipose tissue development DNA double-strand break attachment to nuclear envelope negative regulation of extrinsic apoptotic signaling pathway |
05410 05412 05414 |
| TC0600002404.mm.2 |
Hpgds |
hematopoietic prostaglandin D synthase |
6 |
-65117292 |
NM_019455, BC116735, BC116737 NM_019455, BC116735, BC116737 NM_019455, BC116735, BC116737 |
54486 |
47 |
magnesium ion binding prostaglandin biosynthetic process glutathione transferase activity glutathione transferase activity prostaglandin-D synthase activity prostaglandin-D synthase activity calcium ion binding nucleoplasm cytoplasm cytosol lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process prostaglandin metabolic process prostaglandin metabolic process glutathione metabolic process transferase activity isomerase activity protein homodimerization activity intracellular membrane-bounded organelle negative regulation of male germ cell proliferation |
00590 01100 |
| TC1300000181.mm.2 |
|
|
|
|
NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 NM_001177544, NM_178185, BC116373, BC127164, BC134370, BC062251, BC090402, BC110626, BC133661, BC147161, BC147162 |
|
|
nucleosome DNA binding nucleus nucleus chromosome chromatin silencing negative regulation of cell population proliferation protein heterodimerization activity |
|
| TC1300001565.mm.2 |
|
|
|
|
NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 NM_001177544, NM_178185, BC062251, BC090402, BC110626, BC116373, BC127164, BC133661, BC134370, BC147161, BC147162 |
|
|
nucleosome DNA binding nucleus nucleus chromosome chromatin silencing negative regulation of cell population proliferation protein heterodimerization activity |
|
| TC0600003268.mm.2 |
Ybx3 |
Y box protein 3 |
6 |
-131364857 |
NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 NM_011733, NM_139117, BC027785, BC048242, BC062377 |
56449 |
53 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific in utero embryonic development nucleic acid binding DNA binding single-stranded DNA binding single-stranded DNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleus cytoplasm cytosol gap junction spermatogenesis male gonad development fertilization regulation of gene expression ribonucleoprotein complex binding negative regulation of apoptotic process positive regulation of organ growth negative regulation of skeletal muscle tissue development negative regulation of necroptotic process cellular response to tumor necrosis factor cellular hyperosmotic response negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress polysome binding |
04530 |
| TC0900000051.mm.2 |
Mmp27 |
matrix metallopeptidase 27 |
9 |
7571395 |
NM_001030289 |
234911 |
12 |
metalloendopeptidase activity extracellular matrix organization collagen catabolic process extrinsic component of endoplasmic reticulum membrane |
|
| TC1300001837.mm.2 |
Eef1e1 |
eukaryotic translation elongation factor 1 epsilon 1 |
13 |
-38645690 |
NM_025380, BC048466 NM_025380, BC048466 |
66143 |
27 |
protein binding nucleus nucleoplasm nucleolus cytoplasm cytosol translation negative regulation of cell population proliferation aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex positive regulation of apoptotic process positive regulation of DNA damage response, signal transduction by p53 class mediator cellular response to leukemia inhibitory factor positive regulation of cellular senescence positive regulation of apoptotic signaling pathway |
|
| TC1600000650.mm.2 |
Naa50 |
N(alpha)-acetyltransferase 50, NatE catalytic subunit |
16 |
44139808, 44139790 |
NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117 NM_028108, BC046283, BC055846, BC057117 |
72117 |
26 |
peptide alpha-N-acetyltransferase activity protein binding nucleus cytoplasm cytoplasm cytoplasm cytosol N-terminal protein amino acid acetylation N-terminal protein amino acid acetylation mitotic sister chromatid cohesion N-acetyltransferase activity H4 histone acetyltransferase activity histone acetylation transferase activity transferase activity, transferring acyl groups NatA complex NatA complex establishment of mitotic sister chromatid cohesion peptidyl-lysine acetyltransferase activity mitotic sister chromatid cohesion, centromeric |
|
| TC0800000564.mm.2 |
Dctd |
dCMP deaminase |
8 |
48109957, 48110012, 48099091 |
NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 NM_001161515, NM_001161516, NM_178788, NR_027759, BC031719 |
320685 |
16 |
catalytic activity dCMP deaminase activity pyrimidine nucleotide metabolic process dUMP biosynthetic process dTMP biosynthetic process metabolic process zinc ion binding nucleotide biosynthetic process hydrolase activity identical protein binding metal ion binding |
00240 01100 |
| TC1300001562.mm.2 |
H2ac22 |
H2A clustered histone 22 |
13 |
-21786773 |
NM_178184 |
319170 |
4 |
DNA binding nucleus chromatin silencing enzyme binding |
05322 |
| TC0100001387.mm.2 |
|
|
|
|
NM_008131, NR_106194, BC015086 NM_008131, NR_106194, BC015086 NM_008131, NR_106194, BC015086 |
|
|
nucleotide binding magnesium ion binding angiogenesis catalytic activity glutamate-ammonia ligase activity glutamate-ammonia ligase activity protein binding ATP binding cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion endoplasmic reticulum rough endoplasmic reticulum cytosol plasma membrane glutamate metabolic process glutamine biosynthetic process glutamine biosynthetic process nitrogen compound metabolic process cell population proliferation cellular response to starvation response to glucose regulation of endothelial cell migration regulation of endothelial cell migration membrane glutamate binding transferase activity ligase activity protein palmitoylation ammonia assimilation cycle protein-cysteine S-palmitoyltransferase activity manganese ion binding positive regulation of insulin secretion protein-containing complex ribosome biogenesis identical protein binding cell projection neuron projection perikaryon myelin sheath myelin sheath intracellular membrane-bounded organelle axon terminus cell body dynein light chain binding metal ion binding positive regulation of epithelial cell proliferation positive regulation of synaptic transmission, glutamatergic glial cell projection regulation of sprouting angiogenesis regulation of sprouting angiogenesis regulation of protein localization to nucleolus |
|
| TC0800000937.mm.2 |
Asf1b |
anti-silencing function 1B histone chaperone |
8 |
83955693 |
NM_024184, BC003428 NM_024184, BC003428 |
66929 |
23 |
chromatin chromatin blastocyst hatching nucleus nucleoplasm chromatin organization chromatin assembly or disassembly nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly DNA replication-independent nucleosome assembly protein-containing complex histone binding histone binding |
|
| TC1300000623.mm.2 |
Sfxn1 |
sideroflexin 1 |
13 |
54071844 |
NM_027324, BC005743 NM_027324, BC005743 |
14057 |
57 |
mitochondrion mitochondrion mitochondrion mitochondrial inner membrane one-carbon metabolic process ion transport iron ion transport iron ion transport amino acid transport ion transmembrane transporter activity L-serine transmembrane transporter activity L-serine transport membrane integral component of membrane transmembrane transporter activity serine transmembrane transporter activity erythrocyte differentiation integral component of mitochondrial inner membrane integral component of mitochondrial inner membrane D-serine transport D-serine transmembrane transporter activity transmembrane transport serine import into mitochondrion serine import into mitochondrion mitochondrial transmembrane transport |
|
| TC0600001448.mm.2 |
Nop2 |
NOP2 nucleolar protein |
6 |
125131882 |
NM_138747, BC004733, BC007151 NM_138747, BC004733, BC007151 NM_138747, BC004733, BC007151 |
110109 |
37 |
ribosomal large subunit assembly maturation of LSU-rRNA RNA methylation blastocyst formation RNA binding nucleus nucleolus nucleolus rRNA processing methyltransferase activity positive regulation of cell population proliferation S-adenosylmethionine-dependent methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity transferase activity methylation ribosome biogenesis rRNA base methylation regulation of signal transduction by p53 class mediator |
|
| TC0300001076.mm.2 |
Slc16a1 |
solute carrier family 16 (monocarboxylic acid transporters), member 1 |
3 |
104638663 |
NM_009196, BC014777 NM_009196, BC014777 |
20501 |
88 |
mitochondrion centrosome plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane lipid metabolic process centrosome cycle monocarboxylic acid transmembrane transporter activity monocarboxylic acid transmembrane transporter activity basal plasma membrane lactate transmembrane transporter activity symporter activity monocarboxylic acid transport monocarboxylic acid transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane lateral plasma membrane cell junction response to food lactate transmembrane transport plasma membrane lactate transport plasma membrane lactate transport glucose homeostasis identical protein binding intracellular membrane-bounded organelle synapse synapse carboxylic acid transmembrane transporter activity regulation of insulin secretion behavioral response to nutrient transmembrane transport cellular response to organic cyclic compound organic cyclic compound binding carboxylic acid transmembrane transport |
|
| TC1500000432.mm.2 |
Sqle |
squalene epoxidase |
15 |
59315091 |
NM_009270, BC042781, BC056361 NM_009270, BC042781, BC056361 NM_009270, BC042781, BC056361 |
20775 |
31 |
squalene monooxygenase activity squalene monooxygenase activity endoplasmic reticulum cellular aromatic compound metabolic process cholesterol metabolic process cholesterol metabolic process response to organic substance membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process oxidoreductase activity regulation of cell population proliferation intracellular membrane-bounded organelle flavin adenine dinucleotide binding FAD binding lipid droplet formation |
00100 01100 |
| TC1700001622.mm.2 |
|
|
|
|
NM_007634, NR_039596, BC037662 NM_007634, NR_039596, BC037662 NM_007634, NR_039596, BC037662 |
|
|
regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex re-entry into mitotic cell cycle placenta development nucleus nucleus cytoplasm centrosome centrosome centriole cytoskeleton cell cycle negative regulation of centrosome duplication negative regulation of centrosome duplication cyclin-dependent protein serine/threonine kinase regulator activity protein ubiquitination SCF ubiquitin ligase complex cell junction SCF-dependent proteasomal ubiquitin-dependent protein catabolic process mitotic cell cycle phase transition cell division regulation of cell cycle |
|
| TC0300002955.mm.2 |
Hadh |
hydroxyacyl-Coenzyme A dehydrogenase |
3 |
-131233419 |
NM_008212, BC064712 NM_008212, BC064712 |
15107 |
40 |
3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity protein binding nucleoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation response to activity oxidoreductase activity response to drug identical protein binding negative regulation of insulin secretion regulation of insulin secretion NAD+ binding positive regulation of cold-induced thermogenesis |
00062 00071 00280 00310 00380 00650 01100 |
| TC0200001748.mm.2 |
Knstrn |
kinetochore-localized astrin/SPAG5 binding |
2 |
118814002 |
NM_026412, BC031709 NM_026412, BC031709 |
51944 |
22 |
mitotic sister chromatid segregation mitotic sister chromatid segregation microtubule cytoskeleton organization chromosome, centromeric region kinetochore kinetochore ruffle protein binding nucleus chromosome cytoplasm cytoskeleton microtubule plasma membrane cell cycle spindle organization spindle organization chromosome segregation cell migration centriolar satellite centriolar satellite microtubule plus-end microtubule plus-end protein homodimerization activity microtubule plus-end binding cell division regulation of attachment of spindle microtubules to kinetochore regulation of attachment of spindle microtubules to kinetochore cellular response to epidermal growth factor stimulus mitotic spindle mitotic spindle |
|
| TC1100001047.mm.2 |
Cluh |
clustered mitochondria (cluA/CLU1) homolog |
11 |
74649503 |
NM_001081158, BC072573 NM_001081158, BC072573 |
74148 |
19 |
mRNA binding mRNA binding cytoplasm cytoplasm mitochondrion organization intracellular distribution of mitochondria intracellular distribution of mitochondria |
|
| TC1300001190.mm.2 |
Dimt1 |
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae) |
13 |
106947128 |
NM_025447, BC019799 NM_025447, BC019799 |
66254 |
18 |
rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity rRNA (adenine-N6,N6-)-dimethyltransferase activity RNA binding nucleus nucleoplasm nucleolus mitochondrial matrix cytosol rRNA processing methyltransferase activity rRNA methyltransferase activity transferase activity rRNA methylation rRNA methylation methylation 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity positive regulation of rRNA processing |
|
| TC0500003090.mm.2 |
Mlec |
malectin |
5 |
-115142980 |
NM_175403, BC035300, BC058245 NM_175403, BC035300, BC058245 NM_175403, BC035300, BC058245 |
109154 |
27 |
endoplasmic reticulum carbohydrate metabolic process membrane integral component of membrane enzyme binding carbohydrate binding |
|
| TC1900000152.mm.2 |
Wdr74 |
WD repeat domain 74 |
19 |
8735838 |
NM_134139, BC019968, BC024478 NM_134139, BC019968, BC024478 NM_134139, BC019968, BC024478 |
107071 |
21 |
nuclear exosome (RNase complex) blastocyst formation molecular_function nucleus nucleus nucleoplasm nucleolus nucleolus rRNA processing RNA metabolic process preribosome, large subunit precursor ribosomal large subunit biogenesis ribosomal large subunit biogenesis |
|
| TC1200001605.mm.2 |
Pik3cg |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma |
12 |
-32173396, -32173396 |
NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246 NM_001146200, NM_001146201, NM_020272, BC051246 |
30955 |
302 |
nucleotide binding angiogenesis regulation of protein phosphorylation immune system process positive regulation of acute inflammatory response sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway protein serine/threonine kinase activity protein binding ATP binding cytoplasm cytoplasm cytosol cytosol plasma membrane plasma membrane phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex, class IA phosphatidylinositol 3-kinase complex, class IB phosphatidylinositol 3-kinase complex, class IB protein phosphorylation endocytosis chemotaxis inflammatory response G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of endothelial cell migration positive regulation of endothelial cell migration negative regulation of triglyceride catabolic process phosphatidylinositol 3-kinase signaling phosphatidylinositol 3-kinase signaling phosphatidylinositol 3-kinase signaling membrane membrane kinase activity 1-phosphatidylinositol-3-kinase activity 1-phosphatidylinositol-3-kinase activity 1-phosphatidylinositol-3-kinase activity phosphorylation cell migration transferase activity secretory granule localization 1-phosphatidylinositol-4-phosphate 3-kinase activity 1-phosphatidylinositol-4-phosphate 3-kinase activity positive regulation of Rac protein signal transduction positive regulation of Rac protein signal transduction phosphatidylinositol-3-phosphate biosynthetic process identical protein binding positive regulation of catalytic activity positive regulation of MAP kinase activity phosphatidylinositol phosphorylation phosphatidylinositol phosphorylation ephrin receptor binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity phosphatidylinositol-mediated signaling positive regulation of protein kinase B signaling phosphatidylinositol kinase activity cellular response to cAMP hepatocyte apoptotic process regulation of calcium ion transmembrane transport negative regulation of fibroblast apoptotic process |
00562 04012 04062 04070 04150 04210 04370 04380 04510 04620 04630 04650 04660 04662 04664 04666 04670 04722 04810 04910 04914 04930 04960 04973 05100 05142 05145 05146 05160 05200 05210 05211 05212 05213 05214 05215 05218 05220 05221 05222 05223 |
| TC1900000184.mm.2 |
Rab3il1 |
RAB3A interacting protein (rabin3)-like 1 |
19 |
10018193, 10001668, 10018193, 10018193, 10018250, 10001724, 10015046, 10018250 |
NM_144538, BC020147 NM_144538, BC020147 |
74760 |
19 |
guanyl-nucleotide exchange factor activity exocytosis protein transport kinase binding identical protein binding Golgi to plasma membrane transport vesicle |
|
| TC1000002453.mm.2 |
Pdxk |
pyridoxal (pyridoxine, vitamin B6) kinase |
10 |
-78436746 |
NM_172134, BC027745 NM_172134, BC027745 |
216134 |
31 |
nucleotide binding magnesium ion binding ATP binding nucleoplasm cytoplasm cytosol zinc ion binding pyridoxal kinase activity pyridoxal kinase activity pyridoxal 5'-phosphate salvage pyridoxal 5'-phosphate salvage kinase activity phosphorylation transferase activity pyridoxal phosphate binding potassium ion binding sodium ion binding lithium ion binding small molecule binding protein homodimerization activity pyridoxal phosphate biosynthetic process negative regulation of apoptotic process metal ion binding pyridoxal binding |
00750 01100 |
| TC0300002500.mm.2 |
H3c15 |
H3 clustered histone 15 |
3 |
96246699, -96238478 |
NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 NM_054045, BC015270, BC132488, BC132490, BC156965 |
97114 |
5 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
05322 |
| TC0300003216.mm.2 |
|
|
|
|
NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 NM_178216, BC094041, BC132488, BC132490, BC156965 |
|
|
negative regulation of transcription by RNA polymerase II nuclear chromosome nucleosome chromatin binding nucleus nucleus nucleosome assembly DNA replication-dependent nucleosome assembly protein-containing complex regulation of gene silencing |
|
| TC0500001734.mm.2 |
Daglb |
diacylglycerol lipase, beta |
5 |
143464492 |
NM_144915, BC016105 NM_144915, BC016105 |
231871 |
29 |
prostaglandin biosynthetic process triglyceride lipase activity nucleoplasm plasma membrane lipid metabolic process icosanoid metabolic process G protein-coupled glutamate receptor signaling pathway neuroblast proliferation positive regulation of triglyceride catabolic process membrane integral component of membrane lipid catabolic process lipase activity lipase activity hydrolase activity arachidonic acid metabolic process arachidonic acid metabolic process arachidonic acid metabolic process neurogenesis neurogenesis neurotransmitter biosynthetic process neurotransmitter biosynthetic process postsynaptic membrane metal ion binding regulation of inflammatory response endocannabinoid signaling pathway retrograde trans-synaptic signaling by endocannabinoid |
|
| TC1100000582.mm.2 |
Cdkn2aipnl |
CDKN2A interacting protein N-terminal like |
11 |
51967630 |
NM_029976, BC116362, BC116363 NM_029976, BC116362, BC116363 NM_029976, BC116362, BC116363 |
52626 |
20 |
molecular_function nucleoplasm nucleolus |
|
| TC0200004811.mm.2 |
Cd93 |
CD93 antigen |
2 |
-148436650 |
NM_010740, BC156937, CD93 NM_010740, BC156937, CD93 NM_010740, BC156937, CD93 |
17064 |
42 |
complement component C1q complex binding calcium ion binding plasma membrane plasma membrane cell adhesion cell surface membrane integral component of membrane carbohydrate binding cytoplasmic vesicle cell-cell adhesion cell-cell adhesion |
|
| TC0300001856.mm.2 |
Ccna2 |
cyclin A2 |
3 |
-36564864 |
NM_009828, BC052730 NM_009828, BC052730 |
12428 |
199 |
regulation of cyclin-dependent protein serine/threonine kinase activity G2/M transition of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex female pronucleus male pronucleus protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm cytosol regulation of DNA replication cell cycle cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein serine/threonine kinase regulator activity histone phosphorylation protein kinase binding protein kinase binding protein domain specific binding mitotic cell cycle phase transition cell cycle G1/S phase transition positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of fibroblast proliferation cell division cyclin A2-CDK2 complex cyclin A2-CDK2 complex cyclin A2-CDK2 complex |
04110 04914 |
| TC0X00002993.mm.2 |
Timm8a1 |
translocase of inner mitochondrial membrane 8A1 |
X |
11609223, -134537255 |
NM_013898, BC004796, BC094631 NM_013898, BC004796, BC094631 NM_013898, BC004796, BC094631 |
30058 |
26 |
mitochondrion mitochondrion mitochondrial inner membrane mitochondrial intermembrane space protein targeting to mitochondrion zinc ion binding protein transport membrane identical protein binding metal ion binding chaperone-mediated protein transport |
|
| TC1000002341.mm.2 |
Cdk1 |
cyclin-dependent kinase 1 |
10 |
-69335145 |
NM_007659, BC024396 NM_007659, BC024396 |
12534 |
223 |
G2/M transition of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex chromatin binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm mitochondrion mitochondrial matrix mitochondrial matrix centrosome cytosol cytoskeleton spindle microtubule protein phosphorylation protein phosphorylation protein phosphorylation apoptotic process cell cycle mitotic G2 DNA damage checkpoint mitotic G2 DNA damage checkpoint cell aging cell population proliferation RNA polymerase II CTD heptapeptide repeat kinase activity RNA polymerase II CTD heptapeptide repeat kinase activity response to organonitrogen compound positive regulation of gene expression negative regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation chromosome condensation cyclin binding midbody Hsp70 protein binding animal organ regeneration protein localization to kinetochore histone kinase activity positive regulation of protein import into nucleus regulation of circadian rhythm negative regulation of apoptotic process mitotic cell cycle phase transition response to ethanol positive regulation of DNA replication positive regulation of mitotic cell cycle rhythmic process cell division positive regulation of cardiac muscle cell proliferation protein-containing complex assembly mitotic spindle Golgi disassembly cyclin B1-CDK1 complex cyclin-dependent protein kinase activity positive regulation of protein localization to nucleus positive regulation of mitochondrial ATP synthesis coupled electron transport |
04110 04114 04115 04540 04914 |
| TC1000002264.mm.2 |
Ddx21 |
DExD box helicase 21 |
10 |
-62580246 |
NM_019553, BC043655, BC059237 NM_019553, BC043655, BC059237 NM_019553, BC043655, BC059237 |
56200 |
47 |
nucleotide binding immune system process positive regulation of myeloid dendritic cell cytokine production nucleic acid binding RNA binding RNA binding RNA helicase activity RNA helicase activity RNA helicase activity double-stranded RNA binding helicase activity protein binding ATP binding nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus cytoplasm mitochondrion cytosol rRNA processing transcription by RNA polymerase II response to virus hydrolase activity rRNA binding snoRNA binding miRNA binding identical protein binding positive regulation of I-kappaB kinase/NF-kappaB signaling response to exogenous dsRNA innate immune response defense response to virus R-loop disassembly 7SK snRNA binding |
|
| TC1800000265.mm.2 |
Wdr36 |
WD repeat domain 36 |
18 |
32837224, 32837224, 32837224 |
NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453 NM_001110015, NM_001110016, NM_144863, BC094453 |
225348 |
24 |
retina homeostasis nucleolus rRNA processing regulation of axon extension small-subunit processome Pwp2p-containing subcomplex of 90S preribosome |
03008 |
| TC1700001003.mm.2 |
Uhrf1 |
ubiquitin-like, containing PHD and RING finger domains, 1 |
17 |
56303336, 56304312 |
NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 NM_001111078, NM_001111079, NM_001111080, NM_010931, BC022167 |
18140 |
107 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin euchromatin heterochromatin heterochromatin cis-regulatory region sequence-specific DNA binding DNA binding ubiquitin-protein transferase activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm replication fork replication fork plasma membrane DNA repair chromatin organization ubiquitin-dependent protein catabolic process cellular response to DNA damage stimulus cell cycle zinc ion binding methyl-CpG binding maintenance of DNA methylation maintenance of DNA methylation maintenance of DNA methylation histone monoubiquitination histone monoubiquitination nuclear matrix protein ubiquitination histone ubiquitination transferase activity cytoplasmic vesicle nucleosomal histone binding positive regulation of cellular protein metabolic process methylated histone binding methylated histone binding histone binding identical protein binding hemi-methylated DNA-binding hemi-methylated DNA-binding metal ion binding regulation of epithelial cell proliferation protein autoubiquitination protein autoubiquitination ubiquitin protein ligase activity ubiquitin protein ligase activity |
|
| TC1400002836.mm.2 |
Dok2 |
docking protein 2 |
14 |
70774380 |
NM_010071, BC004590 NM_010071, BC004590 |
13449 |
54 |
transmembrane receptor protein tyrosine kinase adaptor activity protein binding transmembrane receptor protein tyrosine kinase signaling pathway Ras protein signal transduction negative regulation of MAPK cascade |
|
| TC0200001776.mm.2 |
Nusap1 |
nucleolar and spindle associated protein 1 |
2 |
119618297 |
NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392 NM_001042652, NM_133851, BC004787, BC100392 |
108907 |
31 |
mitotic sister chromatid segregation microtubule cytoskeleton organization mitotic cytokinesis mitotic cytokinesis DNA binding nucleus chromosome nucleolus nucleolus cytoplasm spindle cytoskeleton microtubule cell cycle mitotic chromosome condensation mitotic chromosome condensation microtubule binding microtubule binding establishment of mitotic spindle localization establishment of mitotic spindle localization positive regulation of mitotic nuclear division cell division mitotic spindle |
|
| TC0100000590.mm.2 |
Atic |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase |
1 |
71557155 |
NM_026195, BC039925 NM_026195, BC039925 |
108147 |
24 |
catalytic activity IMP cyclohydrolase activity IMP cyclohydrolase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity phosphoribosylaminoimidazolecarboxamide formyltransferase activity mitochondrion cytosol cytosol plasma membrane purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process 'de novo' IMP biosynthetic process metabolic process nucleoside metabolic process ribonucleotide metabolic process transferase activity hydrolase activity protein homodimerization activity dihydrofolate metabolic process tetrahydrofolate biosynthetic process cellular response to interleukin-7 |
00230 00670 01100 |
| TC1500001940.mm.2 |
Cenpm |
centromere protein M |
15 |
-82233775, -82233775 |
NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160 NM_001080158, NM_025639, NM_178269, BC009160 |
66570 |
19 |
chromosome, centromeric region kinetochore molecular_function nucleus chromosome cytoplasm cytosol biological_process |
|
| TC1300001574.mm.2 |
H2ac12 |
H2A clustered histone 12 |
13 |
-22035121 |
NM_175659, BC139479, BC146008 NM_175659, BC139479, BC146008 NM_175659, BC139479, BC146008 |
319168 |
11 |
nucleosome DNA binding nucleus chromosome chromatin silencing protein heterodimerization activity |
05322 |
| TC1300000972.mm.2 |
Mef2c |
myocyte enhancer factor 2C |
13 |
83504033, 83573606, 83524742, 83523655 |
NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 NM_001170537, NM_025282, BC026841, BC037731, BC057650 |
17260 |
401 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II MAPK cascade MAPK cascade MAPK cascade transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development osteoblast differentiation osteoblast differentiation neuron migration B cell homeostasis heart looping endochondral ossification endochondral ossification blood vessel remodeling chondrocyte differentiation germinal center formation regulation of germinal center formation primary heart field specification secondary heart field specification outflow tract morphogenesis sinoatrial valve morphogenesis cardiac ventricle formation cardiac ventricle formation DNA binding DNA binding minor groove of adenine-thymine-rich DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II apoptotic process humoral immune response multicellular organism development nervous system development heart development heart development skeletal muscle tissue development muscle cell fate determination learning or memory positive regulation of cardiac muscle hypertrophy positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of alkaline phosphatase activity neural crest cell differentiation cardiac muscle hypertrophy in response to stress nuclear speck sarcomere cell differentiation neuron differentiation platelet formation monocyte differentiation negative regulation of ossification melanocyte differentiation positive regulation of bone mineralization positive regulation of B cell proliferation protein-containing complex activating transcription factor binding cellular response to drug skeletal muscle cell differentiation skeletal muscle cell differentiation cellular response to trichostatin A B cell proliferation histone deacetylase binding histone deacetylase binding intracellular membrane-bounded organelle regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of blood vessel endothelial cell migration sequence-specific DNA binding cell fate commitment regulation of megakaryocyte differentiation positive regulation of myoblast differentiation positive regulation of neuron differentiation positive regulation of osteoblast differentiation positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of neurotransmitter secretion protein heterodimerization activity protein dimerization activity regulation of synaptic plasticity positive regulation of skeletal muscle tissue development neuron development cell morphogenesis involved in neuron differentiation embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis negative regulation of epithelial cell proliferation B cell receptor signaling pathway smooth muscle cell differentiation regulation of synapse assembly regulation of synaptic transmission, glutamatergic cardiac muscle cell differentiation cardiac muscle cell differentiation ventricular cardiac muscle cell differentiation roof of mouth development regulation of synaptic activity positive regulation of cardiac muscle cell proliferation excitatory postsynaptic potential transdifferentiation regulation of sarcomere organization cartilage morphogenesis regulation of dendritic spine development renal tubule morphogenesis cellular response to lipopolysaccharide cellular response to calcium ion cellular response to retinoic acid cellular response to growth factor stimulus cellular response to parathyroid hormone stimulus cellular response to fluid shear stress cellular response to transforming growth factor beta stimulus HMG box domain binding positive regulation of cell proliferation in bone marrow glomerulus morphogenesis nephron tubule epithelial cell differentiation negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration negative regulation of vascular endothelial cell proliferation sequence-specific double-stranded DNA binding positive regulation of macrophage apoptotic process regulation of NMDA receptor activity regulation of AMPA receptor activity positive regulation of cardiac muscle cell differentiation positive regulation of cardiac muscle cell differentiation positive regulation of behavioral fear response epithelial cell proliferation involved in renal tubule morphogenesis positive regulation of skeletal muscle cell differentiation |
04010 |
| TC0200001045.mm.2 |
Itga6 |
integrin alpha 6 |
2 |
71786938 |
NM_001277970, NM_008397, BC058095 NM_001277970, NM_008397, BC058095 NM_001277970, NM_008397, BC058095 |
16403 |
274 |
integrin binding protein binding basement membrane plasma membrane plasma membrane adherens junction cell adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin complex external side of plasma membrane basal plasma membrane cell surface cell surface positive regulation of cell-substrate adhesion positive regulation of neuron projection development membrane integral component of membrane basolateral plasma membrane positive regulation of cell-cell adhesion hemidesmosome filopodium positive regulation of cell migration cell-substrate adhesion cellular response to extracellular stimulus insulin-like growth factor I binding cell adhesion mediated by integrin integrin alpha6-beta4 complex nail development neuregulin binding positive regulation of phosphorylation odontogenesis of dentin-containing tooth positive regulation of apoptotic process laminin binding positive regulation of GTPase activity skin morphogenesis protein-containing complex binding basal part of cell positive regulation of transcription by RNA polymerase II filopodium assembly metal ion binding brown fat cell differentiation leukocyte migration leukocyte migration cell-cell adhesion negative regulation of extrinsic apoptotic signaling pathway |
04510 04512 04514 04640 04810 05145 05200 05222 05410 05412 05414 |
| TC1300000191.mm.2 |
H2bc12 |
H2B clustered histone 12 |
13 |
22035820 |
NM_175665, BC147143, BC147144 NM_175665, BC147143, BC147144 NM_175665, BC147143, BC147144 |
319184 |
9 |
nucleosome innate immune response in mucosa DNA binding extracellular space nucleus nucleoplasm nucleoplasm chromosome cytosol nucleosome assembly antibacterial humoral response killing of cells of other organism protein heterodimerization activity defense response to Gram-negative bacterium defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide |
05322 |
| TC1300001634.mm.2 |
H2ac8 |
H2A clustered histone 8 |
13 |
-23570662 |
NM_178187, BC058544, BC076498 NM_178187, BC058544, BC076498 NM_178187, BC058544, BC076498 |
319166 |
12 |
DNA binding nucleus chromatin silencing enzyme binding |
05322 |
| TC0X00003361.mm.2 |
Prps2 |
phosphoribosyl pyrophosphate synthetase 2 |
X |
-167346319 |
NM_026662, BC024942 NM_026662, BC024942 |
110639 |
23 |
nucleotide binding magnesium ion binding ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding ATP binding cytoplasm 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process purine nucleotide biosynthetic process AMP biosynthetic process nucleoside metabolic process ribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process AMP binding kinase activity phosphorylation transferase activity GDP binding ribose phosphate metabolic process carbohydrate binding protein-containing complex identical protein binding ADP binding cellular biosynthetic process metal ion binding |
00030 00230 01100 |
| TC1600002082.mm.2 |
Gart |
phosphoribosylglycinamide formyltransferase |
16 |
-91621396 |
NM_010256, BC070465 NM_010256, BC070465 |
14450 |
40 |
nucleotide binding catalytic activity phosphoribosylamine-glycine ligase activity phosphoribosylamine-glycine ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylformylglycinamidine cyclo-ligase activity phosphoribosylglycinamide formyltransferase activity ATP binding cytosol purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process glycine metabolic process metabolic process biosynthetic process purine nucleobase biosynthetic process ribonucleoside monophosphate biosynthetic process response to organic substance response to inorganic substance transferase activity hydroxymethyl-, formyl- and related transferase activity ligase activity adenine biosynthetic process tetrahydrofolate biosynthetic process metal ion binding |
00230 00670 01100 |
| TC1500001127.mm.2 |
|
|
|
|
NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 NM_001039129, NM_010447, NR_002885, NR_104427, BC080675, BC083136, BC089340, BC092395, NR_002883 |
|
|
alternative mRNA splicing, via spliceosome nucleic acid binding RNA binding nucleus nucleoplasm spliceosomal complex cytoplasm mRNA processing RNA splicing mRNA transport ribonucleoprotein complex |
|
| TC0800000126.mm.2 |
Tfdp1 |
transcription factor Dp 1 |
8 |
13338803, 13338750 |
NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344 NM_009361, BC132567, BC132569, BC145344 |
21781 |
62 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm cytoplasm cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II transcription by RNA polymerase II cell cycle transcription factor binding epidermis development protein domain specific binding anoikis positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of DNA-binding transcription factor activity regulation of cell cycle negative regulation of fat cell proliferation RNA polymerase II transcription regulator complex positive regulation of G1/S transition of mitotic cell cycle regulation of DNA biosynthetic process |
04110 04350 |
| TC1100000983.mm.2 |
Pimreg |
PICALM interacting mitotic regulator |
11 |
72042501 |
NM_144526, BC020115, BC029115 NM_144526, BC020115, BC029115 NM_144526, BC020115, BC029115 |
109212 |
18 |
molecular_function nucleus nucleoplasm nucleolus cell cycle cell division |
|
| TC1300002543.mm.2 |
Ccnb1 |
cyclin B1 |
13 |
-100778738 |
NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238 NM_172301, BC011478, BC080202, BC085238 |
268697 |
210 |
regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex spindle pole condensed nuclear chromosome outer kinetochore oocyte maturation in utero embryonic development negative regulation of protein phosphorylation patched binding protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm mitochondrial matrix mitochondrial matrix mitochondrial matrix centrosome centrosome cytosol cytoskeleton protein phosphorylation cell cycle mitotic spindle organization mitotic metaphase plate congression mitotic metaphase plate congression negative regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle membrane cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding positive regulation of mRNA 3'-end processing positive regulation of histone phosphorylation ubiquitin-like protein ligase binding mitotic cell cycle phase transition protein-containing complex binding positive regulation of cell cycle positive regulation of mitotic cell cycle positive regulation of fibroblast proliferation cell division positive regulation of attachment of spindle microtubules to kinetochore positive regulation of cardiac muscle cell proliferation regulation of chromosome condensation cyclin-dependent protein serine/threonine kinase activator activity protein-containing complex assembly regulation of mitotic cell cycle spindle assembly checkpoint cyclin B1-CDK1 complex cyclin B1-CDK1 complex positive regulation of mitochondrial ATP synthesis coupled electron transport histone H3-S10 phosphorylation involved in chromosome condensation |
04110 04114 04115 04914 |
| TC1300000177.mm.2 |
H2bc15 |
H2B clustered histone 15 |
13 |
21754075 |
NM_178201 |
319187 |
4 |
nucleus nucleoplasm cytosol |
05322 |
| TC1800001087.mm.2 |
Tpgs2 |
tubulin polyglutamylase complex subunit 2 |
18 |
-25136038, -25127222, -25136038 |
NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777 NM_001004361, NM_001142697, NM_001142698, BC080777 |
66648 |
19 |
molecular_function cellular_component cytoplasm cytosol cytoskeleton microtubule biological_process protein polyglutamylation protein polyglutamylation |
|
| TC0200000651.mm.2 |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
2 |
36230425 |
NM_008969, BC005573, BC023322 NM_008969, BC005573, BC023322 NM_008969, BC005573, BC023322 |
19224 |
299 |
prostaglandin biosynthetic process prostaglandin biosynthetic process photoreceptor outer segment peroxidase activity prostaglandin-endoperoxide synthase activity nuclear envelope cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process prostaglandin metabolic process inflammatory response response to oxidative stress learning memory regulation of blood pressure negative regulation of norepinephrine secretion membrane oxidoreductase activity sensory perception of pain cyclooxygenase pathway heme binding keratinocyte differentiation negative regulation of epinephrine secretion maintenance of blood-brain barrier regulation of cell population proliferation intracellular membrane-bounded organelle positive regulation of vasoconstriction positive regulation of smooth muscle contraction metal ion binding dioxygenase activity |
00590 01100 |
| TC1600001373.mm.2 |
Tmem41a |
transmembrane protein 41a |
16 |
-21934326 |
NM_025693, NR_037773, BC019770 NM_025693, NR_037773, BC019770 NM_025693, NR_037773, BC019770 |
66664 |
13 |
molecular_function cellular_component biological_process membrane integral component of membrane |
|
| TC1000003152.mm.2 |
Pa2g4 |
proliferation-associated 2G4 |
10 |
-128557765 |
NM_011119, BC046532 NM_011119, BC046532 |
18813 |
52 |
nucleic acid binding transcription corepressor activity RNA binding nucleus nucleolus cytoplasm rRNA processing regulation of translation ubiquitin protein ligase binding negative regulation of apoptotic process positive regulation of cell differentiation negative regulation of transcription, DNA-templated ribonucleoprotein complex |
|
| TC0600002690.mm.2 |
Mcm2 |
minichromosome maintenance complex component 2 |
6 |
-88883473 |
NM_008564, BC055318 NM_008564, BC055318 |
17216 |
82 |
nucleotide binding double-strand break repair via break-induced replication chromatin DNA binding DNA replication origin binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleus nucleoplasm nuclear origin of replication recognition complex chromosome cytoplasm DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA replication initiation nucleosome assembly apoptotic process cell cycle hydrolase activity single-stranded DNA helicase activity enzyme binding histone binding MCM complex MCM complex 3'-5' DNA helicase activity metal ion binding cellular response to interleukin-4 cochlea development mitotic DNA replication initiation negative regulation of DNA helicase activity |
03030 04110 |
| MG-1-pos-10339595_st |
|
|
|
|
|
|
|
|
|
| TC1800001437.mm.2 |
Adrb2 |
adrenergic receptor, beta 2 |
18 |
-62177712 |
NM_007420, BC032883 NM_007420, BC032883 |
11555 |
345 |
amyloid-beta binding G-protein alpha-subunit binding regulation of systemic arterial blood pressure by norepinephrine-epinephrine diet induced thermogenesis norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure regulation of sodium ion transport desensitization of G protein-coupled receptor signaling pathway by arrestin diaphragm contraction positive regulation of the force of heart contraction by epinephrine G protein-coupled receptor activity adrenergic receptor activity beta2-adrenergic receptor activity beta2-adrenergic receptor activity beta2-adrenergic receptor activity protein binding nucleus nucleus cytoplasm endosome Golgi apparatus plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane caveola receptor-mediated endocytosis regulation of smooth muscle contraction signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase binding positive regulation of cell population proliferation associative learning response to cold positive regulation of protein kinase A signaling positive regulation of protein kinase A signaling positive regulation of sodium ion transport potassium channel regulator activity membrane membrane integral component of membrane apical plasma membrane negative regulation of angiogenesis enzyme binding negative regulation of ossification axon dendrite positive regulation of bone mineralization heat generation B2 bradykinin receptor binding positive regulation of ATPase activity neuronal cell body membrane synaptic transmission, glutamatergic ionotropic glutamate receptor binding negative regulation of urine volume negative regulation of multicellular organism growth wound healing sarcolemma identical protein binding protein homodimerization activity positive regulation of apoptotic process dendritic spine intracellular membrane-bounded organelle receptor complex positive regulation of potassium ion transport positive regulation of MAPK cascade protein-containing complex binding bone resorption positive regulation of heart contraction positive regulation of transcription by RNA polymerase II negative regulation of smooth muscle contraction negative regulation of smooth muscle contraction positive regulation of skeletal muscle tissue growth negative regulation of inflammatory response brown fat cell differentiation norepinephrine binding norepinephrine binding protein phosphatase 2A binding regulation of calcium ion transport regulation of sensory perception of pain excitatory postsynaptic potential positive regulation of mini excitatory postsynaptic potential cellular response to hypoxia adrenergic receptor signaling pathway adenylate cyclase-activating adrenergic receptor signaling pathway positive regulation of protein serine/threonine kinase activity negative regulation of platelet aggregation receptor-receptor interaction blood vessel diameter maintenance glutamatergic synapse positive regulation of cold-induced thermogenesis positive regulation of autophagosome maturation positive regulation of lipophagy cellular response to amyloid-beta cellular response to amyloid-beta positive regulation of calcium ion import across plasma membrane regulation of synaptic vesicle exocytosis positive regulation of AMPA receptor activity |
04020 04080 04144 04970 |
| TC1500001750.mm.2 |
Eef1d |
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
15 |
-75894795, -75894795 |
NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 NM_001285429, NM_001285430, NM_001285431, NM_001285432, NM_001285433, NM_001285434, NM_023240, NM_029663, BC079855 |
66656 |
35 |
fibrillar center DNA binding translation elongation factor activity guanyl-nucleotide exchange factor activity nucleus nucleoplasm cytoplasm cytoplasm endoplasmic reticulum cytosol cytosol eukaryotic translation elongation factor 1 complex translation translational elongation mRNA transcription regulation of cell death heat shock protein binding activating transcription factor binding synapse synapse cellular response to ionizing radiation glutamatergic synapse glutamatergic synapse |
|
| TC0200000702.mm.2 |
Nek6 |
NIMA (never in mitosis gene a)-related expressed kinase 6 |
2 |
38511696, 38511875 |
NM_001159631, NM_021606, BC019524 NM_001159631, NM_021606, BC019524 NM_001159631, NM_021606, BC019524 |
59126 |
27 |
nucleotide binding magnesium ion binding transcription corepressor binding protein kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleoplasm cytoplasm cytoplasm centrosome cytosol cytoskeleton protein phosphorylation apoptotic process cell cycle chromosome segregation kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation kinesin binding protein kinase binding regulation of mitotic metaphase/anaphase transition ubiquitin protein ligase binding protein-containing complex activating transcription factor binding centriolar satellite protein autophosphorylation metal ion binding cell division |
|
| TC0900002593.mm.2 |
Ccnb2 |
cyclin B2 |
9 |
-70407688 |
NM_007630, BC008247 NM_007630, BC008247 |
12442 |
54 |
regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex in utero embryonic development protein binding nucleus cytoplasm cytoplasm centrosome centrosome cytosol cell cycle spindle assembly involved in female meiosis I spindle assembly involved in female meiosis I G2/MI transition of meiotic cell cycle G2/MI transition of meiotic cell cycle microtubule cytoskeleton membrane cyclin-dependent protein serine/threonine kinase regulator activity regulation of growth T cell homeostasis mitotic cell cycle phase transition thymus development cell division |
04110 04114 04115 04914 |
| TC1900000748.mm.2 |
Add3 |
adducin 3 (gamma) |
19 |
53140442, 53142755, 53143996 |
NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 NM_001164099, NM_001164100, NM_001164101, NM_001277100, NM_013758, BC037116 |
27360 |
31 |
condensed nuclear chromosome actin binding protein kinase C binding structural constituent of cytoskeleton calmodulin binding cytoplasm cytoskeleton cytoskeleton cytoskeleton plasma membrane brush border cell-cell junction cell cortex postsynaptic density postsynaptic density membrane response to drug positive regulation of vasoconstriction actin filament binding barbed-end actin filament capping |
|
| TC0200002263.mm.2 |
Fkbp1a |
FK506 binding protein 1a |
2 |
151542482 |
NM_008019, BC004671, FK506 NM_008019, BC004671, FK506 NM_008019, BC004671, FK506 |
14225 |
73 |
protein peptidyl-prolyl isomerization protein peptidyl-prolyl isomerization heart morphogenesis peptidyl-prolyl cis-trans isomerase activity peptidyl-prolyl cis-trans isomerase activity transforming growth factor beta receptor binding protein binding FK506 binding FK506 binding cytoplasm cytoplasm cytosol muscle contraction SMAD protein complex assembly membrane membrane sarcoplasmic reticulum isomerase activity cytokine-mediated signaling pathway enzyme binding Z disc Hsp70 protein binding response to caffeine positive regulation of protein ubiquitination positive regulation of protein binding negative regulation of phosphoprotein phosphatase activity regulation of protein localization regulation of activin receptor signaling pathway sarcoplasmic reticulum membrane type I transforming growth factor beta receptor binding T cell proliferation identical protein binding intracellular membrane-bounded organelle axon terminus ion channel binding synapse synapse SMAD binding activin binding regulation of immune response release of sequestered calcium ion into cytosol release of sequestered calcium ion into cytosol ventricular cardiac muscle tissue morphogenesis regulation of ryanodine-sensitive calcium-release channel activity regulation of ryanodine-sensitive calcium-release channel activity heart trabecula formation chaperone-mediated protein folding supramolecular fiber organization negative regulation of transforming growth factor beta1 activation regulation of amyloid precursor protein catabolic process amyloid fibril formation |
|
| TC1000000937.mm.2 |
Chst11 |
carbohydrate sulfotransferase 11 |
10 |
82985496 |
NM_021439, BC137629, BC144793 NM_021439, BC137629, BC144793 NM_021439, BC137629, BC144793 |
58250 |
35 |
N-acetylgalactosamine 4-O-sulfotransferase activity in utero embryonic development chondrocyte development Golgi apparatus carbohydrate metabolic process respiratory gaseous exchange by respiratory system sulfotransferase activity sulfotransferase activity post-embryonic development membrane integral component of membrane carbohydrate biosynthetic process transferase activity proteoglycan biosynthetic process chondroitin sulfate metabolic process chondroitin sulfate biosynthetic process chondroitin sulfate biosynthetic process chondroitin sulfate biosynthetic process embryonic limb morphogenesis negative regulation of transforming growth factor beta receptor signaling pathway polysaccharide localization post-anal tail morphogenesis regulation of cell population proliferation embryonic digit morphogenesis negative regulation of apoptotic process chondroitin 4-sulfotransferase activity developmental growth embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity cartilage development |
00532 00920 |
| TC0300001378.mm.2 |
Slc39a8 |
solute carrier family 39 (metal ion transporter), member 8 |
3 |
135825789, 135825656, 135825278 |
NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731 NM_001135149, NM_001135150, NM_026228, BC006731 |
67547 |
51 |
iron ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity lysosome lysosomal membrane plasma membrane plasma membrane integral component of plasma membrane transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated protein N-linked glycosylation arginine metabolic process ion transport cobalt ion transport zinc ion transport cellular cadmium ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis cellular zinc ion homeostasis cadmium ion transmembrane transporter activity cadmium ion transmembrane transporter activity cadmium ion transmembrane transporter activity cobalt ion transmembrane transporter activity bicarbonate transmembrane transporter activity anion:cation symporter activity bicarbonate transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane apical plasma membrane metal ion transport cellular manganese ion homeostasis extracellular matrix organization extracellular matrix organization organelle membrane regulation of membrane potential metal ion transmembrane transporter activity transmembrane transport leukocyte adhesion to arterial endothelial cell cadmium ion transmembrane transport cadmium ion transmembrane transport cadmium ion transmembrane transport manganese ion transmembrane transport manganese ion transmembrane transport manganese ion transmembrane transport zinc ion transmembrane transport zinc ion transmembrane transport zinc ion import across plasma membrane zinc ion import across plasma membrane zinc ion import across plasma membrane zinc ion import across plasma membrane selenite:proton symporter activity plasma membrane selenite transport plasma membrane selenite transport iron ion import across plasma membrane iron ion import across plasma membrane zinc:bicarbonate symporter activity cartilage homeostasis mitochondrial manganese ion transmembrane transport |
|
| TC0200000274.mm.2 |
Plxdc2 |
plexin domain containing 2 |
2 |
16356303 |
NM_026162, BC057881 NM_026162, BC057881 |
67448 |
29 |
plasma membrane membrane integral component of membrane collagen-containing extracellular matrix |
|
| TC1500001657.mm.2 |
Ndrg1 |
N-myc downstream regulated gene 1 |
15 |
-66929317 |
NM_008681, BC015282, BC071235, BC141246, BC171968 NM_008681, BC015282, BC071235, BC141246, BC171968 NM_008681, BC015282, BC071235, BC141246, BC171968 NM_008681, BC015282, BC071235, BC141246, BC171968 NM_008681, BC015282, BC071235, BC141246, BC171968 |
17988 |
82 |
nucleus cytoplasm cytoplasm cytoplasm centrosome cytosol cytoskeleton microtubule plasma membrane adherens junction signal transduction microtubule binding negative regulation of cell population proliferation microtubule cytoskeleton membrane small GTPase binding peripheral nervous system myelin maintenance regulation of cell population proliferation gamma-tubulin binding myelin sheath cadherin binding mast cell activation perinuclear region of cytoplasm recycling endosome membrane glutamatergic synapse postsynapse organization |
|
| TC0200004568.mm.2 |
Bub1 |
BUB1, mitotic checkpoint serine/threonine kinase |
2 |
-127800199 |
NM_001113179, NM_009772, BC029116 NM_001113179, NM_009772, BC029116 NM_001113179, NM_009772, BC029116 |
12235 |
63 |
nucleotide binding chromosome, centromeric region kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed chromosome, centromeric region condensed nuclear chromosome outer kinetochore protein kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleoplasm chromosome cytosol protein phosphorylation apoptotic process cell cycle chromosome segregation regulation of sister chromatid cohesion mitotic spindle assembly checkpoint kinase activity phosphorylation transferase activity intracellular membrane-bounded organelle cell division meiotic sister chromatid cohesion, centromeric regulation of chromosome segregation mitotic spindle checkpoint positive regulation of intrinsic apoptotic signaling pathway |
04110 04114 04914 |
| TC1400001665.mm.2 |
|
|
|
|
NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996 NM_153547, NR_028523, NR_104298, BC037996 |
|
|
nucleotide binding molecular_function protein binding GTP binding GTP binding cellular_component nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus biological_process cell population proliferation nuclear body stem cell division stem cell population maintenance midbody positive regulation of telomere maintenance positive regulation of protein sumoylation regulation of cell population proliferation mRNA 5'-UTR binding positive regulation of pri-miRNA transcription by RNA polymerase II positive regulation of protein localization to chromosome, telomeric region |
|
| TC1100001592.mm.2 |
Igfbp4 |
insulin-like growth factor binding protein 4 |
11 |
99041243 |
NM_010517, BC019836 NM_010517, BC019836 |
16010 |
101 |
regulation of cell growth protein binding insulin-like growth factor binding extracellular region extracellular space extracellular space extracellular space regulation of glucose metabolic process growth factor binding insulin-like growth factor I binding insulin-like growth factor II binding regulation of growth positive regulation of MAPK cascade regulation of insulin-like growth factor receptor signaling pathway positive regulation of insulin-like growth factor receptor signaling pathway type B pancreatic cell proliferation |
|
| TC0400001129.mm.2 |
Ndc1 |
NDC1 transmembrane nucleoporin |
4 |
107368046 |
NM_028355, BC021337 NM_028355, BC021337 |
72787 |
28 |
nucleus nuclear pore nuclear pore cytoplasm plasma membrane nuclear pore organization homologous chromosome pairing at meiosis spermatogenesis protein transport actin cytoskeleton membrane integral component of membrane structural constituent of nuclear pore protein-macromolecule adaptor activity nuclear membrane mRNA transport nuclear pore complex assembly nuclear pore localization nuclear pore transmembrane ring |
03013 |
| TC0300000491.mm.2 |
P2ry1 |
purinergic receptor P2Y, G-protein coupled 1 |
3 |
61002784 |
NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635 NM_001282016, NM_008772, BC138634, BC138635 |
18441 |
114 |
nucleotide binding G protein-coupled ADP receptor activity positive regulation of protein phosphorylation G protein-coupled adenosine receptor signaling pathway G protein-coupled receptor activity ATP binding mitochondrion plasma membrane plasma membrane integral component of plasma membrane cilium signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration glial cell migration regulation of cell shape response to mechanical stimulus regulation of signaling receptor activity negative regulation of norepinephrine secretion postsynaptic density membrane integral component of membrane basolateral plasma membrane apical plasma membrane sensory perception of pain signal transduction involved in regulation of gene expression platelet activation dendrite A1 adenosine receptor binding positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor signaling pathway eating behavior positive regulation of ion transport positive regulation of ion transport ADP binding cell body G protein-coupled purinergic nucleotide receptor activity G protein-coupled ATP receptor activity postsynaptic membrane positive regulation of transcription by RNA polymerase II positive regulation of hormone secretion protein heterodimerization activity negative regulation of binding positive regulation of penile erection positive regulation of ERK1 and ERK2 cascade cellular response to organic cyclic compound cellular response to purine-containing compound protein localization to plasma membrane relaxation of muscle scaffold protein binding blood vessel diameter maintenance glutamatergic synapse integral component of presynaptic active zone membrane regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic vesicle exocytosis |
04080 |
| TC0800002878.mm.2 |
Nob1 |
NIN1/RPN12 binding protein 1 homolog |
8 |
-107412488 |
NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993 NM_026277, BC103793, BC117992, BC117993 |
67619 |
23 |
cleavage involved in rRNA processing nuclease activity endonuclease activity endoribonuclease activity endoribonuclease activity nucleus nucleolus cytoplasm visual perception hydrolase activity maturation of SSU-rRNA maturation of SSU-rRNA preribosome, small subunit precursor ribosomal small subunit biogenesis metal ion binding |
03008 |
| TC0900001414.mm.2 |
Impdh2 |
inosine monophosphate dehydrogenase 2 |
9 |
108560435 |
NM_011830, BC010314, BC052671 NM_011830, BC010314, BC052671 NM_011830, BC010314, BC052671 |
23918 |
38 |
nucleotide binding DNA binding RNA binding catalytic activity IMP dehydrogenase activity IMP dehydrogenase activity IMP dehydrogenase activity nucleus cytoplasm cytoplasm cytosol purine nucleotide biosynthetic process purine nucleotide biosynthetic process GMP biosynthetic process GTP biosynthetic process circadian rhythm oxidoreductase activity identical protein binding lymphocyte proliferation metal ion binding cellular response to interleukin-4 |
00230 00983 01100 |
| TC1100003470.mm.2 |
Prr11 |
proline rich 11 |
11 |
-87089155 |
NM_175563, BC023918 NM_175563, BC023918 |
270906 |
14 |
molecular_function nucleus nucleus cytoplasm cytoplasm cell cycle arrest regulation of cell cycle |
|
| TC1600001316.mm.2 |
Comt |
catechol-O-methyltransferase |
16 |
-18406881, -18406881 |
NM_001111062, NM_001111063, NM_007744, BC010402 NM_001111062, NM_001111063, NM_007744, BC010402 NM_001111062, NM_001111063, NM_007744, BC010402 NM_001111062, NM_001111063, NM_007744, BC010402 |
12846 |
101 |
magnesium ion binding cytoplasm mitochondrion cytosol catecholamine metabolic process female pregnancy learning short-term memory methyltransferase activity O-methyltransferase activity estrogen metabolic process catechol-containing compound metabolic process membrane membrane integral component of membrane cellular response to phosphate starvation catechol O-methyltransferase activity catechol O-methyltransferase activity catechol O-methyltransferase activity catechol O-methyltransferase activity transferase activity axon axon dendrite dendrite methylation developmental process negative regulation of renal sodium excretion neurotransmitter catabolic process dopamine metabolic process dopamine metabolic process dopamine metabolic process dopamine catabolic process catecholamine catabolic process catecholamine catabolic process dendritic spine intracellular membrane-bounded organelle cell body postsynaptic membrane negative regulation of dopamine metabolic process metal ion binding response to pain multicellular organismal reproductive process negative regulation of smooth muscle cell proliferation positive regulation of homocysteine metabolic process regulation of sensory perception of pain L-dopa O-methyltransferase activity |
00140 00350 01100 |
| TC0100003639.mm.2 |
Adss |
adenylosuccinate synthetase, non muscle |
1 |
-177763177 |
NM_007422, BC139404, BC139417 NM_007422, BC139404, BC139417 NM_007422, BC139404, BC139417 |
11566 |
23 |
nucleotide binding adenylosuccinate synthase activity adenylosuccinate synthase activity adenylosuccinate synthase activity GTP binding cytoplasm mitochondrion cytosol purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process aspartate metabolic process ligase activity 'de novo' AMP biosynthetic process IMP metabolic process IMP metabolic process metal ion binding |
00230 00250 01100 |
| TC1400002057.mm.2 |
Prmt5 |
protein arginine N-methyltransferase 5 |
14 |
-54507181 |
NM_013768, BC023905 NM_013768, BC023905 |
27374 |
104 |
negative regulation of transcription by RNA polymerase II spliceosomal snRNP assembly p53 binding chromatin binding transcription corepressor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm Golgi apparatus cytosol cytosol chromatin organization DNA-templated transcription, termination regulation of transcription, DNA-templated protein methylation methyltransferase activity methyl-CpG binding histone-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity transferase activity peptidyl-arginine methylation methylation circadian regulation of gene expression protein-containing complex methylosome histone arginine methylation histone methyltransferase complex histone methyltransferase complex protein-arginine omega-N symmetric methyltransferase activity peptidyl-arginine N-methylation endothelial cell activation identical protein binding ribonucleoprotein complex binding histone H4-R3 methylation histone methyltransferase activity (H4-R3 specific) regulation of DNA methylation protein-containing complex binding negative regulation of cell differentiation protein heterodimerization activity rhythmic process positive regulation of oligodendrocyte differentiation regulation of ERK1 and ERK2 cascade E-box binding Golgi ribbon formation positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway |
03013 |
| TC1000000240.mm.2 |
Arhgap18 |
Rho GTPase activating protein 18 |
10 |
26772511 |
NM_176837, BC030858 NM_176837, BC030858 |
73910 |
22 |
ruffle GTPase activator activity GTPase activator activity cytoplasm cytoplasm cytosol cytoplasmic microtubule plasma membrane signal transduction small GTPase mediated signal transduction regulation of cell shape nuclear speck regulation of actin filament polymerization regulation of actin filament polymerization regulation of actin cytoskeleton organization regulation of small GTPase mediated signal transduction regulation of small GTPase mediated signal transduction regulation of cell motility |
|
| TC0100001500.mm.2 |
Slc19a2 |
solute carrier family 19 (thiamine transporter), member 2 |
1 |
164249045 |
NM_001276455, NM_054087, BC034659 NM_001276455, NM_054087, BC034659 NM_001276455, NM_054087, BC034659 |
116914 |
26 |
plasma membrane plasma membrane plasma membrane plasma membrane thiamine transmembrane transporter activity thiamine transmembrane transporter activity thiamine transmembrane transporter activity thiamine transmembrane transporter activity thiamine transport thiamine transport membrane integral component of membrane vitamin transport transmembrane transport thiamine transmembrane transport vitamin transmembrane transporter activity |
04977 |
| TC0100003029.mm.2 |
Cxcr4 |
chemokine (C-X-C motif) receptor 4 |
1 |
-128588198 |
NM_009911, BC031665, BC098322 NM_009911, BC031665, BC098322 NM_009911, BC031665, BC098322 |
12767 |
580 |
branching involved in blood vessel morphogenesis ameboidal-type cell migration neuron migration neuron migration kidney development positive regulation of protein phosphorylation epithelial cell development ventricular septum development actin binding G protein-coupled receptor activity chemokine receptor activity protein binding nucleus cytoplasm lysosome endosome early endosome late endosome plasma membrane plasma membrane cell-cell junction chemotaxis immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration germ cell development nervous system development brain development brain development motor neuron axon guidance germ cell migration animal organ morphogenesis external side of plasma membrane external side of plasma membrane cell surface cell surface membrane integral component of membrane cell migration C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling cytokine binding C-C chemokine binding C-C chemokine binding neurogenesis neurogenesis telencephalon cell migration cell junction regulation of cell adhesion regulation of cell migration regulation of cell migration positive regulation of cell migration growth cone cell leading edge cytoplasmic vesicle ubiquitin protein ligase binding myosin light chain binding protein-containing complex positive regulation of vascular wound healing hematopoietic stem cell migration aorta development C-X-C motif chemokine 12 receptor activity CXCL12-activated CXCR4 signaling pathway T cell proliferation identical protein binding regulation of programmed cell death ubiquitin binding myelin maintenance endothelial cell differentiation generation of neurons positive regulation of oligodendrocyte differentiation positive regulation of neurogenesis regulation of viral process regulation of chemotaxis positive regulation of chemotaxis detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain regulation of calcium ion transport cardiac muscle contraction cell chemotaxis endothelial tube morphogenesis neural precursor cell proliferation positive regulation of ERK1 and ERK2 cascade cellular response to cytokine stimulus cellular response to cytokine stimulus positive regulation of calcium ion import positive regulation of cold-induced thermogenesis positive regulation of dendrite extension positive regulation of mesenchymal stem cell migration positive regulation of macrophage migration inhibitory factor signaling pathway |
04060 04062 04144 04360 04670 04672 |
| TC0300002284.mm.2 |
Fcrls |
Fc receptor-like S, scavenger receptor |
3 |
-87250964 |
NM_030707, BC016551 NM_030707, BC016551 |
80891 |
22 |
transmembrane signaling receptor activity integral component of plasma membrane cell surface receptor signaling pathway |
|
| TC1900000508.mm.2 |
Kif20b |
kinesin family member 20B |
19 |
34922357 |
NM_183046, BC151061, BC172148 NM_183046, BC151061, BC172148 NM_183046, BC151061, BC172148 |
240641 |
35 |
nucleotide binding neural tube closure microtubule motor activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm centrosome cytosol cytoskeleton kinesin complex microtubule microtubule-based movement cell cycle regulation of mitotic nuclear division microtubule binding microtubule binding positive regulation of cell population proliferation positive regulation of cell population proliferation ATP-dependent microtubule motor activity, plus-end-directed microtubule cytoskeleton ATPase activity ATPase activity midbody midbody positive regulation of cytokinesis protein localization to microtubule protein homodimerization activity cell projection intercellular bridge perinuclear region of cytoplasm neuron projection morphogenesis WW domain binding spindle midzone cell division regulation of establishment of protein localization contractile ring positive regulation of intracellular protein transport mitotic spindle pole positive regulation of mitotic cytokinetic process mitotic spindle midzone regulation of establishment of cell polarity regulation of establishment of cell polarity regulation of neuron migration positive regulation of neuron migration |
|
| TC1400000940.mm.2 |
Pbk |
PDZ binding kinase |
14 |
65805910 |
NM_023209, BC020099 NM_023209, BC020099 |
52033 |
33 |
nucleotide binding mitotic cell cycle negative regulation of protein phosphorylation protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus protein phosphorylation kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of stress-activated MAPK cascade cellular response to UV negative regulation of inflammatory response |
|
| TC0800002235.mm.2 |
Neil3 |
nei like 3 (E. coli) |
8 |
-53586866 |
NM_146208, BC024921, BC034753 NM_146208, BC024921, BC034753 NM_146208, BC024921, BC034753 |
234258 |
34 |
bubble DNA binding nucleic acid binding DNA binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding catalytic activity DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity nucleus nucleus nucleoplasm chromosome DNA repair base-excision repair base-excision repair base-excision repair nucleotide-excision repair cellular response to DNA damage stimulus metabolic process zinc ion binding hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds lyase activity DNA N-glycosylase activity DNA N-glycosylase activity DNA N-glycosylase activity metal ion binding |
03410 |
| TC1100001155.mm.2 |
Spag5 |
sperm associated antigen 5 |
11 |
78301590 |
NM_017407, BC052672 NM_017407, BC052672 |
54141 |
31 |
mitotic sister chromatid segregation chromosome, centromeric region kinetochore chromosome cytoplasm spindle cytosol cytoskeleton microtubule cell cycle spindle organization chromosome segregation microtubule binding nuclear body positive regulation of intracellular transport centriolar satellite microtubule plus-end establishment of spindle orientation cell division regulation of attachment of spindle microtubules to kinetochore protein localization to centrosome mitotic spindle mitotic spindle regulation of metaphase plate congression mitotic spindle pole positive regulation of spindle assembly |
|
| TC0800000756.mm.2 |
Isyna1 |
myo-inositol 1-phosphate synthase A1 |
8 |
70594480 |
NM_023627, BC003458 NM_023627, BC003458 |
71780 |
23 |
inositol-3-phosphate synthase activity inositol-3-phosphate synthase activity cytoplasm inositol biosynthetic process lipid metabolic process phospholipid biosynthetic process isomerase activity |
00562 01100 |
| MG-1-pos-10343293_st |
|
|
|
|
|
|
|
|
|
| TC0700003831.mm.2 |
P2ry2 |
purinergic receptor P2Y, G-protein coupled 2 |
7 |
-100996567, -100996567 |
NM_008773, BC006613 NM_008773, BC006613 |
18442 |
136 |
G protein-coupled receptor activity ATP binding mitochondrion lysosome early endosome plasma membrane signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of neuron projection development positive regulation of smooth muscle cell migration membrane integral component of membrane basolateral plasma membrane apical plasma membrane sensory perception of pain negative regulation of ossification A1 adenosine receptor binding positive regulation of prostaglandin secretion positive regulation of chemokine production G protein-coupled purinergic nucleotide receptor activity G protein-coupled UTP receptor activity positive regulation of penile erection positive regulation of mucus secretion blood vessel diameter maintenance glutamatergic synapse integral component of presynaptic active zone membrane regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic vesicle exocytosis |
04080 |
| TC0900001173.mm.2 |
Plscr4 |
phospholipid scramblase 4 |
9 |
92457377 |
NM_178711, BC052067 NM_178711, BC052067 |
235527 |
14 |
plasma membrane plasma membrane membrane integral component of membrane plasma membrane phospholipid scrambling phospholipid scramblase activity enzyme binding CD4 receptor binding cellular response to lipopolysaccharide |
|
| TC0X00001322.mm.2 |
Tceal9 |
transcription elongation factor A like 9 |
X |
136245079 |
NM_011712, BC007478 NM_011712, BC007478 |
22381 |
19 |
nucleus WW domain binding WW domain binding |
|
| TC0400001107.mm.2 |
Dhcr24 |
24-dehydrocholesterol reductase |
4 |
106561037 |
NM_053272, BC019797 NM_053272, BC019797 |
74754 |
47 |
delta24(24-1) sterol reductase activity delta24(24-1) sterol reductase activity nucleus cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus cytosol cytoskeleton lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process Ras protein signal transduction protein localization steroid metabolic process steroid metabolic process cholesterol metabolic process negative regulation of cell population proliferation tissue development tissue development membrane membrane integral component of membrane sterol metabolic process sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor enzyme binding male genitalia development plasminogen activation peptide antigen binding amyloid precursor protein catabolic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process skin development delta24-sterol reductase activity flavin adenine dinucleotide binding membrane organization FAD binding |
00100 01100 |
| TC1300000148.mm.2 |
Elmo1 |
engulfment and cell motility 1 |
13 |
20472989, 20090506 |
NM_080288, NM_198093, BC031782, NR_038122 NM_080288, NM_198093, BC031782, NR_038122 NM_080288, NM_198093, BC031782, NR_038122 NM_080288, NM_198093, BC031782, NR_038122 |
140580 |
46 |
guanyl-nucleotide exchange factor activity protein binding cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane phagocytosis phagocytosis, engulfment phagocytosis, engulfment apoptotic process actin filament organization membrane cell migration Rac protein signal transduction Rac protein signal transduction SH3 domain binding actin filament-based process actin cytoskeleton organization actin cytoskeleton organization guanyl-nucleotide exchange factor complex guanyl-nucleotide exchange factor complex guanyl-nucleotide exchange factor complex cell motility cell motility cell motility |
04062 05100 |
| TC0800002529.mm.2 |
Gab1 |
growth factor receptor bound protein 2-associated protein 1 |
8 |
-80764433, -80764430 |
NM_021356, BC007483, BC094659 NM_021356, BC007483, BC094659 NM_021356, BC007483, BC094659 |
14388 |
95 |
activation of MAPK activity angiogenesis protein binding cytoplasm cytosol cell-cell junction response to oxidative stress signal transduction epidermal growth factor receptor signaling pathway activation of JUN kinase activity heart development epidermis development regulation of cell migration actin cytoskeleton reorganization response to hepatocyte growth factor cellular response to vascular endothelial growth factor stimulus vascular endothelial growth factor signaling pathway positive regulation of cell migration by vascular endothelial growth factor signaling pathway positive regulation of MAPK cascade positive regulation of angiogenesis platelet-derived growth factor receptor signaling pathway labyrinthine layer development interleukin-6-mediated signaling pathway endothelial cell chemotaxis to vascular endothelial growth factor |
04012 04722 05100 05211 |
| TC0100001227.mm.2 |
Cyb5r1 |
cytochrome b5 reductase 1 |
1 |
134405780 |
NM_028057, BC016266, BC024618 NM_028057, BC016266, BC024618 NM_028057, BC016266, BC024618 |
72017 |
21 |
cytochrome-b5 reductase activity, acting on NAD(P)H mitochondrion lipid metabolic process steroid biosynthetic process steroid metabolic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity FAD binding |
00520 |
| TC0500003516.mm.2 |
Gna12 |
guanine nucleotide binding protein, alpha 12 |
5 |
-140759943 |
NM_010302, BC111810 NM_010302, BC111810 |
14673 |
87 |
nucleotide binding G protein-coupled receptor binding in utero embryonic development GTPase activity GTPase activity GTPase activity GTP binding cytoplasm heterotrimeric G-protein complex heterotrimeric G-protein complex plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway Rho protein signal transduction Rho protein signal transduction regulation of cell shape regulation of fibroblast migration membrane guanyl nucleotide binding cell differentiation brush border membrane brush border membrane G-protein beta/gamma-subunit complex binding D5 dopamine receptor binding D5 dopamine receptor binding regulation of TOR signaling regulation of TOR signaling regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of proteasomal ubiquitin-dependent protein catabolic process intracellular signal transduction embryonic digit morphogenesis metal ion binding negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration |
04010 04270 04730 04810 |
| TC0400001312.mm.2 |
|
|
|
|
NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876 NM_026932, NR_029469, BC054723, BC062876 |
|
|
nucleus chromosome nucleolus nucleolus rRNA processing preribosome, large subunit precursor nuclear periphery ribosome biogenesis ribosomal large subunit biogenesis |
|
| TC0700001151.mm.2 |
Prc1 |
protein regulator of cytokinesis 1 |
7 |
80294475, 80294450 |
NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475 NM_001285997, NM_001285998, NM_145150, BC005475 |
233406 |
44 |
microtubule cytoskeleton organization cytokinesis microtubule bundle formation nucleus nucleoplasm cytoplasm spindle spindle cytoskeleton microtubule plasma membrane cell cycle microtubule binding positive regulation of cell population proliferation microtubule cytoskeleton kinesin binding protein kinase binding midbody regulation of cytokinesis identical protein binding intercellular bridge mitotic spindle midzone assembly cell division contractile ring mitotic spindle midzone |
|
| TC1000001546.mm.2 |
Cdk4 |
cyclin-dependent kinase 4 |
10 |
127063534 |
NM_009870, BC046336, BC052694 NM_009870, BC046336, BC052694 NM_009870, BC046336, BC052694 |
12567 |
327 |
G1/S transition of mitotic cell cycle nucleotide binding cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex chromatin protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex nucleolus cytoplasm cytosol bicellular tight junction protein phosphorylation protein phosphorylation protein phosphorylation cell cycle signal transduction positive regulation of cell population proliferation RNA polymerase II CTD heptapeptide repeat kinase activity response to organic substance response to lead ion regulation of gene expression positive regulation of G2/M transition of mitotic cell cycle membrane kinase activity phosphorylation mediator complex transferase activity cyclin binding cyclin binding nuclear membrane cellular response to insulin stimulus protein-containing complex response to testosterone regulation of multicellular organism growth regulation of cell population proliferation positive regulation of apoptotic process protein-containing complex binding positive regulation of translation positive regulation of cell size regulation of insulin receptor signaling pathway regulation of lipid biosynthetic process positive regulation of fibroblast proliferation perinuclear region of cytoplasm regulation of lipid catabolic process cell division regulation of cell cycle regulation of cell cycle adipose tissue development negative regulation of cell cycle arrest cellular response to lipopolysaccharide cellular response to interleukin-4 cyclin D2-CDK4 complex cellular response to phorbol 13-acetate 12-myristate cellular response to ionomycin |
04110 04115 04530 04660 05200 05212 05214 05218 05219 05220 05222 05223 |
| TC0600001839.mm.2 |
Asns |
asparagine synthetase |
6 |
-7675164 |
NM_012055, BC005552 NM_012055, BC005552 |
27053 |
29 |
nucleotide binding asparagine synthase (glutamine-hydrolyzing) activity asparagine synthase (glutamine-hydrolyzing) activity ATP binding cytosol cytosol asparagine biosynthetic process asparagine biosynthetic process glutamine metabolic process cellular amino acid biosynthetic process ligase activity cellular response to glucose starvation identical protein binding negative regulation of apoptotic process positive regulation of mitotic cell cycle |
00250 00910 01100 |
| TC1100001051.mm.2 |
Tsr1 |
TSR1 20S rRNA accumulation |
11 |
74898079 |
NM_177325, BC031531 NM_177325, BC031531 |
104662 |
25 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleus preribosome, small subunit precursor U3 snoRNA binding ribosome biogenesis |
|
| TC0X00000169.mm.2 |
Gpr34 |
G protein-coupled receptor 34 |
X |
13632768 |
NM_011823, BC165976 NM_011823, BC165976 |
23890 |
22 |
G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane integral component of membrane G protein-coupled purinergic nucleotide receptor activity |
|
| TC0600002668.mm.2 |
Cnbp |
cellular nucleic acid binding protein |
6 |
-87842614 |
NM_001109745, NM_001109746, NM_013493, BC058723 NM_001109745, NM_001109746, NM_013493, BC058723 NM_001109745, NM_001109746, NM_013493, BC058723 NM_001109745, NM_001109746, NM_013493, BC058723 |
12785 |
53 |
negative regulation of transcription by RNA polymerase II nucleic acid binding DNA binding single-stranded DNA binding single-stranded RNA binding single-stranded RNA binding mRNA binding nucleus cytoplasm endoplasmic reticulum cytosol zinc ion binding positive regulation of cell population proliferation translation regulator activity positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding G-quadruplex DNA binding G-quadruplex DNA formation positive regulation of cytoplasmic translation |
|
| TC0700000487.mm.2 |
Fbl |
fibrillarin |
7 |
28169747 |
NM_007991, BC003813, BC092274 NM_007991, BC003813, BC092274 NM_007991, BC003813, BC092274 |
14113 |
62 |
box C/D RNA 3'-end processing TFIID-class transcription factor complex binding fibrillar center dense fibrillar component granular component RNA binding RNA binding nucleus nucleus nucleoplasm chromosome nucleolus nucleolus nucleolus rRNA processing methyltransferase activity rRNA methyltransferase activity Cajal body Cajal body Cajal body sno(s)RNA metabolic process transferase activity rRNA methylation rRNA methylation box C/D RNP complex small-subunit processome methylation snoRNA localization ATPase binding histone glutamine methylation histone glutamine methylation histone-glutamine methyltransferase activity histone-glutamine methyltransferase activity |
03008 |
| TC0100001058.mm.2 |
Nifk |
nucleolar protein interacting with the FHA domain of MKI67 |
1 |
118321842 |
NM_026472, BC058559 NM_026472, BC058559 |
67949 |
21 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) condensed nuclear chromosome nucleic acid binding RNA binding RNA binding nucleus nucleoplasm chromosome nucleolus nucleolus cytoplasm |
|
| TC0500003169.mm.2 |
Tpcn1 |
two pore channel 1 |
5 |
-120534156 |
NM_145853, BC058951 NM_145853, BC058951 |
252972 |
40 |
ion channel activity voltage-gated ion channel activity voltage-gated calcium channel activity voltage-gated sodium channel activity calcium channel activity lysosome lysosomal membrane lysosomal membrane endosome ion transport calcium ion transport endosome membrane endosome membrane positive regulation of autophagy ligand-gated sodium channel activity membrane integral component of membrane regulation of ion transmembrane transport sodium ion transmembrane transport identical protein binding protein homodimerization activity transmembrane transport calcium ion transmembrane transport NAADP-sensitive calcium-release channel activity NAADP-sensitive calcium-release channel activity phosphatidylinositol-3,5-bisphosphate binding |
|
| TC1900000543.mm.2 |
Cep55 |
centrosomal protein 55 |
19 |
38054983, 38054983, 38055040 |
NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396 NM_001164362, NM_028293, NM_028760, BC031396 |
74107 |
31 |
mitotic cytokinesis mitotic cytokinesis protein binding cytoplasm centrosome cytoskeleton plasma membrane cell cycle regulation of phosphatidylinositol 3-kinase signaling midbody midbody midbody centriolar satellite identical protein binding intercellular bridge establishment of protein localization establishment of protein localization cell division midbody abscission Flemming body cranial skeletal system development |
|
| TC0200001047.mm.2 |
Pdk1 |
pyruvate dehydrogenase kinase, isoenzyme 1 |
2 |
71873223, 71874903 |
NM_172665, BC027196 NM_172665, BC027196 |
228026 |
52 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity pyruvate dehydrogenase (acetyl-transferring) kinase activity ATP binding mitochondrion mitochondrion plasma membrane mitochondrial pyruvate dehydrogenase complex carbohydrate metabolic process glucose metabolic process protein phosphorylation protein phosphorylation cell surface receptor signaling pathway cell population proliferation intrinsic apoptotic signaling pathway in response to oxidative stress regulation of acetyl-CoA biosynthetic process from pyruvate regulation of glucose metabolic process regulation of glucose metabolic process kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation intracellular signal transduction identical protein binding protein-containing complex binding pyruvate dehydrogenase complex hypoxia-inducible factor-1alpha signaling pathway |
04660 04664 04722 05145 05160 |
| TC1300000260.mm.2 |
H2ac4 |
H2A clustered histone 4 |
13 |
23751087 |
NM_175660, BC117110, BC153047 NM_175660, BC117110, BC153047 NM_175660, BC117110, BC153047 |
319172 |
7 |
DNA binding nucleus chromatin silencing |
05322 |
| TC0600001508.mm.2 |
|
|
|
|
NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723 NM_008021, NM_027697, BC065067, BC075723 |
|
|
G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding vasculogenesis liver development molecular_function DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding cellular_component nucleus nucleus DNA repair regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle biological_process positive regulation of cell population proliferation positive regulation of cell population proliferation protein kinase binding negative regulation of stress-activated MAPK cascade regulation of cell population proliferation regulation of cell population proliferation sequence-specific DNA binding negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of Ras protein signal transduction regulation of cell cycle arrest regulation of cell cycle arrest negative regulation of cell aging regulation of reactive oxygen species metabolic process positive regulation of double-strand break repair positive regulation of double-strand break repair |
|
| TC0600001852.mm.2 |
Ica1 |
islet cell autoantigen 1 |
6 |
-8630526, -8630526 |
NM_001252266, NM_010492, BC002030 NM_001252266, NM_010492, BC002030 NM_001252266, NM_010492, BC002030 |
15893 |
37 |
Golgi membrane protein binding cytoplasm Golgi apparatus Golgi stack cytosol cytosol neurotransmitter transport membrane protein domain specific binding cell junction dendrite secretory granule membrane synaptic vesicle membrane cytoplasmic vesicle intracellular membrane-bounded organelle regulation of protein-containing complex assembly synapse regulation of neurotransmitter secretion perinuclear region of cytoplasm regulation of insulin secretion regulation of transport membrane curvature sensor activity |
04940 |
| TC0400003390.mm.2 |
Cdc20 |
cell division cycle 20 |
4 |
-118432900 |
NM_023223, BC003215 NM_023223, BC003215 |
107995 |
81 |
mitotic metaphase protein binding nucleoplasm anaphase-promoting complex anaphase-promoting complex cytoplasm centrosome cytosol cytoskeleton cell cycle mitotic sister chromatid cohesion nervous system development protein C-terminus binding positive regulation of cell population proliferation anaphase-promoting complex binding enzyme binding cell differentiation anaphase-promoting complex-dependent catabolic process anaphase-promoting complex-dependent catabolic process positive regulation of synaptic plasticity protein-containing complex regulation of meiotic nuclear division histone deacetylase binding perinuclear region of cytoplasm regulation of dendrite development cell division positive regulation of synapse maturation mitotic spindle assembly ubiquitin-protein transferase activator activity positive regulation of ubiquitin protein ligase activity positive regulation of anaphase-promoting complex-dependent catabolic process ubiquitin ligase activator activity |
04110 04114 04120 |
| TC1100003771.mm.2 |
Nt5c3b |
5'-nucleotidase, cytosolic IIIB |
11 |
-100429351, -100439552, -100422320 |
NM_001102650, NM_026561, BC015307 NM_001102650, NM_026561, BC015307 NM_001102650, NM_026561, BC015307 |
68106 |
15 |
nucleotide binding magnesium ion binding cytoplasm nucleotide metabolic process hydrolase activity metal ion binding |
|
| TC0400000913.mm.2 |
Mtap |
methylthioadenosine phosphorylase |
4 |
89137369 |
NM_024433, BC003858 NM_024433, BC003858 |
66902 |
37 |
catalytic activity nucleus nucleoplasm cytoplasm cytosol cytosol purine ribonucleoside salvage nucleoside metabolic process transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring pentosyl groups S-methyl-5-thioadenosine phosphorylase activity L-methionine salvage from methylthioadenosine methylation |
00270 01100 |
| TC1800001083.mm.2 |
Slc39a6 |
solute carrier family 39 (metal ion transporter), member 6 |
18 |
-24579880 |
NM_139143, BC054780, BC055012 NM_139143, BC054780, BC055012 NM_139143, BC054780, BC055012 |
106957 |
27 |
zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity endoplasmic reticulum plasma membrane integral component of plasma membrane integral component of plasma membrane ion transport zinc ion transport cellular zinc ion homeostasis cellular zinc ion homeostasis membrane integral component of membrane metal ion transport lamellipodium membrane metal ion transmembrane transporter activity transmembrane transport zinc ion transmembrane transport zinc ion import across plasma membrane zinc ion import across plasma membrane |
|
| TC1200001262.mm.2 |
Adssl1 |
adenylosuccinate synthetase like 1 |
12 |
112620046 |
NM_007421, BC039943 NM_007421, BC039943 |
11565 |
28 |
nucleotide binding GTPase activity adenylosuccinate synthase activity adenylosuccinate synthase activity adenylosuccinate synthase activity protein binding GTP binding cytoplasm cytoplasm cytoplasm purine nucleotide metabolic process purine nucleotide biosynthetic process AMP biosynthetic process aspartate metabolic process purine ribonucleoside monophosphate biosynthetic process membrane ligase activity identical protein binding 'de novo' AMP biosynthetic process IMP metabolic process IMP metabolic process metal ion binding actin filament binding |
00230 00250 01100 |
| TC1200001460.mm.2 |
Lpin1 |
lipin 1 |
12 |
-16535668, -16535668 |
NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462 NM_001130412, NM_015763, NM_172950, BC042462 |
14245 |
127 |
negative regulation of transcription by RNA polymerase II mitochondrial fission RNA polymerase II transcription factor binding transcription coactivator activity transcription coactivator activity protein binding nucleus nucleus transcription regulator complex cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum DNA replication regulation of transcription by RNA polymerase II lipid metabolic process triglyceride mobilization immune response phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity fatty acid catabolic process fatty acid catabolic process membrane hydrolase activity triglyceride biosynthetic process positive regulation of histone deacetylation ruffle organization actin cytoskeleton reorganization negative regulation of myelination nuclear membrane cellular response to insulin stimulus cellular response to insulin stimulus cellular response to insulin stimulus histone deacetylase binding peroxisome proliferator activated receptor binding cellular lipid metabolic process cellular lipid metabolic process fat cell differentiation regulation of fat cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II phosphatidic acid metabolic process positive regulation of cold-induced thermogenesis regulation of phosphatidate phosphatase activity |
|
| TC0800003162.mm.2 |
Nup133 |
nucleoporin 133 |
8 |
-123897122 |
NM_172288, BC023915, BC026845 NM_172288, BC023915, BC026845 NM_172288, BC023915, BC026845 |
234865 |
23 |
chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome outer kinetochore transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear pore nuclear pore nuclear pore chromosome mRNA export from nucleus mRNA export from nucleus protein import into nucleus nuclear pore organization protein transport poly(A)+ mRNA export from nucleus structural constituent of nuclear pore structural constituent of nuclear pore structural constituent of nuclear pore neural tube development neurogenesis nuclear pore outer ring nuclear pore outer ring nuclear membrane paraxial mesoderm development mRNA transport somite development nephron development |
03013 |
| TC0X00001276.mm.2 |
Cenpi |
centromere protein I |
X |
134308083 |
NM_145924, BC030328 NM_145924, BC030328 |
102920 |
14 |
chromosome, centromeric region kinetochore kinetochore molecular_function nucleus chromosome cytosol cytosol biological_process nuclear body nuclear body centromere complex assembly |
|
| TC0800003178.mm.2 |
Egln1 |
egl-9 family hypoxia-inducible factor 1 |
8 |
-124908586 |
NM_053207, BC006903 NM_053207, BC006903 |
112405 |
160 |
response to hypoxia iron ion binding nucleus cytoplasm cytoplasm cytosol cellular iron ion homeostasis ferrous iron binding ferrous iron binding postsynaptic density oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2-oxoglutarate-dependent dioxygenase activity peptidyl-proline hydroxylation to 4-hydroxy-L-proline peptidyl-proline hydroxylation to 4-hydroxy-L-proline enzyme binding L-ascorbic acid binding peptidyl-proline dioxygenase activity peptidyl-proline dioxygenase activity peptidyl-proline 4-dioxygenase activity peptidyl-proline 4-dioxygenase activity oxygen homeostasis positive regulation of apoptotic process negative regulation of DNA-binding transcription factor activity regulation of angiogenesis positive regulation of transcription by RNA polymerase II metal ion binding dioxygenase activity negative regulation of cyclic-nucleotide phosphodiesterase activity cardiac muscle tissue morphogenesis heart trabecula formation ventricular septum morphogenesis labyrinthine layer development cellular response to hypoxia response to nitric oxide glutamatergic synapse glutamatergic synapse regulation of postsynapse organization regulation of postsynapse organization regulation of postsynapse organization regulation of protein catabolic process at postsynapse, modulating synaptic transmission regulation of protein catabolic process at postsynapse, modulating synaptic transmission regulation of protein catabolic process at postsynapse, modulating synaptic transmission regulation of neuron death positive regulation of neuron death negative regulation of CAMKK-AMPK signaling cascade |
05200 05211 |
| TC0200005164.mm.2 |
Sulf2 |
sulfatase 2 |
2 |
-166073898, -166073898 |
NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086 NM_001252578, NM_001252579, NM_028072, BC141086 |
72043 |
66 |
kidney development chondrocyte development glomerular filtration catalytic activity arylsulfatase activity calcium ion binding glycosaminoglycan binding extracellular space endoplasmic reticulum endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane sulfur compound metabolic process N-acetylglucosamine-6-sulfatase activity N-acetylglucosamine-6-sulfatase activity N-acetylglucosamine-6-sulfatase activity sulfuric ester hydrolase activity response to wounding cell surface cell surface positive regulation of vascular endothelial growth factor production positive regulation of vascular endothelial growth factor production esophagus smooth muscle contraction hydrolase activity positive regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway heparan sulfate proteoglycan metabolic process heparan sulfate proteoglycan metabolic process heparan sulfate proteoglycan metabolic process glomerular basement membrane development glomerular basement membrane development glial cell-derived neurotrophic factor receptor signaling pathway negative regulation of fibroblast growth factor receptor signaling pathway negative regulation of fibroblast growth factor receptor signaling pathway metal ion binding embryonic skeletal system development cartilage development bone development innervation positive regulation of canonical Wnt signaling pathway liver regeneration regulation of hepatocyte proliferation |
|
| TC1300000033.mm.2 |
Pitrm1 |
pitrilysin metallepetidase 1 |
13 |
6548156, 6548156 |
NM_145131, BC006917 NM_145131, BC006917 |
69617 |
28 |
catalytic activity metalloendopeptidase activity metalloendopeptidase activity mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix proteolysis peptidase activity metallopeptidase activity zinc ion binding protein processing hydrolase activity metal ion binding |
|
| TC0900000746.mm.2 |
Adpgk |
ADP-dependent glucokinase |
9 |
59291571 |
NM_028121, BC021526 NM_028121, BC021526 |
72141 |
28 |
extracellular region endoplasmic reticulum carbohydrate metabolic process glucose metabolic process glucose metabolic process glycolytic process kinase activity phosphorylation transferase activity phosphotransferase activity, alcohol group as acceptor ADP-specific glucokinase activity ADP-specific glucokinase activity metal ion binding |
00010 01100 |
| TC1000000402.mm.2 |
Cd24a |
CD24a antigen |
10 |
43579168 |
NM_009846, BC075622, CD24a NM_009846, BC075622, CD24a NM_009846, BC075622, CD24a |
12484 |
167 |
response to hypoxia cell activation regulation of cytokine-mediated signaling pathway response to molecule of bacterial origin pre-B cell differentiation immune system process leukocyte migration involved in inflammatory response positive regulation of T cell mediated immune response to tumor cell positive regulation of inflammatory response to antigenic stimulus positive regulation of B cell apoptotic process protein binding plasma membrane plasma membrane cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion cell surface receptor signaling pathway positive regulation of cytosolic calcium ion concentration neuromuscular synaptic transmission neuromuscular synaptic transmission negative regulation of neuroblast proliferation apoptotic mitochondrial changes external side of plasma membrane external side of plasma membrane cell surface positive regulation of neuron projection development positive regulation of neuron projection development membrane membrane cell migration protein kinase binding regulation of cell-cell adhesion positive regulation of cell-cell adhesion carbohydrate binding apoptotic nuclear changes protein tyrosine kinase activator activity Hsp70 protein binding negative regulation of B cell proliferation neuron projection development neuron projection development anchored component of membrane T cell costimulation anchored component of external side of plasma membrane anchored component of external side of plasma membrane anchored component of external side of plasma membrane microvillus membrane chemokine receptor transport out of membrane raft negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production negative regulation of transforming growth factor beta3 production positive regulation of integrin activation positive regulation of integrin activation positive regulation of cell adhesion mediated by integrin positive regulation of cell adhesion mediated by integrin regulation of cell-cell adhesion mediated by integrin positive regulation of cell-cell adhesion mediated by integrin negative regulation of erythrocyte clearance homotypic cell-cell adhesion negative regulation of erythrocyte aggregation positive regulation of T cell homeostatic proliferation positive regulation of activated T cell proliferation regulation of phosphorylation cholesterol homeostasis positive regulation of MAP kinase activity regulation of MAPK cascade response to estrogen innate immune response membrane raft membrane raft regulation of B cell differentiation negative regulation of neuron differentiation respiratory burst negative regulation of T cell homeostatic proliferation positive regulation of alpha-beta T cell proliferation positive regulation of alpha-beta T cell proliferation synaptic vesicle endocytosis positive regulation of peptidyl-tyrosine phosphorylation negative regulation of neurogenesis positive regulation of calcium-mediated signaling Hsp90 protein binding ciliary membrane negative regulation of monocyte chemotactic protein-1 production apoptotic signaling pathway negative regulation of inflammatory response to wounding positive regulation of inflammatory response to wounding |
04640 |
| TC1100000995.mm.2 |
Mybbp1a |
MYB binding protein (P160) 1a |
11 |
72441326 |
NM_016776, BC048858, BC052889 NM_016776, BC048858, BC052889 NM_016776, BC048858, BC052889 |
18432 |
63 |
DNA binding transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleolus nucleolus nucleolus cytoplasm regulation of transcription, DNA-templated transcription factor binding zinc ion binding respiratory electron transport chain circadian regulation of gene expression cellular response to glucose starvation ribosome biogenesis NLS-dependent protein nuclear import complex intracellular membrane-bounded organelle sequence-specific DNA binding sequence-specific DNA binding negative regulation of transcription, DNA-templated rhythmic process E-box binding positive regulation of cell cycle arrest intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of anoikis |
|
| TC1900000205.mm.2 |
Ddb1 |
damage specific DNA binding protein 1 |
19 |
10605596 |
NM_015735, BC009661 NM_015735, BC009661 |
13194 |
77 |
nucleic acid binding DNA binding damaged DNA binding protein binding nucleus nucleus nucleoplasm cytoplasm DNA repair DNA repair ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process cellular response to DNA damage stimulus proteasomal protein catabolic process Wnt signaling pathway protein ubiquitination protein ubiquitination protein-macromolecule adaptor activity Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex protein-containing complex histone H2A monoubiquitination site of double-strand break regulation of circadian rhythm negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process protein-containing complex binding positive regulation of viral genome replication positive regulation of gluconeogenesis positive regulation of protein catabolic process positive regulation by virus of viral protein levels in host cell rhythmic process biological process involved in interaction with symbiont UV-damage excision repair WD40-repeat domain binding Cul4-RING E3 ubiquitin ligase complex cullin family protein binding regulation of mitotic cell cycle phase transition positive regulation of viral release from host cell |
03420 04120 |
| TC0700004451.mm.2 |
Mki67 |
antigen identified by monoclonal antibody Ki 67 |
7 |
-135689787 |
NM_001081117 |
17345 |
1917 |
nucleotide binding chromosome, centromeric region condensed chromosome condensed chromosome DNA binding ATP binding nucleus nucleus nucleoplasm chromosome nucleolus nucleolus cytoplasm cell cycle regulation of mitotic nuclear division protein C-terminus binding cell population proliferation nuclear body meiotic cell cycle regulation of chromosome segregation hepatocyte proliferation regulation of chromatin organization cholangiocyte proliferation |
|
| TC1300000572.mm.2 |
Iars |
isoleucine-tRNA synthetase |
13 |
49682129 |
NM_172015, BC067029 NM_172015, BC067029 |
105148 |
26 |
tRNA binding nucleotide binding aminoacyl-tRNA editing activity aminoacyl-tRNA ligase activity isoleucine-tRNA ligase activity isoleucine-tRNA ligase activity isoleucine-tRNA ligase activity ATP binding nucleoplasm cytoplasm cytosol translation tRNA aminoacylation for protein translation isoleucyl-tRNA aminoacylation isoleucyl-tRNA aminoacylation isoleucyl-tRNA aminoacylation ligase activity aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex GTPase binding |
00290 00970 |
| TC1400001676.mm.2 |
Sh3bp5 |
SH3-domain binding protein 5 (BTK-associated) |
14 |
-31372613, -31372613 |
NM_011894, BC018237, BC053741 NM_011894, BC018237, BC053741 NM_011894, BC018237, BC053741 |
24056 |
27 |
protein kinase inhibitor activity protein kinase inhibitor activity guanyl-nucleotide exchange factor activity nucleoplasm cytoplasm cytoplasm mitochondrion negative regulation of protein kinase activity membrane nuclear body SH3 domain binding cytoplasmic vesicle membrane cytoplasmic vesicle intracellular signal transduction intracellular signal transduction negative regulation of protein tyrosine kinase activity |
|
| TC0800003233.mm.2 |
Trmt1 |
tRNA methyltransferase 1 |
8 |
84689283, 84689246, 84686323 |
NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404 NM_001164559, NM_001164560, NM_198020, BC027404 |
212528 |
21 |
tRNA binding tRNA N2-guanine methylation RNA binding tRNA (guanine-N2-)-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity nucleus tRNA processing methyltransferase activity transferase activity methylation metal ion binding |
|
| TC0700002617.mm.2 |
Atp1a3 |
ATPase, Na+/K+ transporting, alpha 3 polypeptide |
7 |
-24978168, -24978168 |
BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 BC020177, BC034645, BC037206, BC042894, NM_144921 |
232975 |
83 |
nucleotide binding amyloid-beta binding photoreceptor inner segment P-type sodium:potassium-exchanging ATPase activity P-type sodium:potassium-exchanging ATPase activity ATP binding nucleus cytoplasm endoplasmic reticulum Golgi apparatus sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex ion transport potassium ion transport sodium ion transport cellular sodium ion homeostasis cellular sodium ion homeostasis cellular sodium ion homeostasis memory adult locomotory behavior visual learning potassium transmembrane transporter activity, phosphorylative mechanism membrane integral component of membrane cellular potassium ion homeostasis cellular potassium ion homeostasis axon organelle membrane D1 dopamine receptor binding ionotropic glutamate receptor signaling pathway sodium ion export across plasma membrane sodium ion export across plasma membrane sodium ion export across plasma membrane sarcolemma response to drug neuronal cell body myelin sheath myelin sheath heparan sulfate proteoglycan binding calyx of Held dendritic spine neck dendritic spine head synapse metal ion binding chaperone binding cardiac muscle contraction regulation of cardiac muscle cell membrane potential sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential postsynapse neuron to neuron synapse integral component of presynaptic membrane ion antiporter activity involved in regulation of presynaptic membrane potential proton transmembrane transport cellular response to amyloid-beta neuron projection maintenance potassium ion import across plasma membrane potassium ion import across plasma membrane |
04260 04960 04964 04970 04971 04972 04973 04974 04976 |
| TC0700002498.mm.2 |
Tomm40 |
translocase of outer mitochondrial membrane 40 |
7 |
-19701312 |
NM_001109748, NM_016871, BC100452 NM_001109748, NM_016871, BC100452 NM_001109748, NM_016871, BC100452 |
53333 |
30 |
cation channel activity mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial outer membrane translocase complex mitochondrial outer membrane translocase complex mitochondrial inner membrane cytosol protein targeting to mitochondrion ion transport protein transmembrane transporter activity protein transmembrane transporter activity protein transport porin activity membrane integral component of membrane protein import into mitochondrial matrix integral component of mitochondrial outer membrane integral component of mitochondrial membrane positive regulation of apoptotic process mitochondria-associated endoplasmic reticulum membrane pore complex protein insertion into mitochondrial membrane transmembrane transport preprotein binding |
05014 |
| TC0100000222.mm.2 |
Imp4 |
IMP4, U3 small nucleolar ribonucleoprotein |
1 |
34439828 |
NM_178601, BC069930 NM_178601, BC069930 |
27993 |
20 |
fibrillar center nucleus nucleolus nucleolus rRNA processing snoRNA binding preribosome small-subunit processome Mpp10 complex Mpp10 complex ribosome biogenesis |
03008 |
| TC1200001324.mm.2 |
Cdca7l |
cell division cycle associated 7 like |
12 |
117843860 |
NM_146040, BC006933 NM_146040, BC006933 |
217946 |
19 |
fibrillar center nucleus nucleus nucleoplasm nucleolus cytoplasm cytosol regulation of transcription, DNA-templated positive regulation of cell population proliferation |
|
| TC0400002457.mm.2 |
Nol6 |
nucleolar protein family 6 (RNA-associated) |
4 |
-41114426 |
NM_139236, BC059820 NM_139236, BC059820 |
230082 |
24 |
condensed nuclear chromosome RNA binding nucleus nucleoplasm chromosome nucleolus nucleolus mitochondrion rRNA processing tRNA export from nucleus small-subunit processome CURI complex UTP-C complex |
03008 |
| TC1200001051.mm.2 |
Glrx5 |
glutaredoxin 5 |
12 |
105032617 |
NM_028419, BC058371 NM_028419, BC058371 |
73046 |
22 |
nucleus mitochondrion mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix electron transfer activity protein disulfide oxidoreductase activity dendrite neuronal cell body [2Fe-2S] cluster assembly cell redox homeostasis metal ion binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding protein maturation by [2Fe-2S] cluster transfer protein maturation by [4Fe-4S] cluster transfer |
|
| TC0100000469.mm.2 |
Cyp20a1 |
cytochrome P450, family 20, subfamily a, polypeptide 1 |
1 |
60343299 |
NM_030013, BC049147 NM_030013, BC049147 |
77951 |
17 |
monooxygenase activity iron ion binding membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen heme binding metal ion binding |
|
| TC0800001594.mm.2 |
|
|
|
|
NM_008737, NR_035436, BC060129 NM_008737, NR_035436, BC060129 NM_008737, NR_035436, BC060129 |
|
|
angiogenesis angiogenesis angiogenesis branching involved in blood vessel morphogenesis neuron migration sprouting angiogenesis cell migration involved in sprouting angiogenesis cell migration involved in sprouting angiogenesis outflow tract septum morphogenesis vascular endothelial growth factor-activated receptor activity GTPase activator activity protein binding cytoplasm mitochondrion early endosome cytosol neurofilament plasma membrane plasma membrane plasma membrane focal adhesion focal adhesion substrate-dependent cell migration, cell extension integrin-mediated signaling pathway integrin-mediated signaling pathway multicellular organism development nervous system development axon guidance axon guidance axonal fasciculation heart development motor neuron axon guidance heparin binding animal organ morphogenesis cell surface positive regulation of endothelial cell migration positive regulation of endothelial cell migration membrane integral component of membrane dendrite development cell migration semaphorin receptor activity semaphorin receptor activity semaphorin receptor activity semaphorin receptor activity growth factor binding growth factor binding protein kinase binding facial nerve structural organization trigeminal nerve morphogenesis trigeminal nerve structural organization vestibulocochlear nerve structural organization nerve development branchiomotor neuron axon guidance gonadotrophin-releasing hormone neuronal migration to the hypothalamus cell differentiation axon axon growth cone negative regulation of axon extension retinal ganglion cell axon guidance actin cytoskeleton reorganization regulation of Cdc42 protein signal transduction regulation of Cdc42 protein signal transduction substrate adhesion-dependent cell spreading cellular response to hepatocyte growth factor stimulus endothelial cell chemotaxis cellular response to vascular endothelial growth factor stimulus ventral trunk neural crest cell migration vascular endothelial growth factor signaling pathway vascular endothelial growth factor binding vascular endothelial growth factor binding neuropilin signaling pathway neuropilin signaling pathway VEGF-activated neuropilin signaling pathway VEGF-activated neuropilin signaling pathway positive regulation of phosphorylation positive regulation of phosphorylation neuron projection neuronal cell body negative regulation of neuron apoptotic process endothelial cell migration endothelial cell migration positive regulation of angiogenesis viral entry into host cell metal ion binding platelet-derived growth factor receptor signaling pathway vascular endothelial growth factor receptor signaling pathway vascular endothelial growth factor receptor signaling pathway hepatocyte growth factor receptor signaling pathway sympathetic nervous system development neuron development regulation of axon extension involved in axon guidance positive regulation of axon extension involved in axon guidance negative regulation of axon extension involved in axon guidance negative regulation of axon extension involved in axon guidance artery morphogenesis axon extension involved in axon guidance positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive chemotaxis positive regulation of filopodium assembly positive regulation of filopodium assembly positive regulation of stress fiber assembly positive regulation of focal adhesion assembly axonogenesis involved in innervation dichotomous subdivision of terminal units involved in salivary gland branching dichotomous subdivision of terminal units involved in salivary gland branching angiogenesis involved in coronary vascular morphogenesis cell migration involved in coronary vasculogenesis coronary artery morphogenesis retina vasculature morphogenesis in camera-type eye renal artery morphogenesis sympathetic ganglion development trigeminal ganglion development positive regulation of ERK1 and ERK2 cascade semaphorin-plexin signaling pathway semaphorin-plexin signaling pathway semaphorin-plexin signaling pathway commissural neuron axon guidance positive regulation of cell migration involved in sprouting angiogenesis regulation of retinal ganglion cell axon guidance sensory neuron axon guidance sorting endosome motor neuron migration sympathetic neuron projection extension sympathetic neuron projection guidance glutamatergic synapse glutamatergic synapse integral component of postsynaptic membrane postsynapse organization postsynapse organization basal dendrite development basal dendrite arborization positive regulation of substrate adhesion-dependent cell spreading neural crest cell migration involved in autonomic nervous system development toxin transport semaphorin-plexin signaling pathway involved in neuron projection guidance semaphorin-plexin signaling pathway involved in axon guidance positive regulation of retinal ganglion cell axon guidance VEGF-activated neuropilin signaling pathway involved in axon guidance protein localization to early endosome facioacoustic ganglion development dorsal root ganglion morphogenesis otic placode development positive regulation of actin cytoskeleton reorganization negative regulation of extrinsic apoptotic signaling pathway |
|
| TC0800003236.mm.2 |
Usp10 |
ubiquitin specific peptidase 10 |
8 |
119910359 |
NM_009462, BC007134 NM_009462, BC007134 |
22224 |
38 |
p53 binding cysteine-type endopeptidase activity cysteine-type endopeptidase activity thiol-dependent ubiquitin-specific protease activity thiol-dependent ubiquitin-specific protease activity nucleus nucleus nucleoplasm cytoplasm endosome early endosome early endosome cytosol cytosol DNA repair ubiquitin-dependent protein catabolic process autophagy cellular response to DNA damage stimulus peptidase activity cysteine-type peptidase activity regulation of autophagy regulation of autophagy protein deubiquitination protein deubiquitination hydrolase activity DNA damage response, signal transduction by p53 class mediator DNA damage response, signal transduction by p53 class mediator protein-containing complex negative regulation of I-kappaB kinase/NF-kappaB signaling ion channel binding intermediate filament cytoskeleton cellular response to interleukin-1 |
|
| TC1000001298.mm.2 |
Nap1l1 |
nucleosome assembly protein 1-like 1 |
10 |
111473226 |
NM_001146707, NM_015781, BC076591 NM_001146707, NM_015781, BC076591 NM_001146707, NM_015781, BC076591 |
53605 |
44 |
chromatin chromatin binding protein binding nucleus nucleus cytoplasm cytoplasm nucleosome assembly nervous system development kinase binding histone binding neuron projection positive regulation of neurogenesis positive regulation of neural precursor cell proliferation |
|
| TC1900000718.mm.2 |
Pdcd11 |
programmed cell death 11 |
19 |
47090765 |
NM_011053, BC070468 NM_011053, BC070468 |
18572 |
30 |
nucleic acid binding RNA binding nucleus nucleolus cytosol rRNA processing RNA processing mRNA processing transcription factor binding small-subunit processome |
|
| TC1400001031.mm.2 |
Rcbtb2 |
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
14 |
73142509, 73142784 |
NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224 NM_001170694, NM_134083, NR_033185, BC003224 |
105670 |
17 |
acrosomal vesicle molecular_function biological_process cytoplasmic vesicle |
|
| TC0600001279.mm.2 |
Pparg |
peroxisome proliferator activated receptor gamma |
6 |
115422065, 115360950, 115362348, 115361143 |
NM_001127330, NM_011146, BC021798 NM_001127330, NM_011146, BC021798 NM_001127330, NM_011146, BC021798 |
19016 |
1453 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific negative regulation of cytokine production placenta development response to dietary excess diet induced thermogenesis negative regulation of acute inflammatory response DNA binding DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity steroid hormone receptor activity nuclear receptor activity nuclear receptor activity nuclear receptor activity nuclear receptor activity protein binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II fatty acid metabolic process activation of cysteine-type endopeptidase activity involved in apoptotic process inflammatory response signal transduction protein C-terminus binding transcription factor binding regulation of blood pressure zinc ion binding negative regulation of cell population proliferation negative regulation of cell population proliferation response to light stimulus hormone-mediated signaling pathway regulation of gene expression macrophage derived foam cell differentiation negative regulation of macrophage derived foam cell differentiation negative regulation of cholesterol storage negative regulation of cholesterol storage negative regulation of sequestering of triglyceride long-chain fatty acid transport negative regulation of angiogenesis regulation of lipid metabolic process regulation of lipid metabolic process fatty acid oxidation enzyme binding protein phosphatase binding cell differentiation monocyte differentiation negative regulation of cell growth estrogen receptor binding nuclear receptor coactivator activity negative regulation of BMP signaling pathway epithelial cell differentiation response to food cellular response to insulin stimulus cellular response to insulin stimulus negative regulation of collagen biosynthetic process activating transcription factor binding response to lipid response to lipid peroxisome proliferator activated receptor signaling pathway peroxisome proliferator activated receptor signaling pathway peptide binding glucose homeostasis regulation of circadian rhythm identical protein binding lipoprotein transport positive regulation of apoptotic process intracellular membrane-bounded organelle receptor complex positive regulation of DNA binding negative regulation of blood vessel endothelial cell migration sequence-specific DNA binding protein self-association cell fate commitment cell fate commitment fat cell differentiation fat cell differentiation fat cell differentiation fat cell differentiation regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation negative regulation of osteoblast differentiation negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of fatty acid metabolic process positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of fatty acid oxidation metal ion binding retinoid X receptor binding retinoic acid receptor signaling pathway retinoic acid receptor signaling pathway cell maturation perinuclear region of cytoplasm rhythmic process negative regulation of smooth muscle cell proliferation positive regulation of oligodendrocyte differentiation arachidonic acid binding DNA binding domain binding LBD domain binding WW domain binding negative regulation of inflammatory response white fat cell differentiation white fat cell differentiation brown fat cell differentiation positive regulation of DNA-binding transcription factor activity alpha-actinin binding negative regulation of telomerase activity positive regulation of phagocytosis, engulfment negative regulation of interferon-gamma-mediated signaling pathway negative regulation of gene silencing by miRNA E-box binding cellular response to lithium ion cellular response to low-density lipoprotein particle stimulus cellular response to organic cyclic compound negative regulation of peptide hormone secretion RNA polymerase II transcription regulator complex negative regulation of neuroinflammatory response negative regulation of cellular response to insulin stimulus positive regulation of pri-miRNA transcription by RNA polymerase II negative regulation of microglial cell activation negative regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell apoptotic process negative regulation of vascular endothelial cell proliferation positive regulation of low-density lipoprotein receptor activity promoter-specific chromatin binding negative regulation of pancreatic stellate cell proliferation negative regulation of signaling receptor activity |
03320 04380 05016 05200 05216 |
| TC1900000124.mm.2 |
Trmt112 |
tRNA methyltransferase 11-2 |
19 |
6909697 |
NM_001166370, NM_026306, BC016191, BC019418, BC087959 NM_001166370, NM_026306, BC016191, BC019418, BC087959 NM_001166370, NM_026306, BC016191, BC019418, BC087959 NM_001166370, NM_026306, BC016191, BC019418, BC087959 NM_001166370, NM_026306, BC016191, BC019418, BC087959 |
67674 |
23 |
protein binding nucleus nucleoplasm cytoplasm protein methyltransferase activity rRNA (guanine) methyltransferase activity peptidyl-glutamine methylation peptidyl-glutamine methylation peptidyl-glutamine methylation tRNA methylation rRNA methylation protein-containing complex histone lysine methylation protein heterodimerization activity perinuclear region of cytoplasm rRNA (guanine-N7)-methylation rRNA (guanine-N7)-methylation positive regulation of rRNA processing |
|
| TC1000000548.mm.2 |
Vsir |
V-set immunoregulatory receptor |
10 |
60346850 |
NM_001159572, NM_028732, BC003967 NM_001159572, NM_028732, BC003967 NM_001159572, NM_028732, BC003967 |
74048 |
43 |
negative regulation of T cell cytokine production protein binding plasma membrane plasma membrane external side of plasma membrane positive regulation of gene expression positive regulation of endopeptidase activity membrane integral component of membrane enzyme binding positive regulation of cell migration BMP signaling pathway positive regulation of BMP signaling pathway positive regulation of BMP signaling pathway zymogen activation negative regulation of interferon-gamma production negative regulation of interleukin-10 production negative regulation of interleukin-17 production negative regulation of tumor necrosis factor production identical protein binding positive regulation of regulatory T cell differentiation stem cell differentiation endopeptidase activator activity positive regulation of collagen catabolic process negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD8-positive, alpha-beta T cell proliferation positive regulation of stem cell differentiation |
|
| TC1800000708.mm.2 |
Psmg2 |
proteasome (prosome, macropain) assembly chaperone 2 |
18 |
67641586 |
NM_134138, BC016606 NM_134138, BC016606 |
107047 |
21 |
nucleus nucleus cytosol mitotic spindle assembly checkpoint negative regulation of apoptotic process proteasome assembly chaperone-mediated protein complex assembly regulation of cell cycle molecular adaptor activity chaperone complex |
|
| TC0400001158.mm.2 |
Kti12 |
KTI12 homolog, chromatin associated |
4 |
108847856 |
NM_029571, BC021493 NM_029571, BC021493 |
100087 |
12 |
nucleotide binding tRNA wobble uridine modification molecular_function ATP binding regulation of transcription by RNA polymerase II elongator holoenzyme complex |
|
| TC1100000407.mm.2 |
Nudcd2 |
NudC domain containing 2 |
11 |
40733660 |
NM_026023, BC005646 NM_026023, BC005646 |
52653 |
19 |
chromosome, centromeric region kinetochore chromosome cytoplasm cytosol cytoskeleton protein folding microtubule cytoskeleton intercellular bridge unfolded protein binding mitotic spindle |
|
| TC1500002221.mm.2 |
Cers5 |
ceramide synthase 5 |
15 |
-99735591 |
NM_028015, BC043059, BC046797 NM_028015, BC043059, BC046797 NM_028015, BC043059, BC046797 |
71949 |
46 |
DNA binding endoplasmic reticulum endoplasmic reticulum lipid metabolic process sphingolipid metabolic process membrane integral component of membrane N-acyltransferase activity transferase activity sphingolipid biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity |
|
| TC1900000572.mm.2 |
Entpd1 |
ectonucleoside triphosphate diphosphohydrolase 1 |
19 |
40659769, 40612365 |
NM_009848, BC011278 NM_009848, BC011278 |
12495 |
128 |
nucleotide binding guanosine-diphosphatase activity ATP binding basement membrane extracellular space plasma membrane G protein-coupled receptor signaling pathway synaptic vesicle nucleoside diphosphate catabolic process purine ribonucleoside diphosphate catabolic process external side of plasma membrane cell surface postsynaptic density membrane integral component of membrane basolateral plasma membrane hydrolase activity ATPase activity nucleoside-diphosphatase activity nucleoside-diphosphatase activity nucleoside-triphosphatase activity platelet activation negative regulation of dopamine secretion identical protein binding neuron projection neuronal cell body adenosine-diphosphatase activity adenosine-diphosphatase activity uridine-diphosphatase activity ADP catabolic process synaptic membrane 8-oxo-dGTP phosphohydrolase activity negative regulation of ATP biosynthetic process |
00230 00240 |
| TC1000000830.mm.2 |
Wdr18 |
WD repeat domain 18 |
10 |
79960151 |
NM_175450, BC095984 NM_175450, BC095984 |
216156 |
29 |
molecular_function nucleus nucleoplasm nuclear pre-replicative complex cytoplasm rRNA processing multicellular organism development regulation of DNA-dependent DNA replication initiation Rix1 complex |
|
| TC1600001559.mm.2 |
Fam162a |
family with sequence similarity 162, member A |
16 |
-36043843 |
NM_027342, BC010826 NM_027342, BC010826 |
70186 |
23 |
molecular_function mitochondrion mitochondrion mitochondrion cytosol apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process membrane integral component of membrane positive regulation of apoptotic process positive regulation of apoptotic process neuron apoptotic process neuron apoptotic process cellular response to hypoxia cellular response to hypoxia cellular response to hypoxia positive regulation of release of cytochrome c from mitochondria positive regulation of release of cytochrome c from mitochondria positive regulation of release of cytochrome c from mitochondria |
|
| TC1100003128.mm.2 |
Nlrp1c-ps |
NLR family, pyrin domain containing 1C, pseudogene |
11 |
-71242429 |
NR_027858, BC141384 NR_027858, BC141384 |
627984 |
2 |
|
|
| TC0700001400.mm.2 |
Lipt2 |
lipoyl(octanoyl) transferase 2 (putative) |
7 |
100159276 |
NM_026010, BC115472, BC115473 NM_026010, BC115472, BC115473 NM_026010, BC115472, BC115473 |
67164 |
15 |
protein binding mitochondrion mitochondrion mitochondrion cellular protein modification process protein lipoylation protein lipoylation transferase activity transferase activity, transferring acyl groups ligase activity lipoyl(octanoyl) transferase activity positive regulation of oxygen metabolic process |
00785 01100 |
| TC0200001760.mm.2 |
Rad51 |
RAD51 recombinase |
2 |
119112813 |
NM_011234, BC027384 NM_011234, BC027384 |
19361 |
173 |
recombinase activity nucleotide binding nuclear chromosome telomere maintenance via recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination DNA recombinase assembly DNA recombinase assembly chromosome, telomeric region chromosome, telomeric region chromatin condensed chromosome condensed nuclear chromosome condensed nuclear chromosome synaptonemal complex lateral element lateral element regulation of protein phosphorylation DNA binding chromatin binding chromatin binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding single-stranded DNA binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome cytoplasm cytoplasm mitochondrion cytoskeleton DNA metabolic process DNA unwinding involved in DNA replication DNA repair DNA recombination mitotic recombination cellular response to DNA damage stimulus cellular response to DNA damage stimulus reciprocal meiotic recombination reciprocal meiotic recombination protein C-terminus binding DNA-dependent ATPase activity regulation of double-strand break repair via homologous recombination telomere maintenance via telomere lengthening PML body single-stranded DNA helicase activity enzyme binding replication fork processing replication fork processing telomere organization protein-containing complex site of double-strand break interstrand cross-link repair strand invasion identical protein binding perinuclear region of cytoplasm positive regulation of DNA ligation meiotic cell cycle DNA polymerase binding chromosome organization involved in meiotic cell cycle chromosome organization involved in meiotic cell cycle cellular response to alkaloid cellular response to ionizing radiation cellular response to hydroxyurea cellular response to camptothecin replication-born double-strand break repair via sister chromatid exchange mitotic recombination-dependent replication fork processing |
03440 05200 05212 |
| TC0600000788.mm.2 |
Serbp1 |
serpine1 mRNA binding protein 1 |
6 |
67266978 |
NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 NM_001113564, NM_001113565, NM_001113566, NM_025814, BC013665, BC030502 |
66870 |
38 |
RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleus nucleus cytoplasm cytoplasm cytosol PML body organization SUMO binding |
|
| TC1200000988.mm.2 |
Tdp1 |
tyrosyl-DNA phosphodiesterase 1 |
12 |
99884517, 99884517 |
NM_028354, BC019804, BC065162 NM_028354, BC019804, BC065162 NM_028354, BC019804, BC065162 |
104884 |
35 |
single strand break repair single strand break repair single strand break repair double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding nuclease activity exonuclease activity nucleus nucleus nucleoplasm plasma membrane DNA repair DNA repair double-strand break repair double-strand break repair cellular response to DNA damage stimulus phosphoric diester hydrolase activity hydrolase activity 3'-tyrosyl-DNA phosphodiesterase activity 3'-tyrosyl-DNA phosphodiesterase activity intracellular membrane-bounded organelle |
|
| TC0800000846.mm.2 |
Mcm5 |
minichromosome maintenance complex component 5 |
8 |
75109508 |
NM_008566, BC094416 NM_008566, BC094416 |
17218 |
41 |
nucleotide binding double-strand break repair via break-induced replication DNA binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleoplasm chromosome cytoplasm DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA replication initiation cell cycle hydrolase activity single-stranded DNA helicase activity MCM complex MCM complex 3'-5' DNA helicase activity |
03030 04110 |
| TC0100003449.mm.2 |
Mpzl1 |
myelin protein zero-like 1 |
1 |
-165592175, -165592180 |
NM_001001880, NM_001083897, BC072563 NM_001001880, NM_001083897, BC072563 NM_001001880, NM_001083897, BC072563 |
68481 |
23 |
protein binding integral component of plasma membrane signal transduction membrane integral component of membrane positive regulation of cell migration |
04514 |
| TC0100001985.mm.2 |
Eya1 |
EYA transcriptional coactivator and phosphatase 1 |
1 |
-14168957 |
NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860 NM_001252192, NM_010164, BC060260, BC066860 |
14048 |
151 |
establishment of mitotic spindle orientation establishment of mitotic spindle orientation metanephros development ureteric bud development branching involved in ureteric bud morphogenesis outflow tract morphogenesis RNA binding phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm DNA repair double-strand break repair chromatin organization protein dephosphorylation cellular response to DNA damage stimulus multicellular organism development pattern specification process pattern specification process mesodermal cell fate specification animal organ morphogenesis response to ionizing radiation striated muscle tissue development histone dephosphorylation histone dephosphorylation nuclear body hydrolase activity protein sumoylation cell differentiation protein-containing complex protein-DNA complex cellular protein localization establishment or maintenance of apical/basal cell polarity peptidyl-tyrosine dephosphorylation aorta morphogenesis ear morphogenesis inner ear morphogenesis inner ear morphogenesis outer ear morphogenesis middle ear morphogenesis cell fate commitment regulation of neuron differentiation regulation of neuron differentiation positive regulation of DNA repair positive regulation of DNA repair positive regulation of Notch signaling pathway positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding neuron fate specification embryonic skeletal system morphogenesis semicircular canal morphogenesis anatomical structure development anatomical structure development positive regulation of epithelial cell proliferation pharyngeal system development lung epithelial cell differentiation otic vesicle development otic vesicle morphogenesis positive regulation of secondary heart field cardioblast proliferation cochlea morphogenesis negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
|
| TC0100002772.mm.2 |
|
|
|
|
NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 NM_172505, NM_198652, NR_040291, BC057309, BC062125, BC131919, BC100379 |
|
|
chromosome, centromeric region chromosome, centromeric region condensed chromosome kinetochore DNA binding nucleus nucleoplasm chromosome nucleolus mitochondrion cell cycle chromosome segregation CENP-A containing nucleosome assembly histone binding identical protein binding regulation of protein-containing complex assembly regulation of DNA binding |
|
| TC1700002534.mm.2 |
Dpy30 |
dpy-30, histone methyltransferase complex regulatory subunit |
17 |
-74299473, -74299473, -74299473, -74299473 |
NM_001146222, NM_001146223, NM_001146224, NM_024428, BC002240 NM_001146222, NM_001146223, NM_001146224, NM_024428, BC002240 NM_001146222, NM_001146223, NM_001146224, NM_024428, BC002240 NM_001146222, NM_001146223, NM_001146224, NM_024428, BC002240 NM_001146222, NM_001146223, NM_001146224, NM_024428, BC002240 |
66310 |
39 |
nucleus nucleoplasm Golgi apparatus trans-Golgi network chromatin organization chromatin silencing at telomere endosomal transport histone methyltransferase complex identical protein binding protein homodimerization activity MLL3/4 complex Set1C/COMPASS complex Set1C/COMPASS complex histone H3-K4 methylation histone H3-K4 methylation |
|
| TC1000001894.mm.2 |
Enpp1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
10 |
-24637913 |
NM_008813, BC160371 NM_008813, BC160371 |
18605 |
131 |
nucleic acid binding catalytic activity exonuclease activity phosphodiesterase I activity phosphodiesterase I activity phosphodiesterase I activity nucleotide diphosphatase activity nucleotide diphosphatase activity nucleotide diphosphatase activity scavenger receptor activity insulin receptor binding calcium ion binding ATP binding extracellular region extracellular space extracellular space plasma membrane integral component of plasma membrane generation of precursor metabolites and energy phosphate-containing compound metabolic process immune response zinc ion binding nucleoside triphosphate catabolic process nucleoside triphosphate catabolic process cell surface cell surface cell surface membrane integral component of membrane hydrolase activity polysaccharide binding negative regulation of ossification negative regulation of cell growth melanocyte differentiation regulation of bone mineralization negative regulation of bone mineralization inorganic diphosphate transport inorganic diphosphate transport cellular phosphate ion homeostasis sequestering of triglyceride biomineral tissue development negative regulation of protein autophosphorylation cellular response to insulin stimulus NADH pyrophosphatase activity identical protein binding protein homodimerization activity cell projection neuron projection neuronal cell body cell body synapse negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of glycogen biosynthetic process ATP metabolic process ATP metabolic process negative regulation of glucose import negative regulation of insulin receptor signaling pathway bone remodeling metal ion binding nucleoside-triphosphate diphosphatase activity nucleoside-triphosphate diphosphatase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process nucleic acid phosphodiester bond hydrolysis apical dendrite basal dendrite cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity negative regulation of hh target transcription factor activity |
00230 00500 00740 00760 00770 01100 |
| TC1300001635.mm.2 |
H2bc7 |
H2B clustered histone 7 |
13 |
-23573759 |
NM_178195, BC160307 NM_178195, BC160307 |
319180 |
6 |
innate immune response in mucosa DNA binding extracellular space nucleoplasm cytosol nucleosome assembly antibacterial humoral response identical protein binding defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide |
05322 |
| TC1900000960.mm.2 |
Banf1 |
BAF nuclear assembly factor 1 |
19 |
-5364632, -5364632 |
NM_001038231, NM_001286608, NM_011793, NR_104482, BC003709 NM_001038231, NM_001286608, NM_011793, NR_104482, BC003709 NM_001038231, NM_001286608, NM_011793, NR_104482, BC003709 NM_001038231, NM_001286608, NM_011793, NR_104482, BC003709 NM_001038231, NM_001286608, NM_011793, NR_104482, BC003709 |
23825 |
37 |
condensed chromosome DNA binding DNA binding DNA binding nucleus nucleoplasm nucleoplasm chromosome cytoplasm cytosol chromosome segregation protein C-terminus binding DNA integration enzyme binding chromosome condensation identical protein binding protein homodimerization activity negative regulation of viral genome replication protein N-terminus binding establishment of integrated proviral latency LEM domain binding |
|
| TC1900000127.mm.2 |
Ppp1r14b |
protein phosphatase 1, regulatory inhibitor subunit 14B |
19 |
6975047 |
NM_008889, BC082545, BC125650, BC125654 NM_008889, BC082545, BC125650, BC125654 NM_008889, BC082545, BC125650, BC125654 NM_008889, BC082545, BC125650, BC125654 |
18938 |
23 |
protein phosphatase inhibitor activity protein serine/threonine phosphatase inhibitor activity cytoplasm phosphatase inhibitor activity protein phosphatase regulator activity regulation of phosphorylation innate immune response |
|
| TC0900001101.mm.2 |
Ttk |
Ttk protein kinase |
9 |
83834688, 83834688 |
NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851 NM_001110265, NM_001284272, NM_009445, BC058851 |
22137 |
34 |
nucleotide binding kinetochore kinetochore protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus cytoplasm spindle protein phosphorylation chromosome segregation mitotic cell cycle checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint membrane kinase activity phosphorylation female meiosis chromosome segregation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation meiotic spindle assembly checkpoint meiotic spindle assembly checkpoint protein localization to kinetochore protein localization to kinetochore protein localization to chromosome identical protein binding kinetochore binding protein autophosphorylation chromosome separation meiotic prometaphase I protein localization to meiotic spindle midzone |
04110 |
| TC0300001181.mm.2 |
Dph5 |
diphthamide biosynthesis 5 |
3 |
115888182 |
NM_027193, BC060372 NM_027193, BC060372 |
69740 |
16 |
diphthine synthase activity cellular_component methyltransferase activity transferase activity peptidyl-diphthamide biosynthetic process from peptidyl-histidine methylation |
|
| TC1400000975.mm.2 |
Entpd4 |
ectonucleoside triphosphate diphosphohydrolase 4 |
14 |
69337150, 69555400 |
BC043134, NM_026174 BC043134, NM_026174 |
67464 |
23 |
Golgi membrane autophagosome membrane guanosine-diphosphatase activity guanosine-diphosphatase activity Golgi apparatus UDP catabolic process nucleoside diphosphate catabolic process membrane nucleoside-diphosphatase activity nucleoside-diphosphatase activity nucleoside-triphosphatase activity integral component of Golgi membrane cytidine-diphosphatase activity CTPase activity uridine-diphosphatase activity uridine-diphosphatase activity integral component of autophagosome membrane |
00230 00240 04142 |
| TC1100000892.mm.2 |
Aurkb |
aurora kinase B |
11 |
69045636 |
NM_011496, BC003261 NM_011496, BC003261 |
20877 |
114 |
negative regulation of transcription by RNA polymerase II nucleotide binding chromosome, centromeric region kinetochore condensed chromosome, centromeric region condensed chromosome, centromeric region negative regulation of B cell apoptotic process protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm spindle cytoskeleton spindle microtubule protein phosphorylation cell cycle spindle organization mitotic spindle organization mitotic spindle assembly checkpoint chromocenter kinase activity phosphorylation transferase activity kinase binding midbody midbody spindle pole centrosome negative regulation of protein binding chromosome passenger complex chromosome passenger complex chromosome passenger complex positive regulation of telomere maintenance via telomerase regulation of cytokinesis positive regulation of cytokinesis protein localization to kinetochore cellular response to UV histone serine kinase activity histone serine kinase activity cleavage furrow formation histone H3-S28 phosphorylation metal ion binding spindle midzone mitotic spindle midzone assembly cell division positive regulation of telomerase activity mitotic spindle pole mitotic spindle pole positive regulation of telomere capping positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore mitotic spindle midzone |
|
| TC0100003786.mm.2 |
Smyd2 |
SET and MYND domain containing 2 |
1 |
-189880491 |
NM_026796, BC023119 NM_026796, BC023119 |
226830 |
30 |
negative regulation of transcription by RNA polymerase II RNA polymerase II complex binding p53 binding protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol chromatin organization methyltransferase activity negative regulation of cell population proliferation protein-lysine N-methyltransferase activity histone methylation transferase activity histone-lysine N-methyltransferase activity peptidyl-lysine monomethylation peptidyl-lysine dimethylation methylation histone lysine methylation regulation of DNA damage response, signal transduction by p53 class mediator metal ion binding histone methyltransferase activity (H3-K36 specific) |
|
| TC0600000648.mm.2 |
Chn2 |
chimerin 2 |
6 |
54039931, 54272821, 54269155, 54264857 |
NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060 NM_001163640, NM_023543, BC051139, BC141060 |
69993 |
32 |
GTPase activator activity GTPase activator activity signal transduction membrane intracellular signal transduction regulation of GTPase activity synapse metal ion binding |
|
| MG-1-pos-10342180_st |
|
|
|
|
|
|
|
|
|
| TC0100002033.mm.2 |
Mcm3 |
minichromosome maintenance complex component 3 |
1 |
-20802967 |
NM_008563, BC031700 NM_008563, BC031700 |
17215 |
65 |
nucleotide binding double-strand break repair via break-induced replication DNA binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleus nucleoplasm chromosome cytoplasm centrosome DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cell cycle hydrolase activity MCM complex MCM complex perinuclear region of cytoplasm mitotic DNA replication initiation |
03030 04110 |
| TC0400001465.mm.2 |
Clspn |
claspin |
4 |
126556979 |
NM_175554, BC050848 NM_175554, BC050848 |
269582 |
26 |
DNA replication checkpoint DNA damage checkpoint DNA secondary structure binding DNA binding nucleus nucleoplasm chromosome Golgi apparatus DNA repair cellular response to DNA damage stimulus cell cycle mitotic G2 DNA damage checkpoint mitotic G2 DNA damage checkpoint anaphase-promoting complex binding anaphase-promoting complex binding peptidyl-serine phosphorylation activation of protein kinase activity activation of protein kinase activity mitotic DNA replication checkpoint mitotic DNA replication checkpoint |
|
| TC0900002044.mm.2 |
Slc37a2 |
solute carrier family 37 (glycerol-3-phosphate transporter), member 2 |
9 |
-37229148 |
NM_001145960, NM_020258, BC063326 NM_001145960, NM_020258, BC063326 NM_001145960, NM_020258, BC063326 |
56857 |
18 |
endoplasmic reticulum glycerol-3-phosphate metabolic process glycerophosphate shuttle carbohydrate transport glycerol-3-phosphate transmembrane transporter activity antiporter activity glucose-6-phosphate transport glucose-6-phosphate transport glycerol-3-phosphate transmembrane transport membrane integral component of membrane transmembrane transporter activity integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane phosphate ion transmembrane transport phosphate ion transmembrane transport transmembrane transport glucose 6-phosphate:inorganic phosphate antiporter activity glucose 6-phosphate:inorganic phosphate antiporter activity |
|
| TC0100003697.mm.2 |
Lbr |
lamin B receptor |
1 |
-181815314 |
NM_133815, BC021516, BC042522 NM_133815, BC021516, BC042522 NM_133815, BC021516, BC042522 |
98386 |
67 |
DNA binding protein binding nucleus nuclear envelope nuclear envelope nuclear inner membrane nuclear inner membrane nuclear pore nuclear lamina cytoplasm endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process nuclear localization sequence binding steroid metabolic process cholesterol metabolic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor neutrophil differentiation nuclear membrane nuclear membrane delta14-sterol reductase activity delta14-sterol reductase activity chaperone binding chromo shadow domain binding NADPH binding |
|
| TC0600001033.mm.2 |
Ruvbl1 |
RuvB-like protein 1 |
6 |
88465408 |
NM_019685, BC004718 NM_019685, BC004718 |
56505 |
53 |
nucleotide binding box C/D snoRNP assembly Swr1 complex Swr1 complex TFIID-class transcription factor complex binding DNA helicase activity DNA helicase activity transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleoplasm cytosol DNA repair DNA recombination chromatin organization chromatin remodeling regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus cell cycle positive regulation of plasminogen activation nuclear matrix histone acetylation hydrolase activity ATPase activity TBP-class protein binding Ino80 complex Ino80 complex protein-containing complex NuA4 histone acetyltransferase complex NuA4 histone acetyltransferase complex regulation of growth 3'-5' DNA helicase activity 5'-3' DNA helicase activity ADP binding histone H4 acetylation histone H2A acetylation ATPase binding cell division MLL1 complex positive regulation of canonical Wnt signaling pathway R2TP complex R2TP complex ribonucleoprotein complex regulation of fibroblast apoptotic process |
04310 |
| TC0700001455.mm.2 |
Rrm1 |
ribonucleotide reductase M1 |
7 |
102441694 |
NM_009103, BC016450, BC066217 NM_009103, BC016450, BC066217 NM_009103, BC016450, BC066217 |
20133 |
53 |
nucleotide binding catalytic activity ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding ATP binding nuclear envelope cytoplasm cytosol ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex DNA replication metabolic process deoxyribonucleotide biosynthetic process deoxyribonucleotide biosynthetic process oxidoreductase activity purine nucleotide binding identical protein binding cell projection neuronal cell body protein heterotetramerization ribonucleoside-diphosphate reductase activity disordered domain specific binding |
00230 00240 00480 01100 |
| TC1700002414.mm.2 |
Rab31 |
RAB31, member RAS oncogene family |
17 |
-65651725 |
NM_133685, BC013063 NM_133685, BC013063 |
106572 |
25 |
nucleotide binding phagocytic cup GTPase activity protein binding GTP binding cytoplasm endosome early endosome late endosome Golgi apparatus trans-Golgi network intracellular protein transport endomembrane system membrane GDP binding cytoplasmic vesicle receptor internalization trans-Golgi network membrane trans-Golgi network membrane cellular response to insulin stimulus early phagosome membrane Golgi to plasma membrane protein transport Golgi to plasma membrane protein transport regulated exocytosis phagocytic vesicle Golgi vesicle transport positive regulation of phagocytosis, engulfment phagosome maturation |
04144 |
| MG-1-pos-10340444_st |
|
|
|
|
|
|
|
|
|
| TC0700003829.mm.2 |
P2ry6 |
pyrimidinergic receptor P2Y, G-protein coupled, 6 |
7 |
-100937633 |
NM_183168, BC027331, BC064095 NM_183168, BC027331, BC064095 NM_183168, BC027331, BC064095 |
233571 |
54 |
G protein-coupled ADP receptor activity G protein-coupled receptor activity plasma membrane phagocytosis signal transduction G protein-coupled receptor signaling pathway positive regulation of smooth muscle cell migration membrane integral component of membrane basolateral plasma membrane apical plasma membrane pyrimidine nucleotide binding transepithelial chloride transport positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor activity G protein-coupled UDP receptor activity G protein-coupled UDP receptor activity G protein-coupled UTP receptor activity positive regulation of ERK1 and ERK2 cascade cellular response to prostaglandin E stimulus cellular response to organic cyclic compound cellular response to purine-containing compound positive regulation of vascular associated smooth muscle cell proliferation cellular response to pyrimidine ribonucleotide |
04080 |
| TC1300001555.mm.2 |
H2bc13 |
H2B clustered histone 13 |
13 |
-21715710 |
NM_178199 |
319185 |
9 |
innate immune response in mucosa extracellular space nucleoplasm cytosol antibacterial humoral response identical protein binding defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide |
05322 |
| MG-1-pos-10341381_st |
|
|
|
|
|
|
|
|
|
| TC0200004598.mm.2 |
Ckap2l |
cytoskeleton associated protein 2-like |
2 |
-129268209 |
NM_181589, BC053443 NM_181589, BC053443 |
70466 |
18 |
molecular_function cytoplasm centrosome centrosome cytosol cytosol cytoskeleton biological_process mitotic spindle mitotic spindle |
|
| TC0300002797.mm.2 |
S1pr1 |
sphingosine-1-phosphate receptor 1 |
3 |
-115710432 |
NM_007901, BC049094, BC051023 NM_007901, BC049094, BC051023 NM_007901, BC049094, BC051023 |
13609 |
252 |
angiogenesis angiogenesis G protein-coupled receptor binding blood vessel maturation cardiac muscle tissue growth involved in heart morphogenesis sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway G protein-coupled receptor activity G protein-coupled receptor activity nucleoplasm cytoplasm endosome plasma membrane chemotaxis signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway brain development positive regulation of cell population proliferation external side of plasma membrane membrane integral component of membrane cell migration regulation of metabolic process lamellipodium assembly regulation of cell adhesion positive regulation of cell migration regulation of bone mineralization leukocyte chemotaxis intrinsic component of plasma membrane actin cytoskeleton reorganization sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity intracellular membrane-bounded organelle positive regulation of GTPase activity regulation of bone resorption positive regulation of transcription by RNA polymerase II sphingolipid binding positive regulation of smooth muscle cell proliferation positive regulation of positive chemotaxis positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway negative regulation of stress fiber assembly heart trabecula morphogenesis T cell migration |
04080 |
| TC0800001245.mm.2 |
Slc7a6 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 |
8 |
106168853, 106168920 |
NM_178798, BC038404 NM_178798, BC038404 |
330836 |
20 |
amino acid transmembrane transport plasma membrane amino acid transport basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity antiporter activity ornithine transport membrane integral component of membrane transmembrane transporter activity intracellular membrane-bounded organelle transmembrane transport basic amino acid transmembrane transport |
|
| TC1800000528.mm.2 |
Sncaip |
synuclein, alpha interacting protein (synphilin) |
18 |
52768092, 52767810, 52768143 |
NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 NM_001199151, NM_001199153, NM_001199154, NM_026408, BC098489 |
67847 |
40 |
nucleoplasm cytoplasm cell death ubiquitin protein ligase binding cytoplasmic ribonucleoprotein granule dopamine metabolic process identical protein binding regulation of neurotransmitter secretion regulation of inclusion body assembly |
05012 |
| TC0700001736.mm.2 |
Eef2k |
eukaryotic elongation factor-2 kinase |
7 |
120843599, 120851188, 120842830 |
NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 NM_001267710, NM_001267711, NM_007908, BC003433, BC055361, NM_001251826 |
13631 |
47 |
nucleotide binding protein serine/threonine kinase activity elongation factor-2 kinase activity elongation factor-2 kinase activity calcium ion binding calmodulin binding calmodulin binding ATP binding translational elongation protein phosphorylation translation factor activity, RNA binding postsynaptic density kinase activity phosphorylation transferase activity regulation of protein autophosphorylation negative regulation of apoptotic process dendritic spine positive regulation of endocytosis protein autophosphorylation positive regulation of synapse assembly positive regulation of dendritic spine morphogenesis |
|
| TC1100001095.mm.2 |
Tlcd3a |
TLC domain containing 3A |
11 |
76202091, 76179670, 76179670 |
NM_027773, BC115519, BC115520 NM_027773, BC115519, BC115520 NM_027773, BC115519, BC115520 |
116972 |
15 |
molecular_function endoplasmic reticulum plasma membrane membrane integral component of membrane lipid homeostasis |
|
| TC0600000772.mm.2 |
Mad2l1 |
MAD2 mitotic arrest deficient-like 1 |
6 |
66535220 |
NM_019499, BC089012 NM_019499, BC089012 |
56150 |
81 |
mitotic sister chromatid segregation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore kinetochore spindle pole protein binding nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm cytoplasm cytosol cytoskeleton cell cycle mitotic cell cycle checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint mitotic spindle assembly checkpoint protein C-terminus binding negative regulation of protein catabolic process identical protein binding protein homodimerization activity negative regulation of apoptotic process negative regulation of apoptotic process nuclear pore nuclear basket negative regulation of mitotic metaphase/anaphase transition negative regulation of mitotic cell cycle perinuclear region of cytoplasm cell division establishment of centrosome localization mitotic spindle positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of mitotic cell cycle spindle assembly checkpoint negative regulation of ubiquitin protein ligase activity |
04110 04114 04914 |
| TC1500002141.mm.2 |
Slc38a1 |
solute carrier family 38, member 1 |
15 |
-96571417, -96571417, -96571417 |
NM_001166456, NM_001166458, NM_134086, BC030378 NM_001166456, NM_001166458, NM_134086, BC030378 NM_001166456, NM_001166458, NM_134086, BC030378 NM_001166456, NM_001166458, NM_134086, BC030378 |
105727 |
45 |
amino acid transmembrane transport neutral amino acid:sodium symporter activity plasma membrane plasma membrane integral component of plasma membrane ion transport sodium ion transport amino acid transport glutamine transport glutamine transport amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-glutamine transmembrane transporter activity L-glutamine transmembrane transporter activity symporter activity neutral amino acid transport membrane integral component of membrane basolateral plasma membrane axon neuronal cell body external side of apical plasma membrane L-alpha-amino acid transmembrane transport |
|
| TC0500002152.mm.2 |
Tyms |
thymidylate synthase |
5 |
-30058199 |
NM_021288, NR_033402, BC020139 NM_021288, NR_033402, BC020139 NM_021288, NR_033402, BC020139 |
22171 |
38 |
translation repressor activity, mRNA regulatory element binding mRNA binding thymidylate synthase activity thymidylate synthase activity folic acid binding nucleus nucleolus cytoplasm mitochondrion mitochondrion mitochondrial inner membrane mitochondrial matrix cytosol dTMP biosynthetic process dTMP biosynthetic process regulation of translation methyltransferase activity nucleotide biosynthetic process membrane transferase activity negative regulation of translation methylation tetrahydrofolate interconversion protein homodimerization activity heterocyclic compound binding sequence-specific mRNA binding |
00240 00670 01100 |
| TC0800002153.mm.2 |
Ankrd37 |
ankyrin repeat domain 37 |
8 |
-45996907 |
NM_001039562, BC039642, BC092377 NM_001039562, BC039642, BC092377 NM_001039562, BC039642, BC092377 |
654824 |
14 |
protein binding nucleus nucleoplasm cytoplasm mitochondrion cytosol biological_process |
|
| TC1300001777.mm.2 |
Serpinb6a |
serine (or cysteine) peptidase inhibitor, clade B, member 6a |
13 |
-33917917, -33917917 |
NM_001164117, NM_001164118, NM_001243192, NM_009254, BC006766, BC057950 NM_001164117, NM_001164118, NM_001243192, NM_009254, BC006766, BC057950 NM_001164117, NM_001164118, NM_001243192, NM_009254, BC006766, BC057950 NM_001164117, NM_001164118, NM_001243192, NM_009254, BC006766, BC057950 NM_001164117, NM_001164118, NM_001243192, NM_009254, BC006766, BC057950 NM_001164117, NM_001164118, NM_001243192, NM_009254, BC006766, BC057950 |
20719 |
40 |
protease binding serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding extracellular space cytoplasm cytoplasm cytoplasm sensory perception of sound gonad development negative regulation of peptidase activity negative regulation of endopeptidase activity negative regulation of endopeptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity collagen-containing extracellular matrix cellular response to osmotic stress serine protease inhibitor complex |
05146 |
| TC1800000509.mm.2 |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
18 |
50128200 |
NM_008292, BC022175 NM_008292, BC022175 |
15488 |
55 |
very long-chain fatty acid metabolic process 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity enoyl-CoA hydratase activity enoyl-CoA hydratase activity estradiol 17-beta-dehydrogenase activity protein binding mitochondrion peroxisome peroxisome peroxisome peroxisomal matrix lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation fatty acid beta-oxidation fatty acid beta-oxidation androgen metabolic process estrogen metabolic process oxidoreductase activity long-chain-enoyl-CoA hydratase activity lyase activity isomerase activity 3-hydroxyacyl-CoA dehydratase activity 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity very long-chain fatty-acyl-CoA metabolic process medium-chain fatty-acyl-CoA metabolic process identical protein binding protein homodimerization activity 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 17-beta-hydroxysteroid dehydrogenase (NAD+) activity Sertoli cell development |
00120 01100 04146 |
| TC1300001353.mm.2 |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 |
13 |
119690350 |
NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 NM_145942, BC023851, BC029693, BC031363, BC034317 |
208715 |
44 |
catalytic activity hydroxymethylglutaryl-CoA synthase activity hydroxymethylglutaryl-CoA synthase activity cytoplasm cytosol cytosol acetyl-CoA metabolic process lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process farnesyl diphosphate biosynthetic process, mevalonate pathway response to purine-containing compound sterol biosynthetic process transferase activity isomerase activity small molecule binding protein homodimerization activity organic acid binding cellular response to low-density lipoprotein particle stimulus |
00072 00280 00650 00900 01100 |
| TC0700003581.mm.2 |
Idh2 |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
7 |
-80094846 |
NM_173011, BC060030 NM_173011, BC060030 |
269951 |
84 |
magnesium ion binding isocitrate dehydrogenase activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity mitochondrion mitochondrion mitochondrion mitochondrial inner membrane peroxisome cytosol glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process NADP metabolic process NADP biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor metal ion binding NAD binding negative regulation of glial cell proliferation negative regulation of glial cell migration negative regulation of matrix metallopeptidase secretion |
00020 00480 01100 04146 |
| TC0700000652.mm.2 |
Cebpa |
CCAAT/enhancer binding protein (C/EBP), alpha |
7 |
35119292, 35119292 |
NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 NM_001287514, NM_001287515, NM_001287521, NM_001287523, NM_007678, BC011118, BC028890, BC051102, BC058161 |
12606 |
476 |
urea cycle negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase I transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific liver development embryonic placenta development DNA binding DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex nucleolus regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase I mitochondrion organization Notch signaling pathway multicellular organism development transcription factor binding transcription factor binding cholesterol metabolic process negative regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation positive regulation of gene expression nuclear matrix cytokine-mediated signaling pathway kinase binding kinase binding protein domain specific binding myeloid cell differentiation myeloid cell differentiation macrophage differentiation lung development granulocyte differentiation granulocyte differentiation protein-containing complex Rb-E2F complex CHOP-C/EBP complex regulation of cell population proliferation glucose homeostasis identical protein binding protein homodimerization activity histone deacetylase binding positive regulation of macrophage activation intracellular membrane-bounded organelle sequence-specific DNA binding sequence-specific DNA binding protein-containing complex binding fat cell differentiation fat cell differentiation fat cell differentiation positive regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of osteoblast differentiation negative regulation of cell cycle negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III protein heterodimerization activity cell maturation inner ear development positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation lipid homeostasis interleukin-6-mediated signaling pathway cellular response to lithium ion cellular response to tumor necrosis factor cellular response to organic cyclic compound HMG box domain binding RNA polymerase II transcription regulator complex positive regulation of DNA-templated transcription, initiation |
05200 05221 |
| TC1200001834.mm.2 |
Mis18bp1 |
MIS18 binding protein 1 |
12 |
-65132734 |
NM_172578, BC052175 NM_172578, BC052175 |
217653 |
24 |
chromosome, centromeric region condensed nuclear chromosome kinetochore DNA binding protein binding nucleus chromosome cell cycle cell division |
|
| TC0400002271.mm.2 |
Wwp1 |
WW domain containing E3 ubiquitin protein ligase 1 |
4 |
-19608299 |
NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 NM_001276292, NM_177327, NR_074089, NR_074090, BC026829, BC150812 |
107568 |
40 |
protein polyubiquitination ubiquitin-protein transferase activity ubiquitin-protein transferase activity protein binding nucleus cytoplasm cytosol plasma membrane ubiquitin-dependent protein catabolic process membrane protein ubiquitination protein ubiquitination protein ubiquitination transferase activity T cell differentiation lung development proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of protein catabolic process negative regulation of transcription, DNA-templated ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity |
04120 04144 |
| TC0800002399.mm.2 |
Gdf15 |
growth differentiation factor 15 |
8 |
-70629392, -70629392 |
NM_011819, BC067248 NM_011819, BC067248 |
23886 |
112 |
activation of MAPK activity activation of MAPK activity reduction of food intake in response to dietary excess reduction of food intake in response to dietary excess reduction of food intake in response to dietary excess cytokine activity extracellular region extracellular region extracellular space extracellular space nucleus cytoplasm Golgi apparatus growth factor activity positive regulation of pathway-restricted SMAD protein phosphorylation BMP signaling pathway glial cell-derived neurotrophic factor receptor signaling pathway negative regulation of multicellular organism growth protein homodimerization activity protein homodimerization activity positive regulation of MAPK cascade positive regulation of protein kinase B signaling SMAD protein signal transduction SMAD protein signal transduction negative regulation of growth hormone receptor signaling pathway BMP receptor binding positive regulation of myoblast fusion |
|
| TC0500002240.mm.2 |
Nop14 |
NOP14 nucleolar protein |
5 |
-34638535 |
NM_029278, BC024998, BC043043 NM_029278, BC024998, BC043043 NM_029278, BC024998, BC043043 |
75416 |
21 |
nucleus nucleoplasm nucleolus nucleolus rRNA processing enzyme binding maturation of SSU-rRNA Noc4p-Nop14p complex small-subunit processome ribosome biogenesis |
|
| TC0100002354.mm.2 |
Hspd1 |
heat shock protein 1 (chaperonin) |
1 |
-55077833, -55077832 |
NM_010477, BC016400 NM_010477, BC016400 |
15510 |
137 |
nucleotide binding lipopolysaccharide binding lipopolysaccharide binding p53 binding MyD88-dependent toll-like receptor signaling pathway positive regulation of T cell mediated immune response to tumor cell double-stranded RNA binding ATP binding extracellular space cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane mitochondrial matrix mitochondrial matrix early endosome peroxisomal matrix rough endoplasmic reticulum Golgi apparatus cytosol plasma membrane plasma membrane clathrin-coated pit protein folding activation of cysteine-type endopeptidase activity involved in apoptotic process response to unfolded protein high-density lipoprotein particle binding apoptotic mitochondrial changes apoptotic mitochondrial changes cell surface membrane isomerase activity enzyme binding mitochondrial crista coated vesicle secretory granule secretory granule ubiquitin protein ligase binding Golgi cisterna positive regulation of interferon-alpha production positive regulation of interferon-alpha production positive regulation of interferon-alpha production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interferon-gamma production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production protein-containing complex apolipoprotein binding apolipoprotein A-I binding mitochondrial unfolded protein response protein refolding B cell proliferation T cell activation T cell activation T cell activation T cell activation B cell activation zymogen granule positive regulation of macrophage activation positive regulation of apoptotic process negative regulation of apoptotic process myelin sheath intracellular membrane-bounded organelle negative regulation of neuron apoptotic process protein-containing complex binding protein import into mitochondrial intermembrane space membrane raft lipopolysaccharide receptor complex isotype switching to IgG isotypes positive regulation of inflammatory response protein stabilization positive regulation of T cell activation positive regulation of T cell activation positive regulation of T cell activation chaperone binding chaperone binding biological process involved in interaction with symbiont extracellular exosome negative regulation of apoptotic process in bone marrow cell cellular response to interleukin-7 modification-dependent protein binding negative regulation of reactive oxygen species biosynthetic process |
03018 04940 |
| TC1900001095.mm.2 |
Fads2 |
fatty acid desaturase 2 |
19 |
-10062764 |
NM_019699, BC057189 NM_019699, BC057189 |
56473 |
39 |
stearoyl-CoA 9-desaturase activity endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process membrane integral component of membrane linoleoyl-CoA desaturase activity oxidoreductase activity |
00592 01040 03320 |
| TC0500003369.mm.2 |
Gtf2i |
general transcription factor II I |
5 |
-134237831, -134237831 |
NM_001080746, NM_001080747, NM_001080748, NM_001080749, NM_010365, BC053044 NM_001080746, NM_001080747, NM_001080748, NM_001080749, NM_010365, BC053044 NM_001080746, NM_001080747, NM_001080748, NM_001080749, NM_010365, BC053044 NM_001080746, NM_001080747, NM_001080748, NM_001080749, NM_010365, BC053044 NM_001080746, NM_001080747, NM_001080748, NM_001080749, NM_010365, BC053044 NM_001080746, NM_001080747, NM_001080748, NM_001080749, NM_010365, BC053044 |
14886 |
81 |
RNA polymerase II activating transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm transcription by RNA polymerase II embryo development transition between slow and fast fiber negative regulation of angiogenesis cell projection neuronal cell body mitogen-activated protein kinase binding negative regulation of cytosolic calcium ion concentration positive regulation of DNA repair by transcription from RNA polymerase II promoter |
03022 |
| TC0200005334.mm.2 |
|
|
|
|
NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 |
|
|
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific cellular_component regulation of transcription by RNA polymerase II |
|
| TC0400001274.mm.2 |
Eif2b3 |
eukaryotic translation initiation factor 2B, subunit 3 |
4 |
117019401, 117019401 |
NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658 NM_001111277, NM_175135, BC115657, BC115658 |
108067 |
22 |
cytoplasmic translational initiation translation initiation factor activity translation initiation factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity cytoplasm eukaryotic translation initiation factor 2B complex eukaryotic translation initiation factor 2B complex translational initiation translation factor activity, RNA binding response to heat response to glucose oligodendrocyte development guanyl-nucleotide exchange factor complex response to peptide hormone T cell receptor signaling pathway |
03013 |
| TC0100002583.mm.2 |
Tmbim1 |
transmembrane BAX inhibitor motif containing 1 |
1 |
-74288246 |
NM_027154, BC004752 NM_027154, BC004752 |
69660 |
23 |
death receptor binding lysosome lysosomal membrane endosome Golgi apparatus endosome membrane membrane integral component of membrane negative regulation of catalytic activity intracellular membrane-bounded organelle negative regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of Fas signaling pathway negative regulation of protein localization to plasma membrane positive regulation of blood vessel remodeling |
|
| TC1300000240.mm.2 |
|
|
|
|
NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 NM_178188, NM_178203, NM_178204, BC119295, BC119297, BC127164, BC160302, BC160303 |
|
|
nuclear chromosome nucleosome DNA binding nucleus nucleus nucleosome assembly DNA replication-dependent nucleosome assembly chromatin silencing negative regulation of cell population proliferation enzyme binding protein-containing complex regulation of gene silencing |
|
| TC0200002876.mm.2 |
Camk1d |
calcium/calmodulin-dependent protein kinase ID |
2 |
-5293456, -5293456 |
NM_177343, BC141413, BC141414 NM_177343, BC141413, BC141414 NM_177343, BC141413, BC141414 |
227541 |
27 |
nucleotide binding catalytic activity protein kinase activity protein serine/threonine kinase activity calmodulin-dependent protein kinase activity calmodulin-dependent protein kinase activity calmodulin binding ATP binding intracellular anatomical structure nucleus cytoplasm cytoplasm protein phosphorylation inflammatory response nervous system development metabolic process positive regulation of neuron projection development kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation positive regulation of CREB transcription factor activity positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of phagocytosis regulation of dendrite development positive regulation of respiratory burst regulation of granulocyte chemotaxis positive regulation of neutrophil chemotaxis |
|
| MG-1-pos-10339928_st |
|
|
|
|
|
|
|
|
|
| TC0800001231.mm.2 |
|
|
|
|
NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 NM_026532, NR_033574, BC003955, BC083165, BC086773 |
|
|
nuclear outer membrane nucleoplasm cytosol protein import into nucleus protein import into nucleus protein import into nucleus protein export from nucleus nucleocytoplasmic transport structural constituent of nuclear pore small GTPase binding nuclear membrane positive regulation of protein import into nucleus identical protein binding nuclear pore central transport channel nuclear pore central transport channel nuclear import signal receptor activity protein localization to nuclear pore nucleocytoplasmic carrier activity negative regulation of vascular endothelial growth factor production |
|
| TC0900002451.mm.2 |
Kif23 |
kinesin family member 23 |
9 |
-61917277 |
NM_024245, BC047273 NM_024245, BC047273 |
71819 |
34 |
nucleotide binding mitotic cytokinesis actomyosin contractile ring assembly microtubule motor activity ATP binding nucleus nucleus nucleoplasm cytoplasm centrosome spindle cytoskeleton kinesin complex microtubule microtubule-based movement cell cycle microtubule binding microtubule binding ATPase activity midbody positive regulation of cytokinesis intercellular bridge mitotic spindle midzone assembly mitotic spindle midzone assembly cell division plus-end-directed vesicle transport along microtubule mitotic spindle Flemming body centralspindlin complex |
|
| TC0600003302.mm.2 |
Lrp6 |
low density lipoprotein receptor-related protein 6 |
6 |
-134446477 |
NM_008514, BC060704 NM_008514, BC060704 |
16974 |
224 |
gastrulation with mouth forming second somitogenesis neural tube closure neural tube closure neural tube closure negative regulation of protein phosphorylation heart looping morphogenesis of an epithelium positive regulation of mesenchymal cell proliferation pericardium morphogenesis pericardium morphogenesis axis elongation low-density lipoprotein particle receptor activity low-density lipoprotein particle receptor activity signaling receptor binding frizzled binding protein binding early endosome early endosome endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane plasma membrane caveola regulation of transcription, DNA-templated negative regulation of protein kinase activity endocytosis positive regulation of cytosolic calcium ion concentration chemical synaptic transmission chemical synaptic transmission multicellular organism development embryonic pattern specification embryonic pattern specification dorsal/ventral axis specification anterior/posterior pattern specification anterior/posterior pattern specification cell surface cell surface positive regulation of neuron projection development neural crest formation neural crest formation neural crest cell differentiation neural crest cell differentiation coreceptor activity membrane integral component of membrane Wnt signaling pathway Wnt-protein binding Wnt-protein binding kinase inhibitor activity toxin transmembrane transporter activity cerebellum morphogenesis cerebellum morphogenesis thalamus development thalamus development cerebral cortex cell migration forebrain radial glial cell differentiation forebrain generation of neurons Wnt signaling pathway involved in forebrain neuroblast division Wnt signaling pathway involved in forebrain neuroblast division neural tube development formation of radial glial scaffolds cerebral cortex development cerebral cortex development regulation of ossification embryonic limb morphogenesis embryonic limb morphogenesis forebrain development midbrain development midbrain development midbrain-hindbrain boundary development midbrain-hindbrain boundary development cytoplasmic vesicle apolipoprotein binding apolipoprotein binding negative regulation of smooth muscle cell apoptotic process limb morphogenesis limb morphogenesis embryonic forelimb morphogenesis embryonic forelimb morphogenesis embryonic hindlimb morphogenesis embryonic hindlimb morphogenesis external genitalia morphogenesis external genitalia morphogenesis post-anal tail morphogenesis post-anal tail morphogenesis cell migration involved in gastrulation regulation of cell population proliferation odontogenesis of dentin-containing tooth odontogenesis of dentin-containing tooth embryonic digit morphogenesis embryonic digit morphogenesis identical protein binding protein homodimerization activity Wnt-activated receptor activity neuronal cell body neuronal cell body positive regulation of apoptotic process synapse synapse negative regulation of fat cell differentiation positive regulation of ossification positive regulation of bone resorption positive regulation of cell cycle positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II bone remodeling bone remodeling embryonic camera-type eye morphogenesis embryonic camera-type eye morphogenesis generation of neurons skeletal system morphogenesis negative regulation of epithelial cell proliferation positive regulation of DNA-binding transcription factor activity positive regulation of DNA-binding transcription factor activity positive regulation of DNA-binding transcription factor activity response to folic acid roof of mouth development roof of mouth development convergent extension convergent extension retina morphogenesis in camera-type eye embryonic retina morphogenesis in camera-type eye embryonic retina morphogenesis in camera-type eye canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway regulation of cell development face morphogenesis face morphogenesis bone morphogenesis bone morphogenesis branching involved in mammary gland duct morphogenesis branching involved in mammary gland duct morphogenesis trachea cartilage morphogenesis trachea cartilage morphogenesis mammary placode formation mammary gland duct morphogenesis canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation cellular response to cholesterol dopaminergic neuron differentiation negative regulation of protein serine/threonine kinase activity coreceptor activity involved in Wnt signaling pathway protein localization to plasma membrane primitive streak formation primitive streak formation receptor-mediated endocytosis involved in cholesterol transport receptor-mediated endocytosis involved in cholesterol transport Wnt signaling pathway involved in somitogenesis Wnt signaling pathway involved in somitogenesis axis elongation involved in somitogenesis axis elongation involved in somitogenesis cell-cell adhesion Norrin signaling pathway Wnt-Frizzled-LRP5/6 complex Wnt signalosome negative regulation of non-canonical Wnt signaling pathway negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis negative regulation of planar cell polarity pathway involved in pericardium morphogenesis negative regulation of planar cell polarity pathway involved in neural tube closure |
04310 |
| TC0X00000166.mm.2 |
Ddx3x |
DEAD box helicase 3, X-linked |
X |
13281021 |
NM_010028, BC150862, BC172016 NM_010028, BC150862, BC172016 NM_010028, BC150862, BC172016 |
13205 |
56 |
nucleotide binding immune system process nucleic acid binding DNA binding DNA helicase activity RNA binding RNA binding RNA helicase activity RNA helicase activity mRNA binding GTPase activity helicase activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm centrosome cytosol eukaryotic translation initiation factor 3 complex plasma membrane translational initiation regulation of translation apoptotic process inflammatory response chromosome segregation gamete generation transcription factor binding poly(A) binding eukaryotic initiation factor 4E binding extrinsic apoptotic signaling pathway via death domain receptors response to virus cytoplasmic stress granule cytoplasmic stress granule RNA secondary structure unwinding positive regulation of gene expression membrane Wnt signaling pathway hydrolase activity ATPase activity nucleoside-triphosphatase activity negative regulation of translation cytosolic small ribosomal subunit cell differentiation positive regulation of cell growth negative regulation of cell growth primary miRNA processing primary miRNA processing cell leading edge negative regulation of protein-containing complex assembly translation initiation factor binding positive regulation of protein autophosphorylation positive regulation of interferon-alpha production positive regulation of interferon-beta production RNA strand annealing activity stress granule assembly stress granule assembly positive regulation of toll-like receptor 7 signaling pathway positive regulation of toll-like receptor 8 signaling pathway intracellular signal transduction RNA stem-loop binding positive regulation of translation in response to endoplasmic reticulum stress ribosome biogenesis mature ribosome assembly cell projection gamma-tubulin binding ribosomal small subunit binding positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process P granule CTPase activity positive regulation of cysteine-type endopeptidase activity involved in apoptotic process protein serine/threonine kinase activator activity positive regulation of viral genome replication innate immune response positive regulation of translation positive regulation of transcription by RNA polymerase II positive regulation of translational initiation mRNA 5'-UTR binding lipid homeostasis inflammasome complex primary miRNA binding cellular response to arsenic-containing substance cellular response to osmotic stress positive regulation of protein serine/threonine kinase activity NLRP3 inflammasome complex positive regulation of canonical Wnt signaling pathway intrinsic apoptotic signaling pathway cellular response to virus positive regulation of G1/S transition of mitotic cell cycle positive regulation of NLRP3 inflammasome complex assembly negative regulation of NIK/NF-kappaB signaling positive regulation of NIK/NF-kappaB signaling positive regulation of protein acetylation negative regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of protein K63-linked ubiquitination protein localization to cytoplasmic stress granule negative regulation of intrinsic apoptotic signaling pathway |
04622 |
| TC0X00002052.mm.2 |
Nkrf |
NF-kappaB repressing factor |
X |
-36885990 |
NM_029891, BC138828, BC138829 NM_029891, BC138828, BC138829 NM_029891, BC138828, BC138829 |
77286 |
27 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific nucleic acid binding DNA binding nucleus nucleoplasm nucleoplasm nucleolus nucleolus negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II |
|
| TC0900001042.mm.2 |
Elovl5 |
ELOVL family member 5, elongation of long chain fatty acids (yeast) |
9 |
77917364 |
NM_134255, BC022911 NM_134255, BC022911 |
68801 |
33 |
endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process fatty acid elongase activity fatty acid elongase activity membrane integral component of membrane transferase activity fatty acid elongation, saturated fatty acid sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane fatty acid elongation, monounsaturated fatty acid fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid very long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process cell projection neuronal cell body positive regulation of fatty acid biosynthetic process dendritic tree 3-oxo-arachidoyl-CoA synthase activity 3-oxo-cerotoyl-CoA synthase activity 3-oxo-lignoceronyl-CoA synthase activity |
01040 |
| TC0X00001382.mm.2 |
Prps1 |
phosphoribosyl pyrophosphate synthetase 1 |
X |
140456602 |
NM_021463, BC054772 NM_021463, BC054772 |
19139 |
35 |
nucleotide binding magnesium ion binding ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding ATP binding cytoplasm 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process purine nucleobase metabolic process purine nucleotide biosynthetic process purine nucleotide biosynthetic process AMP biosynthetic process nervous system development nucleoside metabolic process ribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process AMP binding kinase activity phosphorylation transferase activity GDP binding ribose phosphate metabolic process carbohydrate binding protein-containing complex urate biosynthetic process identical protein binding protein homodimerization activity ADP binding cellular biosynthetic process hypoxanthine biosynthetic process metal ion binding |
00030 00230 01100 |
| TC1900000529.mm.2 |
Kif11 |
kinesin family member 11 |
19 |
37376381 |
NM_010615, BC060670 NM_010615, BC060670 |
16551 |
58 |
nucleotide binding spindle pole microtubule motor activity ATP binding nucleus cytoplasm spindle cytosol cytoskeleton microtubule spindle microtubule spindle microtubule microtubule-based movement cell cycle spindle organization mitotic centrosome separation microtubule binding ATP-dependent microtubule motor activity, plus-end-directed protein kinase binding protein-containing complex regulation of mitotic centrosome separation spindle assembly cell division mitotic spindle mitotic spindle assembly mitotic spindle assembly |
|
| TC0100001351.mm.2 |
Ivns1abp |
influenza virus NS1A binding protein |
1 |
151344485, 151344497, 151344497 |
NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092 NM_001039511, NM_001039512, NM_054102, BC004092 |
117198 |
29 |
protein binding nucleus cytoplasm cytosol cytoskeleton RNA splicing response to virus negative regulation of protein ubiquitination negative regulation of intrinsic apoptotic signaling pathway |
|
| TC0800000968.mm.2 |
Syce2 |
synaptonemal complex central element protein 2 |
8 |
84872110, 84872257 |
NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 NM_001168244, NM_001168246, NM_027954, NR_031759, BC094628, BC132534 |
71846 |
31 |
synaptonemal complex central element central element protein binding nucleus nucleoplasm nucleoplasm chromosome cell cycle synaptonemal complex assembly cell division meiotic cell cycle |
|
| TC0500000732.mm.2 |
Paics |
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase |
5 |
76951301 |
NM_025939, BC018153, BC052691 NM_025939, BC018153, BC052691 NM_025939, BC018153, BC052691 |
67054 |
38 |
nucleotide binding catalytic activity phosphoribosylaminoimidazole carboxylase activity phosphoribosylaminoimidazolesuccinocarboxamide synthase activity ATP binding cytoplasm cytosol purine nucleotide biosynthetic process 'de novo' IMP biosynthetic process metabolic process lyase activity carboxy-lyase activity ligase activity identical protein binding |
00230 01100 |
| MG-1-pos-10341832_st |
|
|
|
|
|
|
|
|
|
| TC0900002369.mm.2 |
Scamp5 |
secretory carrier membrane protein 5 |
9 |
-57441326 |
NM_020270, BC018613 NM_020270, BC018613 |
56807 |
22 |
Golgi membrane positive regulation of cytokine production endosome Golgi apparatus plasma membrane exocytosis synaptic vesicle synaptic vesicle protein transport membrane integral component of membrane cell junction integral component of synaptic vesicle membrane cytoplasmic vesicle trans-Golgi network membrane trans-Golgi network membrane response to endoplasmic reticulum stress protein-containing complex binding synapse negative regulation of endocytosis positive regulation of calcium ion-dependent exocytosis recycling endosome membrane recycling endosome membrane regulation of synaptic vesicle endocytosis |
|
| TC0700004201.mm.2 |
Cdr2 |
cerebellar degeneration-related 2 |
7 |
-120957039, -120957036 |
NM_007672, BC117530, BC118511 NM_007672, BC117530, BC118511 NM_007672, BC117530, BC118511 |
12585 |
20 |
molecular_function cytoplasm biological_process |
|
| TC0400000506.mm.2 |
Anp32b |
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
4 |
46450925 |
NM_130889, BC003489, BC005628, BC093506 NM_130889, BC003489, BC005628, BC093506 NM_130889, BC003489, BC005628, BC093506 NM_130889, BC003489, BC005628, BC093506 |
67628 |
35 |
G1/S transition of mitotic cell cycle vasculature development nucleus nucleus nucleus positive regulation of cell population proliferation ventricular system development histone binding regulation of apoptotic process negative regulation of apoptotic process inner ear development roof of mouth development positive regulation of G1/S transition of mitotic cell cycle |
|
| TC0300001757.mm.2 |
Ect2 |
ect2 oncogene |
3 |
-27097221, -27097221 |
NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 NM_001177625, NM_001177626, NM_007900, BC023881, BC025565, BC032155, BC045614 |
13605 |
48 |
mitotic cytokinesis mitotic cytokinesis cell morphogenesis guanyl-nucleotide exchange factor activity GTPase activator activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytoskeleton cell-cell junction bicellular tight junction cell cortex cell cycle nervous system development protein transport nuclear body cell junction cell differentiation midbody small GTPase binding activation of protein kinase activity cleavage furrow positive regulation of cytokinesis regulation of Rho protein signal transduction intracellular signal transduction positive regulation of protein import into nucleus protein homodimerization activity positive regulation of apoptotic process positive regulation of GTPase activity positive regulation of neuron differentiation regulation of protein kinase activity protein homooligomerization cell division regulation of attachment of spindle microtubules to kinetochore cellular response to hydrogen peroxide bicellular tight junction assembly cellular response to calcium ion cellular response to ionizing radiation mitotic spindle activation of GTPase activity activation of GTPase activity centralspindlin complex regulation of cytokinesis, actomyosin contractile ring assembly |
|
| TC1600001011.mm.2 |
Itsn1 |
intersectin 1 (SH3 domain protein 1A) |
16 |
91729370, 91729370, 91729370 |
NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688 NM_001110275, NM_001110276, NM_010587, BC172688 |
16443 |
71 |
guanyl-nucleotide exchange factor activity calcium ion binding protein binding nucleus nuclear envelope cytoplasm cytoplasm endosome cytosol plasma membrane plasma membrane clathrin-coated pit clathrin-coated pit clathrin-coated pit exocytosis endocytosis small GTPase mediated signal transduction protein transport membrane endosomal transport kinase activator activity lamellipodium cell junction endocytic vesicle cytoplasmic vesicle cellular protein localization regulation of Rho protein signal transduction intracellular signal transduction presynaptic membrane cell projection neuron projection neuronal cell body dendritic spine negative regulation of neuron apoptotic process calyx of Held synapse metal ion binding synaptic vesicle endocytosis synaptic vesicle endocytosis positive regulation of protein kinase B signaling molecular adaptor activity molecular adaptor activity positive regulation of growth hormone secretion positive regulation of dendritic spine development proline-rich region binding apical dendrite intracellular vesicle intracellular vesicle presynaptic endocytic zone postsynaptic actin cytoskeleton glutamatergic synapse clathrin-dependent synaptic vesicle endocytosis regulation of modification of postsynaptic actin cytoskeleton positive regulation of caveolin-mediated endocytosis |
|
| TC0300000656.mm.2 |
Tmem154 |
transmembrane protein 154 |
3 |
84666191 |
NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175 NM_177260, BC096432, BC113174, BC113175 |
320782 |
11 |
molecular_function cellular_component biological_process membrane integral component of membrane |
|
| TC0200003697.mm.2 |
Spc25 |
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) |
2 |
-69193894 |
NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 NM_001199123, NM_001199124, NM_025565, BC027121, BC033605 |
66442 |
23 |
chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome kinetochore molecular_function nucleus chromosome cytosol cell cycle mitotic spindle organization chromosome segregation chromosome segregation Ndc80 complex Ndc80 complex cell division |
|
| TC0600002491.mm.2 |
Mat2a |
methionine adenosyltransferase II, alpha |
6 |
-72432795 |
NM_145569, BC003451, BC058360 NM_145569, BC003451, BC058360 NM_145569, BC003451, BC058360 |
232087 |
42 |
nucleotide binding methionine adenosyltransferase activity methionine adenosyltransferase activity methionine adenosyltransferase activity ATP binding cytosol cytosol S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to hormone amino acid binding transferase activity protein hexamerization response to drug identical protein binding metal ion binding methionine adenosyltransferase complex methionine adenosyltransferase complex protein heterooligomerization response to cAMP cellular response to leukemia inhibitory factor |
00270 01100 |
| TC1400001931.mm.2 |
Wdhd1 |
WD repeat and HMG-box DNA binding protein 1 |
14 |
-47240943 |
NM_172598, BC063740 NM_172598, BC063740 |
218973 |
22 |
mitotic cell cycle chromosome, centromeric region DNA binding chromatin binding chromatin binding RNA binding protein binding nucleus nucleoplasm DNA-dependent DNA replication DNA repair RNA processing regulation of chromosome organization nuclear replication fork RNA polymerase binding heterochromatin maintenance |
|
| TC0M00000011.mm.2 |
|
|
|
|
|
|
|
|
|
| TC1400001314.mm.2 |
Ipo5 |
importin 5 |
14 |
120915846, 120911193 |
NM_023579, BC052392, BC054814 NM_023579, BC052392, BC054814 NM_023579, BC052392, BC054814 |
70572 |
40 |
protein binding nucleus nucleus cytoplasm cytoplasm protein import into nucleus NLS-bearing protein import into nucleus ribosomal protein import into nucleus intracellular protein transport nuclear localization sequence binding protein transport small GTPase binding positive regulation of protein import into nucleus nuclear import signal receptor activity nuclear import signal receptor activity cellular response to amino acid stimulus |
|
| TC1100003941.mm.2 |
Kpna2 |
karyopherin (importin) alpha 2 |
11 |
-106988628 |
NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 NM_010655, BC003274, BC006720, BC082280, BC094011 |
16647 |
97 |
protein binding nucleus nucleoplasm nucleoplasm nucleoplasm cytosol cytosol protein import into nucleus NLS-bearing protein import into nucleus NLS-bearing protein import into nucleus nuclear localization sequence binding nuclear localization sequence binding cytoplasmic stress granule histone deacetylase binding nuclear import signal receptor activity nuclear import signal receptor activity repressing transcription factor binding entry of viral genome into host nucleus through nuclear pore complex via importin entry of viral genome into host nucleus through nuclear pore complex via importin extrinsic component of postsynaptic specialization membrane glutamatergic synapse postsynapse to nucleus signaling pathway positive regulation of viral life cycle positive regulation of viral life cycle |
|
| TC0X00001272.mm.2 |
|
|
|
|
NM_133196, NR_037299, BC036719 NM_133196, NR_037299, BC036719 NM_133196, NR_037299, BC036719 |
|
|
nucleic acid binding RNA binding mRNA binding nucleus nucleoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA polyadenylation mRNA processing nuclear body mRNA 3'-end processing cleavage body pre-mRNA cleavage required for polyadenylation |
|
| TC0200000245.mm.2 |
Mrc1 |
mannose receptor, C type 1 |
2 |
14229413 |
NM_008625, BC141338 NM_008625, BC141338 |
17533 |
108 |
transmembrane signaling receptor activity protein binding mannose binding endosome plasma membrane plasma membrane plasma membrane endocytosis receptor-mediated endocytosis receptor-mediated endocytosis cell surface endosome membrane membrane integral component of membrane carbohydrate binding signaling receptor activity cargo receptor activity cellular response to lipopolysaccharide cellular response to interferon-gamma cellular response to interleukin-4 |
04145 |
| TC0600002044.mm.2 |
Slc35b4 |
solute carrier family 35, member B4 |
6 |
-34155878 |
NM_021435, BC033512 NM_021435, BC033512 |
58246 |
19 |
UDP-N-acetylglucosamine transmembrane transporter activity UDP-N-acetylglucosamine transmembrane transporter activity UDP-xylose transmembrane transporter activity UDP-xylose transmembrane transporter activity endoplasmic reticulum Golgi apparatus regulation of gluconeogenesis carbohydrate transport UDP-xylose transmembrane transport membrane integral component of membrane transmembrane transporter activity integral component of Golgi membrane integral component of endoplasmic reticulum membrane transmembrane transport UDP-N-acetylglucosamine transmembrane transport |
|
| TC1900000560.mm.2 |
Hells |
helicase, lymphoid specific |
19 |
38930989 |
NM_008234, BC100394 NM_008234, BC100394 |
15201 |
65 |
nucleotide binding chromosome, centromeric region urogenital system development chromatin binding chromatin binding helicase activity protein binding ATP binding nucleus nucleus pericentric heterochromatin pericentric heterochromatin DNA methylation DNA methylation chromatin silencing DNA methylation-dependent heterochromatin assembly DNA methylation-dependent heterochromatin assembly cell cycle multicellular organism development maintenance of DNA methylation maintenance of DNA methylation hydrolase activity lymphocyte differentiation pericentric heterochromatin assembly pericentric heterochromatin assembly negative regulation of apoptotic process lymphocyte proliferation lymphocyte proliferation cell division cellular response to leukemia inhibitory factor negative regulation of intrinsic apoptotic signaling pathway |
|
| TC1500000614.mm.2 |
Rpl8 |
ribosomal protein L8 |
15 |
76904070 |
NM_012053, BC043017 NM_012053, BC043017 |
26961 |
28 |
cytoplasmic translation cytoplasmic translation RNA binding structural constituent of ribosome protein binding cytoplasm ribosome translation postsynaptic density large ribosomal subunit rRNA binding cytosolic large ribosomal subunit cytosolic large ribosomal subunit polysomal ribosome synapse synapse postsynapse |
03010 |
| MG-1-pos-10342684_st |
|
|
|
|
|
|
|
|
|
| TC1200001939.mm.2 |
Sgpp1 |
sphingosine-1-phosphate phosphatase 1 |
12 |
-75714247 |
NM_030750, BC037592 NM_030750, BC037592 |
81535 |
31 |
endoplasmic reticulum endoplasmic reticulum membrane plasma membrane sphingolipid metabolic process sphinganine-1-phosphate metabolic process sphingosine metabolic process sphingosine metabolic process membrane membrane integral component of membrane hydrolase activity ER to Golgi ceramide transport sphingosine-1-phosphate phosphatase activity sphingosine-1-phosphate phosphatase activity sphingosine-1-phosphate phosphatase activity regulation of keratinocyte differentiation regulation of epidermis development phospholipid dephosphorylation extrinsic apoptotic signaling pathway intrinsic apoptotic signaling pathway |
00600 |
| TC0100002411.mm.2 |
Wdr12 |
WD repeat domain 12 |
1 |
-60076867, -60076867, -60076867 |
NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 NM_001199060, NM_001199061, NM_021312, BC004748, BC052386, BC096651 |
57750 |
23 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) protein binding nucleus nucleoplasm nucleolus rRNA processing Notch signaling pathway preribosome, large subunit precursor preribosome, large subunit precursor ribosome biogenesis regulation of cell cycle PeBoW complex PeBoW complex |
|
| TC0600001813.mm.2 |
Slc25a13 |
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13 |
6 |
-6041217 |
NM_001177572, NM_015829, BC016571 NM_001177572, NM_015829, BC016571 NM_001177572, NM_015829, BC016571 |
50799 |
49 |
L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity L-glutamate transmembrane transporter activity calcium ion binding mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane ATP biosynthetic process transport L-aspartate transmembrane transporter activity L-aspartate transmembrane transporter activity aspartate transmembrane transport aspartate transmembrane transport aspartate transmembrane transport L-glutamate transmembrane transport L-glutamate transmembrane transport membrane integral component of membrane transmembrane transporter activity identical protein binding malate-aspartate shuttle malate-aspartate shuttle malate-aspartate shuttle cellular respiration metal ion binding response to calcium ion transmembrane transport |
|
| TC0800002927.mm.2 |
Sf3b3 |
splicing factor 3b, subunit 3 |
8 |
-110810491 |
NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 NM_133953, BC011412, BC042580, BC139015, BC139016 |
101943 |
28 |
mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding nucleus nucleus nucleoplasm spliceosomal complex U2 snRNP U12-type spliceosomal complex nucleolus mRNA processing RNA splicing U2 snRNA binding negative regulation of protein catabolic process protein-containing complex binding U2-type precatalytic spliceosome catalytic step 2 spliceosome |
03040 |
| TC1100003401.mm.2 |
Ccl3 |
chemokine (C-C motif) ligand 3 |
11 |
-83647842 |
NM_011337, BC111443 NM_011337, BC111443 |
20302 |
260 |
monocyte chemotaxis cytokine activity protein binding extracellular region extracellular space extracellular space chemotaxis inflammatory response immune response G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity chemokine activity regulation of cell shape neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis positive regulation of interleukin-1 beta production positive regulation of tumor necrosis factor production positive regulation of neuron apoptotic process positive regulation of GTPase activity astrocyte cell migration positive regulation of osteoclast differentiation positive regulation of transcription by RNA polymerase II CCR chemokine receptor binding macrophage chemotaxis lymphocyte chemotaxis positive regulation of inflammatory response chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor |
04060 04062 04620 05142 05323 |
| TC0700000896.mm.2 |
Nav2 |
neuron navigator 2 |
7 |
49246188, 48959072 |
NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112 NM_001111016, NM_175272, XR_105111, XR_105112 |
78286 |
34 |
regulation of systemic arterial blood pressure by baroreceptor feedback interstitial matrix nucleoplasm nervous system development nervous system development sensory perception of sound sensory perception of smell locomotory behavior heparin binding optic nerve development glossopharyngeal nerve development vagus nerve development cerebellar cortex development extracellular matrix 3'-5' DNA helicase activity |
|
| TC1100004183.mm.2 |
Sgsh |
N-sulfoglucosamine sulfohydrolase (sulfamidase) |
11 |
-119343488 |
NM_018822, BC130268 NM_018822, BC130268 |
27029 |
46 |
protein binding glycosaminoglycan binding lysosome lysosome glycosaminoglycan catabolic process glycosaminoglycan catabolic process N-acetylglucosamine-6-sulfatase activity sulfuric ester hydrolase activity sulfuric ester hydrolase activity N-sulfoglucosamine sulfohydrolase activity N-sulfoglucosamine sulfohydrolase activity heparan sulfate proteoglycan catabolic process heparan sulfate proteoglycan catabolic process heparan sulfate proteoglycan metabolic process |
00531 01100 04142 |
| TC0200001053.mm.2 |
Map3k20 |
mitogen-activated protein kinase kinase kinase 20 |
2 |
72285700, 72285700, 72285636 |
NM_001164791, NM_023057, NM_178084, BC023718 NM_001164791, NM_023057, NM_178084, BC023718 NM_001164791, NM_023057, NM_178084, BC023718 NM_001164791, NM_023057, NM_178084, BC023718 |
65964 |
25 |
DNA damage checkpoint nucleotide binding magnesium ion binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity MAP kinase kinase kinase activity MAP kinase kinase kinase activity ATP binding ATP binding nucleus cytoplasm cytoplasm cytosol protein phosphorylation protein phosphorylation cytoskeleton organization cell cycle cell cycle arrest activation of JUN kinase activity kinase activity phosphorylation transferase activity intracellular signal transduction embryonic digit morphogenesis embryonic digit morphogenesis positive regulation of apoptotic process metal ion binding stress-activated MAPK cascade limb development limb development cellular response to gamma radiation positive regulation of mitotic DNA damage checkpoint |
04010 04530 |
| MG-1-pos-10343802_st |
|
|
|
|
|
|
|
|
|
| TC0400001395.mm.2 |
Pabpc4 |
poly(A) binding protein, cytoplasmic 4 |
4 |
123282910 |
NM_130881, NM_148917, BC003283, BC010345, BC056432 NM_130881, NM_148917, BC003283, BC010345, BC056432 NM_130881, NM_148917, BC003283, BC010345, BC056432 NM_130881, NM_148917, BC003283, BC010345, BC056432 NM_130881, NM_148917, BC003283, BC010345, BC056432 |
230721 |
21 |
RNA binding mRNA binding mRNA 3'-UTR binding nucleus nucleus cytoplasm cytosol cytosol poly(A) binding poly(A) binding poly(U) RNA binding poly(U) RNA binding cytoplasmic stress granule cytoplasmic stress granule regulation of mRNA stability myeloid cell development ribonucleoprotein complex ribonucleoprotein complex |
03013 03015 03018 |
| TC1100001049.mm.2 |
Mettl16 |
methyltransferase like 16 |
11 |
74770862 |
NM_026197, BC049897, BC054724 NM_026197, BC049897, BC054724 NM_026197, BC049897, BC054724 |
67493 |
23 |
RNA methylation mRNA (N6-adenosine)-methyltransferase activity mRNA (N6-adenosine)-methyltransferase activity RNA binding nucleus nucleus cytoplasm mRNA catabolic process S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process methyltransferase activity posttranscriptional regulation of gene expression posttranscriptional regulation of gene expression transferase activity U6 snRNA 3'-end binding methylation RNA stem-loop binding 23S rRNA (adenine(1618)-N(6))-methyltransferase activity mRNA destabilization rRNA base methylation mRNA methylation mRNA methylation U6 snRNA (adenine-(43)-N(6))-methyltransferase activity snRNA (adenine-N6)-methylation negative regulation of 3'-UTR-mediated mRNA stabilization |
|
| TC0800001116.mm.2 |
Arl2bp |
ADP-ribosylation factor-like 2 binding protein |
8 |
94667090, 94666599 |
NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708 NM_024191, NM_024269, BC002131, BC024708 |
107566 |
23 |
transcription coactivator activity protein binding nucleus cytoplasm mitochondrion mitochondrial intermembrane space mitochondrial intermembrane space centrosome cytoskeleton cilium midbody GTPase regulator activity positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein cell projection maintenance of protein location in nucleus maintenance of protein location in nucleus |
|
| TC0100002576.mm.2 |
Tns1 |
tensin 1 |
1 |
-73910231 |
NM_001289895, NM_027884 NM_001289895, NM_027884 |
21961 |
27 |
actin binding focal adhesion focal adhesion cell-substrate junction assembly fibroblast migration cell-substrate junction |
|
| TC0100000682.mm.2 |
|
|
|
|
NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 NM_001001981, NM_001033606, NM_001136222, NM_001136226, NM_028817, BC031529, BC141102 |
|
|
nucleotide binding long-chain fatty acid metabolic process long-chain fatty acid metabolic process catalytic activity long-chain fatty acid-CoA ligase activity long-chain fatty acid-CoA ligase activity ATP binding nucleus nucleolus nucleolus mitochondrion mitochondrial outer membrane peroxisome endoplasmic reticulum endoplasmic reticulum Golgi apparatus lipid droplet lipid droplet cytosol plasma membrane rRNA processing lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process multicellular organism development spermatogenesis membrane integral component of membrane ligase activity protein kinase binding protein domain specific binding cell differentiation neuron differentiation small-subunit processome very-low-density lipoprotein particle assembly long-chain fatty-acyl-CoA metabolic process ribosome biogenesis positive regulation of Golgi to plasma membrane protein transport intracellular membrane-bounded organelle long-chain fatty acid import into cell arachidonate-CoA ligase activity perinuclear region of cytoplasm positive regulation of secretion meiotic cell cycle decanoate-CoA ligase activity positive regulation of phosphatidylcholine biosynthetic process |
|
| TC0900001652.mm.2 |
Kif15 |
kinesin family member 15 |
9 |
122951080 |
NM_010620, BC060710 NM_010620, BC060710 |
209737 |
26 |
nucleotide binding microtubule motor activity ATP binding cytoplasm cytoskeleton kinesin complex microtubule microtubule-based movement microtubule binding ATPase activity |
|
| TC0800000096.mm.2 |
Arhgef7 |
Rho guanine nucleotide exchange factor (GEF7) |
8 |
11758364, 11728057, 11779283, 11728057, 11758364 |
NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838 NM_001113517, NM_001113518, NM_017402, BC044838 |
54126 |
81 |
storage vacuole hematopoietic progenitor cell differentiation guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm cytosol plasma membrane focal adhesion Golgi organization small GTPase mediated signal transduction nervous system development protein kinase binding protein kinase binding lamellipodium lamellipodium assembly cell junction growth cone small GTPase binding positive regulation of protein binding protein-containing complex regulation of Rho protein signal transduction intracellular signal transduction cell projection neuron projection neuronal cell body positive regulation of apoptotic process positive regulation of GTPase activity positive regulation of GTPase activity positive regulation of GTPase activity astrocyte cell migration positive regulation of growth hormone secretion postsynaptic actin cytoskeleton organization GABA-ergic synapse presynaptic actin cytoskeleton organization regulation of GTP binding |
04810 |
| MG-1-pos-10339670_st |
|
|
|
|
|
|
|
|
|
| TC1500001937.mm.2 |
Snu13 |
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5) |
15 |
-82041344 |
NM_011482, BC026755, BC054450, BC083315 NM_011482, BC026755, BC054450, BC083315 NM_011482, BC026755, BC054450, BC083315 NM_011482, BC026755, BC054450, BC083315 |
20826 |
26 |
mRNA splicing, via spliceosome mRNA splicing, via spliceosome maturation of LSU-rRNA box C/D snoRNP assembly dense fibrillar component RNA binding nucleus spliceosomal complex U4atac snRNP nucleolus plasma membrane mRNA processing single fertilization RNA splicing maturation of SSU-rRNA snoRNA binding U4 snRNA binding U4atac snRNA binding box C/D RNP complex box C/D RNP complex box C/D RNP complex small-subunit processome protein-containing complex U3 snoRNA binding box C/D RNA binding box C/D RNA binding ribosome biogenesis U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex ATPase binding U2-type precatalytic spliceosome precatalytic spliceosome ribonucleoprotein complex |
03008 03040 |
| TC1400000179.mm.2 |
Adk |
adenosine kinase |
14 |
21076151, 21052573 |
NM_001243041, NM_134079, BC009659 NM_001243041, NM_134079, BC009659 NM_001243041, NM_134079, BC009659 |
11534 |
58 |
nucleotide binding adenosine kinase activity adenosine kinase activity adenosine kinase activity ATP binding nucleus nucleus nucleus nucleoplasm cytoplasm cytosol cytosol cytosol plasma membrane purine ribonucleoside salvage dATP biosynthetic process positive regulation of cardiac muscle hypertrophy kinase activity transferase activity phosphotransferase activity, alcohol group as acceptor positive regulation of T cell proliferation type B pancreatic cell proliferation adenosine metabolic process metal ion binding |
00230 01100 |
| TC0500001576.mm.2 |
Tbl2 |
transducin (beta)-like 2 |
5 |
135149685 |
NM_013763, BC039273, BC048185 NM_013763, BC039273, BC048185 NM_013763, BC039273, BC048185 |
27368 |
25 |
endoplasmic reticulum protein kinase binding endoplasmic reticulum unfolded protein response translation initiation factor binding cellular response to glucose starvation phosphoprotein binding cellular response to hypoxia |
|
| TC1100000573.mm.2 |
Nhp2 |
NHP2 ribonucleoprotein |
11 |
51619772 |
NM_026631, BC024944 NM_026631, BC024944 |
52530 |
29 |
cleavage involved in rRNA processing maturation of LSU-rRNA RNA binding RNA binding protein binding nucleus telomerase holoenzyme complex nucleolus rRNA processing telomere maintenance via telomerase rRNA pseudouridine synthesis snRNA pseudouridine synthesis box H/ACA snoRNP complex box H/ACA snoRNP complex box H/ACA snoRNA binding box H/ACA snoRNA binding ribosome biogenesis telomerase RNA binding box H/ACA telomerase RNP complex |
03008 |
| TC0500002059.mm.2 |
Pus7 |
pseudouridylate synthase 7 |
5 |
-23740164, -23740164 |
NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 NM_001289780, NM_001289781, NM_178403, BC008544, BC138533, BC145316 |
78697 |
18 |
pseudouridine synthesis RNA binding nucleus nucleus tRNA processing RNA modification pseudouridine synthase activity pseudouridine synthase activity isomerase activity negative regulation of translation enzyme binding tRNA pseudouridine synthesis regulation of hematopoietic stem cell differentiation mRNA pseudouridine synthesis regulation of mesoderm development |
|
| TC0700000383.mm.2 |
Plaur |
plasminogen activator, urokinase receptor |
7 |
24462482 |
NM_011113, BC160226 NM_011113, BC160226 |
18793 |
190 |
positive regulation of protein phosphorylation signaling receptor binding protein binding extracellular region plasma membrane plasma membrane integral component of plasma membrane cell surface membrane enzyme binding protein domain specific binding regulation of proteolysis urokinase plasminogen activator receptor activity anchored component of membrane positive regulation of homotypic cell-cell adhesion urokinase plasminogen activator signaling pathway negative regulation of apoptotic process positive regulation of DNA binding positive regulation of epidermal growth factor receptor signaling pathway mesenchymal cell differentiation epithelial cell differentiation involved in prostate gland development positive regulation of release of cytochrome c from mitochondria negative regulation of intrinsic apoptotic signaling pathway negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
04610 |
| TC1600001379.mm.2 |
Etv5 |
ets variant 5 |
16 |
-22381312, -22381312 |
NM_023794, BC034680 NM_023794, BC034680 |
104156 |
283 |
negative regulation of transcription by RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II neuromuscular synaptic transmission locomotory behavior cell differentiation cellular response to oxidative stress sequence-specific DNA binding positive regulation of neuron differentiation positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II male germ-line stem cell asymmetric division regulation of synapse organization positive regulation of glial cell proliferation regulation of branching involved in mammary gland duct morphogenesis skeletal muscle acetylcholine-gated channel clustering sequence-specific double-stranded DNA binding |
|
| TC1500001896.mm.2 |
Rpl3 |
ribosomal protein L3 |
15 |
-80077780 |
NM_013762, BC009655, BC083134, BC094059, BC158039 NM_013762, BC009655, BC083134, BC094059, BC158039 NM_013762, BC009655, BC083134, BC094059, BC158039 NM_013762, BC009655, BC083134, BC094059, BC158039 NM_013762, BC009655, BC083134, BC094059, BC158039 |
27367 |
42 |
ribosomal large subunit assembly RNA binding structural constituent of ribosome intracellular anatomical structure nucleus nucleolus cytoplasm cytosol ribosome translation 5S rRNA binding cytosolic large ribosomal subunit cytosolic large ribosomal subunit protein-containing complex synapse cellular response to interleukin-4 |
03010 |
| TC1600001143.mm.2 |
Ubald1 |
UBA-like domain containing 1 |
16 |
-4874778 |
NM_145359, BC013706, BC064081 NM_145359, BC013706, BC064081 NM_145359, BC013706, BC064081 |
207740 |
15 |
molecular_function cellular_component biological_process |
|
| TC0400000464.mm.2 |
Melk |
maternal embryonic leucine zipper kinase |
4 |
44300916 |
NM_010790, BC085276 NM_010790, BC085276 |
17279 |
40 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity calcium ion binding protein binding ATP binding nucleus cytoplasm cytoplasm plasma membrane cell cortex protein phosphorylation apoptotic process cell cycle cell population proliferation lipid binding intrinsic apoptotic signaling pathway in response to oxidative stress membrane kinase activity phosphorylation transferase activity intracellular signal transduction positive regulation of apoptotic process protein autophosphorylation neural precursor cell proliferation |
|
| TC1400001920.mm.2 |
Cnih1 |
cornichon family AMPA receptor auxiliary protein 1 |
14 |
-46775567 |
NM_009919, BC034868 NM_009919, BC034868 |
12793 |
18 |
molecular_function cellular_component endoplasmic reticulum Golgi apparatus biological_process membrane integral component of membrane vesicle-mediated transport |
|
| TC0400001667.mm.2 |
Cnr2 |
cannabinoid receptor 2 (macrophage) |
4 |
135911679, 135895188 |
NM_009924, BC024052 NM_009924, BC024052 |
12802 |
286 |
G protein-coupled receptor activity G protein-coupled receptor activity cannabinoid receptor activity cannabinoid receptor activity protein binding cytoplasm endoplasmic reticulum plasma membrane inflammatory response signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway membrane integral component of membrane regulation of metabolic process sensory perception of pain dendrite leukocyte chemotaxis extrinsic component of cytoplasmic side of plasma membrane negative regulation of synaptic transmission, GABAergic response to lipopolysaccharide negative regulation of mast cell activation cannabinoid signaling pathway cell projection neuron projection neuronal cell body negative regulation of action potential negative regulation of inflammatory response negative regulation of nitric-oxide synthase activity |
04080 |
| TC1400002215.mm.2 |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
14 |
-63145150, -63145150 |
NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302 NM_010191, BC054722, BC138301, BC138302 |
14137 |
44 |
catalytic activity farnesyl-diphosphate farnesyltransferase activity farnesyl-diphosphate farnesyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process ergosterol biosynthetic process metabolic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process lipid biosynthetic process biosynthetic process membrane integral component of membrane sterol biosynthetic process transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups intracellular membrane-bounded organelle farnesyl diphosphate metabolic process farnesyl diphosphate metabolic process metal ion binding squalene synthase activity |
00100 01100 |
| TC0400001856.mm.2 |
Dhrs3 |
dehydrogenase/reductase (SDR family) member 3 |
4 |
144893136, 144892826, 144893076 |
NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 NM_001172424, NM_011303, BC008980, BC010972, BC013540 |
20148 |
30 |
retinoid metabolic process retinoid metabolic process outflow tract morphogenesis retinol dehydrogenase activity retinol dehydrogenase activity lipid droplet membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor regulation of ossification retinol metabolic process regulation of retinoic acid receptor signaling pathway negative regulation of retinoic acid receptor signaling pathway NADP-retinol dehydrogenase activity roof of mouth development bone morphogenesis cardiac septum morphogenesis |
00830 01100 |
| TC0100003500.mm.2 |
Nuf2 |
NUF2, NDC80 kinetochore complex component |
1 |
-169497933 |
NM_023284, BC020026 NM_023284, BC020026 |
66977 |
22 |
chromosome, centromeric region kinetochore condensed nuclear chromosome kinetochore nucleus nucleoplasm chromosome cytosol cell cycle mitotic spindle organization attachment of spindle microtubules to kinetochore Ndc80 complex Ndc80 complex protein-containing complex binding meiotic chromosome segregation cell division attachment of mitotic spindle microtubules to kinetochore kinetochore organization |
|
| TC1500000053.mm.2 |
Nup155 |
nucleoporin 155 |
15 |
8109312 |
NM_133227, BC050919 NM_133227, BC050919 |
170762 |
28 |
transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear envelope nuclear pore cytoplasm RNA export from nucleus mRNA export from nucleus protein import into nucleus protein import into nucleus nucleocytoplasmic transport nuclear envelope organization protein transport membrane structural constituent of nuclear pore nuclear membrane protein localization to nuclear inner membrane nuclear pore inner ring mRNA transport atrial cardiac muscle cell action potential |
03013 |
| TC1100002224.mm.2 |
Fignl1 |
fidgetin-like 1 |
11 |
-11800287 |
NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 NM_001163359, NM_001163360, NM_021891, BC051942, BC052415 |
60530 |
23 |
nucleotide binding nuclear chromosome osteoblast differentiation ATP binding nucleus nucleus cytoplasm male meiotic nuclear division microtubule-severing ATPase activity regulation of double-strand break repair via homologous recombination hydrolase activity ATPase activity cytoplasmic microtubule organization osteoblast proliferation negative regulation of apoptotic process metal ion binding perinuclear region of cytoplasm regulation of cell cycle cellular response to ionizing radiation negative regulation of intrinsic apoptotic signaling pathway |
|
| TC0900000255.mm.2 |
Ncapd3 |
non-SMC condensin II complex, subunit D3 |
9 |
27030164, 27060415 |
NM_178113, BC048190 NM_178113, BC048190 |
78658 |
20 |
condensed chromosome kinetochore condensed chromosome, centromeric region condensed chromosome condensin complex condensin complex condensin complex chromatin binding nucleus nucleoplasm pericentric heterochromatin cell cycle mitotic chromosome condensation mitotic chromosome condensation meiotic chromosome condensation chromosome condensation methylated histone binding histone binding germinal vesicle cell division meiotic chromosome separation |
|
| TC1400001174.mm.2 |
Uchl3 |
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
14 |
101653966 |
NM_016723, BC048481 NM_016723, BC048481 |
50933 |
43 |
thiol-dependent ubiquitin-specific protease activity thiol-dependent ubiquitin-specific protease activity intracellular anatomical structure nucleoplasm cytoplasm cytosol proteolysis ubiquitin-dependent protein catabolic process adult walking behavior peptidase activity peptidase activity cysteine-type peptidase activity protein deubiquitination protein deubiquitination protein deubiquitination protein deubiquitination hydrolase activity protein catabolic process protein catabolic process cellular response to insulin stimulus eating behavior ubiquitin binding positive regulation of fat cell differentiation retina development in camera-type eye ubiquitinyl hydrolase activity |
|
| TC0600001427.mm.2 |
Phb2 |
prohibitin 2 |
6 |
124712288 |
NM_007531, BC145875 NM_007531, BC145875 |
12034 |
81 |
mitophagy mitophagy immunoglobulin production protein binding nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane mitochondrial inner membrane plasma membrane protein import into nucleus mitochondrion organization mitochondrion organization sister chromatid cohesion activation of phospholipase C activity protein C-terminus binding cell surface cell surface postsynaptic density membrane nuclear matrix cell migration CD40 signaling pathway axon positive regulation of exit from mitosis protein-containing complex negative regulation of intracellular estrogen receptor signaling pathway negative regulation of intracellular estrogen receptor signaling pathway amide binding negative regulation of mammary gland epithelial cell proliferation mitochondrial prohibitin complex induction by virus of host autophagy RIG-I signaling pathway B cell activation identical protein binding protein homodimerization activity negative regulation of apoptotic process negative regulation of DNA-binding transcription factor activity negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated sphingolipid binding sphingolipid binding protein heterodimerization activity protein N-terminus binding presynaptic active zone protein stabilization positive regulation of DNA-binding transcription factor activity mammary gland branching involved in thelarche mammary gland alveolus development regulation of branching involved in mammary gland duct morphogenesis positive regulation of ERK1 and ERK2 cascade cell periphery inner mitochondrial membrane protein complex glutamatergic synapse GABA-ergic synapse antiviral innate immune response regulation of cardiolipin metabolic process positive regulation of NIK/NF-kappaB signaling positive regulation of cell cycle G1/S phase transition regulation of cytochrome-c oxidase activity regulation of cytochrome-c oxidase activity activation of protein kinase C activity |
|
| TC0100003877.mm.2 |
Poglut2 |
protein O-glucosyltransferase 2 |
1 |
-44106545 |
NM_023645, BC023141 NM_023645, BC023141 |
72050 |
23 |
nucleoplasm endoplasmic reticulum endoplasmic reticulum lumen cytosol endomembrane system transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine UDP-glucosyltransferase activity UDP-xylosyltransferase activity glucosyltransferase activity |
|
| TC1400000910.mm.2 |
Pinx1 |
PIN2/TERF1 interacting, telomerase inhibitor 1 |
14 |
63860311 |
NM_028228, BC115636 NM_028228, BC115636 |
72400 |
17 |
nuclear chromosome chromosome, centromeric region kinetochore chromosome, telomeric region nucleic acid binding nucleus nucleoplasm chromosome nucleolus mitochondrion spindle telomere maintenance via telomerase mitotic metaphase plate congression telomerase inhibitor activity negative regulation of G2/M transition of mitotic cell cycle negative regulation of protein ubiquitination regulation of protein stability negative regulation of telomere maintenance via telomerase protein-containing complex binding negative regulation of telomerase activity telomerase RNA binding protein localization to chromosome, telomeric region protein localization to nucleolus positive regulation of telomeric DNA binding positive regulation of protein localization to nucleolus |
|
| TC1300000173.mm.2 |
H2ac13 |
H2A clustered histone 13 |
13 |
21716411 |
NM_178182, BC099406 NM_178182, BC099406 |
319191 |
16 |
DNA binding nucleus chromatin silencing negative regulation of cell population proliferation |
05322 |
| TC1500001973.mm.2 |
Pacsin2 |
protein kinase C and casein kinase substrate in neurons 2 |
15 |
-83375606, -83375606, -83375606 |
NM_001159509, NM_001159510, NM_011862, BC023502 NM_001159509, NM_001159510, NM_011862, BC023502 NM_001159509, NM_001159510, NM_011862, BC023502 NM_001159509, NM_001159510, NM_011862, BC023502 |
23970 |
42 |
protein binding phospholipid binding cytoplasm cytoplasm endosome cytosol cytosol cytoskeleton plasma membrane plasma membrane caveola caveola cell-cell junction endocytosis cytoskeleton organization signal transduction cytoskeletal protein binding lipid binding membrane nuclear speck extrinsic component of membrane actin cytoskeleton organization regulation of endocytosis cytoplasmic vesicle protein localization to endosome identical protein binding cell projection intracellular membrane-bounded organelle negative regulation of endocytosis cell projection morphogenesis modulation of chemical synaptic transmission modulation of chemical synaptic transmission recycling endosome membrane phosphatidic acid binding caveola assembly caveolin-mediated endocytosis plasma membrane tubulation plasma membrane tubulation plasma membrane tubulation glutamatergic synapse glutamatergic synapse |
|
| TC1100003817.mm.2 |
Dusp3 |
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) |
11 |
-101971143 |
NM_028207, BC016269 NM_028207, BC016269 |
72349 |
39 |
inactivation of MAPK activity in utero embryonic development immunological synapse phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus nucleoplasm cytosol cytosol protein dephosphorylation cytoskeletal protein binding protein tyrosine/serine/threonine phosphatase activity protein tyrosine/serine/threonine phosphatase activity dephosphorylation hydrolase activity phosphatase activity protein kinase binding negative regulation of cell migration receptor tyrosine kinase binding MAP kinase phosphatase activity MAP kinase phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation negative regulation of epidermal growth factor receptor signaling pathway negative regulation of MAPK cascade positive regulation of mitotic cell cycle positive regulation of mitotic cell cycle negative regulation of JNK cascade negative regulation of JNK cascade negative regulation of T cell receptor signaling pathway negative regulation of T cell receptor signaling pathway negative regulation of T cell activation negative regulation of T cell activation negative regulation of chemotaxis regulation of focal adhesion assembly regulation of focal adhesion assembly negative regulation of ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade cellular response to epidermal growth factor stimulus cellular response to epidermal growth factor stimulus positive regulation of focal adhesion disassembly peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity protein tyrosine kinase binding |
04010 |
| TC0800001258.mm.2 |
Utp4 |
UTP4 small subunit processome component |
8 |
106893639 |
NM_011574, BC027399, BC068113 NM_011574, BC027399, BC068113 NM_011574, BC027399, BC068113 |
21771 |
28 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) fibrillar center nucleus chromosome nucleolus regulation of transcription, DNA-templated rRNA processing maturation of SSU-rRNA 90S preribosome small-subunit processome t-UTP complex t-UTP complex ribosome biogenesis |
03008 |
| TC0700002950.mm.2 |
Cd33 |
CD33 antigen |
7 |
-43527455 |
NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33 NM_001111058, NM_021293, BC132379, CD33 |
12489 |
24 |
plasma membrane cell adhesion external side of plasma membrane membrane integral component of membrane carbohydrate binding sialic acid binding |
04640 |
| TC0200005349.mm.2 |
|
|
|
|
NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process |
|
| TC1100003221.mm.2 |
Rpa1 |
replication protein A1 |
11 |
-75300258 |
NM_001164223, NM_026653, BC019119 NM_001164223, NM_026653, BC019119 NM_001164223, NM_026653, BC019119 |
68275 |
73 |
telomere maintenance double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination condensed chromosome condensed nuclear chromosome lateral element male germ cell nucleus in utero embryonic development nucleic acid binding DNA binding chromatin binding damaged DNA binding damaged DNA binding single-stranded DNA binding nucleus nucleus nucleoplasm nucleoplasm DNA replication factor A complex DNA replication factor A complex DNA replication DNA unwinding involved in DNA replication DNA repair base-excision repair nucleotide-excision repair nucleotide-excision repair mismatch repair DNA recombination cellular response to DNA damage stimulus telomere maintenance via telomerase positive regulation of cell population proliferation PML body hemopoiesis protein localization to chromosome single-stranded telomeric DNA binding metal ion binding homeostasis of number of cells within a tissue chromosome organization meiotic cell cycle meiotic cell cycle site of DNA damage G-rich strand telomeric DNA binding |
03030 03420 03430 03440 |
| TC0200003267.mm.2 |
Dolk |
dolichol kinase |
2 |
-30284228 |
NM_177648, BC026973 NM_177648, BC026973 |
227697 |
16 |
dolichol kinase activity dolichol kinase activity endoplasmic reticulum membrane integral component of membrane kinase activity phosphorylation transferase activity integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane dolichyl monophosphate biosynthetic process dolichyl monophosphate biosynthetic process |
00510 01100 |
| TC0100001844.mm.2 |
Pacc1 |
proton activated chloride channel 1 |
1 |
191325901 |
NM_025864, BC027151 NM_025864, BC027151 |
66950 |
15 |
chloride channel activity plasma membrane integral component of plasma membrane ion transport chloride transport chloride transport membrane integral component of membrane chloride channel complex pH-gated chloride channel activity pH-gated chloride channel activity |
|
| TC1100001741.mm.2 |
Mettl2 |
methyltransferase like 2 |
11 |
105126424 |
NM_172567, BC089591 NM_172567, BC089591 |
52686 |
23 |
cellular_component tRNA processing methyltransferase activity transferase activity tRNA methylation tRNA methylation methylation tRNA (cytosine-3-)-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity |
00340 00350 |
| TC0600001443.mm.2 |
Lpar5 |
lysophosphatidic acid receptor 5 |
6 |
125067919, 125071334 |
NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528 NM_001163268, NM_001163269, BC116702, BC117528 |
381810 |
39 |
G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane integral component of membrane positive regulation of CREB transcription factor activity positive regulation of CREB transcription factor activity behavioral response to pain behavioral response to pain |
|
| TC0500000494.mm.2 |
Ncapg |
non-SMC condensin I complex, subunit G |
5 |
45669924 |
NM_019438, BC137834, BC144960 NM_019438, BC137834, BC144960 NM_019438, BC137834, BC144960 |
54392 |
26 |
condensed chromosome, centromeric region condensed chromosome condensed chromosome condensin complex condensin complex condensin complex molecular_function cytoplasm cytoplasm mitotic chromosome condensation mitotic chromosome condensation |
|
| TC0700000421.mm.2 |
Exosc5 |
exosome component 5 |
7 |
25659152 |
NM_138586, NR_104358, BC034358 NM_138586, NR_104358, BC034358 NM_138586, NR_104358, BC034358 |
27998 |
25 |
nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) exosome (RNase complex) molecular_function RNA binding nucleoplasm nucleolus nucleolus cytoplasm rRNA processing RNA catabolic process rRNA catabolic process nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' U4 snRNA 3'-end processing transcriptionally active chromatin exonucleolytic catabolism of deadenylated mRNA DNA deamination defense response to virus nuclear mRNA surveillance polyadenylation-dependent snoRNA 3'-end processing |
03018 |
| TC1600000480.mm.2 |
Itgb5 |
integrin beta 5 |
16 |
33829664 |
NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246 NM_001145884, NM_010580, BC046280, BC058246 |
16419 |
91 |
signaling receptor binding integrin binding integrin binding protein binding plasma membrane focal adhesion focal adhesion cell adhesion cell-matrix adhesion cell-matrix adhesion transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway integrin complex cell surface cell surface membrane integral component of membrane cell migration cell leading edge cell adhesion mediated by integrin integrin alphav-beta5 complex integrin alphav-beta5 complex signaling receptor activity stress fiber assembly stress fiber assembly receptor complex epithelial cell-cell adhesion glutamatergic synapse integral component of synaptic membrane |
04145 04510 04512 04810 05410 05412 05414 |
| MG-1-pos-10338463_st |
|
|
|
|
|
|
|
|
|
| TC0900001453.mm.2 |
Smarcc1 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 |
9 |
110132023 |
NM_009211, BC052423 NM_009211, BC052423 |
20588 |
101 |
XY body DNA binding chromatin binding protein binding intracellular anatomical structure nucleus nucleus nucleoplasm cytoplasm DNA packaging chromatin organization nucleosome disassembly chromatin remodeling nervous system development insulin receptor signaling pathway animal organ morphogenesis SWI/SNF complex SWI/SNF complex SWI/SNF complex SWI/SNF complex negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of proteasomal ubiquitin-dependent protein catabolic process histone binding ATP-dependent chromatin remodeling positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II protein N-terminus binding SWI/SNF superfamily-type complex npBAF complex npBAF complex nBAF complex nBAF complex |
|
| TC0100002894.mm.2 |
Bcl2 |
B cell leukemia/lymphoma 2 |
1 |
-106538175, -106712164 |
NM_009741, NM_177410, BC068988, BC095964 NM_009741, NM_177410, BC068988, BC095964 NM_009741, NM_177410, BC068988, BC095964 NM_009741, NM_177410, BC068988, BC095964 |
12043 |
742 |
protein polyubiquitination cell morphogenesis response to acid chemical ossification ovarian follicle development metanephros development ureteric bud development branching involved in ureteric bud morphogenesis branching involved in ureteric bud morphogenesis behavioral fear response leukocyte homeostasis B cell homeostasis kidney development kidney development release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphocyte homeostasis lymphocyte homeostasis lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development response to ischemia renal system process protein binding intracellular anatomical structure nucleus nucleus nucleoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane cytosol cytosol protein dephosphorylation melanin metabolic process regulation of nitrogen utilization cellular calcium ion homeostasis apoptotic process apoptotic process cellular response to DNA damage stimulus response to oxidative stress actin filament organization axonogenesis cell aging transcription factor binding cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation male gonad development extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to oxidative stress apoptotic mitochondrial changes response to toxic substance response to toxic substance post-embryonic development post-embryonic development animal organ morphogenesis response to iron ion response to UV-B response to gamma radiation regulation of gene expression regulation of autophagy negative regulation of autophagy negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process negative regulation of cardiac muscle cell apoptotic process mesenchymal cell development positive regulation of neuron maturation positive regulation of smooth muscle cell migration channel activity membrane membrane integral component of membrane channel inhibitor activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation protein phosphatase binding cochlear nucleus development gland morphogenesis regulation of transmembrane transporter activity mitochondrial crista hemopoiesis B cell differentiation T cell differentiation T cell differentiation negative regulation of ossification positive regulation of cell growth negative regulation of cell growth melanocyte differentiation melanocyte differentiation negative regulation of cell migration positive regulation of B cell proliferation hair follicle morphogenesis axon regeneration ubiquitin protein ligase binding regulation of protein stability nuclear membrane nuclear membrane mitochondrial membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization protein-containing complex negative regulation of myeloid cell apoptotic process T cell differentiation in thymus positive regulation of peptidyl-serine phosphorylation negative regulation of osteoblast proliferation response to cytokine response to cytokine response to nicotine organ growth regulation of growth positive regulation of multicellular organism growth B cell proliferation cellular response to glucose starvation response to drug response to drug response to hydrogen peroxide identical protein binding protein homodimerization activity regulation of apoptotic process T cell homeostasis T cell homeostasis negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process regulation of programmed cell death positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment pigmentation negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process ear development ear development protein-containing complex binding regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability pore complex protein heterodimerization activity protein heterodimerization activity focal adhesion assembly developmental pigmentation developmental pigmentation regulation of developmental pigmentation positive regulation of developmental pigmentation positive regulation of developmental pigmentation perinuclear region of cytoplasm spleen development spleen development thymus development thymus development response to steroid hormone digestive tract morphogenesis developmental growth oocyte development positive regulation of skeletal muscle fiber development pigment granule organization homeostasis of number of cells within a tissue regulation of catalytic activity B cell receptor signaling pathway response to glucocorticoid response to glucocorticoid BH domain binding neuron apoptotic process neuron apoptotic process BH3 domain binding defense response to virus protein phosphatase 2A binding regulation of cell cycle regulation of mitochondrial membrane potential regulation of calcium ion transport intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress repressing transcription factor binding cellular response to organic substance cellular response to hypoxia reactive oxygen species metabolic process extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway in absence of ligand cell-cell adhesion negative regulation of G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle negative regulation of reactive oxygen species metabolic process negative regulation of anoikis negative regulation of apoptotic signaling pathway negative regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of intrinsic apoptotic signaling pathway negative regulation of intrinsic apoptotic signaling pathway |
04141 04210 04510 04722 05014 05145 05200 05210 05215 05222 |
| TC1000003119.mm.2 |
Lrp1 |
low density lipoprotein receptor-related protein 1 |
10 |
-127538157 |
NM_008512 |
16971 |
324 |
protease binding astrocyte activation involved in immune response cardiac septum development calcium ion binding protein binding nucleus cytoplasm endosome early endosome Golgi apparatus cytoskeleton plasma membrane integral component of plasma membrane clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis phagocytosis lysosomal transport positive regulation of cytosolic calcium ion concentration protein kinase C-activating G protein-coupled receptor signaling pathway multicellular organism development cholesterol metabolic process cell population proliferation external side of plasma membrane negative regulation of cell-substrate adhesion positive regulation of cholesterol efflux positive regulation of cell death positive regulation of neuron projection development negative regulation of neuron projection development negative regulation of smooth muscle cell migration coreceptor activity membrane integral component of membrane basolateral plasma membrane alpha-2 macroglobulin receptor activity cell junction clathrin-coated vesicle negative regulation of Wnt signaling pathway dendrite clathrin heavy chain binding positive regulation of protein binding positive regulation of lipid transport regulation of cholesterol transport regulation of phospholipase A2 activity insulin-responsive compartment regulation of actin cytoskeleton organization apolipoprotein binding positive regulation of insulin secretion involved in cellular response to glucose stimulus aorta morphogenesis cargo receptor activity cargo receptor activity neuronal cell body negative regulation of apoptotic process receptor complex apoptotic cell clearance negative regulation of neuron apoptotic process cellular lipid catabolic process axonal growth cone protein-containing complex binding apical part of cell synapse positive regulation of axon extension positive regulation of endocytosis metal ion binding perinuclear region of cytoplasm positive regulation of axon extension involved in regeneration positive regulation of collateral sprouting of injured axon positive regulation of phagocytosis positive regulation of protein transport negative regulation of cytosolic calcium ion concentration negative regulation of focal adhesion assembly negative regulation of cell death coronary vasculature development chemoattraction of axon positive regulation of ERK1 and ERK2 cascade amyloid-beta clearance amyloid-beta clearance by transcytosis amyloid-beta clearance by transcytosis amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process transport across blood-brain barrier positive regulation of Schwann cell migration positive regulation of amyloid-beta clearance positive regulation of protein localization to plasma membrane positive regulation of cholesterol import positive regulation of transcytosis cellular response to amyloid-beta positive regulation of vascular associated smooth muscle cell migration positive regulation of lysosomal protein catabolic process positive regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of platelet-derived growth factor receptor-beta signaling pathway |
05010 05144 |
| TC0500001692.mm.2 |
Eif3b |
eukaryotic translation initiation factor 3, subunit B |
5 |
140419304 |
NM_133916, BC023767, BC031704, BC051065 NM_133916, BC023767, BC031704, BC051065 NM_133916, BC023767, BC031704, BC051065 NM_133916, BC023767, BC031704, BC051065 |
27979 |
38 |
nucleic acid binding RNA binding translation initiation factor activity translation initiation factor activity translation initiation factor activity protein binding cytoplasm eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex translation translational initiation translational initiation translational initiation regulation of translational initiation translation initiation factor binding synapse synapse eukaryotic translation initiation factor 3 complex, eIF3m IRES-dependent viral translational initiation viral translational termination-reinitiation |
03013 |
| TC0100001858.mm.2 |
Nek2 |
NIMA (never in mitosis gene a)-related expressed kinase 2 |
1 |
191821472 |
NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576 NM_010892, BC010302, BC011316, BC057576 |
18005 |
48 |
mitotic sister chromatid segregation nucleotide binding chromosome, centromeric region kinetochore condensed nuclear chromosome spindle pole blastocyst development protein kinase activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm chromosome cytoplasm centrosome centrosome cytoskeleton microtubule protein phosphorylation protein phosphorylation cell cycle chromosome segregation chromosome segregation chromosome segregation kinase activity phosphorylation transferase activity protein phosphatase binding midbody positive regulation of telomere maintenance via telomerase protein-containing complex negative regulation of DNA binding regulation of mitotic centrosome separation protein autophosphorylation metal ion binding centrosome separation cell division meiotic cell cycle positive regulation of telomerase activity regulation of attachment of spindle microtubules to kinetochore mitotic spindle assembly negative regulation of centriole-centriole cohesion positive regulation of telomere capping |
|
| TC1300000259.mm.2 |
H2bc3 |
H2B clustered histone 3 |
13 |
23746733 |
NM_175664, BC116853, BC116857 NM_175664, BC116853, BC116857 NM_175664, BC116853, BC116857 |
319178 |
18 |
nucleosome DNA binding nucleus nucleoplasm nucleoplasm chromosome cytosol nucleosome assembly protein heterodimerization activity |
05322 |
| TC0600001474.mm.2 |
D6Wsu163e |
DNA segment, Chr 6, Wayne State University 163, expressed |
6 |
126939965 |
NM_138594, BC016429 NM_138594, BC016429 |
28040 |
17 |
molecular_function cytoplasm cytoplasm regulation of mast cell degranulation regulation of mast cell degranulation |
|
| TC1500002223.mm.2 |
Lima1 |
LIM domain and actin binding 1 |
15 |
-99778467, -99778467 |
NM_001113545, NM_023063, BC031490 NM_001113545, NM_023063, BC031490 NM_001113545, NM_023063, BC031490 |
65970 |
51 |
stress fiber ruffle actin binding actin monomer binding protein binding cytoplasm cytosol cytoskeleton plasma membrane plasma membrane brush border focal adhesion lipid metabolic process steroid metabolic process cholesterol metabolic process actin cytoskeleton actin cytoskeleton actin cytoskeleton membrane cell migration intestinal cholesterol absorption negative regulation of actin filament depolymerization brush border membrane ruffle organization ruffle organization cleavage furrow cholesterol homeostasis cell projection metal ion binding actin filament binding actin filament binding actin filament binding actin filament bundle assembly actin filament bundle assembly |
|
| TC1300000175.mm.2 |
H2bc14 |
H2B clustered histone 14 |
13 |
21722043 |
NM_178200, BC139381, BC139382 NM_178200, BC139381, BC139382 NM_178200, BC139381, BC139382 |
319186 |
13 |
nucleosome DNA binding nucleus nucleoplasm nucleoplasm chromosome cytosol nucleosome assembly protein heterodimerization activity |
05322 |
| TC0400003349.mm.2 |
Mmachc |
methylmalonic aciduria cblC type, with homocystinuria |
4 |
-116702433 |
NM_025962, BC054756 NM_025962, BC054756 |
67096 |
21 |
cytoplasm cytoplasm mitochondrion glutathione metabolic process cobalamin metabolic process cobalamin metabolic process oxidoreductase activity transferase activity cobalamin binding demethylase activity demethylase activity cyanocobalamin reductase (cyanide-eliminating) activity cyanocobalamin reductase (cyanide-eliminating) activity protein homodimerization activity glutathione binding demethylation FAD binding FAD binding |
04977 |
| TC1700000477.mm.2 |
Rpl10a |
ribosomal protein L10A |
17 |
28328564, 28328470 |
NM_011287, BC006039, BC083346 NM_011287, BC006039, BC083346 NM_011287, BC006039, BC083346 |
19896 |
33 |
maturation of LSU-rRNA cytoplasmic translation RNA binding structural constituent of ribosome mitochondrion ribosome translation postsynaptic density large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit polysomal ribosome synapse synapse |
03010 |
| TC0700004409.mm.2 |
Oat |
ornithine aminotransferase |
7 |
-132557474 |
NM_016978, BC008119 NM_016978, BC008119 |
18242 |
49 |
catalytic activity ornithine-oxo-acid transaminase activity nucleoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrial matrix transaminase activity arginine catabolic process to proline via ornithine transferase activity arginine catabolic process to glutamate pyridoxal phosphate binding identical protein binding identical protein binding |
00330 01100 |
| TC1300000167.mm.2 |
|
|
|
|
|
|
|
|
|
| TC0300002334.mm.2 |
Fdps |
farnesyl diphosphate synthetase |
3 |
-89093587 |
NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886 NM_001253751, NM_134469, BC048497, BC087886 |
110196 |
37 |
dimethylallyltranstransferase activity geranyltranstransferase activity geranyltranstransferase activity nucleoplasm cytoplasm mitochondrion mitochondrial matrix peroxisome cytosol lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process isoprenoid biosynthetic process sterol biosynthetic process transferase activity farnesyl diphosphate biosynthetic process farnesyl diphosphate biosynthetic process positive regulation of cholesterol biosynthetic process metal ion binding positive regulation of cell growth involved in cardiac muscle cell development |
00900 01100 |
| TC1900000170.mm.2 |
Eef1g |
eukaryotic translation elongation factor 1 gamma |
19 |
8967040 |
NM_026007, BC023495, BC083071, BC099413, BC117547, BC118522 NM_026007, BC023495, BC083071, BC099413, BC117547, BC118522 NM_026007, BC023495, BC083071, BC099413, BC117547, BC118522 NM_026007, BC023495, BC083071, BC099413, BC117547, BC118522 NM_026007, BC023495, BC083071, BC099413, BC117547, BC118522 NM_026007, BC023495, BC083071, BC099413, BC117547, BC118522 |
67160 |
32 |
translation elongation factor activity nucleus cytoplasm cytoplasm endoplasmic reticulum translation translational elongation |
|
| TC0100003649.mm.2 |
Smyd3 |
SET and MYND domain containing 3 |
1 |
-178951959 |
NM_027188, BC052431, BC061485 NM_027188, BC052431, BC061485 NM_027188, BC052431, BC061485 |
69726 |
29 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II complex binding RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytosol chromatin organization nucleosome assembly negative regulation of protein kinase activity methyltransferase activity myotube cell development transferase activity histone-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity histone-lysine N-methyltransferase activity methylation positive regulation of peptidyl-serine phosphorylation histone lysine methylation establishment of protein localization positive regulation of transcription by RNA polymerase II metal ion binding cellular response to dexamethasone stimulus |
|
| TC1600001320.mm.2 |
Cdc45 |
cell division cycle 45 |
16 |
-18780446 |
NM_001161623, NM_009862, BC028635 NM_001161623, NM_009862, BC028635 NM_001161623, NM_009862, BC028635 |
12544 |
41 |
double-strand break repair via break-induced replication chromatin binding DNA replication origin binding single-stranded DNA binding nucleus nucleoplasm centrosome DNA replication DNA replication initiation cell cycle DNA replication preinitiation complex regulation of chromatin silencing at telomere ciliary basal body mitotic DNA replication preinitiation complex assembly |
04110 |
| TC0100003612.mm.2 |
Chml |
choroideremia-like |
1 |
-175682237 |
NM_021350, BC118932 NM_021350, BC118932 |
12663 |
17 |
GDP-dissociation inhibitor activity GTPase activator activity nucleus nucleoplasm cytoplasm cytosol cytosol Rab-protein geranylgeranyltransferase complex Rab-protein geranylgeranyltransferase complex intracellular protein transport small GTPase mediated signal transduction vesicle-mediated transport protein geranylgeranylation protein geranylgeranylation small GTPase binding |
|
| TC0400002110.mm.2 |
Noc2l |
NOC2 like nucleolar associated transcriptional repressor |
4 |
156236014, 156236009 |
NM_021303, BC020013 NM_021303, BC020013 |
57741 |
25 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II p53 binding negative regulation of B cell apoptotic process chromatin binding transcription corepressor activity transcription corepressor activity nucleus nucleus nucleoplasm nucleoplasm chromosome nucleolus nucleolus cytosol apoptotic process Noc1p-Noc2p complex Noc2p-Noc3p complex nucleosome binding nucleosomal histone binding chromatin assembly cellular response to UV negative regulation of histone acetylation negative regulation of histone acetylation negative regulation of histone acetylation ribosomal large subunit biogenesis histone binding histone binding histone binding repressing transcription factor binding repressing transcription factor binding negative regulation of intrinsic apoptotic signaling pathway |
|
| TC0200001972.mm.2 |
|
|
|
|
NM_024193, NR_028528, BC021355 NM_024193, NR_028528, BC021355 NM_024193, NR_028528, BC021355 |
|
|
fibrillar center molecular_function RNA binding cellular_component nucleus sno(s)RNA-containing ribonucleoprotein complex cytoplasm biological_process snoRNA binding snoRNA binding box C/D RNP complex small-subunit processome ribosome biogenesis pre-snoRNP complex histone methyltransferase binding |
|
| TC0100003027.mm.2 |
Dars |
aspartyl-tRNA synthetase |
1 |
-128412117, -128363706 |
NM_145507, NM_177445, BC008638 NM_145507, NM_177445, BC008638 NM_145507, NM_177445, BC008638 |
226414 |
31 |
nucleotide binding nucleic acid binding RNA binding aminoacyl-tRNA ligase activity aspartate-tRNA ligase activity aspartate-tRNA ligase activity ATP binding cytoplasm cytosol cytosol translation tRNA aminoacylation for protein translation aspartyl-tRNA aminoacylation aspartyl-tRNA aminoacylation ligase activity aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex synapse |
00970 |
| TC0700004293.mm.2 |
Coro1a |
coronin, actin binding protein 1A |
7 |
-126699773, -126699773 |
NM_009898, BC002136, BC053398 NM_009898, BC002136, BC053398 NM_009898, BC002136, BC053398 |
12721 |
88 |
immunological synapse immunological synapse phagolysosome assembly phagocytic cup actin binding actin monomer binding protein binding cytoplasm early endosome cytoskeleton actin filament plasma membrane plasma membrane cell-cell junction calcium ion transport phagocytosis actin filament organization actin filament organization protein C-terminus binding regulation of actin polymerization or depolymerization cytoskeletal protein binding regulation of cell shape actin cytoskeleton membrane cell migration cell migration lamellipodium actin cytoskeleton organization positive regulation of cell migration axon leukocyte chemotaxis regulation of actin filament polymerization cortical actin cytoskeleton cell leading edge negative regulation of vesicle fusion cytoplasmic vesicle cell-substrate adhesion myosin heavy chain binding stereocilium tip uropod organization regulation of actin cytoskeleton organization protein-containing complex response to cytokine nerve growth factor signaling pathway positive regulation of T cell proliferation identical protein binding protein homodimerization activity T cell homeostasis natural killer cell degranulation negative regulation of neuron apoptotic process phosphatidylinositol 3-kinase binding synapse phagocytic vesicle homeostasis of number of cells within a tissue positive regulation of T cell activation positive chemotaxis actin filament binding actin filament binding actin filament binding negative regulation of actin nucleation regulation of release of sequestered calcium ion into cytosol early endosome to recycling endosome transport cellular response to interleukin-4 glutamatergic synapse |
04145 |
| TC0900001005.mm.2 |
Fam214a |
family with sequence similarity 214, member A |
9 |
74952879, 74976110, 74953052 |
NM_001113283, NM_153584, BC031353 NM_001113283, NM_153584, BC031353 NM_001113283, NM_153584, BC031353 |
235493 |
15 |
molecular_function cellular_component biological_process |
|
| TC0100002739.mm.2 |
Ncl |
nucleolin |
1 |
-86344718 |
NM_010880, BC005460 NM_010880, BC005460 |
17975 |
127 |
angiogenesis fibrillar center dense fibrillar component nucleic acid binding DNA binding single-stranded DNA binding RNA binding RNA binding signaling receptor binding calcium ion binding protein binding nucleus nucleus nucleoplasm nucleoplasm spliceosomal complex chromosome nucleolus nucleolus cytoplasm cell cortex endocytosis protein C-terminus binding cell surface negative regulation of translation positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production selenocysteine insertion sequence binding cytoplasmic ribonucleoprotein granule rRNA primary transcript binding telomeric DNA binding histone binding identical protein binding negative regulation of apoptotic process laminin binding sequence-specific DNA binding DNA topoisomerase binding positive regulation of transcription by RNA polymerase II positive regulation of mRNA splicing, via spliceosome mRNA 5'-UTR binding cellular response to lipopolysaccharide cellular response to epidermal growth factor stimulus positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ErbB-4 class receptor binding cellular response to leukemia inhibitory factor ribonucleoprotein complex regulation of rRNA processing |
|
| TC1600000788.mm.2 |
Pros1 |
protein S (alpha) |
16 |
62854306 |
NM_011173, BC128316 NM_011173, BC128316 |
19128 |
48 |
calcium ion binding extracellular region extracellular space extracellular space extracellular space blood coagulation hemostasis negative regulation of blood coagulation protein-containing complex fibrinolysis protein-containing complex binding positive regulation of phagocytosis negative regulation of coagulation |
04610 |
| TC1300000192.mm.2 |
H2bc11 |
H2B clustered histone 11 |
13 |
22043197 |
NM_178198 |
319183 |
5 |
nucleus nucleoplasm cytosol |
05322 |
| TC0700002828.mm.2 |
Gpi1 |
glucose-6-phosphate isomerase 1 |
7 |
-34201326 |
NM_008155, BC086640, BC088995, BC157972, BC172124 NM_008155, BC086640, BC088995, BC157972, BC172124 NM_008155, BC086640, BC088995, BC157972, BC172124 NM_008155, BC086640, BC088995, BC157972, BC172124 NM_008155, BC086640, BC088995, BC157972, BC172124 |
14751 |
230 |
in utero embryonic development mesoderm formation positive regulation of immunoglobulin production glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity cytokine activity protein binding extracellular region extracellular space nucleoplasm cytoplasm cytosol cytosol plasma membrane plasma membrane carbohydrate metabolic process gluconeogenesis glycolytic process glycolytic process glycolytic process growth factor activity positive regulation of endothelial cell migration isomerase activity ubiquitin protein ligase binding erythrocyte homeostasis glucose homeostasis neuron projection negative regulation of cysteine-type endopeptidase activity involved in apoptotic process myelin sheath response to morphine negative regulation of neuron apoptotic process monosaccharide binding monosaccharide binding glucose 6-phosphate metabolic process glucose 6-phosphate metabolic process ciliary membrane glycolytic process through glucose-6-phosphate canonical glycolysis |
00010 00030 00500 00520 01100 |
| TC1300001374.mm.2 |
Net1 |
neuroepithelial cell transforming gene 1 |
13 |
-3882017, -3882017 |
NM_001047159, NM_019671, BC004699 NM_001047159, NM_019671, BC004699 NM_001047159, NM_019671, BC004699 |
56349 |
33 |
guanyl-nucleotide exchange factor activity protein binding nucleus cytoplasm plasma membrane small GTPase binding regulation of Rho protein signal transduction positive regulation of Rho protein signal transduction intracellular signal transduction positive regulation of apoptotic process positive regulation of GTPase activity myoblast migration cellular response to hydrogen peroxide cellular response to ionizing radiation positive regulation of substrate adhesion-dependent cell spreading |
|
| TC1000002488.mm.2 |
Polr2e |
polymerase (RNA) II (DNA directed) polypeptide E |
10 |
-80035952 |
NM_025554, BC026842, BC045521 NM_025554, BC026842, BC045521 NM_025554, BC026842, BC045521 |
66420 |
24 |
DNA binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm nucleoplasm RNA polymerase II, core complex RNA polymerase II, core complex RNA polymerase III complex RNA polymerase I complex transcription, DNA-templated transcription by RNA polymerase II transcription by RNA polymerase II |
00230 00240 01100 03020 05016 |
| TC0800003076.mm.2 |
Aprt |
adenine phosphoribosyl transferase |
8 |
-122574636 |
NM_009698, BC005667 NM_009698, BC005667 |
11821 |
95 |
adenine binding adenine binding adenine phosphoribosyltransferase activity adenine phosphoribosyltransferase activity adenine phosphoribosyltransferase activity adenine phosphoribosyltransferase activity nucleoplasm cytoplasm cytosol purine ribonucleoside salvage purine ribonucleoside salvage adenine salvage adenine salvage lactation grooming behavior nucleoside metabolic process AMP binding AMP binding transferase activity transferase activity, transferring glycosyl groups AMP salvage adenine metabolic process adenine metabolic process adenine metabolic process |
00230 01100 |
| TC0300001255.mm.2 |
Sec24d |
Sec24 related gene family, member D (S. cerevisiae) |
3 |
123267495 |
NM_027135, BC049257, BC067020 NM_027135, BC049257, BC067020 NM_027135, BC049257, BC067020 |
69608 |
23 |
SNARE binding SNARE binding in utero embryonic development endoplasmic reticulum to Golgi vesicle-mediated transport zinc ion binding zinc ion binding COPII vesicle coat COPII vesicle coat intracellular membrane-bounded organelle endoplasmic reticulum exit site COPII-coated vesicle cargo loading COPII-coated vesicle cargo loading |
04141 |
| TC0700000870.mm.2 |
Nomo1 |
nodal modulator 1 |
7 |
46033695 |
NM_153057, BC033923, BC072630 NM_153057, BC033923, BC072630 NM_153057, BC033923, BC072630 |
211548 |
28 |
molecular_function endoplasmic reticulum membrane endoplasmic reticulum membrane biological_process membrane integral component of membrane carbohydrate binding protein-containing complex |
|
| MG-1-pos-10340458_st |
|
|
|
|
|
|
|
|
|
| TC0800002523.mm.2 |
Abce1 |
ATP-binding cassette, sub-family E (OABP), member 1 |
8 |
-79683441 |
NM_015751, BC005422 NM_015751, BC005422 |
24015 |
31 |
ribosomal subunit export from nucleus nucleotide binding iron ion binding ATP binding cytoplasm mitochondrion cytosol eukaryotic translation initiation factor 3 complex translational initiation translational termination ATPase activity ribosomal small subunit binding endoribonuclease inhibitor activity negative regulation of endoribonuclease activity |
|
| TC0300002203.mm.2 |
Tmem144 |
transmembrane protein 144 |
3 |
-79812563, -79812563, -79812563, -79812563 |
NM_027495, BC018493 NM_027495, BC018493 |
70652 |
11 |
molecular_function cellular_component biological_process carbohydrate transmembrane transporter activity membrane integral component of membrane carbohydrate transmembrane transport |
|
| TC0400002010.mm.2 |
Nol9 |
nucleolar protein 9 |
4 |
152039320, 152039320, 152039337 |
NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099 NM_001159599, NM_028727, BC125432, BC132099 |
74035 |
19 |
nucleotide binding cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA RNA binding ATP binding nucleus nucleolus rRNA processing RNA processing kinase activity transferase activity intermediate filament cytoskeleton polynucleotide 5'-hydroxyl-kinase activity polynucleotide 5'-hydroxyl-kinase activity |
|
| TC0600000388.mm.2 |
Tbxas1 |
thromboxane A synthase 1, platelet |
6 |
38918985 |
NM_011539, BC029014 NM_011539, BC029014 |
21391 |
29 |
prostaglandin biosynthetic process monooxygenase activity thromboxane-A synthase activity thromboxane-A synthase activity thromboxane-A synthase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process icosanoid metabolic process prostaglandin metabolic process membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen lyase activity isomerase activity heme binding cellular chloride ion homeostasis positive regulation of vasoconstriction metal ion binding hydroperoxy icosatetraenoate dehydratase activity |
00590 01100 |
| TC0400002460.mm.2 |
Ubap2 |
ubiquitin-associated protein 2 |
4 |
-41194314 |
NM_026872, BC007179 NM_026872, BC007179 |
68926 |
25 |
nucleus cytoplasm |
|
| TC1300001751.mm.2 |
Gmds |
GDP-mannose 4, 6-dehydratase |
13 |
-31819585 |
NM_146041, BC031788, BC093502 NM_146041, BC031788, BC093502 NM_146041, BC031788, BC093502 |
218138 |
21 |
cytoplasm GDP-mannose 4,6-dehydratase activity lyase activity GDP-mannose metabolic process 'de novo' GDP-L-fucose biosynthetic process |
00051 00520 01100 |
| TC1100001634.mm.2 |
Atp6v0a1 |
ATPase, H+ transporting, lysosomal V0 subunit A1 |
11 |
101010397, 101009440, 101009440, 101009440 |
NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 NM_001243049, NM_001243050, NM_001243051, NM_016920, BC066839, BC071182 |
11975 |
48 |
vacuolar proton-transporting V-type ATPase, V0 domain protein binding cytoplasm Golgi apparatus cytosol plasma membrane plasma membrane ion transport vacuolar acidification synaptic vesicle proton transmembrane transporter activity membrane integral component of membrane regulation of macroautophagy vacuolar proton-transporting V-type ATPase complex nuclear speck integral component of synaptic vesicle membrane cytoplasmic vesicle proton-transporting V-type ATPase, V0 domain intracellular organelle intracellular membrane-bounded organelle proton-transporting ATPase activity, rotational mechanism perinuclear region of cytoplasm ATPase binding ATPase binding toxin transport proton transmembrane transport |
00190 01100 04142 04145 04966 05323 |
| TC0200001843.mm.2 |
Sord |
sorbitol dehydrogenase |
2 |
122234838 |
NM_146126, BC024124, BC030875, BC092291 NM_146126, BC024124, BC030875, BC092291 NM_146126, BC024124, BC030875, BC092291 NM_146126, BC024124, BC030875, BC092291 |
20322 |
41 |
L-iditol 2-dehydrogenase activity L-iditol 2-dehydrogenase activity L-iditol 2-dehydrogenase activity mitochondrion cilium sorbitol metabolic process sorbitol catabolic process sorbitol catabolic process zinc ion binding response to hormone membrane oxidoreductase activity flagellated sperm motility motile cilium identical protein binding cell projection fructose biosynthetic process D-xylulose reductase activity response to cadmium ion response to copper ion metal ion binding L-xylitol catabolic process L-xylitol metabolic process NAD binding extracellular exosome |
00051 01100 |
| TC0900000504.mm.2 |
Dpagt1 |
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) |
9 |
44326814 |
NM_007875, BC003943, BC010474 NM_007875, BC003943, BC010474 NM_007875, BC003943, BC010474 |
13478 |
29 |
UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity endoplasmic reticulum endoplasmic reticulum membrane UDP-N-acetylglucosamine metabolic process protein N-linked glycosylation dolichol-linked oligosaccharide biosynthetic process dolichol-linked oligosaccharide biosynthetic process dolichyl diphosphate biosynthetic process phospho-N-acetylmuramoyl-pentapeptide-transferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups dolichol metabolic process intracellular membrane-bounded organelle metal ion binding |
00510 01100 |
| TC1900000664.mm.2 |
Sfxn3 |
sideroflexin 3 |
19 |
45047575 |
NM_001178012, NM_001178013, NM_053197, BC012208 NM_001178012, NM_001178013, NM_053197, BC012208 NM_001178012, NM_001178013, NM_053197, BC012208 NM_001178012, NM_001178013, NM_053197, BC012208 |
94280 |
34 |
mitochondrion mitochondrion mitochondrion one-carbon metabolic process ion transport amino acid transport ion transmembrane transporter activity membrane integral component of membrane transmembrane transporter activity serine transmembrane transporter activity serine transmembrane transporter activity integral component of mitochondrial inner membrane mitochondrial membrane transmembrane transport serine import into mitochondrion serine import into mitochondrion mitochondrial transmembrane transport mitochondrial transmembrane transport |
|
| TC1200001598.mm.2 |
Dus4l |
dihydrouridine synthase 4-like (S. cerevisiae) |
12 |
-31640054 |
NM_028002, BC109351 NM_028002, BC109351 |
71916 |
15 |
catalytic activity tRNA processing oxidoreductase activity tRNA dihydrouridine synthase activity flavin adenine dinucleotide binding |
|
| TC1500001155.mm.2 |
Ptger4 |
prostaglandin E receptor 4 (subtype EP4) |
15 |
-5233398 |
NM_001136079, NM_008965, BC009023, BC011193 NM_001136079, NM_008965, BC009023, BC011193 NM_001136079, NM_008965, BC009023, BC011193 NM_001136079, NM_008965, BC009023, BC011193 |
19219 |
209 |
negative regulation of cytokine production positive regulation of cytokine production positive regulation of protein phosphorylation negative regulation of peptide secretion G protein-coupled receptor activity prostaglandin receptor activity prostaglandin E receptor activity prostaglandin E receptor activity prostaglandin E receptor activity plasma membrane plasma membrane inflammatory response signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration JNK cascade positive regulation of cell population proliferation positive regulation of gene expression negative regulation of hydrogen peroxide metabolic process regulation of circadian sleep/wake cycle, wakefulness positive regulation of smooth muscle cell migration membrane integral component of membrane regulation of ossification nuclear membrane response to lipopolysaccharide negative regulation of interleukin-1 alpha production negative regulation of tumor necrosis factor production positive regulation of interleukin-10 production positive regulation of interleukin-8 production negative regulation of integrin activation positive regulation of urine volume positive regulation of renal sodium excretion T-helper cell differentiation negative regulation of circadian sleep/wake cycle, REM sleep chemokinesis positive regulation of tyrosine phosphorylation of STAT protein neuronal cell body positive regulation of cAMP-mediated signaling neuron projection terminus positive regulation of osteoblast differentiation positive regulation of ossification positive regulation of bone resorption positive regulation of cell adhesion positive regulation of circadian sleep/wake cycle, non-REM sleep positive regulation of protein secretion negative regulation of inflammatory response negative regulation of inflammatory response negative regulation of inflammatory response negative regulation of inflammatory response positive regulation of inflammatory response regulation of stress fiber assembly negative regulation of nitric-oxide synthase biosynthetic process bone development positive regulation of mucus secretion ERK1 and ERK2 cascade cellular response to mechanical stimulus cellular response to prostaglandin E stimulus positive regulation of wound healing ductus arteriosus closure positive regulation of hyaluronan biosynthetic process negative regulation of ductus arteriosus closure negative regulation of small intestine smooth muscle contraction positive regulation of calcitonin secretion positive regulation of chemokinesis positive regulation of substance P secretion positive regulation of matrix metallopeptidase secretion negative regulation of endothelin production positive regulation of substance P secretion, neurotransmission positive regulation of ovarian follicle development positive regulation of antral ovarian follicle growth positive regulation of neutrophil extravasation negative regulation of eosinophil extravasation |
04080 |
| TC1300002036.mm.2 |
Nop16 |
NOP16 nucleolar protein |
13 |
-54584190 |
NM_178605, BC012213 NM_178605, BC012213 |
28126 |
21 |
nucleus nucleoplasm nucleolus nucleolus ribosomal large subunit biogenesis intracellular membrane-bounded organelle |
|
| TC1700000657.mm.2 |
Lsm2 |
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated |
17 |
34982129, 34981853, 34982129, 34981853 |
NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 NM_001110101, NM_001204273, NM_001204274, NM_030597, BC014288, BC049543 |
27756 |
32 |
spliceosomal tri-snRNP complex assembly mRNA splicing, via spliceosome mRNA splicing, via spliceosome P-body RNA binding protein binding nucleus nucleoplasm spliceosomal complex U6 snRNP cytoplasm mRNA processing mRNA catabolic process RNA splicing protein kinase binding small GTPase binding U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome Lsm2-8 complex Lsm1-7-Pat1 complex |
03018 03040 |
| TC1500000002.mm.2 |
Selenop |
selenoprotein P |
15 |
3270766, 3270976, 3270810 |
NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991 NM_001042613, NM_001042614, NM_009155, BC001991 |
20363 |
74 |
selenium compound metabolic process selenium compound metabolic process selenium compound metabolic process protein binding extracellular region extracellular region extracellular space brain development locomotory behavior selenium binding selenium binding post-embryonic development sexual reproduction regulation of growth |
|
| TC0800002503.mm.2 |
Tmem184c |
transmembrane protein 184C |
8 |
-77595979, -77595977 |
NM_145599, BC004056 NM_145599, BC004056 |
234463 |
16 |
transporter activity transport membrane integral component of membrane |
|
| TC0200004725.mm.2 |
Tasp1 |
taspase, threonine aspartase 1 |
2 |
-139833478, -139976218 |
NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 NM_001159640, NM_001159641, NM_001289611, NM_175225, NR_110350, NR_110351, NR_110352, BC024597 |
75812 |
25 |
threonine-type endopeptidase activity threonine-type endopeptidase activity cytoplasm proteolysis peptidase activity hydrolase activity identical protein binding positive regulation of transcription, DNA-templated protein maturation |
|
| TC1000000752.mm.2 |
Slc19a1 |
solute carrier family 19 (folate transporter), member 1 |
10 |
77033211, 77032738 |
NM_001199271, NM_031196, BC015263 NM_001199271, NM_031196, BC015263 NM_001199271, NM_031196, BC015263 |
20509 |
60 |
folic acid binding folic acid binding plasma membrane plasma membrane integral component of plasma membrane organic anion transmembrane transporter activity folic acid transmembrane transporter activity folic acid transmembrane transporter activity folate:anion antiporter activity folate:anion antiporter activity antiporter activity methotrexate transmembrane transporter activity methotrexate transmembrane transporter activity organic anion transport folic acid transport membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane brush border membrane vitamin transport methotrexate transport methotrexate transport transmembrane transport cyclic-GMP-AMP binding vitamin transmembrane transporter activity folate transmembrane transport folate transmembrane transport folate transmembrane transport folate import across plasma membrane folate import across plasma membrane |
04977 |
| TC1100004296.mm.2 |
Nme1 |
NME/NM23 nucleoside diphosphate kinase 1 |
11 |
-93958924, -93958924 |
NM_008704, BC005629, NME/NM23 NM_008704, BC005629, NME/NM23 NM_008704, BC005629, NME/NM23 |
18102 |
75 |
nucleotide binding magnesium ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding negative regulation of myeloid leukocyte differentiation single-stranded DNA binding deoxyribonuclease activity nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity ATP binding GTP binding nucleus cytoplasm mitochondrion mitochondrial outer membrane centrosome cytosol intermediate filament nucleoside diphosphate phosphorylation GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process endocytosis nervous system development lactation nucleotide metabolic process negative regulation of gene expression positive regulation of neuron projection development membrane kinase activity phosphorylation transferase activity intermediate filament binding enzyme binding protein kinase binding cell differentiation mammary gland development ruffle membrane identical protein binding gamma-tubulin binding ribosomal small subunit binding myelin sheath positive regulation of DNA binding metal ion binding perinuclear region of cytoplasm positive regulation of epithelial cell proliferation |
00230 00240 01100 |
| TC0X00001784.mm.2 |
Pqbp1 |
polyglutamine binding protein 1 |
X |
-7894518, -7894518 |
NM_001252528, NM_001252529, NM_019478, BC009657, BC051673, BC157976 NM_001252528, NM_001252529, NM_019478, BC009657, BC051673, BC157976 NM_001252528, NM_001252529, NM_019478, BC009657, BC051673, BC157976 NM_001252528, NM_001252529, NM_019478, BC009657, BC051673, BC157976 NM_001252528, NM_001252529, NM_019478, BC009657, BC051673, BC157976 NM_001252528, NM_001252529, NM_019478, BC009657, BC051673, BC157976 |
54633 |
33 |
alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome activation of innate immune response positive regulation of defense response to virus by host immune system process double-stranded DNA binding nucleus nucleus cytoplasm cytoplasm centrosome cilium mRNA processing protein C-terminus binding RNA splicing cytoplasmic stress granule nuclear body nuclear speck nuclear speck neuron projection development positive regulation of type I interferon production stress granule assembly ribonucleoprotein complex binding ribonucleoprotein complex binding regulation of RNA splicing regulation of RNA splicing innate immune response regulation of dendrite morphogenesis defense response to virus cellular response to exogenous dsRNA neuronal ribonucleoprotein granule ciliary base positive regulation of non-motile cilium assembly |
03040 |
| TC0700002989.mm.2 |
Fcgrt |
Fc fragment of IgG receptor and transporter |
7 |
-45092992 |
NM_010189, BC003786 NM_010189, BC003786 |
14132 |
108 |
extracellular space endosome plasma membrane immune response external side of plasma membrane membrane integral component of membrane IgG binding beta-2-microglobulin binding beta-2-microglobulin binding |
|
| TC0200000636.mm.2 |
Gsn |
gelsolin |
2 |
35256358, 35266743, 35282379 |
NM_001206367, NM_001206368, NM_001206369, NM_146120, BC023143, BC060377 NM_001206367, NM_001206368, NM_001206369, NM_146120, BC023143, BC060377 NM_001206367, NM_001206368, NM_001206369, NM_146120, BC023143, BC060377 NM_001206367, NM_001206368, NM_001206369, NM_146120, BC023143, BC060377 NM_001206367, NM_001206368, NM_001206369, NM_146120, BC023143, BC060377 NM_001206367, NM_001206368, NM_001206369, NM_146120, BC023143, BC060377 |
227753 |
128 |
ruffle podosome actin binding calcium ion binding protein binding phosphatidylinositol-4,5-bisphosphate binding extracellular region extracellular space extracellular space extracellular space nucleus cytoplasm cytoplasm cytosol cytoskeleton plasma membrane focal adhesion phagocytosis, engulfment apoptotic process central nervous system development actin polymerization or depolymerization actin polymerization or depolymerization positive regulation of gene expression striated muscle atrophy actin cytoskeleton actin cytoskeleton vesicle-mediated transport sarcoplasm lamellipodium cell projection organization cell projection assembly actin cytoskeleton organization actin filament polymerization actin filament polymerization actin filament depolymerization actin filament depolymerization regulation of cell adhesion actin cap cortical actin cytoskeleton protein destabilization protein-containing complex response to muscle stretch phosphatidylinositol 3-kinase catalytic subunit binding phosphatidylinositol 3-kinase catalytic subunit binding sequestering of actin monomers myelin sheath actin nucleation myosin II binding phagocytic vesicle negative regulation of viral entry into host cell metal ion binding phosphatidylinositol-mediated signaling perinuclear region of cytoplasm actin filament severing actin filament severing actin filament severing actin filament binding barbed-end actin filament capping positive regulation of actin nucleation actin filament capping actin filament capping relaxation of cardiac muscle cilium assembly cellular response to cadmium ion cellular response to interferon-gamma regulation of podosome assembly cardiac muscle cell contraction actin filament reorganization renal protein absorption hepatocyte apoptotic process positive regulation of keratinocyte apoptotic process regulation of establishment of T cell polarity regulation of plasma membrane raft polarization regulation of receptor clustering positive regulation of protein processing in phagocytic vesicle amyloid fibril formation positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
04666 04810 |
| MG-1-pos-10339064_st |
|
|
|
|
|
|
|
|
|
| TC1800001138.mm.2 |
Stard4 |
StAR-related lipid transfer (START) domain containing 4 |
18 |
-33199137 |
NM_133774, BC005642 NM_133774, BC005642 |
170459 |
24 |
cytoplasm mitochondrion endoplasmic reticulum endoplasmic reticulum cytosol cytosol lipid transport lipid binding positive regulation of cholesterol esterification cholesterol transport involved in cholesterol storage cholesterol transport involved in cholesterol storage cholesterol binding cholesterol binding cholesterol binding cytoplasmic vesicle intracellular cholesterol transport intracellular cholesterol transport cholesterol esterification cholesterol import cholesterol import positive regulation of bile acid biosynthetic process cholesterol transfer activity cholesterol transfer activity |
|
| TC1000002043.mm.2 |
|
|
|
|
NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 NM_007444, NM_009665, BC011110, BC071220, BC080791, BC092072, BC138696, BC138697 |
|
|
in utero embryonic development adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity adenosylmethionine decarboxylase activity protein binding cytosol cytosol polyamine biosynthetic process spermine biosynthetic process spermine biosynthetic process spermidine biosynthetic process spermidine biosynthetic process lyase activity carboxy-lyase activity putrescine binding putrescine binding identical protein binding |
|
| TC1900001510.mm.2 |
Arhgap19 |
Rho GTPase activating protein 19 |
19 |
-41766587 |
NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195 NM_001163495, NM_027667, BC086680, BC139195 |
71085 |
22 |
GTPase activator activity cytoplasm plasma membrane signal transduction intracellular membrane-bounded organelle regulation of small GTPase mediated signal transduction |
|
| TC1900001691.mm.2 |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
19 |
-55067635, -55067635 |
NM_008149, BC019201 NM_008149, BC019201 |
14732 |
58 |
regulation of cytokine production glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane plasma membrane glycerol-3-phosphate metabolic process lipid metabolic process fatty acid metabolic process fatty acid metabolic process acyl-CoA metabolic process triglyceride metabolic process glycerophospholipid metabolic process diacylglycerol biosynthetic process phosphatidic acid biosynthetic process phosphatidylglycerol biosynthetic process O-acyltransferase activity phospholipid biosynthetic process response to glucose positive regulation of triglyceride biosynthetic process response to activity membrane integral component of membrane transferase activity transferase activity, transferring acyl groups triglyceride biosynthetic process triglyceride biosynthetic process mitochondrial membrane mitochondrial membrane interleukin-2 production cellular response to insulin stimulus positive regulation of multicellular organism growth positive regulation of activated T cell proliferation cellular lipid metabolic process defense response to virus fatty acid homeostasis phospholipid homeostasis negative regulation of activation-induced cell death of T cells |
00561 00564 01100 |
| TC1400000742.mm.2 |
Abhd4 |
abhydrolase domain containing 4 |
14 |
54259282, 54254128 |
NM_001205181, NM_134076, BC017532 NM_001205181, NM_134076, BC017532 NM_001205181, NM_134076, BC017532 |
105501 |
26 |
lysophospholipase activity lysophospholipase activity mitochondrion lipid droplet lipid metabolic process phosphatidic acid biosynthetic process lipid catabolic process hydrolase activity lysophosphatidic acid acyltransferase activity carboxylic ester hydrolase activity lipid homeostasis N-acylethanolamine metabolic process N-acylphosphatidylethanolamine metabolic process |
|
| TC0800000621.mm.2 |
Hpgd |
hydroxyprostaglandin dehydrogenase 15 (NAD) |
8 |
56294551 |
NM_008278, BC021157 NM_008278, BC021157 |
15446 |
43 |
prostaglandin E receptor activity extracellular space nucleoplasm cytoplasm cytoplasm cytosol lipid metabolic process fatty acid metabolic process prostaglandin metabolic process prostaglandin metabolic process transforming growth factor beta receptor signaling pathway female pregnancy female pregnancy parturition basolateral plasma membrane 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 15-hydroxyprostaglandin dehydrogenase (NAD+) activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor identical protein binding positive regulation of apoptotic process response to ethanol negative regulation of cell cycle NAD binding NAD+ binding ductus arteriosus closure positive regulation of vascular associated smooth muscle cell proliferation regulation of prostaglandin catabolic process |
|
| TC1200000132.mm.2 |
E2f6 |
E2F transcription factor 6 |
12 |
16810964 |
NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F NM_033270, NR_027677, BC019166, BC037656, BC057929, E2F |
50496 |
48 |
regulation of transcription involved in G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleoplasm DNA replication factor A complex transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell cycle protein dimerization activity MLL1 complex RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex |
|
| TC0700000904.mm.2 |
Prmt3 |
protein arginine N-methyltransferase 3 |
7 |
49778357 |
NM_133740, BC050775 NM_133740, BC050775 |
71974 |
35 |
protein binding cytoplasm cytosol protein methylation methyltransferase activity protein-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity transferase activity peptidyl-arginine methylation peptidyl-arginine methylation, to asymmetrical-dimethyl arginine negative regulation of protein ubiquitination methylation protein-arginine omega-N asymmetric methyltransferase activity ribosome binding metal ion binding dendritic spine morphogenesis modified amino acid binding |
|
| TC0800001906.mm.2 |
|
|
|
|
NM_177089, NM_199323, NR_106187, BC153048 NM_177089, NM_199323, NR_106187, BC153048 NM_177089, NM_199323, NR_106187, BC153048 NM_177089, NM_199323, NR_106187, BC153048 |
|
|
microtubule cytoskeleton organization microtubule cytoskeleton organization nucleus cytoplasm cytosol cytoskeleton cell cycle mitotic spindle organization cell population proliferation cell population proliferation nuclear receptor binding protein domain specific binding cerebral cortex development cerebral cortex development neurogenesis interkinetic nuclear migration estrogen receptor binding nuclear receptor coactivator activity regulation of microtubule-based process glucocorticoid receptor binding retinoic acid receptor binding retinoic acid receptor binding peroxisome proliferator activated receptor binding peroxisome proliferator activated receptor binding retinoid X receptor binding retinoid X receptor binding thyroid hormone receptor binding thyroid hormone receptor binding cell division |
|
| TC0200004410.mm.2 |
Gpr176 |
G protein-coupled receptor 176 |
2 |
-118277097 |
NM_201367, BC052037 NM_201367, BC052037 |
381413 |
18 |
G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway membrane integral component of membrane rhythmic process circadian behavior |
|
| TC1600000166.mm.2 |
Rrn3 |
RRN3 RNA polymerase I transcription factor homolog (yeast) |
16 |
13780698 |
NM_001039521, BC138774, BC138776 NM_001039521, BC138774, BC138776 NM_001039521, BC138774, BC138776 |
106298 |
36 |
RNA polymerase I core binding RNA polymerase I core promoter sequence-specific DNA binding RNA polymerase I general transcription initiation factor activity in utero embryonic development nucleus nucleolus DNA-templated transcription, initiation transcription initiation from RNA polymerase I promoter transcription initiation from RNA polymerase I promoter nucleolus organization cytoplasm organization cell population proliferation positive regulation of neuron projection development ribosome biogenesis positive regulation of transcription, DNA-templated homeostasis of number of cells RNA polymerase binding negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator regulation of DNA-templated transcription, initiation |
|
| TC0X00003021.mm.2 |
Tceal8 |
transcription elongation factor A (SII)-like 8 |
X |
-136168983 |
NM_001168578, NM_025703, BC027269 NM_001168578, NM_025703, BC027269 NM_001168578, NM_025703, BC027269 |
66684 |
18 |
nucleus WW domain binding |
|
| TC1900000099.mm.2 |
Cdca5 |
cell division cycle associated 5 |
19 |
6085096 |
NM_026410, BC052904 NM_026410, BC052904 |
67849 |
34 |
mitotic cell cycle mitotic cell cycle chromatin protein binding nucleus nucleus nucleoplasm chromosome cytoplasm double-strand break repair double-strand break repair cell cycle mitotic sister chromatid cohesion mitotic sister chromatid cohesion mitotic sister chromatid cohesion mitotic chromosome condensation mitotic metaphase plate congression mitotic metaphase plate congression positive regulation of exit from mitosis positive regulation of exit from mitosis protein-containing complex binding cell division regulation of cohesin loading regulation of cohesin loading |
|
| TC0200003109.mm.2 |
Hnmt |
histamine N-methyltransferase |
2 |
-24002912 |
NM_080462, BC033928 NM_080462, BC033928 |
140483 |
21 |
regulation of neurotransmitter levels histamine metabolic process histamine catabolic process nucleoplasm cytoplasm centrosome cytosol methyltransferase activity N-methyltransferase activity transferase activity methylation neuron projection histamine N-methyltransferase activity |
00340 |
| TC0100003610.mm.2 |
Fh1 |
fumarate hydratase 1 |
1 |
-175601377 |
NM_010209, BC006048 NM_010209, BC006048 |
14194 |
55 |
urea cycle negative regulation of histone H3-K36 methylation regulation of arginine metabolic process catalytic activity fumarate hydratase activity fumarate hydratase activity fumarate hydratase activity nucleus chromosome cytoplasm mitochondrion mitochondrion mitochondrion cytosol tricarboxylic acid cycle tricarboxylic acid cycle fumarate metabolic process fumarate metabolic process fumarate metabolic process malate metabolic process malate metabolic process DNA repair cellular response to DNA damage stimulus lyase activity site of double-strand break histone binding tricarboxylic acid cycle enzyme complex homeostasis of number of cells within a tissue positive regulation of cold-induced thermogenesis positive regulation of double-strand break repair via nonhomologous end joining |
00020 01100 05200 05211 |
| TC0900000254.mm.2 |
Thyn1 |
thymocyte nuclear protein 1 |
9 |
26999676 |
NM_144543, BC016594 NM_144543, BC016594 |
77862 |
22 |
molecular_function nucleus nucleus biological_process |
|
| TC0700000647.mm.2 |
Pepd |
peptidase D |
7 |
34912406 |
NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973 NM_008820, BC086644, BC131945, BC131973 |
18624 |
40 |
aminopeptidase activity peptidase activity peptidase activity metallopeptidase activity hydrolase activity dipeptidase activity manganese ion binding collagen catabolic process metal ion binding proline dipeptidase activity |
|
| TC1400002641.mm.2 |
Ednrb |
endothelin receptor type B |
14 |
-103814614, -103814614 |
NM_001136061, NM_001276296, NM_007904, BC026553 NM_001136061, NM_001276296, NM_007904, BC026553 NM_001136061, NM_001276296, NM_007904, BC026553 NM_001136061, NM_001276296, NM_007904, BC026553 |
13618 |
243 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II neural crest cell migration positive regulation of protein phosphorylation G protein-coupled receptor activity endothelin receptor activity endothelin receptor activity endothelin receptor activity protein binding plasma membrane regulation of pH signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration peripheral nervous system development posterior midgut development regulation of blood pressure regulation of blood pressure positive regulation of cell population proliferation negative regulation of neuron maturation vein smooth muscle contraction membrane integral component of membrane peptide hormone binding sensory perception of pain calcium-mediated signaling cGMP-mediated signaling melanocyte differentiation melanocyte differentiation melanocyte differentiation regulation of fever generation type 1 angiotensin receptor binding nuclear membrane negative regulation of cellular protein metabolic process response to lipopolysaccharide enteric smooth muscle cell differentiation positive regulation of urine volume positive regulation of renal sodium excretion epithelial fluid transport vasoconstriction vasodilation negative regulation of apoptotic process pigmentation pigmentation membrane raft developmental pigmentation macrophage chemotaxis response to pain enteric nervous system development enteric nervous system development regulation of epithelial cell proliferation regulation of sensory perception of pain positive regulation of penile erection endothelin receptor signaling pathway response to endothelin |
04020 04080 04916 |
| TC0X00002269.mm.2 |
Arhgef6 |
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
X |
-57231484, -57231484 |
NM_152801, BC156697 NM_152801, BC156697 |
73341 |
35 |
guanyl-nucleotide exchange factor activity protein binding cell-cell junction lamellipodium lamellipodium assembly regulation of Rho protein signal transduction intracellular signal transduction cell projection |
04810 05212 |
| TC0200002474.mm.2 |
Srsf6 |
serine and arginine-rich splicing factor 6 |
2 |
162931507 |
NM_026499, BC012039 NM_026499, BC012039 |
67996 |
30 |
alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding mRNA binding protein binding nucleus mRNA splice site selection mRNA splice site selection mRNA processing RNA splicing negative regulation of gene expression regulation of keratinocyte proliferation nuclear speck nuclear speck pre-mRNA binding negative regulation of keratinocyte differentiation negative regulation of mRNA splicing, via spliceosome positive regulation of epithelial cell proliferation involved in lung morphogenesis negative regulation of cell death regulation of wound healing negative regulation of type B pancreatic cell apoptotic process |
03040 |
| TC1300001131.mm.2 |
Mrps27 |
mitochondrial ribosomal protein S27 |
13 |
99344785 |
NM_173757, BC049149 NM_173757, BC049149 |
218506 |
26 |
tRNA binding RNA binding protein binding nucleolus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial small ribosomal subunit ribosome regulation of translation cell population proliferation rRNA binding positive regulation of mitochondrial translation mitochondrial ribosome binding |
|
| TC0500001894.mm.2 |
Cyp51 |
cytochrome P450, family 51 |
5 |
-4080673 |
NM_020010, BC031813 NM_020010, BC031813 |
13121 |
55 |
monooxygenase activity iron ion binding endoplasmic reticulum lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process sterol 14-demethylase activity sterol 14-demethylase activity membrane integral component of membrane sterol metabolic process sterol biosynthetic process oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen heme binding cholesterol biosynthetic process via 24,25-dihydrolanosterol negative regulation of protein catabolic process intracellular membrane-bounded organelle metal ion binding negative regulation of protein secretion negative regulation of amyloid-beta clearance |
00100 01100 |
| TC0900002115.mm.2 |
Sc5d |
sterol-C5-desaturase |
9 |
-42254176 |
NM_172769, BC024132 NM_172769, BC024132 |
235293 |
30 |
C-5 sterol desaturase activity C-5 sterol desaturase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process steroid metabolic process lipid biosynthetic process membrane integral component of membrane sterol biosynthetic process oxidoreductase activity cholesterol biosynthetic process via lathosterol cholesterol biosynthetic process via lathosterol intracellular membrane-bounded organelle |
00100 01100 |
| TC1000002443.mm.2 |
Pwp2 |
PWP2 periodic tryptophan protein homolog (yeast) |
10 |
-78170909 |
NM_029546, BC112325, BC128480 NM_029546, BC112325, BC128480 NM_029546, BC112325, BC128480 |
110816 |
23 |
ribosomal small subunit assembly maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus small-subunit processome Pwp2p-containing subcomplex of 90S preribosome |
03008 |
| TC0600001440.mm.2 |
Pianp |
PILR alpha associated neural protein |
6 |
124998609, 124996719, 124998436 |
NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170 NM_001145926, NM_001145927, NM_175696, BC065170 |
319352 |
18 |
molecular_function biological_process membrane integral component of membrane basolateral plasma membrane regulation of immune response |
|
| TC1100001730.mm.2 |
Itgb3 |
integrin beta 3 |
11 |
104607999 |
NM_016780, BC125518, BC125520 NM_016780, BC125518, BC125520 NM_016780, BC125518, BC125520 |
16416 |
424 |
positive regulation of endothelial cell proliferation positive regulation of cell-matrix adhesion fibronectin binding fibronectin binding protease binding positive regulation of leukocyte migration protein disulfide isomerase activity protein kinase C binding integrin binding integrin binding integrin binding protein binding nucleus nucleoplasm plasma membrane cell-cell junction focal adhesion focal adhesion focal adhesion cell-substrate junction assembly cell adhesion cell-matrix adhesion cell-matrix adhesion cell-matrix adhesion integrin-mediated signaling pathway regulation of G protein-coupled receptor signaling pathway integrin complex integrin complex external side of plasma membrane cell surface cell surface cell surface positive regulation of endothelial cell migration positive regulation of gene expression negative regulation of macrophage derived foam cell differentiation positive regulation of fibroblast migration positive regulation of fibroblast migration negative regulation of lipid storage smooth muscle cell migration positive regulation of smooth muscle cell migration membrane integral component of membrane apical plasma membrane apical plasma membrane cell migration fibroblast growth factor binding enzyme binding enzyme binding C-X3-C chemokine binding cell junction platelet activation regulation of cell migration positive regulation of cell migration lamellipodium membrane filopodium membrane microvillus membrane cell-substrate adhesion insulin-like growth factor I binding activation of protein kinase activity negative regulation of lipid transport ruffle membrane regulation of protein localization regulation of actin cytoskeleton organization protein-containing complex cell adhesion mediated by integrin cell adhesion mediated by integrin positive regulation of cell adhesion mediated by integrin positive regulation of osteoblast proliferation heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading integrin alpha9-beta1 complex integrin alphav-beta3 complex alphav-beta3 integrin-PKCalpha complex alphav-beta3 integrin-PKCalpha complex alphav-beta3 integrin-IGF-1-IGF1R complex alphav-beta3 integrin-HMGB1 complex cellular response to platelet-derived growth factor stimulus apolipoprotein A-I-mediated signaling pathway neuregulin binding melanosome identical protein binding cell projection vascular endothelial growth factor receptor 2 binding receptor complex apoptotic cell clearance apoptotic cell clearance synapse postsynaptic membrane positive regulation of osteoclast differentiation positive regulation of angiogenesis positive regulation of bone resorption positive regulation of bone resorption viral entry into host cell platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation positive regulation of smooth muscle cell proliferation cell projection morphogenesis positive regulation of peptidyl-tyrosine phosphorylation negative regulation of lipoprotein metabolic process cell adhesion molecule binding extracellular matrix binding negative chemotaxis regulation of release of sequestered calcium ion into cytosol regulation of serotonin uptake negative regulation of cell death regulation of protein tyrosine kinase activity fibrinogen binding fibrinogen binding positive regulation of ERK1 and ERK2 cascade platelet aggregation alpha9-beta1 integrin-ADAM8 complex positive regulation of glomerular mesangial cell proliferation glutamatergic synapse glutamatergic synapse regulation of postsynaptic neurotransmitter receptor internalization integral component of synaptic membrane positive regulation of substrate adhesion-dependent cell spreading positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway regulation of extracellular matrix organization negative regulation of low-density lipoprotein receptor activity positive regulation of T cell migration |
04145 04380 04510 04512 04640 04810 05410 05412 05414 |
| TC0X00002643.mm.2 |
Eif2s3x |
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked |
X |
-94188708 |
NM_012010, BC063755, BC139234, BC139235 NM_012010, BC063755, BC139234, BC139235 NM_012010, BC063755, BC139234, BC139235 NM_012010, BC063755, BC139234, BC139235 |
26905 |
29 |
tRNA binding nucleotide binding formation of translation preinitiation complex translation initiation factor activity translation initiation factor activity GTPase activity GTP binding cytoplasm cytosol eukaryotic translation initiation factor 2 complex eukaryotic translation initiation factor 2 complex translation translational initiation translation factor activity, RNA binding hydrolase activity positive regulation of translational fidelity |
03013 |
| TC0500000260.mm.2 |
Insig1 |
insulin induced gene 1 |
5 |
28071411 |
NM_153526, BC132167, BC132499 NM_153526, BC132167, BC132499 NM_153526, BC132167, BC132499 |
231070 |
37 |
protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lipid metabolic process triglyceride metabolic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process response to sterol depletion oxysterol binding steroid metabolic process cholesterol metabolic process lipid binding negative regulation of steroid biosynthetic process membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process cellular response to insulin stimulus SREBP signaling pathway SREBP signaling pathway SREBP-SCAP-Insig complex SREBP-SCAP-Insig complex cellular response to sterol SREBP-SCAP complex retention in endoplasmic reticulum SREBP-SCAP complex retention in endoplasmic reticulum inner ear morphogenesis middle ear morphogenesis cholesterol homeostasis negative regulation of fat cell differentiation negative regulation of fatty acid biosynthetic process roof of mouth development cranial suture morphogenesis negative regulation of protein exit from endoplasmic reticulum negative regulation of cargo loading into COPII-coated vesicle |
|
| TC0700003024.mm.2 |
Grwd1 |
glutamate-rich WD repeat containing 1 |
7 |
-45825225, -45825222 |
NM_153419, BC028896 NM_153419, BC028896 |
101612 |
19 |
chromatin binding DNA replication origin binding nucleus nucleoplasm chromosome nucleolus cytosol DNA replication nucleosome assembly nucleosome disassembly protein-containing complex histone binding |
|
| TC0700002980.mm.2 |
Prmt1 |
protein arginine N-methyltransferase 1 |
7 |
-44976754 |
NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 NM_001252476, NM_001252477, NM_019830, NR_045521, BC002249, BC051953, BC062964 |
15469 |
104 |
in utero embryonic development protein binding nucleus nucleus cytoplasm cytosol protein methylation methyltransferase activity N-methyltransferase activity protein methyltransferase activity protein methyltransferase activity positive regulation of cell population proliferation methyl-CpG binding histone-arginine N-methyltransferase activity membrane protein-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity [cytochrome c]-arginine N-methyltransferase activity histone methylation transferase activity peptidyl-arginine methylation enzyme binding peptidyl-arginine methylation, to asymmetrical-dimethyl arginine peptidyl-arginine methylation, to asymmetrical-dimethyl arginine snoRNP binding neuron projection development methylation protein-containing complex methylosome protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity peptidyl-arginine omega-N-methylation histone methyltransferase activity histone methyltransferase activity identical protein binding histone H4-R3 methylation histone H4-R3 methylation histone methyltransferase activity (H4-R3 specific) positive regulation of erythrocyte differentiation regulation of megakaryocyte differentiation negative regulation of megakaryocyte differentiation positive regulation of hemoglobin biosynthetic process mitogen-activated protein kinase p38 binding protein homooligomerization positive regulation of p38MAPK cascade S-adenosyl-L-methionine binding |
|
| TC1100004051.mm.2 |
Cd300lb |
CD300 molecule like family member B |
11 |
-114922778 |
NM_199221, CD300, BC160263 NM_199221, CD300, BC160263 NM_199221, CD300, BC160263 |
217304 |
21 |
immune system process neutrophil mediated immunity transmembrane signaling receptor activity protein binding plasma membrane membrane integral component of membrane positive regulation of mast cell activation cellular response to lipopolysaccharide |
|
| TC1200002077.mm.2 |
Entpd5 |
ectonucleoside triphosphate diphosphohydrolase 5 |
12 |
-84373875, -84373875 |
NM_001026214, NM_001286049, NM_001286058, NM_007647, BC015247 NM_001026214, NM_001286049, NM_001286058, NM_007647, BC015247 NM_001026214, NM_001286049, NM_001286058, NM_007647, BC015247 NM_001026214, NM_001286049, NM_001286058, NM_007647, BC015247 NM_001026214, NM_001286049, NM_001286058, NM_007647, BC015247 |
12499 |
29 |
guanosine-diphosphatase activity guanosine-diphosphatase activity guanosine-diphosphatase activity extracellular region endoplasmic reticulum endoplasmic reticulum lumen protein N-linked glycosylation nucleoside diphosphate catabolic process regulation of phosphatidylinositol 3-kinase signaling membrane hydrolase activity nucleoside-diphosphatase activity nucleoside-diphosphatase activity uridine-diphosphatase activity uridine-diphosphatase activity uridine-diphosphatase activity positive regulation of glycolytic process ATP metabolic process 'de novo' posttranslational protein folding |
00230 00240 |
| TC1800000583.mm.2 |
Slc12a2 |
solute carrier family 12, member 2 |
18 |
57878677 |
NM_009194 |
20496 |
193 |
transporter activity protein binding cytosol plasma membrane ion transport potassium ion transport sodium ion transport chloride transport cellular sodium ion homeostasis cell volume homeostasis cell volume homeostasis hyperosmotic response gamma-aminobutyric acid signaling pathway sodium:potassium:chloride symporter activity sodium:potassium:chloride symporter activity sodium:potassium:chloride symporter activity ammonium transmembrane transporter activity ammonium transmembrane transporter activity basal plasma membrane T cell chemotaxis T cell chemotaxis potassium ion transmembrane transporter activity symporter activity cation:chloride symporter activity potassium:chloride symporter activity ammonium transport ammonium transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane lateral plasma membrane protein kinase binding cellular potassium ion homeostasis transepithelial chloride transport cellular chloride ion homeostasis cytoplasmic vesicle membrane multicellular organism growth maintenance of blood-brain barrier sodium ion transmembrane transport cellular response to potassium ion cell projection neuron projection neuronal cell body neuronal cell body cell body positive regulation of cell volume metal ion transmembrane transporter activity detection of mechanical stimulus involved in sensory perception of sound chaperone binding Hsp90 protein binding chloride ion homeostasis potassium ion homeostasis sodium ion homeostasis transmembrane transport branching involved in mammary gland duct morphogenesis mammary duct terminal end bud growth negative regulation of vascular wound healing transepithelial ammonium transport cell periphery cell periphery inorganic anion import across plasma membrane inorganic cation import across plasma membrane sodium ion import across plasma membrane regulation of spontaneous synaptic transmission regulation of spontaneous synaptic transmission regulation of spontaneous synaptic transmission chloride transmembrane transport chloride transmembrane transport positive regulation of aspartate secretion regulation of matrix metallopeptidase secretion potassium ion import across plasma membrane potassium ion import across plasma membrane cellular response to chemokine cellular response to chemokine |
04970 04972 |
| TC0200001144.mm.2 |
Gm14461 |
predicted gene 14461 |
2 |
78237546 |
NM_177843 |
329436 |
10 |
|
|
| TC0700004363.mm.2 |
Rgs10 |
regulator of G-protein signalling 10 |
7 |
-128373624 |
NM_026418, BC109178 NM_026418, BC109178 |
67865 |
37 |
G-protein alpha-subunit binding GTPase activator activity protein binding nucleus cytoplasm cytosol G protein-coupled acetylcholine receptor signaling pathway regulation of G protein-coupled receptor signaling pathway negative regulation of signal transduction neuronal cell body dendritic spine positive regulation of GTPase activity axon terminus |
|
| TC1600000763.mm.2 |
Cpox |
coproporphyrinogen oxidase |
16 |
58670207 |
NM_007757, BC017680 NM_007757, BC017680 |
12892 |
42 |
coproporphyrinogen oxidase activity coproporphyrinogen oxidase activity coproporphyrinogen oxidase activity structural constituent of eye lens P-type sodium:potassium-exchanging ATPase activity cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial intermembrane space mitochondrial intermembrane space cytosol porphyrin-containing compound biosynthetic process protoporphyrinogen IX biosynthetic process protoporphyrinogen IX biosynthetic process heme biosynthetic process heme biosynthetic process potassium ion transport sodium ion transport membrane oxidoreductase activity identical protein binding protein homodimerization activity |
00860 01100 |
| TC0800003008.mm.2 |
Gcsh |
glycine cleavage system protein H (aminomethyl carrier) |
8 |
-116981966 |
NM_026572, BC014745 NM_026572, BC014745 |
68133 |
19 |
aminomethyltransferase activity cytoplasm mitochondrion mitochondrion mitochondrion glycine cleavage complex protein lipoylation protein lipoylation glycine decarboxylation via glycine cleavage system glycine decarboxylation via glycine cleavage system enzyme binding |
|
| TC0600000839.mm.2 |
Polr1a |
polymerase (RNA) I polypeptide A |
6 |
71909052 |
NM_009088, BC053744 NM_009088, BC053744 |
20019 |
28 |
RNA polymerase I activity DNA binding chromatin binding DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity protein binding nucleus nucleoplasm chromosome RNA polymerase I complex RNA polymerase I complex RNA polymerase I complex transcription, DNA-templated zinc ion binding rRNA transcription transferase activity nucleotidyltransferase activity metal ion binding negative regulation of protein localization to nucleolus |
00230 00240 01100 03020 |
| TC0800001106.mm.2 |
Herpud1 |
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
8 |
94386428 |
NM_022331, BC013523 NM_022331, BC013523 |
64209 |
48 |
protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process cellular calcium ion homeostasis response to unfolded protein membrane integral component of membrane ubiquitin-dependent ERAD pathway endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response retrograde protein transport, ER to cytosol regulation of protein ubiquitination endoplasmic reticulum calcium ion homeostasis endoplasmic reticulum calcium ion homeostasis response to endoplasmic reticulum stress response to endoplasmic reticulum stress negative regulation of cysteine-type endopeptidase activity involved in apoptotic process endoplasmic reticulum quality control compartment ion channel binding ion channel binding protein targeting to ER regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway regulation of ER-associated ubiquitin-dependent protein catabolic process regulation of ER-associated ubiquitin-dependent protein catabolic process positive regulation of ER-associated ubiquitin-dependent protein catabolic process Lewy body core ubiquitin ligase-substrate adaptor activity negative regulation of intrinsic apoptotic signaling pathway |
04141 |
| TC0300000968.mm.2 |
Prkab2 |
protein kinase, AMP-activated, beta 2 non-catalytic subunit |
3 |
97658211 |
NM_182997, BC060228 NM_182997, BC060228 |
108097 |
46 |
AMP-activated protein kinase activity AMP-activated protein kinase activity nucleus nucleoplasm cytoplasm cytoplasm cytosol cAMP-dependent protein kinase complex lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process signal transduction apical plasma membrane enzyme binding protein kinase binding protein kinase binding nucleotide-activated protein kinase complex nucleotide-activated protein kinase complex identical protein binding regulation of catalytic activity regulation of primary metabolic process positive regulation of cold-induced thermogenesis |
04910 04920 05410 |
| TC0400000507.mm.2 |
Nans |
N-acetylneuraminic acid synthase (sialic acid synthase) |
4 |
46489328 |
NM_053179, BC003307, BC057977 NM_053179, BC003307, BC057977 NM_053179, BC003307, BC057977 |
94181 |
19 |
catalytic activity cytoplasm cytosol carbohydrate biosynthetic process transferase activity N-acylneuraminate-9-phosphate synthase activity N-acylneuraminate-9-phosphate synthase activity glycosylation |
00520 01100 |
| TC0200002729.mm.2 |
|
|
|
|
NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 NM_001099308, NM_001164689, NM_001177480 |
|
|
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific cellular_component regulation of transcription by RNA polymerase II |
|
| TC0300003106.mm.2 |
Prkacb |
protein kinase, cAMP dependent, catalytic, beta |
3 |
-146729578, -146729578, -146729578, -146729578 |
NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 NM_001164198, NM_001164199, NM_001164200, NM_011100, BC054533 |
18749 |
67 |
nucleotide binding magnesium ion binding magnesium ion binding neural tube closure protein kinase activity protein serine/threonine kinase activity cAMP-dependent protein kinase activity cAMP-dependent protein kinase activity ATP binding ATP binding nucleus nucleus cytoplasm centrosome cytosol cytosol plasma membrane cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex protein phosphorylation protein phosphorylation G protein-coupled receptor signaling pathway adenylate cyclase-modulating G protein-coupled receptor signaling pathway protein kinase A signaling membrane kinase activity phosphorylation transferase activity ubiquitin protein ligase binding protein kinase A regulatory subunit binding perinuclear region of cytoplasm negative regulation of meiotic cell cycle regulation of protein processing ciliary base negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning |
04010 04020 04062 04114 04210 04270 04310 04340 04540 04720 04740 04742 04910 04912 04914 04916 04962 04970 04971 04976 05020 05146 05414 |
| TC0500001517.mm.2 |
Vkorc1l1 |
vitamin K epoxide reductase complex, subunit 1-like 1 |
5 |
129942108 |
NM_001001327, NM_001286382, NM_027121, BC085133, BC125315, BC138132 NM_001001327, NM_001286382, NM_027121, BC085133, BC125315, BC138132 NM_001001327, NM_001286382, NM_027121, BC085133, BC125315, BC138132 NM_001001327, NM_001286382, NM_027121, BC085133, BC125315, BC138132 NM_001001327, NM_001286382, NM_027121, BC085133, BC125315, BC138132 NM_001001327, NM_001286382, NM_027121, BC085133, BC125315, BC138132 |
69568 |
25 |
endoplasmic reticulum endoplasmic reticulum membrane membrane integral component of membrane oxidoreductase activity peptidyl-glutamic acid carboxylation peptidyl-glutamic acid carboxylation cellular response to oxidative stress vitamin K metabolic process vitamin K metabolic process vitamin K metabolic process vitamin-K-epoxide reductase (warfarin-sensitive) activity vitamin-K-epoxide reductase (warfarin-sensitive) activity vitamin-K-epoxide reductase (warfarin-sensitive) activity quinone binding |
|
| TC1700002167.mm.2 |
Polh |
polymerase (DNA directed), eta (RAD 30 related) |
17 |
-46171354 |
NM_030715, BC128366 NM_030715, BC128366 |
80905 |
46 |
DNA synthesis involved in DNA repair DNA binding damaged DNA binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity nucleus nucleoplasm replication fork cytosol DNA replication DNA repair pyrimidine dimer repair postreplication repair cellular response to DNA damage stimulus response to radiation response to UV-C transferase activity nucleotidyltransferase activity site of double-strand break error-prone translesion synthesis metal ion binding cellular response to UV-C cellular response to UV-C DNA biosynthetic process |
|
| TC1000002212.mm.2 |
Mcu |
mitochondrial calcium uniporter |
10 |
-59446983 |
NM_001033259, BC139254, BC139257 NM_001033259, BC139254, BC139257 NM_001033259, BC139254, BC139257 |
215999 |
80 |
calcium channel activity calcium channel activity protein binding mitochondrion mitochondrion mitochondrial inner membrane ion transport calcium ion transport mitochondrial calcium ion transmembrane transport mitochondrial calcium ion transmembrane transport uniporter activity uniporter activity membrane integral component of membrane calcium-mediated signaling integral component of mitochondrial inner membrane integral component of mitochondrial inner membrane positive regulation of insulin secretion calcium channel complex calcium channel complex calcium import into the mitochondrion calcium import into the mitochondrion glucose homeostasis identical protein binding identical protein binding protein complex oligomerization mitochondrial calcium ion homeostasis mitochondrial calcium ion homeostasis positive regulation of mitochondrial calcium ion concentration positive regulation of mitochondrial calcium ion concentration calcium ion transmembrane transport positive regulation of neutrophil chemotaxis positive regulation of mitochondrial fission actin filament reorganization uniplex complex uniplex complex |
|
| TC1100002001.mm.2 |
Slc26a11 |
solute carrier family 26, member 11 |
11 |
119355556 |
NM_178743, BC132493, BC137897 NM_178743, BC132493, BC137897 NM_178743, BC132493, BC137897 |
268512 |
17 |
nucleoplasm lysosome lysosomal membrane endoplasmic reticulum Golgi apparatus plasma membrane integral component of plasma membrane ion transport secondary active sulfate transmembrane transporter activity sulfate transport anion transmembrane transporter activity sulfate transmembrane transporter activity anion:anion antiporter activity membrane integral component of membrane intracellular membrane-bounded organelle transmembrane transport |
|
| TC1700002497.mm.2 |
Ndc80 |
NDC80 kinetochore complex component |
17 |
-71496099 |
NM_023294, BC020131 NM_023294, BC020131 |
67052 |
29 |
mitotic sister chromatid segregation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed nuclear chromosome outer kinetochore protein binding nucleus nucleoplasm chromosome cytoplasm centrosome centrosome cell cycle mitotic spindle organization spindle assembly involved in female meiosis I spindle assembly involved in female meiosis I chromosome segregation G2/MI transition of meiotic cell cycle attachment of spindle microtubules to kinetochore cyclin binding Ndc80 complex Ndc80 complex regulation of protein stability identical protein binding centrosome duplication cell division metaphase plate congression attachment of mitotic spindle microtubules to kinetochore attachment of mitotic spindle microtubules to kinetochore kinetochore organization kinetochore organization positive regulation of mitotic cell cycle spindle assembly checkpoint positive regulation of protein localization to kinetochore |
|
| TC1700001969.mm.2 |
Tcf19 |
transcription factor 19 |
17 |
-35512734 |
NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617 NM_001163763, NM_001163764, NM_025674, BC004617 |
106795 |
29 |
G1/S transition of mitotic cell cycle nucleus nucleus regulation of gene expression regulation of gene expression type B pancreatic cell proliferation |
|
| TC1000002586.mm.2 |
Appl2 |
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
10 |
-83600033 |
NM_145220, BC048906 NM_145220, BC048906 |
216190 |
34 |
ruffle phosphatidylserine binding diet induced thermogenesis protein binding nucleus cytoplasm cytoplasm endosome plasma membrane plasma membrane protein import into nucleus cell cycle transforming growth factor beta receptor signaling pathway cell population proliferation cold acclimation endosome membrane endosome membrane regulation of fibroblast migration membrane signaling small GTPase binding cytoplasmic vesicle vesicle early phagosome ruffle membrane adiponectin-activated signaling pathway regulation of toll-like receptor 4 signaling pathway phosphatidylinositol binding cellular response to hepatocyte growth factor stimulus early phagosome membrane glucose homeostasis identical protein binding protein homodimerization activity cell projection macropinosome protein-containing complex binding regulation of innate immune response negative regulation of fatty acid oxidation negative regulation of glucose import negative regulation of glucose import negative regulation of neurogenesis protein homotetramerization positive regulation of phagocytosis, engulfment positive regulation of cold-induced thermogenesis negative regulation of cytokine production involved in inflammatory response negative regulation of cellular response to insulin stimulus positive regulation of macropinocytosis positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis regulation of G1/S transition of mitotic cell cycle negative regulation of neural precursor cell proliferation |
|
| TC1600001025.mm.2 |
Smim11 |
small integral membrane protein 11 |
16 |
92301302 |
NM_138743, BC005668 NM_138743, BC005668 |
68936 |
18 |
molecular_function cellular_component biological_process membrane integral component of membrane |
|
| TC1500000710.mm.2 |
Adsl |
adenylosuccinate lyase |
15 |
80948489 |
NM_009634, BC020187 NM_009634, BC020187 |
11564 |
34 |
catalytic activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity mitochondrion cytosol cytosol purine nucleotide metabolic process purine nucleotide biosynthetic process AMP biosynthetic process AMP biosynthetic process response to nutrient aerobic respiration purine ribonucleotide biosynthetic process ribonucleoside monophosphate biosynthetic process lyase activity protein-containing complex identical protein binding 'de novo' AMP biosynthetic process (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity |
00230 00250 01100 |
| TC0200001663.mm.2 |
Nop10 |
NOP10 ribonucleoprotein |
2 |
112261925 |
NM_025403, BC028497 NM_025403, BC028497 |
66181 |
16 |
snoRNA guided rRNA pseudouridine synthesis pseudouridine synthesis RNA binding protein binding nucleus telomerase holoenzyme complex rRNA processing telomere maintenance via telomerase nuclear body snoRNA binding rRNA pseudouridine synthesis snRNA pseudouridine synthesis box H/ACA snoRNP complex box H/ACA snoRNP complex box H/ACA snoRNA binding box H/ACA snoRNA binding ribosome biogenesis telomerase RNA binding telomerase RNA binding box H/ACA telomerase RNP complex box H/ACA telomerase RNP complex |
03008 |
| TC1800000535.mm.2 |
Snx24 |
sorting nexing 24 |
18 |
53245624 |
NM_029394, BC051168 NM_029394, BC051168 |
69226 |
15 |
cellular_component biological_process lipid binding phosphatidylinositol-5-phosphate binding protein transport membrane cytoplasmic vesicle phosphatidylinositol-3-phosphate binding phosphatidylinositol binding phosphatidylinositol-4-phosphate binding phosphatidylinositol phosphate binding |
|
| TC1200001908.mm.2 |
Dhrs7 |
dehydrogenase/reductase (SDR family) member 7 |
12 |
-72650352 |
NM_025522, BC016189 NM_025522, BC016189 |
66375 |
18 |
biological_process oxidoreductase activity |
|
| TC0X00002266.mm.2 |
|
|
|
|
NM_146234, NR_039576, BC032271 NM_146234, NR_039576, BC032271 NM_146234, NR_039576, BC032271 |
|
|
Golgi membrane cytoplasm endosome early endosome early endosome endoplasmic reticulum Golgi apparatus Golgi apparatus plasma membrane plasma membrane cation transport cobalt ion transport copper ion transport iron ion transport cobalt ion transmembrane transporter activity ferrous iron transmembrane transporter activity magnesium ion transmembrane transporter activity magnesium ion transport membrane integral component of membrane inorganic cation transmembrane transporter activity inorganic cation transmembrane transporter activity integral component of endoplasmic reticulum membrane membrane insertase activity protein insertion into ER membrane by stop-transfer membrane-anchor sequence tail-anchored membrane protein insertion into ER membrane EMC complex EMC complex |
|
| TC0500000434.mm.2 |
Lyar |
Ly1 antibody reactive clone |
5 |
38220481 |
NM_025281, BC116923, BC116927 NM_025281, BC116923, BC116927 NM_025281, BC116923, BC116927 |
17089 |
30 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II photoreceptor outer segment immune system process DNA binding DNA binding nucleus nucleoplasm nucleolus nucleolus nucleolus cytoplasm rRNA processing rRNA processing activating transcription factor binding identical protein binding cell projection innate immune response negative regulation of innate immune response positive regulation of transcription by RNA polymerase I metal ion binding erythrocyte development positive regulation of phagocytosis transcription regulator inhibitor activity |
|
| TC1000000566.mm.2 |
Lrrc20 |
leucine rich repeat containing 20 |
10 |
61475832 |
NM_153542, BC036304 NM_153542, BC036304 |
216011 |
15 |
molecular_function cellular_component biological_process |
|
| TC0900001987.mm.2 |
Fli1 |
Friend leukemia integration 1 |
9 |
-32422203 |
NM_008026, BC138791, BC138792 NM_008026, BC138791, BC138792 NM_008026, BC138791, BC138792 |
14247 |
133 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity nucleus nucleus nucleus nucleoplasm cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II blood circulation animal organ morphogenesis cellular process nuclear body cell differentiation megakaryocyte development sequence-specific DNA binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| TC0500000289.mm.2 |
Selenoi |
selenoprotein I |
5 |
30232580 |
NM_027652, BC106097, BC115783, BC117551 NM_027652, BC106097, BC115783, BC117551 NM_027652, BC106097, BC115783, BC117551 NM_027652, BC106097, BC115783, BC117551 |
28042 |
20 |
ethanolaminephosphotransferase activity ethanolaminephosphotransferase activity endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid metabolic process phosphatidylethanolamine biosynthetic process phosphatidylethanolamine biosynthetic process phospholipid biosynthetic process membrane integral component of membrane transferase activity phosphotransferase activity, for other substituted phosphate groups metal ion binding |
00564 00565 01100 |
| TC0200002478.mm.2 |
Mybl2 |
myeloblastosis oncogene-like 2 |
2 |
163054634 |
NM_008652, BC050842 NM_008652, BC050842 |
17865 |
77 |
mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding nucleus nucleus nucleoplasm nucleoplasm regulation of transcription, DNA-templated Myb complex positive regulation of neuron apoptotic process positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mitotic spindle assembly cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding |
|
| TC1400002150.mm.2 |
Ska3 |
spindle and kinetochore associated complex subunit 3 |
14 |
-57806560 |
NM_198605, BC117500, BC117501 NM_198605, BC117500, BC117501 NM_198605, BC117500, BC117501 |
219114 |
19 |
mitotic cell cycle mitotic cell cycle chromosome, centromeric region kinetochore condensed chromosome outer kinetochore condensed chromosome outer kinetochore molecular_function chromosome cytoplasm centrosome cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cell cycle chromosome segregation chromosome segregation regulation of microtubule polymerization or depolymerization cell division mitotic spindle |
|
| TC0X00002671.mm.2 |
Las1l |
LAS1-like (S. cerevisiae) |
X |
-95935312, -95935320 |
NM_152822, BC141155 NM_152822, BC141155 |
76130 |
25 |
maturation of 5.8S rRNA maturation of LSU-rRNA nucleus cytoplasm rRNA processing preribosome, large subunit precursor MLL1 complex |
|
| TC1600001390.mm.2 |
Rfc4 |
replication factor C (activator 1) 4 |
16 |
-23113947 |
NM_145480, BC003335 NM_145480, BC003335 |
106344 |
29 |
nucleotide binding DNA binding DNA clamp loader activity DNA clamp loader activity ATP binding nucleus nucleoplasm DNA replication factor C complex DNA replication factor C complex DNA replication DNA-dependent DNA replication DNA repair single-stranded DNA helicase activity enzyme binding Ctf18 RFC-like complex Elg1 RFC-like complex positive regulation of DNA-directed DNA polymerase activity |
03030 03420 03430 |
| TC0X00003431.mm.2 |
Naa10 |
N(alpha)-acetyltransferase 10, NatA catalytic subunit |
X |
-73916869 |
NM_001177965, NM_019870, BC027219 NM_001177965, NM_019870, BC027219 NM_001177965, NM_019870, BC027219 |
56292 |
31 |
peptide alpha-N-acetyltransferase activity protein binding nucleus nucleolus cytoplasm cytoplasm cytosol protein acetylation N-terminal protein amino acid acetylation N-acetyltransferase activity acetyltransferase activity transferase activity transferase activity, transferring acyl groups N-terminal peptidyl-serine acetylation N-terminal peptidyl-glutamic acid acetylation NatA complex NatA complex ribosome binding peptide-serine-N-acetyltransferase activity peptide-glutamate-N-acetyltransferase activity negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric |
|
| TC1100001156.mm.2 |
Aldoc |
aldolase C, fructose-bisphosphate |
11 |
78324197, 78323072 |
NM_009657, BC004802, BC008184 NM_009657, BC004802, BC008184 NM_009657, BC004802, BC008184 |
11676 |
84 |
catalytic activity fructose-bisphosphate aldolase activity fructose-bisphosphate aldolase activity fructose-bisphosphate aldolase activity cytoplasm mitochondrion cytosol glycolytic process apoptotic process aging cytoskeletal protein binding lyase activity fructose 1,6-bisphosphate metabolic process fructose 1,6-bisphosphate metabolic process axon identical protein binding protein-containing complex binding postsynaptic cytosol |
00010 00030 00051 01100 |
| TC1100003125.mm.2 |
Nlrp1b |
NLR family, pyrin domain containing 1B |
11 |
-71153101, -71153101 |
NM_001040696, NM_001162414, BC141354 NM_001040696, NM_001162414, BC141354 NM_001040696, NM_001162414, BC141354 |
637515 |
30 |
nucleotide binding immune system process ATP binding nucleus nucleoplasm cytoplasm cytosol activation of cysteine-type endopeptidase activity involved in apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process inflammatory response membrane enzyme binding protein domain specific binding protein catabolic process interleukin-1 alpha production interleukin-1 beta production interleukin-1 beta production regulation of apoptotic process innate immune response neuron apoptotic process defense response to virus inflammasome complex pyroptosis pyroptosis NLRP1 inflammasome complex self proteolysis antiviral innate immune response NLRP1 inflammasome complex assembly |
04621 |
| TC1100001973.mm.2 |
Birc5 |
baculoviral IAP repeat-containing 5 |
11 |
117849236 |
NM_001012273, NM_009689, BC004702 NM_001012273, NM_009689, BC004702 NM_001012273, NM_009689, BC004702 |
11799 |
215 |
G2/M transition of mitotic cell cycle microtubule cytoskeleton organization nuclear chromosome mitotic cytokinesis chromosome, centromeric region kinetochore condensed chromosome kinetochore cysteine-type endopeptidase inhibitor activity protein binding nucleus nucleus chromosome cytoplasm cytoplasm cytoplasm centriole cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cytoplasmic microtubule protein phosphorylation apoptotic process cell cycle chromosome segregation mitotic spindle assembly checkpoint regulation of mitotic cell cycle microtubule binding zinc ion binding embryo development negative regulation of peptidase activity tubulin binding apical plasma membrane enzyme binding peptidase inhibitor activity midbody interphase microtubule organizing center small GTPase binding protein-containing complex localization positive regulation of exit from mitosis chromosome passenger complex protein-containing complex identical protein binding protein homodimerization activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of neuron apoptotic process positive regulation of cell cycle negative regulation of transcription, DNA-templated positive regulation of mitotic cell cycle metal ion binding protein heterodimerization activity chaperone binding cell division establishment of chromosome localization regulation of cell cycle regulation of insulin secretion involved in cellular response to glucose stimulus regulation of type B pancreatic cell proliferation |
05200 05210 |
| TC0400002222.mm.2 |
Cibar1 |
CBY1 interacting BAR domain containing 1 |
4 |
-12153141 |
NM_026558, BC020162 NM_026558, BC020162 |
68099 |
19 |
protein binding phospholipid binding nucleus cytoplasm mitochondrial inner membrane centriole cytoskeleton cilium inner mitochondrial membrane organization cell projection organization limb morphogenesis limb morphogenesis ciliary transition zone ciliary basal body cell projection positive regulation of smoothened signaling pathway cilium assembly cilium assembly membrane organization ciliary base |
|
| TC1900000188.mm.2 |
Fads1 |
fatty acid desaturase 1 |
19 |
10182887 |
NM_146094, BC022139, BC026831, BC026848, BC063053 NM_146094, BC022139, BC026831, BC026848, BC063053 NM_146094, BC022139, BC026831, BC026848, BC063053 NM_146094, BC022139, BC026831, BC026848, BC063053 NM_146094, BC022139, BC026831, BC026848, BC063053 |
76267 |
35 |
nucleus mitochondrion endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process unsaturated fatty acid biosynthetic process cellular response to starvation membrane integral component of membrane linoleoyl-CoA desaturase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water arachidonic acid metabolic process long-chain fatty acid biosynthetic process intracellular membrane-bounded organelle acyl-CoA delta5-desaturase activity acyl-CoA delta5-desaturase activity |
01040 |
| TC1300000182.mm.2 |
|
|
|
|
NM_001195421, NM_175657, BC115448, BC152397 NM_001195421, NM_175657, BC115448, BC152397 NM_001195421, NM_175657, BC115448, BC152397 NM_001195421, NM_175657, BC115448, BC152397 |
|
|
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein domain specific binding protein-containing complex negative regulation of megakaryocyte differentiation |
|
| TC1300001564.mm.2 |
H4c18 |
H4 clustered histone 18 |
13 |
-21831791 |
NM_175657, BC115448, BC152397 NM_175657, BC115448, BC152397 NM_175657, BC115448, BC152397 |
319161 |
5 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein domain specific binding protein-containing complex negative regulation of megakaryocyte differentiation |
05322 |
| TC0X00002238.mm.2 |
Mospd1 |
motile sperm domain containing 1 |
X |
-53344593 |
NM_027409, BC018329, BC085100, BC100442 NM_027409, BC018329, BC085100, BC100442 NM_027409, BC018329, BC085100, BC100442 NM_027409, BC018329, BC085100, BC100442 |
70380 |
18 |
negative regulation of transcription by RNA polymerase II molecular_function nucleus cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus membrane integral component of membrane cell differentiation positive regulation of transcription by RNA polymerase II perinuclear region of cytoplasm |
|
| TC1100004219.mm.2 |
Alyref |
Aly/REF export factor |
11 |
-120594515 |
NM_011568, BC120588, BC137658 NM_011568, BC120588, BC137658 NM_011568, BC120588, BC137658 |
21681 |
39 |
nucleic acid binding single-stranded DNA binding RNA binding nucleus spliceosomal complex cytoplasm mRNA processing RNA splicing mRNA transport |
03013 03015 03040 |
| TC0700001980.mm.2 |
|
|
|
|
NM_023140, NR_033611, BC033506, BC087885 NM_023140, NR_033611, BC033506, BC087885 NM_023140, NR_033611, BC033506, BC087885 NM_023140, NR_033611, BC033506, BC087885 |
|
|
regulation of the force of heart contraction protein kinase C binding protein binding nucleus nucleus cytoplasm cytosol cellular iron ion homeostasis electron transfer activity negative regulation of cardiac muscle hypertrophy protein disulfide oxidoreductase activity Z disc dendrite identical protein binding [2Fe-2S] cluster assembly cell redox homeostasis metal ion binding iron-sulfur cluster binding protein maturation by iron-sulfur cluster transfer |
|
| MG-1-pos-10339502_st |
|
|
|
|
|
|
|
|
|
| TC0300001306.mm.2 |
Elovl6 |
ELOVL family member 6, elongation of long chain fatty acids (yeast) |
3 |
129532385 |
NM_130450, BC051041, BC098492, BC100576 NM_130450, BC051041, BC098492, BC100576 NM_130450, BC051041, BC098492, BC100576 NM_130450, BC051041, BC098492, BC100576 |
170439 |
55 |
endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process fatty acid elongase activity fatty acid elongase activity fatty acid elongase complex membrane integral component of membrane transferase activity transferase activity, transferring acyl groups other than amino-acyl groups fatty acid elongation, saturated fatty acid fatty acid elongation, saturated fatty acid sphingolipid biosynthetic process integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane fatty acid elongation fatty acid elongation, monounsaturated fatty acid fatty acid elongation, polyunsaturated fatty acid long-chain fatty acid biosynthetic process very long-chain fatty acid biosynthetic process 3-oxo-arachidoyl-CoA synthase activity 3-oxo-cerotoyl-CoA synthase activity 3-oxo-lignoceronyl-CoA synthase activity positive regulation of cold-induced thermogenesis |
01040 |
| TC1200001436.mm.2 |
Ddx1 |
DEAD box helicase 1 |
12 |
-13219306 |
NM_134040, BC008570, BC010624 NM_134040, BC008570, BC010624 NM_134040, BC008570, BC010624 |
104721 |
51 |
nucleotide binding immune system process positive regulation of myeloid dendritic cell cytokine production nucleic acid binding DNA binding chromatin binding transcription coregulator activity RNA binding RNA helicase activity double-stranded RNA binding helicase activity nuclease activity exonuclease activity protein binding ATP binding nucleus nucleoplasm cytoplasm mitochondrion cytosol cytosol double-strand break repair tRNA splicing, via endonucleolytic cleavage and ligation mRNA processing tRNA processing poly(A) binding response to virus cytoplasmic stress granule cytoplasmic stress granule hydrolase activity DNA duplex unwinding DNA/RNA helicase activity positive regulation of I-kappaB kinase/NF-kappaB signaling response to exogenous dsRNA innate immune response defense response to virus cleavage body tRNA-splicing ligase complex nucleic acid phosphodiester bond hydrolysis protein localization to cytoplasmic stress granule ribonucleoprotein complex |
|
| TC1200000797.mm.2 |
Acot2 |
acyl-CoA thioesterase 2 |
12 |
83987860 |
NM_134188, BC064469 NM_134188, BC064469 |
171210 |
24 |
very long-chain fatty acid metabolic process response to hypoxia long-chain fatty acid metabolic process mitochondrion mitochondrion mitochondrion lipid metabolic process fatty acid metabolic process acyl-CoA metabolic process acyl-CoA metabolic process acyl-CoA metabolic process palmitoyl-CoA hydrolase activity hydrolase activity thiolester hydrolase activity very long-chain fatty acid catabolic process acyl-CoA hydrolase activity acyl-CoA hydrolase activity acyl-CoA hydrolase activity carboxylic ester hydrolase activity myristoyl-CoA hydrolase activity |
01040 |
| TC1000003224.mm.2 |
Eif4ebp2 |
eukaryotic translation initiation factor 4E binding protein 2 |
10 |
-61432496 |
NM_010124, BC015082, BC119539 NM_010124, BC015082, BC119539 NM_010124, BC015082, BC119539 |
13688 |
78 |
protein binding cytoplasm regulation of translation regulation of translational initiation memory eukaryotic initiation factor 4E binding eukaryotic initiation factor 4E binding insulin receptor signaling pathway negative regulation of translation cAMP-mediated signaling translation repressor activity TOR signaling social behavior negative regulation of translational initiation negative regulation of translational initiation regulation of synaptic plasticity modulation of chemical synaptic transmission modulation of chemical synaptic transmission postsynapse |
|
| TC1100002813.mm.2 |
Gemin5 |
gem nuclear organelle associated protein 5 |
11 |
-58120000, -58120000 |
NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 NM_001166669, NM_001166670, NM_001166671, NM_172558, BC137802, BC144922 |
216766 |
23 |
RNA 7-methylguanosine cap binding spliceosomal snRNP assembly RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleus nucleoplasm cytoplasm cytosol mRNA processing translation regulation of translation RNA splicing nuclear body snRNA binding U1 snRNA binding U4 snRNA binding U4atac snRNA binding SMN complex SMN-Gemin2 complex SMN-Sm protein complex ribosome binding |
03013 |
| TC0100001836.mm.2 |
Nsl1 |
NSL1, MIS12 kinetochore complex component |
1 |
191063020 |
NM_198654, BC029086 NM_198654, BC029086 |
381318 |
14 |
mitotic sister chromatid segregation MIS12/MIND type complex MIS12/MIND type complex chromosome, centromeric region kinetochore condensed chromosome kinetochore molecular_function nucleus chromosome cell cycle chromosome segregation nuclear speck cell division |
|
| TC1300001631.mm.2 |
H4c6 |
H4 clustered histone 6 |
13 |
-23551285 |
NM_175655, BC156748 NM_175655, BC156748 |
319157 |
5 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein domain specific binding protein-containing complex negative regulation of megakaryocyte differentiation |
05322 |
| TC0200002442.mm.2 |
Fam83d |
family with sequence similarity 83, member D |
2 |
158768098 |
NM_027975, BC068129 NM_027975, BC068129 |
71878 |
16 |
epithelial to mesenchymal transition cytoplasm spindle cytosol cytosol cytoskeleton cell cycle signal transduction microtubule binding cell population proliferation microtubule cytoskeleton cell migration kinesin binding protein kinase binding protein kinase binding regulation of TOR signaling regulation of TOR signaling regulation of protein catabolic process intercellular bridge cell division metaphase plate congression regulation of ERK1 and ERK2 cascade regulation of ERK1 and ERK2 cascade mitotic spindle mitotic spindle pole mitotic spindle pole protein localization to mitotic spindle protein localization to mitotic spindle positive regulation of cell cycle G1/S phase transition positive regulation of cell cycle G1/S phase transition |
|
| TC1600001191.mm.2 |
Emp2 |
epithelial membrane protein 2 |
16 |
-10281748 |
NM_007929, BC041670 NM_007929, BC041670 |
13731 |
31 |
membrane raft assembly T cell mediated cytotoxicity regulation of cell-matrix adhesion regulation of cell-matrix adhesion positive regulation of cell-matrix adhesion regulation of glomerular filtration integrin binding integrin binding nucleus cytoplasm cytoplasm cytoplasm Golgi apparatus plasma membrane plasma membrane actin filament organization cell adhesion cell adhesion cell-matrix adhesion embryo implantation embryo implantation cell death positive regulation of cell population proliferation cell surface regulation of endothelial cell migration membrane integral component of membrane apical plasma membrane cell migration kinase binding protein kinase binding protein kinase binding cytoplasmic vesicle bleb assembly activation of protein kinase activity protein localization to cell surface blood vessel endothelial cell migration regulation of kinase activity early endosome to late endosome transport membrane raft membrane raft apical part of cell regulation of angiogenesis actin-mediated cell contraction protein localization to plasma membrane positive regulation of integrin-mediated signaling pathway positive regulation of integrin-mediated signaling pathway positive regulation of integrin-mediated signaling pathway regulation of vasculogenesis |
|
| TC0900001656.mm.2 |
Exosc7 |
exosome component 7 |
9 |
123113230 |
NM_001081188, BC052656, BC094932, BC132363, BC145675 NM_001081188, BC052656, BC094932, BC132363, BC145675 NM_001081188, BC052656, BC094932, BC132363, BC145675 NM_001081188, BC052656, BC094932, BC132363, BC145675 NM_001081188, BC052656, BC094932, BC132363, BC145675 |
66446 |
21 |
nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) exosome (RNase complex) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) RNA binding nucleus cytoplasm rRNA processing rRNA catabolic process nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' U1 snRNA 3'-end processing U4 snRNA 3'-end processing U5 snRNA 3'-end processing exonucleolytic catabolism of deadenylated mRNA nuclear mRNA surveillance nuclear polyadenylation-dependent rRNA catabolic process nuclear polyadenylation-dependent tRNA catabolic process nuclear polyadenylation-dependent mRNA catabolic process |
03018 |
| TC1100002549.mm.2 |
Hmmr |
hyaluronan mediated motility receptor (RHAMM) |
11 |
-40701387 |
NM_013552, BC021427 NM_013552, BC021427 |
15366 |
47 |
hyaluronic acid binding cytoplasm centrosome cytosol microtubule cytoskeleton |
04512 |
| TC1900001514.mm.2 |
Exosc1 |
exosome component 1 |
19 |
-41922979 |
NM_001164561, NM_025644, BC024423 NM_001164561, NM_025644, BC024423 NM_001164561, NM_025644, BC024423 |
66583 |
25 |
nuclear exosome (RNase complex) exosome (RNase complex) RNA binding protein binding nucleus nucleolus cytoplasm rRNA processing RNA processing |
03018 |
| TC0800001263.mm.2 |
Nip7 |
NIP7, nucleolar pre-rRNA processing protein |
8 |
107056876 |
NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972 NM_001164472, NM_025391, NR_028367, BC003972 |
66164 |
19 |
RNA binding nucleus nucleoplasm nucleolus nucleolus cytosol preribosome, large subunit precursor ribosome biogenesis ribosome assembly ribosomal large subunit biogenesis |
|
| TC0900001210.mm.2 |
Tfdp2 |
transcription factor Dp 2 |
9 |
96259247, 96196274, 96258704 |
NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 NM_001184706, NM_001184708, NM_001184709, NM_001184710, NM_001184711, NM_178667, BC141080 |
211586 |
37 |
mitotic cell cycle RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity transcription coregulator activity protein binding nucleus nuclear envelope nucleoplasm nucleoplasm transcription regulator complex regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell cycle transcription factor binding protein domain specific binding negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II regulation of cell cycle mitotic spindle RNA polymerase II transcription regulator complex |
04110 |
| TC0100001178.mm.2 |
Nucks1 |
nuclear casein kinase and cyclin-dependent kinase substrate 1 |
1 |
131910457 |
NM_001145804, NM_175294, BC039951 NM_001145804, NM_175294, BC039951 NM_001145804, NM_175294, BC039951 |
98415 |
32 |
double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromatin chromatin cellular glucose homeostasis chromatin binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding transcription coactivator activity nucleus nucleus nucleoplasm chromosome nucleolus cytoplasm cytoplasm cytoplasm regulation of DNA replication DNA repair chromatin organization regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus transcription factor binding release from viral latency replication fork processing interstrand cross-link repair interstrand cross-link repair glucose homeostasis positive regulation by host of viral transcription positive regulation by host of viral genome replication positive regulation of transcription by RNA polymerase II regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway regulation of DNA strand elongation cellular response to X-ray modulation by host of RNA binding by virus modulation by host of viral RNA-binding transcription factor activity |
|
| TC1500001005.mm.2 |
Troap |
trophinin associated protein |
15 |
99074972 |
NM_001162506, NM_030159, BC145227 NM_001162506, NM_030159, BC145227 NM_001162506, NM_030159, BC145227 |
78733 |
12 |
molecular_function cellular_component cytoplasm cell adhesion biological_process |
|
| TC1900000212.mm.2 |
Prpf19 |
pre-mRNA processing factor 19 |
19 |
10898644, 10895230 |
NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070 NM_001253843, NM_001253844, NM_134129, BC004070 |
28000 |
38 |
protein polyubiquitination spliceosomal tri-snRNP complex assembly spliceosomal complex assembly generation of catalytic spliceosome for first transesterification step mRNA splicing, via spliceosome Prp19 complex Prp19 complex inner cell mass cell proliferation ubiquitin-protein transferase activity protein binding nucleus nucleus DNA replication factor A complex spliceosomal complex cytoplasm cytoplasm lipid droplet cytoskeleton DNA repair double-strand break repair via nonhomologous end joining mRNA processing cellular response to DNA damage stimulus RNA splicing lipid biosynthetic process proteasomal protein catabolic process proteasomal protein catabolic process nuclear speck transferase activity ubiquitin-ubiquitin ligase activity cellular protein localization site of double-strand break identical protein binding negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of mRNA splicing, via spliceosome positive regulation of astrocyte differentiation positive regulation of astrocyte differentiation ubiquitin protein ligase activity protein K63-linked ubiquitination U2-type catalytic step 1 spliceosome U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome signal transduction involved in DNA damage checkpoint |
03040 04120 |
| TC0500000054.mm.2 |
Abcb4 |
ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
5 |
8893720 |
NM_008830, BC150687 NM_008830, BC150687 |
18670 |
156 |
Golgi membrane nucleotide binding ATP binding nucleoplasm cytoplasm cytosol plasma membrane plasma membrane plasma membrane plasma membrane focal adhesion lipid transport actin cytoskeleton membrane integral component of membrane apical plasma membrane ATPase activity cytoplasmic vesicle positive regulation of cholesterol transport bile acid secretion ATPase-coupled transmembrane transporter activity ATPase-coupled transmembrane transporter activity xenobiotic transmembrane transporter activity phospholipid translocation phospholipid translocation intercellular canaliculus transmembrane transport lipid homeostasis positive regulation of phospholipid translocation phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylethanolamine flippase activity ceramide floppase activity response to fenofibrate cellular response to bile acid positive regulation of phospholipid transport |
02010 04976 |
| TC0400003849.mm.2 |
Mrto4 |
mRNA turnover 4, ribosome maturation factor |
4 |
-139347439 |
NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205 NM_023536, BC005734, BC138221, BC145205 |
69902 |
26 |
ribosomal large subunit assembly nuclear-transcribed mRNA catabolic process intracellular anatomical structure nucleus nucleolus cytoplasm rRNA processing preribosome, large subunit precursor ribosome biogenesis ribosomal large subunit biogenesis |
|
| TC0700000798.mm.2 |
|
|
|
|
NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896 NM_025880, NR_028533, BC016099, BC059896 |
|
|
molecular_function cellular_component biological_process |
|
| MG-1-pos-10341561_st |
|
|
|
|
|
|
|
|
|
| TC1700001888.mm.2 |
Rps18 |
ribosomal protein S18 |
17 |
-33951997 |
NM_011296, BC081458, BC081459, BC093500, BC100604 NM_011296, BC081458, BC081459, BC093500, BC100604 NM_011296, BC081458, BC081459, BC093500, BC100604 NM_011296, BC081458, BC081459, BC093500, BC100604 NM_011296, BC081458, BC081459, BC093500, BC100604 |
20084 |
42 |
nucleic acid binding RNA binding structural constituent of ribosome protein binding intracellular anatomical structure nucleus cytoplasm cytosol cytosol ribosome translation postsynaptic density small ribosomal subunit rRNA binding protein kinase binding cytosolic small ribosomal subunit synapse synapse |
03010 |
| TC0X00001323.mm.2 |
Bex3 |
brain expressed X-linked 3 |
X |
136270252 |
NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815 NM_001110233, NM_001110234, NM_009750, BC027815 |
12070 |
35 |
signaling receptor binding death receptor binding nucleus cytoplasm cytoplasm cytosol cytosol cytosol apoptotic process signal transduction extrinsic apoptotic signaling pathway via death domain receptors identical protein binding metal ion binding |
04722 |
| TC0800000987.mm.2 |
Orc6 |
origin recognition complex, subunit 6 |
8 |
85299631 |
NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739 NM_001163791, NM_019716, NR_028268, BC080739 |
56452 |
21 |
origin recognition complex fibrillar center DNA binding nucleus nucleoplasm nuclear origin of replication recognition complex DNA replication DNA-dependent DNA replication DNA replication initiation negative regulation of cell division |
04110 |
| TC1400002600.mm.2 |
Dis3 |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease |
14 |
-99076633 |
NM_028315, BC027357 NM_028315, BC027357 |
72662 |
27 |
3'-5'-exoribonuclease activity 3'-5'-exoribonuclease activity nuclear exosome (RNase complex) nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) exosome (RNase complex) RNA binding nuclease activity endonuclease activity endonuclease activity exonuclease activity ribonuclease activity guanyl-nucleotide exchange factor activity nucleus nucleoplasm cytoplasm cytosol rRNA processing rRNA catabolic process rRNA catabolic process hydrolase activity CUT catabolic process |
03018 |
| TC0700003988.mm.2 |
Rrp8 |
ribosomal RNA processing 8 |
7 |
-105731729, -105731729 |
NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799 NM_025897, NM_133951, BC022923, BC046799 |
101867 |
23 |
rDNA heterochromatin assembly rDNA heterochromatin assembly nucleus nucleoplasm chromatin silencing complex chromatin silencing complex nucleolus nucleolus cytosol plasma membrane chromatin organization rRNA processing methyltransferase activity transferase activity methylation rDNA heterochromatin rDNA heterochromatin methylated histone binding methylated histone binding cellular response to glucose starvation cellular response to glucose starvation regulation of transcription by glucose regulation of transcription by glucose positive regulation of cell cycle arrest intrinsic apoptotic signaling pathway by p53 class mediator |
|
| TC0200004953.mm.2 |
|
|
|
|
NM_016661, BC015304, BC086781, BC108367 NM_016661, BC015304, BC086781, BC108367 NM_016661, BC015304, BC086781, BC108367 NM_016661, BC015304, BC086781, BC108367 |
|
|
chronic inflammatory response to antigenic stimulus adenosylhomocysteinase activity adenosylhomocysteinase activity adenosylhomocysteinase activity copper ion binding protein binding nucleus cytosol cytosol cytosol response to nutrient S-adenosylhomocysteine catabolic process S-adenosylhomocysteine catabolic process adenyl nucleotide binding S-adenosylmethionine cycle circadian sleep/wake cycle identical protein binding neuron projection protein self-association NAD binding |
|
| TC1000001579.mm.2 |
Prim1 |
DNA primase, p49 subunit |
10 |
128015214 |
NM_008921, BC089544 NM_008921, BC089544 |
19075 |
29 |
DNA primase activity DNA primase activity DNA-directed 5'-3' RNA polymerase activity protein binding alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex DNA replication DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer transferase activity nucleotidyltransferase activity metal ion binding primosome complex |
00230 00240 01100 03030 |
| TC0X00002556.mm.2 |
Gk |
glycerol kinase |
X |
-85701936 |
NM_008194, NM_212444, BC003767 NM_008194, NM_212444, BC003767 NM_008194, NM_212444, BC003767 |
14933 |
47 |
nucleotide binding glycerol kinase activity glycerol kinase activity glycerol kinase activity ATP binding nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial outer membrane cytosol carbohydrate metabolic process glycerol metabolic process glycerol metabolic process glycerol-3-phosphate metabolic process triglyceride metabolic process membrane kinase activity phosphorylation transferase activity phosphotransferase activity, alcohol group as acceptor regulation of fatty acid metabolic process histone binding glucose homeostasis response to ethanol glycerol-3-phosphate biosynthetic process |
00561 01100 03320 |
| TC1100001010.mm.2 |
Atp2a3 |
ATPase, Ca++ transporting, ubiquitous |
11 |
72961168 |
NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 NM_001163336, NM_001163337, NM_016745, BC017639, BC026147 |
53313 |
37 |
nucleotide binding calcium transmembrane transporter activity, phosphorylative mechanism calcium transmembrane transporter activity, phosphorylative mechanism calcium ion binding protein binding ATP binding endoplasmic reticulum endoplasmic reticulum ion transport calcium ion transport cellular calcium ion homeostasis cellular calcium ion homeostasis activation of cysteine-type endopeptidase activity involved in apoptotic process proton-exporting ATPase activity, phosphorylative mechanism cysteine-type endopeptidase activator activity involved in apoptotic process calcium ion transmembrane transporter activity membrane integral component of membrane sarcoplasmic reticulum ATPase activity calcium-dependent ATPase activity organelle membrane endoplasmic reticulum calcium ion homeostasis sarcoplasmic reticulum membrane ion channel binding metal ion binding intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress calcium ion transmembrane transport calcium ion transmembrane transport negative regulation of receptor binding calcium ion transport from cytosol to endoplasmic reticulum |
04020 04972 05010 |
| TC1600000088.mm.2 |
Mettl22 |
methyltransferase like 22 |
16 |
8470812 |
NM_146247, BC024814 NM_146247, BC024814 |
239706 |
16 |
nucleus nucleus nucleoplasm nucleolus protein methylation methyltransferase activity protein methyltransferase activity protein methyltransferase activity transferase activity heat shock protein binding methylation protein-containing complex |
|
| TC1100000028.mm.2 |
Pes1 |
pescadillo ribosomal biogenesis factor 1 |
11 |
3963974 |
NM_022889, BC004844, BC011142 NM_022889, BC004844, BC011142 NM_022889, BC004844, BC011142 |
64934 |
35 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) condensed chromosome RNA binding protein binding nucleus nucleoplasm chromosome nucleolus nucleolus cytosol rRNA processing rRNA processing rRNA processing nucleolus organization cell population proliferation preribosome, large subunit precursor protein localization to organelle ribosome biogenesis regulation of cell cycle PeBoW complex PeBoW complex PeBoW complex |
|
| TC1400001935.mm.2 |
Dlgap5 |
DLG associated protein 5 |
14 |
-47387778 |
NM_144553, BC058087, NM_001145949 NM_144553, BC058087, NM_001145949 NM_144553, BC058087, NM_001145949 |
218977 |
24 |
nucleus nucleus cytoplasm mitochondrion cytosol cytoskeleton cell cycle mitotic spindle organization chromosome segregation regulation of mitotic cell cycle microtubule binding signaling spindle pole centrosome spindle pole centrosome centriolar satellite kinetochore assembly centrosome localization |
|
| TC0400002275.mm.2 |
Atp6v0d2 |
ATPase, H+ transporting, lysosomal V0 subunit D2 |
4 |
-19876837 |
NM_175406, BC087899 NM_175406, BC087899 |
242341 |
45 |
lysosomal membrane endosome early endosome early endosome ion transport vacuolar transport vacuolar acidification proton transmembrane transporter activity membrane apical plasma membrane vacuolar proton-transporting V-type ATPase complex vacuolar proton-transporting V-type ATPase complex proton-transporting V-type ATPase, V0 domain plasma membrane proton-transporting V-type ATPase complex proton-transporting ATPase activity, rotational mechanism proton transmembrane transport |
00190 01100 04142 04145 04966 05323 |
| MG-1-pos-10340389_st |
|
|
|
|
|
|
|
|
|
| TC0500001732.mm.2 |
Kdelr2 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
5 |
143403819 |
NM_025841, BC007146 NM_025841, BC007146 |
66913 |
17 |
Golgi membrane KDEL sequence binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus cis-Golgi network cis-Golgi network protein retention in ER lumen endoplasmic reticulum to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum protein transport membrane integral component of membrane vesicle-mediated transport COPI-coated vesicle membrane cytoplasmic vesicle ER retention sequence binding |
|
| TC0200005271.mm.2 |
Aurka |
aurora kinase A |
2 |
-172356189 |
NM_011497, BC005425, BC014711 NM_011497, BC005425, BC014711 NM_011497, BC005425, BC014711 |
20878 |
115 |
nucleotide binding meiotic spindle organization microtubule cytoskeleton organization mitotic cell cycle protein kinase activity protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleoplasm nucleoplasm cytoplasm centrosome centrosome microtubule organizing center spindle cytosol cytosol cytoskeleton microtubule spindle microtubule spindle microtubule cilium protein phosphorylation protein phosphorylation cell cycle spindle organization mitotic spindle organization mitotic spindle organization spindle assembly involved in female meiosis I centrosome cycle mitotic centrosome separation mitotic centrosome separation response to wounding anterior/posterior axis specification negative regulation of gene expression microtubule cytoskeleton kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation protein kinase binding cell projection organization spindle pole centrosome spindle pole centrosome ubiquitin protein ligase binding regulation of protein stability negative regulation of protein binding chromosome passenger complex positive regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of cytokinesis histone serine kinase activity histone serine kinase activity germinal vesicle cell projection negative regulation of apoptotic process axon hillock pronucleus protein heterodimerization activity perinuclear region of cytoplasm spindle midzone cell division meiotic cell cycle centrosome localization protein localization to centrosome mitotic spindle meiotic spindle negative regulation of spindle checkpoint liver regeneration mitotic spindle pole positive regulation of oocyte maturation neuron projection extension |
04114 |
| TC0X00000471.mm.2 |
Hprt |
hypoxanthine guanine phosphoribosyl transferase |
X |
52988077 |
NM_013556, BC004686, BC083145 NM_013556, BC004686, BC083145 NM_013556, BC004686, BC083145 |
15452 |
521 |
nucleotide binding magnesium ion binding magnesium ion binding T cell mediated cytotoxicity response to amphetamine hypoxanthine phosphoribosyltransferase activity hypoxanthine phosphoribosyltransferase activity hypoxanthine phosphoribosyltransferase activity hypoxanthine phosphoribosyltransferase activity cytoplasm cytoplasm cytosol purine nucleotide biosynthetic process purine ribonucleoside salvage purine ribonucleoside salvage purine ribonucleoside salvage adenine salvage adenine salvage guanine salvage guanine salvage guanine salvage grooming behavior locomotory behavior nucleoside metabolic process transferase activity transferase activity, transferring glycosyl groups striatum development cerebral cortex neuron differentiation central nervous system neuron development GMP salvage IMP salvage dopamine metabolic process identical protein binding identical protein binding hypoxanthine salvage positive regulation of dopamine metabolic process GMP catabolic process IMP metabolic process adenine metabolic process adenine metabolic process hypoxanthine metabolic process hypoxanthine metabolic process hypoxanthine metabolic process hypoxanthine metabolic process lymphocyte proliferation metal ion binding dendrite morphogenesis protein homotetramerization guanine phosphoribosyltransferase activity |
00230 00983 01100 |
| TC1200002246.mm.2 |
Atxn3 |
ataxin 3 |
12 |
-101918900, -101932923 |
NM_001167914, NM_029705, BC087880 NM_001167914, NM_029705, BC087880 NM_001167914, NM_029705, BC087880 |
110616 |
80 |
microtubule cytoskeleton organization RNA polymerase II transcription regulatory region sequence-specific DNA binding histone deacetylase activity thiol-dependent ubiquitin-specific protease activity thiol-dependent ubiquitin-specific protease activity protein binding nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm mitochondrial matrix endoplasmic reticulum membrane cytosol plasma membrane ubiquitin-dependent protein catabolic process protein quality control for misfolded or incompletely synthesized proteins peptidase activity cysteine-type peptidase activity regulation of cell-substrate adhesion regulation of cell-substrate adhesion protein deubiquitination protein deubiquitination hydrolase activity actin cytoskeleton organization ubiquitin protein ligase binding ubiquitin protein ligase binding mitochondrial membrane cellular response to heat monoubiquitinated protein deubiquitination exploration behavior nuclear inclusion body identical protein binding proteasome-mediated ubiquitin-dependent protein catabolic process intermediate filament cytoskeleton organization ATPase binding Lys63-specific deubiquitinase activity protein K63-linked deubiquitination protein K48-linked deubiquitination cellular response to misfolded protein positive regulation of ERAD pathway protein localization to cytosolic proteasome complex involved in ERAD pathway Lys48-specific deubiquitinase activity |
04141 |
| TC1600001308.mm.2 |
Ranbp1 |
RAN binding protein 1 |
16 |
-18239978 |
NM_011239, BC061140 NM_011239, BC061140 |
19385 |
59 |
GDP-dissociation inhibitor activity GTPase activator activity nucleus nuclear pore cytoplasm cytoplasm cytoplasm centrosome centrosome cytosol spindle organization positive regulation of neuron projection development plasma membrane bounded cell projection cytoplasm positive regulation of mitotic centrosome separation positive regulation of mitotic centrosome separation intracellular transport cellular response to leptomycin B axon cytoplasm |
|
| TC0300001488.mm.2 |
Mcoln3 |
mucolipin 3 |
3 |
146121790 |
NM_134160, BC106856, BC106857 NM_134160, BC106856, BC106857 NM_134160, BC106856, BC106857 |
171166 |
53 |
cation channel activity cytoplasm lysosomal membrane endosome plasma membrane plasma membrane ion transport sensory perception of sound locomotory behavior lipid binding membrane integral component of membrane cytoplasmic vesicle inner ear auditory receptor cell differentiation cell projection NAADP-sensitive calcium-release channel activity |
|
| TC0700004321.mm.2 |
Sephs2 |
selenophosphate synthetase 2 |
7 |
-127271878 |
NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334 NM_009266, BC016508, BC028966, BC043334 |
20768 |
20 |
nucleotide binding selenium compound metabolic process selenium compound metabolic process selenide, water dikinase activity selenide, water dikinase activity ATP binding cytoplasm selenocysteine biosynthetic process selenocysteine biosynthetic process kinase activity phosphorylation transferase activity metal ion binding |
00450 01100 |
| TC0700002924.mm.2 |
|
|
|
|
XR_105097 |
|
|
|
|
| TC0900001302.mm.2 |
Topbp1 |
topoisomerase (DNA) II binding protein 1 |
9 |
103305326 |
NM_176979, BC049797 NM_176979, BC049797 |
235559 |
50 |
condensed nuclear chromosome male germ cell nucleus DNA binding nucleus nucleoplasm chromosome chromosome cytoplasm cytoskeleton plasma membrane DNA replication initiation DNA repair cellular response to DNA damage stimulus mitotic G2 DNA damage checkpoint reciprocal meiotic recombination response to ionizing radiation actin cytoskeleton nuclear body PML body mitotic DNA replication checkpoint identical protein binding intracellular membrane-bounded organelle |
|
| TC0700002426.mm.2 |
Sae1 |
SUMO1 activating enzyme subunit 1 |
7 |
-16320235, -16327050 |
NM_001285891, NM_001285892, NM_019748, BC068164 NM_001285891, NM_001285892, NM_019748, BC068164 NM_001285891, NM_001285892, NM_019748, BC068164 NM_001285891, NM_001285892, NM_019748, BC068164 |
56459 |
27 |
nucleus nucleoplasm cytoplasm cellular protein modification process protein C-terminus binding ubiquitin-like modifier activating enzyme activity ligase activity protein sumoylation protein sumoylation SUMO activating enzyme activity SUMO activating enzyme activity SUMO activating enzyme complex SUMO activating enzyme complex protein modification by small protein conjugation positive regulation of protein sumoylation ATP-dependent protein binding small protein activating enzyme binding protein heterodimerization activity |
04120 |
| TC0800000648.mm.2 |
Hpf1 |
histone PARylation factor 1 |
8 |
60890427 |
NM_028299, BC042740 NM_028299, BC042740 |
72612 |
16 |
nucleus nucleus cellular response to DNA damage stimulus cellular response to DNA damage stimulus zinc ion binding regulation of protein ADP-ribosylation regulation of protein ADP-ribosylation peptidyl-serine ADP-ribosylation peptidyl-serine ADP-ribosylation histone binding histone binding poly-ADP-D-ribose binding |
|
| TC0300001046.mm.2 |
Dennd2c |
DENN/MADD domain containing 2C |
3 |
103140325, 103127555, 103102658 |
NM_177857, BC060666 NM_177857, BC060666 |
329727 |
21 |
guanyl-nucleotide exchange factor activity nucleoplasm |
|
| TC0100000351.mm.2 |
Wdr75 |
WD repeat domain 75 |
1 |
45795165 |
NM_028599, BC117880, BC117881 NM_028599, BC117880, BC117881 NM_028599, BC117880, BC117881 |
73674 |
23 |
nucleus nucleolus rRNA processing ribosome biogenesis positive regulation of transcription by RNA polymerase I positive regulation of rRNA processing |
03008 |
| TC0700001348.mm.2 |
Alg8 |
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase) |
7 |
97371616 |
NM_199035, BC061244 NM_199035, BC061244 |
381903 |
20 |
alpha-1,3-mannosyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane protein N-linked glycosylation protein N-linked glycosylation oligosaccharide-lipid intermediate biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups protein N-linked glycosylation via asparagine dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity |
00510 01100 |
| TC0600002548.mm.2 |
Pole4 |
polymerase (DNA-directed), epsilon 4 (p12 subunit) |
6 |
-82646711, -82618354 |
NM_025882, BC023189 NM_025882, BC023189 |
66979 |
31 |
DNA binding nucleus Ada2/Gcn5/Ada3 transcription activator complex epsilon DNA polymerase complex epsilon DNA polymerase complex protein heterodimerization activity |
00230 00240 01100 03030 03410 03420 |
| TC0600002658.mm.2 |
Aplf |
aprataxin and PNKP like factor |
6 |
-87628428, -87628424 |
NM_001170489, NM_024251, BC002179 NM_001170489, NM_024251, BC002179 NM_001170489, NM_024251, BC002179 |
72103 |
19 |
single strand break repair nucleotide binding DNA-(apurinic or apyrimidinic site) endonuclease activity DNA-(apurinic or apyrimidinic site) endonuclease activity endodeoxyribonuclease activity nucleus nucleus nucleoplasm chromosome cytoplasm DNA repair double-strand break repair double-strand break repair double-strand break repair cellular response to DNA damage stimulus 3'-5' exonuclease activity hydrolase activity site of double-strand break site of double-strand break regulation of isotype switching metal ion binding positive regulation of DNA ligation |
|
| TC1000002517.mm.2 |
Lsm7 |
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated |
10 |
-80852824, -80852824 |
NM_025349, BC027511, BC081444 NM_025349, BC027511, BC081444 NM_025349, BC027511, BC081444 |
66094 |
15 |
mRNA splicing, via spliceosome nuclear-transcribed mRNA catabolic process RNA binding protein binding nucleus spliceosomal complex U6 snRNP U12-type spliceosomal complex cytoplasm mRNA processing mRNA catabolic process RNA splicing U4/U6 x U5 tri-snRNP complex protein heterodimerization activity U2-type prespliceosome U2-type precatalytic spliceosome catalytic step 2 spliceosome spliceosomal tri-snRNP complex Lsm2-8 complex Lsm1-7-Pat1 complex ribonucleoprotein complex |
|
| TC0900001056.mm.2 |
Cd109 |
CD109 antigen |
9 |
78615545 |
NM_153098, BC052443, CD109 NM_153098, BC052443, CD109 NM_153098, BC052443, CD109 |
235505 |
36 |
negative regulation of protein phosphorylation hair follicle development endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity extracellular region extracellular space cytosol plasma membrane negative regulation of peptidase activity negative regulation of keratinocyte proliferation membrane peptidase inhibitor activity negative regulation of transforming growth factor beta receptor signaling pathway anchored component of membrane regulation of keratinocyte differentiation transforming growth factor beta binding negative regulation of wound healing osteoclast fusion |
|
| TC1400002649.mm.2 |
Obi1 |
ORC ubiquitin ligase 1 |
14 |
-104477533 |
NM_026047, BC029231 NM_026047, BC029231 |
72486 |
21 |
chromatin chromatin binding ubiquitin-protein transferase activity chromosome regulation of DNA replication protein monoubiquitination transferase activity metal ion binding positive regulation of mRNA splicing, via spliceosome protein autoubiquitination |
|
| TC0500003271.mm.2 |
Scarb1 |
scavenger receptor class B, member 1 |
5 |
-125277086, -125283319 |
NM_001205082, NM_001205083, NM_016741, BC004656 NM_001205082, NM_001205083, NM_016741, BC004656 NM_001205082, NM_001205083, NM_016741, BC004656 NM_001205082, NM_001205083, NM_016741, BC004656 |
20778 |
368 |
lipopolysaccharide binding amyloid-beta binding phosphatidylserine binding lipopolysaccharide immune receptor activity endothelial cell proliferation scavenger receptor activity cytoplasm cytoplasm cytoplasm lysosome plasma membrane plasma membrane plasma membrane integral component of plasma membrane caveola caveola androgen biosynthetic process cholesterol catabolic process cholesterol catabolic process lipid transport phagocytosis, recognition high-density lipoprotein particle binding lipid binding cell surface cell surface positive regulation of triglyceride biosynthetic process positive regulation of cholesterol storage positive regulation of cholesterol storage regulation of phosphatidylcholine catabolic process phospholipid transport lipopolysaccharide transport membrane integral component of membrane low-density lipoprotein particle binding low-density lipoprotein particle binding low-density lipoprotein particle binding cholesterol transport cholesterol transport microvillus membrane detection of lipopolysaccharide cholesterol efflux cholesterol efflux cholesterol efflux cholesterol efflux apolipoprotein binding apolipoprotein binding apolipoprotein A-I binding high-density lipoprotein particle remodeling plasma lipoprotein particle clearance low-density lipoprotein particle clearance high-density lipoprotein particle clearance high-density lipoprotein particle clearance vitamin transmembrane transport cholesterol homeostasis identical protein binding intracellular membrane-bounded organelle blood vessel endothelial cell migration recognition of apoptotic cell recognition of apoptotic cell recognition of apoptotic cell reverse cholesterol transport adhesion of symbiont to host regulation of phagocytosis intestinal absorption positive regulation of nitric-oxide synthase activity triglyceride homeostasis high-density lipoprotein particle receptor activity high-density lipoprotein particle receptor activity cholesterol import cholesterol import cholesterol import cholesterol import |
04145 04975 04976 04977 05160 |
| TC0600000985.mm.2 |
Fam136a |
family with sequence similarity 136, member A |
6 |
86365645, 86365470 |
NM_025591, BC024049, BC103775 NM_025591, BC024049, BC103775 NM_025591, BC024049, BC103775 |
66488 |
17 |
molecular_function cytoplasm cytoplasm mitochondrion biological_process |
|
| TC0500002231.mm.2 |
Mxd4 |
Max dimerization protein 4 |
5 |
-34176579 |
NM_010753, BC011303 NM_010753, BC011303 |
17122 |
31 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding protein binding nucleus regulation of transcription by RNA polymerase II negative regulation of transcription, DNA-templated protein dimerization activity RNA polymerase II transcription regulator complex |
|
| TC1300000383.mm.2 |
Nqo2 |
N-ribosyldihydronicotinamide quinone reductase 2 |
13 |
33967152, 33964658 |
NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 NM_001163239, NM_001163241, NM_001163242, NM_020282, BC027629 |
18105 |
32 |
dihydronicotinamide riboside quinone reductase activity NAD(P)H dehydrogenase (quinone) activity nucleoplasm cytoplasm cytosol cytosol zinc ion binding electron transfer activity oxidoreductase activity oxidoreductase activity, acting on other nitrogenous compounds as donors chloride ion binding protein homodimerization activity positive regulation of neuron apoptotic process metal ion binding positive regulation of ERK1 and ERK2 cascade FAD binding melatonin binding positive regulation of vascular associated smooth muscle cell proliferation resveratrol binding positive regulation of reactive oxygen species metabolic process |
|
| TC0700002057.mm.2 |
Ap2a2 |
adaptor-related protein complex 2, alpha 2 subunit |
7 |
141562179 |
NM_007459, BC058099 NM_007459, BC058099 |
11772 |
78 |
protein binding plasma membrane clathrin-coated pit intracellular protein transport endocytosis receptor-mediated endocytosis synaptic vesicle lipid binding protein transport membrane vesicle-mediated transport kinase binding protein kinase binding protein domain specific binding membrane coat AP-2 adaptor complex AP-2 adaptor complex AP-2 adaptor complex clathrin adaptor complex secretory granule cytoplasmic vesicle phosphatidylinositol binding clathrin adaptor activity protein-containing complex binding clathrin-dependent endocytosis clathrin-dependent endocytosis clathrin-dependent endocytosis disordered domain specific binding cargo adaptor activity regulation of hematopoietic stem cell differentiation |
04144 05016 |
| TC0800000912.mm.2 |
Rnf150 |
ring finger protein 150 |
8 |
82863355 |
NM_177378, BC160221 NM_177378, BC160221 |
330812 |
10 |
cytoplasm ubiquitin-dependent protein catabolic process membrane integral component of membrane metal ion binding ubiquitin protein ligase activity |
|
| TC0500001648.mm.2 |
Nxpe5 |
neurexophilin and PC-esterase domain family, member 5 |
5 |
138225903 |
NM_001013773, BC055004, BC106195 NM_001013773, BC055004, BC106195 NM_001013773, BC055004, BC106195 |
381680 |
10 |
molecular_function cellular_component biological_process |
|
| TC1100002029.mm.2 |
Mrpl12 |
mitochondrial ribosomal protein L12 |
11 |
120484636 |
NM_027204, BC005712, BC019565 NM_027204, BC005712, BC019565 NM_027204, BC005712, BC019565 |
56282 |
26 |
structural constituent of ribosome intracellular anatomical structure mitochondrion mitochondrion mitochondrial ribosome mitochondrial large ribosomal subunit mitochondrial large ribosomal subunit ribosome mitochondrial transcription mitochondrial transcription translation positive regulation of transcription, DNA-templated |
|
| TC1800001230.mm.2 |
Gnpda1 |
glucosamine-6-phosphate deaminase 1 |
18 |
-38327536 |
NM_011937, BC014800 NM_011937, BC014800 |
26384 |
25 |
glucosamine-6-phosphate deaminase activity glucosamine-6-phosphate deaminase activity glucosamine-6-phosphate deaminase activity cytoplasm cytoplasm carbohydrate metabolic process fructose 6-phosphate metabolic process glucosamine metabolic process glucosamine catabolic process glucosamine catabolic process N-acetylglucosamine metabolic process N-acetylglucosamine catabolic process UDP-N-acetylglucosamine biosynthetic process generation of precursor metabolites and energy acrosome reaction hydrolase activity N-acetylneuraminate catabolic process identical protein binding fructose biosynthetic process |
00520 01100 |
| TC1700001357.mm.2 |
Tfb1m |
transcription factor B1, mitochondrial |
17 |
-3519250 |
NM_146074, BC032930 NM_146074, BC032930 |
224481 |
26 |
rRNA modification rRNA (adenine-N6,N6-)-dimethyltransferase activity rRNA (adenine-N6,N6-)-dimethyltransferase activity DNA binding RNA binding mitochondrion mitochondrial matrix rRNA processing transcription initiation from mitochondrial promoter methyltransferase activity rRNA methyltransferase activity transferase activity rRNA methylation methylation mitochondrial transcription factor activity mitochondrial nucleoid |
|
| TC0200004808.mm.2 |
Thbd |
thrombomodulin |
2 |
-148404470 |
NM_009378, BC019154 NM_009378, BC019154 |
21824 |
120 |
transmembrane signaling receptor activity calcium ion binding extracellular space vacuolar membrane plasma membrane plasma membrane integral component of plasma membrane female pregnancy blood coagulation hemostasis embryo development external side of plasma membrane cell surface membrane integral component of membrane apicolateral plasma membrane negative regulation of blood coagulation negative regulation of coagulation |
04610 |
| TC0200001056.mm.2 |
Cdca7 |
cell division cycle associated 7 |
2 |
72476218 |
NM_025866, BC066169 NM_025866, BC066169 |
66953 |
36 |
molecular_function nucleus nucleus nucleoplasm cytoplasm cytosol regulation of transcription, DNA-templated apoptotic process regulation of cell population proliferation |
|
| TC1200001030.mm.2 |
Ifi27 |
interferon, alpha-inducible protein 27 |
12 |
103434188 |
NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 NM_026790, NM_194066, NM_194067, NM_194068, NM_194069, BC125301, BC125636, BC128276 |
52668 |
21 |
negative regulation of transcription by RNA polymerase II RNA polymerase II activating transcription factor binding lamin binding nuclear inner membrane mitochondrion regulation of protein export from nucleus apoptotic signaling pathway |
|
| TC1300001509.mm.2 |
Yae1d1 |
Yae1 domain containing 1 |
13 |
-17986639 |
NM_025904, BC048453, BC083111 NM_025904, BC048453, BC083111 NM_025904, BC048453, BC083111 |
67008 |
15 |
molecular_function cellular_component protein maturation by [4Fe-4S] cluster transfer |
|
| TC1000001203.mm.2 |
Poc1b |
POC1 centriolar protein B |
10 |
99107081 |
NM_027740, BC145801 NM_027740, BC145801 |
382406 |
15 |
spindle pole retina homeostasis molecular_function cytoplasm centrosome centriole cytoskeleton centriole replication cell population proliferation cell projection organization ciliary basal body cell projection cilium assembly |
|
| TC1500001653.mm.2 |
Tmem71 |
transmembrane protein 71 |
15 |
-66526211 |
NM_172514, BC117823, BC117824 NM_172514, BC117823, BC117824 NM_172514, BC117823, BC117824 |
213068 |
13 |
molecular_function mitochondrion biological_process membrane integral component of membrane |
|
| TC0200004376.mm.2 |
Dph6 |
diphthamine biosynthesis 6 |
2 |
-114516417 |
NM_025675, BC022995 NM_025675, BC022995 |
66632 |
17 |
nucleotide binding ATP binding nucleoplasm nucleolus ligase activity diphthine-ammonia ligase activity diphthine-ammonia ligase activity peptidyl-diphthamide biosynthetic process from peptidyl-histidine |
|
| TC1200000596.mm.2 |
Frmd6 |
FERM domain containing 6 |
12 |
70825513 |
NM_028127, BC053929 NM_028127, BC053929 |
319710 |
24 |
apical constriction protein binding cytoplasm cytoskeleton plasma membrane membrane actomyosin structure organization regulation of actin filament-based process cellular protein localization apical junction complex |
|
| TC1300001419.mm.2 |
Gtpbp4 |
GTP binding protein 4 |
13 |
-8972477 |
NM_027000, BC025431 NM_027000, BC025431 |
69237 |
30 |
regulation of cyclin-dependent protein serine/threonine kinase activity nucleotide binding maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleus nucleoplasm nucleolus cytoplasm cytosol negative regulation of DNA replication negative regulation of cell population proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination nuclear membrane negative regulation of collagen binding ribosome biogenesis perinuclear region of cytoplasm protein stabilization |
03008 |
| TC1900001313.mm.2 |
Pum3 |
pumilio RNA-binding family member 3 |
19 |
-27388697 |
NM_177474 |
52874 |
26 |
DNA binding RNA binding mRNA binding nucleus nucleoplasm chromosome nucleolus nucleolus endoplasmic reticulum regulation of translation regulation of protein ADP-ribosylation |
|
| TC0400004151.mm.2 |
Atad3a |
ATPase family, AAA domain containing 3A |
4 |
-155740639 |
NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036 NM_179203, BC023301, BC058373, BC060036 |
108888 |
43 |
nucleotide binding regulation of cell growth protein binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrion organization zinc ion binding membrane integral component of membrane mitochondrial nucleoid identical protein binding negative regulation of apoptotic process antiviral innate immune response |
|
| MG-1-pos-10338515_st |
|
|
|
|
|
|
|
|
|
| TC0X00003412.mm.2 |
Ccdc22 |
coiled-coil domain containing 22 |
X |
-7593808 |
NM_138603, BC011195 NM_138603, BC011195 |
54638 |
17 |
protein binding endosome cellular copper ion homeostasis Golgi to plasma membrane transport cytoplasmic sequestering of NF-kappaB protein transport endocytic recycling cholesterol homeostasis positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling regulation of plasma lipoprotein particle levels cullin family protein binding cullin family protein binding retrograde transport, endosome to plasma membrane positive regulation of ubiquitin-dependent protein catabolic process positive regulation of ubiquitin-dependent protein catabolic process |
|
| MG-1-neg-10338216_st |
|
|
|
|
|
|
|
|
|
| MG-1-pos-10341793_st |
|
|
|
|
|
|
|
|
|
| TC0500001844.mm.2 |
Alox5ap |
arachidonate 5-lipoxygenase activating protein |
5 |
149265003 |
NM_009663, BC026209 NM_009663, BC026209 |
11690 |
43 |
leukotriene production involved in inflammatory response positive regulation of acute inflammatory response arachidonate 5-lipoxygenase activity glutathione transferase activity leukotriene-C4 synthase activity glutathione peroxidase activity protein binding nucleus nuclear envelope nuclear envelope endoplasmic reticulum endoplasmic reticulum cytosol leukotriene metabolic process enzyme activator activity membrane integral component of membrane leukotriene biosynthetic process leukotriene biosynthetic process leukotriene biosynthetic process leukotriene biosynthetic process lipoxygenase pathway enzyme binding nuclear membrane identical protein binding protein-containing complex binding protein N-terminus binding arachidonic acid binding protein homotrimerization cellular response to calcium ion |
|
| TC0400002849.mm.2 |
Megf9 |
multiple EGF-like-domains 9 |
4 |
-70431926 |
NM_172694, BC088994, BC138128, BC138129 NM_172694, BC088994, BC138128, BC138129 NM_172694, BC088994, BC138128, BC138129 NM_172694, BC088994, BC138128, BC138129 |
230316 |
21 |
basement membrane basement membrane animal organ morphogenesis tissue development membrane integral component of membrane cell migration substrate adhesion-dependent cell spreading |
|
| TC1400002231.mm.2 |
Msra |
methionine sulfoxide reductase A |
14 |
-64122620, -64122620, -64122620, -64122620, -64122620 |
NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 NM_001253712, NM_001253714, NM_001253715, NM_001253716, NM_026322, BC014738, BC089311 |
110265 |
79 |
nucleus nucleoplasm cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion cytosol plasma membrane aging peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity actin cytoskeleton membrane oxidoreductase activity cellular response to oxidative stress L-methionine-(S)-S-oxide reductase activity |
|
| TC1700001689.mm.2 |
Nme4 |
NME/NM23 nucleoside diphosphate kinase 4 |
17 |
-26091744 |
NM_019731, BC027277, NME/NM23 NM_019731, BC027277, NME/NM23 NM_019731, BC027277, NME/NM23 |
56520 |
24 |
nucleotide binding nucleoside diphosphate kinase activity ATP binding mitochondrion mitochondrion mitochondrial intermembrane space GTP biosynthetic process UTP biosynthetic process CTP biosynthetic process lipid transport lipid binding nucleotide metabolic process membrane kinase activity phosphorylation transferase activity protein-containing complex binding metal ion binding GTPase binding cardiolipin binding |
00230 00240 01100 |
| TC0900000854.mm.2 |
Pclaf |
PCNA clamp associated factor |
9 |
65890322 |
NM_026515, BC021413, BC096393 NM_026515, BC021413, BC096393 NM_026515, BC021413, BC096393 |
68026 |
31 |
chromatin binding chromatin binding nucleus nucleus cytoplasm centrosome DNA replication DNA repair cellular response to DNA damage stimulus centrosome cycle response to UV translesion synthesis translesion synthesis perinuclear region of cytoplasm regulation of cell cycle |
|
| TC0200000517.mm.2 |
Gle1 |
GLE1 RNA export mediator (yeast) |
2 |
29935408 |
NM_028923, BC026797 NM_028923, BC026797 |
74412 |
20 |
inositol hexakisphosphate binding phospholipid binding nucleus nuclear envelope nuclear pore nucleolus cytoplasm centrosome centriole cytosol mRNA export from nucleus regulation of translational initiation regulation of translational termination protein transport poly(A)+ mRNA export from nucleus translation initiation factor binding nuclear membrane ciliary basal body identical protein binding nuclear pore cytoplasmic filaments mRNA transport |
|
| TC1700001805.mm.2 |
Glo1 |
glyoxalase 1 |
17 |
-30592861 |
NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432 NM_001113560, NM_025374, BC024663, BC081432 |
109801 |
99 |
lactoylglutathione lyase activity lactoylglutathione lyase activity nucleoplasm cytosol plasma membrane carbohydrate metabolic process regulation of transcription by RNA polymerase II glutathione metabolic process zinc ion binding zinc ion binding methylglyoxal metabolic process lyase activity methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione osteoclast differentiation negative regulation of apoptotic process metal ion binding |
00620 |
| TC0400001515.mm.2 |
Yars |
tyrosyl-tRNA synthetase |
4 |
129189902 |
NM_134151, BC013552, BC022143, BC026615 NM_134151, BC013552, BC022143, BC026615 NM_134151, BC013552, BC022143, BC026615 NM_134151, BC013552, BC022143, BC026615 |
107271 |
31 |
tRNA binding nucleotide binding RNA binding aminoacyl-tRNA ligase activity tyrosine-tRNA ligase activity ATP binding cytoplasm cytosol translation tRNA aminoacylation for protein translation tyrosyl-tRNA aminoacylation nuclear body ligase activity |
00970 |
| TC1900000711.mm.2 |
Cnnm2 |
cyclin M2 |
19 |
46761608 |
NM_001102471, NM_033569 NM_001102471, NM_033569 |
94219 |
26 |
ATP binding plasma membrane plasma membrane transport ion transport magnesium ion homeostasis magnesium ion homeostasis magnesium ion transmembrane transporter activity magnesium ion transmembrane transporter activity magnesium ion transport membrane integral component of membrane basolateral plasma membrane basolateral plasma membrane transmembrane transporter activity intracellular membrane-bounded organelle intracellular membrane-bounded organelle |
|
| TC1900001619.mm.2 |
Pcgf6 |
polycomb group ring finger 6 |
19 |
-47033616 |
NM_027654, BC016195, BC089460 NM_027654, BC016195, BC089460 NM_027654, BC016195, BC089460 |
71041 |
35 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II protein binding nucleus nucleus regulation of transcription by RNA polymerase II protein domain specific binding PcG protein complex PcG protein complex PRC1 complex PRC1 complex histone H2A-K119 monoubiquitination histone H2A-K119 monoubiquitination negative regulation of transcription, DNA-templated metal ion binding |
|
| TC0700000991.mm.2 |
Chsy1 |
chondroitin sulfate synthase 1 |
7 |
66109491 |
NM_001081163 |
269941 |
20 |
chondrocyte development extracellular region Golgi apparatus acetylgalactosaminyltransferase activity proximal/distal pattern formation membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups chondroitin sulfate biosynthetic process chondroitin sulfate biosynthetic process chondroitin sulfate biosynthetic process negative regulation of ossification Golgi cisterna membrane positive regulation of smoothened signaling pathway metal ion binding glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity cartilage development sulfation bone morphogenesis |
00532 01100 |
| TC0400001217.mm.2 |
Pdzk1ip1 |
PDZK1 interacting protein 1 |
4 |
115088707 |
NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542 NM_001164557, NM_001164558, NM_026018, BC013542 |
67182 |
24 |
molecular_function biological_process membrane integral component of membrane |
|
| TC0900003342.mm.2 |
Syncrip |
synaptotagmin binding, cytoplasmic RNA interacting protein |
9 |
-88449363, -88455581 |
NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 NM_001284328, NM_019666, NM_019796, BC041148, BC050079, BC080309, BC108363 |
56403 |
66 |
nucleic acid binding RNA binding mRNA binding nucleus spliceosomal complex cytoplasm endoplasmic reticulum mRNA processing poly(A) binding RNA splicing negative regulation of translation intracellular membrane-bounded organelle mRNA 5'-UTR binding CRD-mediated mRNA stabilization CRD-mediated mRNA stabilization CRD-mediated mRNA stability complex CRD-mediated mRNA stability complex catalytic step 2 spliceosome histone pre-mRNA 3'end processing complex cellular response to interferon-gamma GAIT complex ribonucleoprotein complex ribonucleoprotein complex |
|
| TC0300000624.mm.2 |
4930579G24Rik |
RIKEN cDNA 4930579G24 gene |
3 |
79629078 |
NM_029482 |
75939 |
8 |
molecular_function cellular_component cytoplasm biological_process |
|
| TC1000002944.mm.2 |
Nup107 |
nucleoporin 107 |
10 |
-117750642 |
NM_134010, BC057591, BC092261 NM_134010, BC057591, BC092261 NM_134010, BC057591, BC092261 |
103468 |
26 |
chromosome, centromeric region kinetochore posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery nucleus nuclear pore chromosome regulation of transcription, DNA-templated mRNA export from nucleus mRNA export from nucleus protein import into nucleus female gonad development protein transport membrane structural constituent of nuclear pore structural constituent of nuclear pore nuclear pore outer ring nuclear pore outer ring nuclear membrane nuclear periphery mRNA transport nuclear pore complex assembly nephron development |
03013 |
| TC1800001505.mm.2 |
Afg3l2 |
AFG3-like AAA ATPase 2 |
18 |
-67404763 |
NM_027130, BC036999, BC043056 NM_027130, BC036999, BC043056 NM_027130, BC036999, BC043056 |
69597 |
46 |
nucleotide binding metalloendopeptidase activity protein binding ATP binding mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane m-AAA complex proteolysis mitochondrion organization axonogenesis axonogenesis neuromuscular junction development mitochondrial fusion mitochondrial fusion peptidase activity metallopeptidase activity zinc ion binding membrane integral component of membrane protein processing protein autoprocessing hydrolase activity nerve development membrane protein proteolysis mitochondrial protein processing mitochondrial protein processing mitochondrial protein processing calcium import into the mitochondrion regulation of multicellular organism growth cristae formation cristae formation myelination metal ion binding muscle fiber development mitochondrial calcium ion homeostasis righting reflex protein-containing complex assembly |
|
| TC0100002288.mm.2 |
Slc39a10 |
solute carrier family 39 (zinc transporter), member 10 |
1 |
-46807543, -46807543 |
NM_172653, BC052880, BC062918 NM_172653, BC052880, BC062918 NM_172653, BC052880, BC062918 |
227059 |
32 |
negative regulation of B cell apoptotic process zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity plasma membrane integral component of plasma membrane ion transport zinc ion transport cellular zinc ion homeostasis cellular zinc ion homeostasis membrane integral component of membrane metal ion transport positive regulation of B cell proliferation metal ion transmembrane transporter activity positive regulation of B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway transmembrane transport zinc ion import across plasma membrane zinc ion import across plasma membrane positive regulation of protein tyrosine phosphatase activity |
|
| TC1600000464.mm.2 |
Osbpl11 |
oxysterol binding protein-like 11 |
16 |
33185070 |
NM_176840, BC035278 NM_176840, BC035278 |
106326 |
25 |
nucleoplasm endosome Golgi apparatus cytosol lipid transport lipid binding positive regulation of sequestering of triglyceride sterol transporter activity membrane sterol binding intracellular membrane-bounded organelle fat cell differentiation |
|
| TC1600001471.mm.2 |
Xxylt1 |
xyloside xylosyltransferase 1 |
16 |
-30955502 |
NM_198626, BC031419 NM_198626, BC031419 |
268880 |
16 |
magnesium ion binding protein binding endoplasmic reticulum membrane integral component of membrane O-glycan processing O-glycan processing transferase activity transferase activity, transferring glycosyl groups manganese ion binding manganese ion binding integral component of endoplasmic reticulum membrane UDP-xylosyltransferase activity UDP-xylosyltransferase activity metal ion binding |
|
| TC0100000638.mm.2 |
Bcs1l |
BCS1-like (yeast) |
1 |
74588288 |
NM_025784, BC019781 NM_025784, BC019781 |
66821 |
28 |
nucleotide binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrion organization membrane integral component of membrane protein insertion into mitochondrial inner membrane from matrix mitochondrial respiratory chain complex I assembly mitochondrial cytochrome c oxidase assembly mitochondrial respiratory chain complex III assembly mitochondrial respiratory chain complex III assembly mitochondrial respiratory chain complex III assembly |
|
| TC0300000799.mm.2 |
Ilf2 |
interleukin enhancer binding factor 2 |
3 |
90476200 |
NM_026374, BC024718 NM_026374, BC024718 |
67781 |
43 |
DNA binding double-stranded RNA binding nucleus nucleus nucleoplasm nucleolus nucleolus cytoplasm positive regulation of transcription, DNA-templated ribonucleoprotein complex |
|
| TC1800000199.mm.2 |
Elp2 |
elongator acetyltransferase complex subunit 2 |
18 |
24603960 |
NM_021448, BC015284, BC051943 NM_021448, BC015284, BC051943 NM_021448, BC015284, BC051943 |
58523 |
31 |
RNA polymerase II complex binding tRNA wobble uridine modification protein binding nucleus nucleoplasm cytoplasm cytosol transcription elongation factor complex transcription elongation factor complex tRNA processing protein kinase binding elongator holoenzyme complex elongator holoenzyme complex regulation of receptor signaling pathway via JAK-STAT |
|
| TC1100001467.mm.2 |
Phb |
prohibitin |
11 |
95666956 |
NM_008831, BC083354, BC089034 NM_008831, BC083354, BC089034 NM_008831, BC083354, BC089034 |
18673 |
91 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II complement component C3a binding complement component C3b binding immunoglobulin production transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial inner membrane early endosome plasma membrane plasma membrane integral component of plasma membrane regulation of transcription, DNA-templated mitochondrion organization mitochondrion organization activation of phospholipase C activity protein C-terminus binding negative regulation of cell population proliferation cell surface cell surface positive regulation of gene expression positive regulation of cell death negative regulation of transcription by competitive promoter binding postsynaptic density membrane histone deacetylation enzyme binding CD40 signaling pathway mitochondrial crista negative regulation of cell growth extrinsic component of mitochondrial outer membrane proteinase activated receptor binding interleukin-17 production mitochondrial prohibitin complex RIG-I signaling pathway B cell activation negative regulation of protein catabolic process histone deacetylase binding negative regulation of apoptotic process myelin sheath modulation by host of viral RNA genome replication positive regulation of G protein-coupled receptor signaling pathway negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of complement activation viral entry into host cell protein heterodimerization activity positive regulation of smooth muscle cell proliferation protein stabilization progesterone receptor signaling pathway positive regulation of protein kinase B signaling negative regulation of androgen receptor signaling pathway negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade cellular response to interleukin-6 DNA biosynthetic process T-helper 17 type immune response extrinsic component of presynaptic active zone membrane glutamatergic synapse GABA-ergic synapse antiviral innate immune response positive regulation of NIK/NF-kappaB signaling activation of protein kinase C activity negative regulation of glucocorticoid receptor signaling pathway |
|
| TC0700002744.mm.2 |
Zfp146 |
zinc finger protein 146 |
7 |
-30160486 |
NM_011980, BC127038, BC127039 NM_011980, BC127038, BC127039 NM_011980, BC127038, BC127039 |
26465 |
22 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nucleic acid binding DNA binding nucleus nucleolus cytosol regulation of transcription by RNA polymerase II metal ion binding |
|
| TC0300000283.mm.2 |
Spata5 |
spermatogenesis associated 5 |
3 |
37419949 |
NM_001163511, NM_021343, BC145302 NM_001163511, NM_021343, BC145302 NM_001163511, NM_021343, BC145302 |
57815 |
21 |
nucleotide binding ATP binding cytoplasm cytoplasm mitochondrion spindle multicellular organism development spermatogenesis brain development hydrolase activity ATPase activity cell differentiation |
03008 |
| TC0400001034.mm.2 |
Ak4 |
adenylate kinase 4 |
4 |
101419288, 101419320, 101419702, 101419311 |
NM_001177602, NM_001177604, NM_001177605, NM_009647, BC086663 NM_001177602, NM_001177604, NM_001177605, NM_009647, BC086663 NM_001177602, NM_001177604, NM_001177605, NM_009647, BC086663 NM_001177602, NM_001177604, NM_001177605, NM_009647, BC086663 NM_001177602, NM_001177604, NM_001177605, NM_009647, BC086663 |
11639 |
31 |
nucleotide binding regulation of oxidative phosphorylation adenylate kinase activity nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity ATP binding GTP binding cytoplasm mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix nucleobase-containing compound metabolic process nucleoside diphosphate phosphorylation nucleoside diphosphate phosphorylation nucleoside triphosphate biosynthetic process nucleoside triphosphate biosynthetic process kinase activity phosphorylation transferase activity phosphotransferase activity, phosphate group as acceptor nucleobase-containing compound kinase activity AMP metabolic process AMP metabolic process ATP metabolic process GTP metabolic process nucleoside triphosphate adenylate kinase activity cellular response to hypoxia regulation of ATP biosynthetic process |
00230 01100 |
| TC0300003221.mm.2 |
Wdr77 |
WD repeat domain 77 |
3 |
105959497 |
NM_027432, BC005755 NM_027432, BC005755 |
70465 |
39 |
protein binding nucleus nucleoplasm nucleoplasm cytoplasm Golgi apparatus cytosol cytosol regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II pole plasm assembly positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation methyl-CpG binding methyl-CpG binding nuclear receptor coactivator activity nuclear receptor coactivator activity methylosome methylosome pole plasm secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development negative regulation of epithelial cell proliferation involved in prostate gland development negative regulation of epithelial cell proliferation involved in prostate gland development |
|
| TC0900000509.mm.2 |
Slc37a4 |
solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
9 |
44396945, 44398353, 44397098 |
NM_008063, BC075655 NM_008063, BC075655 |
14385 |
35 |
neutrophil homeostasis cytokine production myeloid progenitor cell differentiation glycogen metabolic process lactate metabolic process triglyceride metabolic process cellular calcium ion homeostasis steroid metabolic process response to organic cyclic compound glucose-6-phosphate transmembrane transporter activity hexose phosphate transport glucose-6-phosphate transport glucose-6-phosphate transport glucose-6-phosphate transport glucose-6-phosphate transport integral component of endoplasmic reticulum membrane neutrophil chemotaxis negative regulation of chemokine production post-embryonic hemopoiesis phosphate ion transmembrane transport glucose homeostasis glucose homeostasis cholesterol homeostasis positive regulation of catalytic activity intracellular membrane-bounded organelle respiratory burst glucose 6-phosphate:inorganic phosphate antiporter activity |
04973 |
| TC1000002639.mm.2 |
Parpbp |
PARP1 binding protein |
10 |
-88091397 |
NM_029249, BC070476 NM_029249, BC070476 |
75317 |
21 |
chromatin chromatin DNA binding protein binding nucleus nucleoplasm cytoplasm DNA repair cellular response to DNA damage stimulus negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination |
|
| TC1300002360.mm.2 |
Polr3g |
polymerase (RNA) III (DNA directed) polypeptide G |
13 |
-81673836 |
NM_001081176, BC030063, BC066818 NM_001081176, BC030063, BC066818 NM_001081176, BC030063, BC066818 |
67486 |
24 |
immune system process chromatin binding chromatin binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex cytoplasm cytosol transcription by RNA polymerase III cell population proliferation cell population proliferation cell population proliferation nuclear body positive regulation of interferon-beta production innate immune response positive regulation of innate immune response defense response to virus |
00230 00240 01100 03020 04623 |
| TC0800000704.mm.2 |
Ints10 |
integrator complex subunit 10 |
8 |
68793928 |
NM_027590, BC031923 NM_027590, BC031923 |
70885 |
22 |
molecular_function nucleus snRNA processing integrator complex |
|
| TC0200002731.mm.2 |
Gm2026 |
predicted gene 2026 |
2 |
-175192004, -175419390, 175640390, 175737941, -176470368, -176619932 |
NM_001177543 |
100039060 |
9 |
cellular_component |
|
| TC1400002058.mm.2 |
Haus4 |
HAUS augmin-like complex, subunit 4 |
14 |
-54541784 |
NM_145462, BC004644, BC011095 NM_145462, BC004644, BC011095 NM_145462, BC004644, BC011095 |
219072 |
21 |
cytoplasm centrosome cytoskeleton microtubule cell cycle centrosome cycle centrosome cycle microtubule minus-end binding spindle assembly spindle assembly cell division HAUS complex HAUS complex mitotic spindle microtubule |
|
| TC1400000347.mm.2 |
Ercc6 |
excision repair cross-complementing rodent repair deficiency, complementation group 6 |
14 |
32513520 |
NM_001081221, BC167234 NM_001081221, BC167234 |
319955 |
84 |
single strand break repair DNA damage checkpoint nucleotide binding response to superoxide positive regulation of defense response to virus by host DNA binding chromatin binding helicase activity ATP binding nucleus nucleus nucleoplasm nucleolus DNA repair DNA repair DNA repair transcription-coupled nucleotide-excision repair transcription-coupled nucleotide-excision repair transcription-coupled nucleotide-excision repair base-excision repair pyrimidine dimer repair transcription elongation from RNA polymerase I promoter cellular response to DNA damage stimulus response to oxidative stress response to oxidative stress activation of JNKK activity activation of JUN kinase activity nervous system development protein C-terminus binding transcription elongation factor complex DNA-dependent ATPase activity DNA-dependent ATPase activity intrinsic apoptotic signaling pathway in response to DNA damage response to UV response to UV response to toxic substance response to X-ray response to UV-B response to gamma radiation positive regulation of gene expression nuclear body hydrolase activity neurogenesis neuron differentiation protein tyrosine kinase activator activity neuron projection development regulation of DNA-templated transcription, elongation positive regulation of DNA-templated transcription, elongation positive regulation of peptidyl-serine phosphorylation of STAT protein multicellular organism growth ATP-dependent chromatin remodeling sequence-specific DNA binding protein-containing complex binding photoreceptor cell maintenance positive regulation of DNA repair protein N-terminus binding positive regulation of transcription initiation from RNA polymerase II promoter positive regulation of transcription initiation from RNA polymerase II promoter RNA polymerase binding site of DNA damage double-strand break repair via classical nonhomologous end joining positive regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via nonhomologous end joining |
03420 |
| TC0200003717.mm.2 |
Mettl8 |
methyltransferase like 8 |
2 |
-70964560, -70964561 |
NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960 NM_001110512, NM_145524, BC004636, BC057960 |
228019 |
18 |
histone acetyltransferase activity nucleus cytoplasm skeletal muscle tissue development methyltransferase activity mRNA methyltransferase activity mRNA methyltransferase activity histone acetylation transferase activity methylation fat cell differentiation tRNA (cytosine-3-)-methyltransferase activity mRNA methylation mRNA methylation |
|
| TC0X00001634.mm.2 |
Phka2 |
phosphorylase kinase alpha 2 |
X |
160502161, 160502161, 160502161 |
NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040 NM_001177878, NM_001177879, NM_172783, BC050040 |
110094 |
27 |
catalytic activity calmodulin binding plasma membrane phosphorylase kinase complex phosphorylase kinase complex carbohydrate metabolic process glycogen metabolic process protein phosphorylation membrane |
04020 04910 |
| TC1200001832.mm.2 |
Fkbp3 |
FK506 binding protein 3 |
12 |
-65062431 |
NM_013902, BC002122, FK506 NM_013902, BC002122, FK506 NM_013902, BC002122, FK506 |
30795 |
31 |
peptidyl-prolyl cis-trans isomerase activity protein binding nucleus isomerase activity |
|
| TC0500002095.mm.2 |
Prkag2 |
protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
5 |
-24862734, -24862734, -24862734 |
NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283 NM_001170555, NM_001170556, NM_145401, BC015283 |
108099 |
37 |
nucleotide binding AMP-activated protein kinase activity AMP-activated protein kinase activity cAMP-dependent protein kinase inhibitor activity ATP binding nucleus nucleoplasm cytoplasm cytosol glycogen metabolic process regulation of glycolytic process protein phosphorylation negative regulation of protein kinase activity lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process cAMP-dependent protein kinase regulator activity phosphorylase kinase regulator activity positive regulation of peptidyl-threonine phosphorylation AMP binding AMP binding regulation of fatty acid metabolic process protein kinase regulator activity protein kinase binding protein kinase binding protein kinase activator activity nucleotide-activated protein kinase complex nucleotide-activated protein kinase complex adenyl ribonucleotide binding intracellular signal transduction cellular response to glucose starvation ADP binding positive regulation of protein kinase activity regulation of catalytic activity regulation of catalytic activity regulation of protein serine/threonine kinase activity |
04910 04920 05410 |
| TC0800003160.mm.2 |
Ccsap |
centriole, cilia and spindle associated protein |
8 |
-123840843, -123839973, -123839973 |
NM_028536, BC024705, BC036300 NM_028536, BC024705, BC036300 NM_028536, BC024705, BC036300 |
73420 |
14 |
cytoplasm centrosome centriole centriole spindle spindle cytoskeleton microtubule cilium axoneme axoneme cell cycle multicellular organism development microtubule binding microtubule binding axon axon ciliary transition zone ciliary transition zone ciliary basal body ciliary basal body cell projection cell division mitotic spindle astral microtubule mitotic spindle regulation of mitotic spindle assembly regulation of mitotic spindle assembly mitotic spindle microtubule depolymerization |
|
| TC0600002353.mm.2 |
Pyurf |
Pigy upstream reading frame |
6 |
-57684738 |
NM_025574, BC029232 NM_025574, BC029232 |
66459 |
16 |
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex molecular_function mitochondrion endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane GPI anchor biosynthetic process GPI anchor biosynthetic process GPI anchor biosynthetic process positive regulation of metabolic process |
|
| TC1900001472.mm.2 |
Noc3l |
NOC3 like DNA replication regulator |
19 |
-38788127 |
NM_021315, BC031132 NM_021315, BC031132 |
57753 |
29 |
chromatin binding nucleus nucleoplasm nucleolus nucleolus nucleolus mitochondrion DNA replication initiation nuclear speck fat cell differentiation |
|
| TC0100003783.mm.2 |
Cenpf |
centromere protein F |
1 |
-189640613 |
NM_001081363 |
108000 |
56 |
mitotic cell cycle mitotic cell cycle chromosome, centromeric region chromosome, centromeric region spindle pole spindle pole condensed chromosome outer kinetochore kidney development nucleus nucleus nucleus nucleus nuclear envelope nucleoplasm cytoplasm centrosome spindle axoneme chromosome segregation protein C-terminus binding transcription factor binding regulation of G2/M transition of mitotic cell cycle regulation of G2/M transition of mitotic cell cycle protein transport regulation of striated muscle tissue development nuclear matrix ventricular system development midbody ciliary basal body protein homodimerization activity pronucleus negative regulation of transcription, DNA-templated metaphase plate congression metaphase plate congression dynein complex binding dynein complex binding ciliary transition fiber ciliary transition fiber |
|
| TC0800000424.mm.2 |
Ppp1r3b |
protein phosphatase 1, regulatory subunit 3B |
8 |
35375758, 35376661 |
NM_177741, BC079666, XR_105198 NM_177741, BC079666, XR_105198 NM_177741, BC079666, XR_105198 |
244416 |
20 |
protein phosphatase type 1 complex protein phosphatase type 1 complex phosphoprotein phosphatase activity carbohydrate metabolic process glycogen metabolic process regulation of glycogen biosynthetic process regulation of glycogen biosynthetic process regulation of glycogen catabolic process protein phosphatase 1 binding protein phosphatase regulator activity enzyme binding glycogen granule intracellular membrane-bounded organelle [phosphorylase] phosphatase activity glycogen binding |
04910 |
| TC0400001006.mm.2 |
Alg6 |
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase) |
4 |
99715629 |
NM_001081264, BC050854 NM_001081264, BC050854 |
320438 |
15 |
endoplasmic reticulum endoplasmic reticulum membrane protein N-linked glycosylation protein N-linked glycosylation dolichol-linked oligosaccharide biosynthetic process oligosaccharide-lipid intermediate biosynthetic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups transferase activity, transferring hexosyl groups dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity glucosyltransferase activity |
00510 01100 |
| TC1600000700.mm.2 |
Cip2a |
cell proliferation regulating inhibitor of protein phosphatase 2A |
16 |
48994187 |
NM_172616, BC137719 NM_172616, BC137719 |
224171 |
28 |
cytoplasm cytosol plasma membrane spermatogenesis membrane integral component of membrane protein homodimerization activity positive regulation of neural precursor cell proliferation |
|
| TC0200005350.mm.2 |
|
|
|
|
NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process |
|
| TC0X00000454.mm.2 |
Stk26 |
serine/threonine kinase 26 |
X |
50841370 |
NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193 NM_133729, BC005708, BC132438, BC138193 |
70415 |
20 |
Golgi membrane nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity ATP binding cytoplasm Golgi apparatus Golgi-associated vesicle cytosol protein phosphorylation apoptotic process cellular response to starvation membrane kinase activity phosphorylation apical plasma membrane transferase activity microvillus assembly negative regulation of cell migration response to hydrogen peroxide identical protein binding protein homodimerization activity regulation of apoptotic process protein autophosphorylation metal ion binding perinuclear region of cytoplasm cell periphery regulation of hydrogen peroxide-induced cell death |
|
| TC1400000980.mm.2 |
Entpd4 |
ectonucleoside triphosphate diphosphohydrolase 4 |
14 |
69337150, 69555400 |
NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 NM_026174, BC043134, XM_003688928, XM_003688929, XM_003688930, XM_003688931 |
67464 |
23 |
Golgi membrane autophagosome membrane guanosine-diphosphatase activity guanosine-diphosphatase activity Golgi apparatus UDP catabolic process nucleoside diphosphate catabolic process membrane nucleoside-diphosphatase activity nucleoside-diphosphatase activity nucleoside-triphosphatase activity integral component of Golgi membrane cytidine-diphosphatase activity CTPase activity uridine-diphosphatase activity uridine-diphosphatase activity integral component of autophagosome membrane |
00230 00240 04142 |
| MG-1-pos-10341055_st |
|
|
|
|
|
|
|
|
|
| TC1000000015.mm.2 |
Mthfd1l |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like |
10 |
3973074, 3973074 |
NM_001170785, NM_001170786, NM_172308, BC030437 NM_001170785, NM_001170786, NM_172308, BC030437 NM_001170785, NM_001170786, NM_172308, BC030437 NM_001170785, NM_001170786, NM_172308, BC030437 |
270685 |
33 |
nucleotide binding neural tube closure formate-tetrahydrofolate ligase activity methylenetetrahydrofolate dehydrogenase (NADP+) activity ATP binding mitochondrion mitochondrion mitochondrion mitochondrion cytosol one-carbon metabolic process folic acid-containing compound metabolic process 10-formyltetrahydrofolate biosynthetic process formate metabolic process ligase activity tetrahydrofolate interconversion protein homodimerization activity embryonic neurocranium morphogenesis embryonic viscerocranium morphogenesis |
00670 01100 |
| TC0600003074.mm.2 |
Slc2a3 |
solute carrier family 2 (facilitated glucose transporter), member 3 |
6 |
-122727808 |
NM_011401, BC034122, BC058811 NM_011401, BC034122, BC058811 NM_011401, BC034122, BC058811 |
20527 |
133 |
acrosomal membrane transporter activity glucose transmembrane transporter activity glucose binding cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane integral component of plasma membrane caveola carbohydrate transport monosaccharide transmembrane transporter activity membrane integral component of membrane galactoside binding kinase binding transmembrane transporter activity synaptic vesicle membrane xylose binding dehydroascorbic acid transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity cell projection D-glucose transmembrane transporter activity D-glucose transmembrane transporter activity transmembrane transport dehydroascorbic acid transport glucose import across plasma membrane glutamatergic synapse integral component of synaptic membrane transport across blood-brain barrier glucose transmembrane transport glucose transmembrane transport glucose transmembrane transport |
|
| TC0600000962.mm.2 |
Smyd5 |
SET and MYND domain containing 5 |
6 |
85431975 |
NM_144918, BC016525 NM_144918, BC016525 |
232187 |
22 |
molecular_function cellular_component biological_process methyltransferase activity transferase activity methylation metal ion binding |
|
| TC1100002593.mm.2 |
Thg1l |
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) |
11 |
-45945305, -45945305 |
NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561 NM_001080969, BC092541, BC115560, BC115561 |
66628 |
16 |
nucleotide binding magnesium ion binding guanyl-nucleotide exchange factor activity ATP binding GTP binding cytoplasm mitochondrion tRNA modification response to oxidative stress tRNA processing tRNA processing mitochondrial fusion tRNA guanylyltransferase activity tRNA guanylyltransferase activity transferase activity nucleotidyltransferase activity identical protein binding metal ion binding protein homotetramerization stress-induced mitochondrial fusion transferase complex |
|
| TC1200000869.mm.2 |
Gstz1 |
glutathione transferase zeta 1 (maleylacetoacetate isomerase) |
12 |
87157602, 87147706, 87147164 |
NM_001252555, NM_001252556, NM_010363, BC031777 NM_001252555, NM_001252556, NM_010363, BC031777 NM_001252555, NM_001252556, NM_010363, BC031777 NM_001252555, NM_001252556, NM_010363, BC031777 |
14874 |
26 |
catalytic activity glutathione transferase activity glutathione transferase activity glutathione transferase activity cytoplasm mitochondrion mitochondrion mitochondrion L-phenylalanine catabolic process L-phenylalanine catabolic process tyrosine catabolic process glutathione metabolic process glutathione metabolic process metabolic process aromatic amino acid family metabolic process maleylacetoacetate isomerase activity maleylacetoacetate isomerase activity transferase activity isomerase activity identical protein binding protein homodimerization activity |
00350 00480 00980 00982 01100 |
| TC0100003477.mm.2 |
|
|
|
|
|
|
|
|
|
| TC1000001020.mm.2 |
Tcp11l2 |
t-complex 11 (mouse) like 2 |
10 |
84576946 |
NM_146008, BC029663 NM_146008, BC029663 |
216198 |
14 |
molecular_function cellular_component signal transduction |
|
| TC1100001849.mm.2 |
Kcnj2 |
potassium inwardly-rectifying channel, subfamily J, member 2 |
11 |
111066163 |
NM_008425, BC137841, BC137842 NM_008425, BC137841, BC137842 NM_008425, BC137841, BC137842 |
16518 |
120 |
inward rectifier potassium channel activity inward rectifier potassium channel activity voltage-gated ion channel activity protein binding phosphatidylinositol-4,5-bisphosphate binding smooth endoplasmic reticulum rough endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane ion transport potassium ion transport voltage-gated potassium channel complex intercalated disc regulation of skeletal muscle contraction via regulation of action potential magnesium ion transport membrane integral component of membrane T-tubule dendrite intrinsic component of membrane regulation of ion transmembrane transport identical protein binding identical protein binding neuronal cell body dendritic spine protein homotetramerization relaxation of cardiac muscle regulation of membrane repolarization potassium ion transmembrane transport cardiac muscle cell action potential cardiac muscle cell action potential involved in contraction regulation of cardiac muscle cell contraction voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization membrane repolarization during action potential membrane repolarization during cardiac muscle cell action potential regulation of heart rate by cardiac conduction relaxation of skeletal muscle positive regulation of potassium ion transmembrane transport potassium ion import across plasma membrane potassium ion import across plasma membrane |
04971 |
| TC0300001987.mm.2 |
Exosc8 |
exosome component 8 |
3 |
-54728678 |
NM_001163570, NM_027148, BC059089 NM_001163570, NM_027148, BC059089 NM_001163570, NM_027148, BC059089 |
69639 |
24 |
nuclear exosome (RNase complex) cytoplasmic exosome (RNase complex) exosome (RNase complex) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) fibrillar center RNA binding nucleus nucleoplasm chromosome cytoplasm cytosol rRNA processing RNA processing RNA catabolic process rRNA catabolic process nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' U1 snRNA 3'-end processing U4 snRNA 3'-end processing U5 snRNA 3'-end processing mRNA 3'-UTR AU-rich region binding identical protein binding intracellular membrane-bounded organelle exonucleolytic catabolism of deadenylated mRNA nuclear mRNA surveillance nuclear polyadenylation-dependent rRNA catabolic process nuclear polyadenylation-dependent tRNA catabolic process nuclear polyadenylation-dependent mRNA catabolic process |
03018 |
| TC0500003637.mm.2 |
Slc7a1 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
5 |
-148327409, -148327409 |
NM_007513, BC145779, BC145781 NM_007513, BC145779, BC145781 NM_007513, BC145779, BC145781 |
11987 |
55 |
L-ornithine transmembrane transporter activity L-histidine transmembrane transporter activity plasma membrane plasma membrane amino acid transport basal plasma membrane amino acid transmembrane transporter activity amino acid transmembrane transporter activity basic amino acid transmembrane transporter activity arginine transmembrane transporter activity arginine transmembrane transporter activity arginine transmembrane transporter activity L-lysine transmembrane transporter activity L-amino acid transport arginine transport arginine transport lysine transport ornithine transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane transmembrane transporter activity regulation of TOR signaling protein-containing complex positive regulation of T cell proliferation transmembrane transport L-arginine transmembrane transporter activity amino acid import across plasma membrane L-arginine import across plasma membrane L-arginine import across plasma membrane L-ornithine transmembrane transport L-histidine import across plasma membrane arginine transmembrane transport basic amino acid transmembrane transport |
|
| TC0100001787.mm.2 |
Eprs |
glutamyl-prolyl-tRNA synthetase |
1 |
185363043 |
NM_029735, BC141049 NM_029735, BC141049 |
107508 |
41 |
nucleotide binding RNA binding catalytic activity aminoacyl-tRNA ligase activity glutamate-tRNA ligase activity proline-tRNA ligase activity proline-tRNA ligase activity proline-tRNA ligase activity protein binding ATP binding cytoplasm cytoplasm cytosol plasma membrane translation regulation of translation tRNA aminoacylation for protein translation glutamyl-tRNA aminoacylation prolyl-tRNA aminoacylation prolyl-tRNA aminoacylation prolyl-tRNA aminoacylation metabolic process zinc ion binding membrane ligase activity aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex negative regulation of translation negative regulation of translation cellular response to insulin stimulus RNA stem-loop binding identical protein binding protein homodimerization activity tRNA aminoacylation metal ion binding GTPase binding cellular response to interferon-gamma cellular response to interferon-gamma GAIT complex regulation of long-chain fatty acid import into cell regulation of long-chain fatty acid import into cell ribonucleoprotein complex |
00860 00970 01100 |
| TC1000002686.mm.2 |
Nedd1 |
neural precursor cell expressed, developmentally down-regulated gene 1 |
10 |
-92684744 |
NM_008682, BC052430, BC066870 NM_008682, BC052430, BC066870 NM_008682, BC052430, BC066870 |
17997 |
34 |
pericentriolar material pericentriolar material spindle pole spindle pole gamma-tubulin ring complex, centrosomal nucleoplasm cytoplasm centrosome centrosome centriole centriole cytoskeleton plasma membrane microtubule depolymerization cell cycle microtubule polymerization or depolymerization ciliary basal body ciliary basal body apical part of cell cell division regulation of establishment of protein localization protein localization to centrosome |
|
| TC1300001445.mm.2 |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
13 |
-12186539 |
NM_001081128, BC145683, BC145685 NM_001081128, BC145683, BC145685 NM_001081128, BC145683, BC145685 |
238505 |
25 |
folic acid binding cytoplasm cytosol cytosol protein methylation methionine metabolic process methyltransferase activity zinc ion binding cellular amino acid biosynthetic process methionine synthase activity methionine synthase activity methionine synthase activity methionine biosynthetic process methionine biosynthetic process cobalamin metabolic process amino acid binding transferase activity axon regeneration cobalamin binding methylation pteridine-containing compound metabolic process cellular metabolic process tetrahydrofolate metabolic process metal ion binding response to axon injury homocysteine metabolic process cellular response to nitric oxide |
00270 00450 00670 01100 |
| MG-1-pos-10338434_st |
|
|
|
|
|
|
|
|
|
| TC0X00001651.mm.2 |
Rbbp7 |
retinoblastoma binding protein 7, chromatin remodeling factor |
X |
162760371 |
NM_009031, BC003785 NM_009031, BC003785 |
245688 |
63 |
negative regulation of transcription by RNA polymerase II RNA binding protein binding nucleus nucleus nucleoplasm nucleoplasm cytosol DNA replication chromatin organization chromatin remodeling NuRD complex NuRD complex negative regulation of cell growth ESC/E(Z) complex ESC/E(Z) complex negative regulation of transcription, DNA-templated cellular heat acclimation cellular heat acclimation |
|
| TC0100003483.mm.2 |
Mgst3 |
microsomal glutathione S-transferase 3 |
1 |
-167371965 |
NM_025569, BC029669 NM_025569, BC029669 |
66447 |
28 |
glutathione transferase activity leukotriene-C4 synthase activity glutathione peroxidase activity glutathione peroxidase activity nuclear envelope endoplasmic reticulum lipid metabolic process membrane integral component of membrane oxidoreductase activity transferase activity leukotriene biosynthetic process identical protein binding intracellular membrane-bounded organelle |
00480 00980 00982 |
| TC0200003753.mm.2 |
Gpr155 |
G protein-coupled receptor 155 |
2 |
-73341505 |
NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 NM_001190297, NM_001276443, NM_001276444, BC115698, NM_001080707 |
68526 |
13 |
molecular_function cognition |
|
| TC0500001548.mm.2 |
Gtf2ird2 |
GTF2I repeat domain containing 2 |
5 |
134184037 |
NM_053266, BC132157, BC132159 NM_053266, BC132157, BC132159 NM_053266, BC132157, BC132159 |
114674 |
18 |
DNA binding protein binding nucleus nucleus transition between fast and slow fiber |
|
| TC0200005339.mm.2 |
|
|
|
|
NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 NM_001101804, NM_001177543, NM_001256480, NM_001099349, NM_001100415, NM_001100416 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process |
|
| TC0100003210.mm.2 |
Rgs18 |
regulator of G-protein signaling 18 |
1 |
-144752682 |
NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546 NM_022881, BC099387, BC132544, BC132546 |
64214 |
21 |
GTPase activator activity cytoplasm G protein-coupled receptor signaling pathway regulation of G protein-coupled receptor signaling pathway negative regulation of signal transduction |
|
| TC0100002899.mm.2 |
Kdsr |
3-ketodihydrosphingosine reductase |
1 |
-106720409, -106731201 |
NM_027534, BC023820 NM_027534, BC023820 |
70750 |
23 |
endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process sphingolipid metabolic process 3-keto-sphinganine metabolic process 3-keto-sphinganine metabolic process membrane integral component of membrane oxidoreductase activity sphingolipid biosynthetic process sphingolipid biosynthetic process 3-dehydrosphinganine reductase activity 3-dehydrosphinganine reductase activity |
00600 01100 |
| TC0900002018.mm.2 |
Hyls1 |
HYLS1, centriolar and ciliogenesis associated |
9 |
-35560820 |
NM_029762, BC035953 NM_029762, BC035953 |
76832 |
12 |
molecular_function nucleus cytoplasm centrosome centriole cytosol cytoskeleton plasma membrane cell projection organization cell projection cilium assembly non-motile cilium |
|
| TC1900000312.mm.2 |
Prune2 |
prune homolog 2 |
19 |
16956117 |
NM_181348, BC095978 NM_181348, BC095978 |
353211 |
29 |
exopolyphosphatase activity cytoplasm polyphosphate catabolic process apoptotic process pyrophosphatase activity |
|
| TC1100002486.mm.2 |
Npm1 |
nucleophosmin 1 |
11 |
-33152497, -33154924 |
NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 NM_001252260, NM_001252261, NM_008722, BC054755, BC085278, BC089546, BC090843, BC092378 |
18148 |
155 |
ribosomal large subunit export from nucleus ribosomal large subunit export from nucleus ribosomal small subunit export from nucleus ribosomal small subunit export from nucleus cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) core promoter sequence-specific DNA binding regulation of cell growth granular component p53 binding nucleic acid binding DNA binding chromatin binding transcription coactivator activity RNA binding RNA binding RNA binding protein kinase inhibitor activity protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding nucleus nucleus nucleoplasm nucleoplasm nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytoplasm cytoplasm centrosome centrosome centrosome cytosol cytoskeleton DNA repair nucleosome assembly chromatin remodeling rRNA export from nucleus rRNA export from nucleus rRNA export from nucleus cell volume homeostasis cell volume homeostasis nucleocytoplasmic transport nucleocytoplasmic transport centrosome cycle cell aging protein localization protein localization transcription factor binding positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation rRNA transcription posttranscriptional regulation of gene expression negative regulation of gene expression negative regulation of cardiac muscle cell apoptotic process regulation of centrosome duplication regulation of centrosome duplication positive regulation of centrosome duplication negative regulation of centrosome duplication large ribosomal subunit small ribosomal subunit nuclear matrix nuclear speck rRNA binding enzyme binding protein kinase binding Tat protein binding positive regulation of cellular biosynthetic process positive regulation of cellular biosynthetic process positive regulation of protein ubiquitination spindle pole centrosome regulation of protein stability protein destabilization regulation of endodeoxyribonuclease activity protein-containing complex protein-DNA complex activating transcription factor binding cellular response to UV ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis histone binding histone binding identical protein binding identical protein binding protein homodimerization activity ribosomal large subunit binding ribosomal small subunit binding negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of catalytic activity protein kinase B binding regulation of DNA damage response, signal transduction by p53 class mediator regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of protein kinase activity by regulation of protein phosphorylation positive regulation of translation positive regulation of DNA replication positive regulation of protein kinase activity positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of centriole replication protein N-terminus binding negative regulation of mRNA splicing, via spliceosome negative regulation of epithelial cell proliferation protein stabilization protein stabilization positive regulation of DNA metabolic process NF-kappaB binding unfolded protein binding positive regulation of NF-kappaB transcription factor activity regulation of cell cycle regulation of endoribonuclease activity regulation of eIF2 alpha phosphorylation by dsRNA positive regulation of DNA-directed DNA polymerase activity regulation of mRNA stability involved in cellular response to UV positive regulation of cell cycle G2/M phase transition positive regulation of protein localization to nucleolus ribonucleoprotein complex ribonucleoprotein complex |
|
| TC0200004547.mm.2 |
Ncaph |
non-SMC condensin I complex, subunit H |
2 |
-127103809 |
NM_144818, BC021499, BC025060 NM_144818, BC021499, BC025060 NM_144818, BC021499, BC025060 |
215387 |
31 |
condensin complex condensin complex condensin complex condensin complex chromatin binding chromatin binding nucleus nucleoplasm chromosome cytoplasm cytosol cell cycle mitotic chromosome condensation mitotic chromosome condensation female meiotic nuclear division meiotic chromosome condensation meiotic chromosome condensation chromosome condensation DNA topoisomerase binding meiotic chromosome segregation cell division female meiosis chromosome separation DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity |
|
| TC1800001654.mm.2 |
Rbfa |
ribosome binding factor A |
18 |
-80192263 |
NM_199197, BC064066 NM_199197, BC064066 |
68731 |
17 |
molecular_function cellular_component mitochondrion rRNA processing |
|
| TC1300000792.mm.2 |
Zfp369 |
zinc finger protein 369 |
13 |
65278853 |
NM_178364, BC167204 NM_178364, BC167204 |
170936 |
19 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleic acid binding DNA binding chromatin binding DNA-binding transcription factor activity neurotrophin p75 receptor binding protein binding intracellular anatomical structure nucleus cytoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II apoptotic process sequence-specific DNA binding metal ion binding regulation of cell cycle sequence-specific double-stranded DNA binding |
04722 |
| TC1700002656.mm.2 |
Lrpprc |
leucine-rich PPR-motif containing |
17 |
-84705246 |
NM_028233, BC059862 NM_028233, BC059862 |
72416 |
44 |
condensed nuclear chromosome negative regulation of mitochondrial RNA catabolic process negative regulation of mitochondrial RNA catabolic process DNA binding single-stranded DNA binding RNA binding protein binding nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion cytoskeleton microtubule membrane ubiquitin protein ligase binding mitochondrial nucleoid perinuclear region of cytoplasm beta-tubulin binding mRNA transport regulation of mitochondrial translation ribonucleoprotein complex |
|
| MG-1-pos-10344497_st |
|
|
|
|
|
|
|
|
|
| TC1400000350.mm.2 |
Tmem273 |
transmembrane protein 273 |
14 |
32785962 |
NM_001163616 |
69069 |
8 |
molecular_function cellular_component biological_process |
|
| TC0700003608.mm.2 |
Cpeb1 |
cytoplasmic polyadenylation element binding protein 1 |
7 |
-81347025, -81347025 |
NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476 NM_001252525, NM_001252526, NM_007755, BC125476 |
12877 |
64 |
translation repressor activity, mRNA regulatory element binding translation repressor activity, mRNA regulatory element binding nucleic acid binding RNA binding mRNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm centrosome cytosol mRNA processing regulation of translation synaptonemal complex assembly translation factor activity, RNA binding negative regulation of cell population proliferation positive regulation of neuron projection development postsynaptic density membrane negative regulation of translation cell junction positive regulation of cell migration growth cone cellular response to insulin stimulus mRNA 3'-UTR AU-rich region binding neuron projection ribosome binding neuronal cell body translation regulator activity synapse positive regulation of translation metal ion binding regulation of neuronal synaptic plasticity perinuclear region of cytoplasm mRNA transport positive regulation of nitric-oxide synthase biosynthetic process cellular response to amino acid stimulus cellular response to hypoxia cellular response to hypoxia meiotic spindle positive regulation of mRNA polyadenylation messenger ribonucleoprotein complex negative regulation of cytoplasmic translation negative regulation of cytoplasmic translation negative regulation of cytoplasmic translation |
04114 04320 04914 |
| TC0100000456.mm.2 |
Nop58 |
NOP58 ribonucleoprotein |
1 |
59685005 |
NM_018868, BC076604, BC085135 NM_018868, BC076604, BC085135 NM_018868, BC076604, BC085135 |
55989 |
31 |
TFIID-class transcription factor complex binding fibrillar center nucleus nucleoplasm nucleolus sno(s)RNA-containing ribonucleoprotein complex cytosol Cajal body snoRNA binding snoRNA binding box C/D RNP complex small-subunit processome ribosome biogenesis snoRNA localization ATPase binding pre-snoRNP complex |
03008 |
| TC1900000683.mm.2 |
Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
19 |
46075846 |
NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086 NM_001039351, NM_001039352, NM_001039353, NM_053086 |
70769 |
29 |
protein binding nucleus nucleoplasm nucleoplasm nucleolus nucleolus cytoplasm nucleolus organization Cajal body small nuclear ribonucleoprotein complex |
|
| TC0700001122.mm.2 |
Fanci |
Fanconi anemia, complementation group I |
7 |
79392337 |
NM_145946 |
208836 |
25 |
nucleus nucleoplasm cytoplasm cytosol DNA repair cellular response to DNA damage stimulus cell cycle positive regulation of protein ubiquitination Fanconi anaemia nuclear complex DNA polymerase binding DNA polymerase binding |
|
| TC1000000636.mm.2 |
Egr2 |
early growth response 2 |
10 |
67537868, 67537929, 67537565, 67537210, 67535498, 67537869 |
NM_010118, BC009093 NM_010118, BC009093 |
13654 |
484 |
transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II activating transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific nucleic acid binding DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II protein export from nucleus rhythmic behavior rhythmic behavior motor neuron axon guidance gene expression Schwann cell differentiation positive regulation of Schwann cell differentiation transferase activity protein sumoylation rhombomere 3 development facial nerve structural organization facial nerve structural organization rhombomere 3 structural organization rhombomere 3 formation rhombomere 5 structural organization rhombomere 5 structural organization rhombomere 5 formation regulation of ossification ubiquitin protein ligase binding positive regulation of myelination response to insulin brain segmentation skeletal muscle cell differentiation myelination intracellular membrane-bounded organelle sequence-specific DNA binding sequence-specific DNA binding fat cell differentiation positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding SUMO ligase activity cellular response to organic substance HMG box domain binding sequence-specific double-stranded DNA binding |
|
| TC0200000432.mm.2 |
Bmyc |
brain expressed myelocytomatosis oncogene |
2 |
25706878 |
NM_023326, BC056436, BC060207, BC061001 NM_023326, BC056436, BC060207, BC061001 NM_023326, BC056436, BC060207, BC061001 NM_023326, BC056436, BC060207, BC061001 |
107771 |
31 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity protein binding nucleus spindle regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II positive regulation of cell population proliferation |
|
| TC0100003505.mm.2 |
Hsd17b7 |
hydroxysteroid (17-beta) dehydrogenase 7 |
1 |
-169949536 |
NM_010476 |
15490 |
38 |
3-keto sterol reductase activity 3-keto sterol reductase activity 3-keto sterol reductase activity estradiol 17-beta-dehydrogenase activity estradiol 17-beta-dehydrogenase activity prolactin receptor binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process estrogen biosynthetic process estrogen biosynthetic process nervous system development brain development androgen metabolic process androgen metabolic process membrane integral component of membrane oxidoreductase activity cell differentiation 5alpha-androstane-3beta,17beta-diol dehydrogenase activity 5alpha-androstane-3beta,17beta-diol dehydrogenase activity embryonic organ development embryonic skeletal system development |
00100 00140 01100 |
| TC0300002352.mm.2 |
Cks1b |
CDC28 protein kinase 1b |
3 |
-89415471 |
NM_016904, BC076579 NM_016904, BC076579 |
54124 |
38 |
cyclin-dependent protein kinase holoenzyme complex regulation of transcription, DNA-templated cell cycle regulation of mitotic cell cycle cell population proliferation embryo development cyclin-dependent protein serine/threonine kinase regulator activity SCF ubiquitin ligase complex protein kinase binding histone binding ubiquitin binding mitotic cell cycle phase transition cell division cyclin-dependent protein serine/threonine kinase activator activity |
05200 05222 |
| TC1300001630.mm.2 |
H2bc9 |
H2B clustered histone 9 |
13 |
-23542922 |
NM_178197, BC092138, BC132584, BC132586 NM_178197, BC092138, BC132584, BC132586 NM_178197, BC092138, BC132584, BC132586 NM_178197, BC092138, BC132584, BC132586 |
319182 |
16 |
nucleosome DNA binding nucleus nucleoplasm chromosome nucleosome assembly protein heterodimerization activity |
05322 |
| TC0700003743.mm.2 |
Ddias |
DNA damage-induced apoptosis suppressor |
7 |
-92857525 |
NM_001080995, BC066148 NM_001080995, BC066148 |
74041 |
18 |
molecular_function nucleus nucleus cytoplasm cytoplasm apoptotic process cellular response to DNA damage stimulus cell cycle cell cycle arrest spermatid development hemopoiesis cellular response to UV cellular response to cytokine stimulus cellular response to hydroperoxide cellular response to gamma radiation mitotic cell cycle arrest mitotic cell cycle arrest regulation of DNA stability negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of fibroblast apoptotic process |
|
| TC0200005378.mm.2 |
Gm14326 |
predicted gene 14326 |
2 |
-177944590, -177935992 |
NM_001190302, NM_001282028 NM_001190302, NM_001282028 |
665211 |
9 |
molecular_function cellular_component biological_process |
|
| TC0100000642.mm.2 |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
1 |
74713534 |
NM_024264, BC002183, BC055028 NM_024264, BC002183, BC055028 NM_024264, BC002183, BC055028 |
104086 |
69 |
monooxygenase activity iron ion binding mitochondrion mitochondrion mitochondrion mitochondrial envelope mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process steroid biosynthetic process bile acid biosynthetic process cholesterol catabolic process steroid metabolic process cholesterol metabolic process cholesterol metabolic process membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen heme binding vitamin D3 25-hydroxylase activity vitamin D3 25-hydroxylase activity Hsp70 protein binding cholesterol 26-hydroxylase activity cholesterol 26-hydroxylase activity calcitriol biosynthetic process from calciol calcitriol biosynthetic process from calciol metal ion binding cholestanetriol 26-monooxygenase activity |
00120 01100 03320 |
| TC0500001380.mm.2 |
Ppp1cc |
protein phosphatase 1 catalytic subunit gamma |
5 |
122158274 |
NM_013636, BC010613, BC021646, BC085496 NM_013636, BC010613, BC021646, BC085496 NM_013636, BC010613, BC021646, BC085496 NM_013636, BC010613, BC021646, BC085496 |
19047 |
109 |
protein phosphatase type 1 complex chromosome, centromeric region kinetochore phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein serine/threonine phosphatase activity protein serine/threonine phosphatase activity protein binding lamin binding nucleus chromosome cytoplasm cytoplasm mitochondrion mitochondrial outer membrane carbohydrate metabolic process glycogen metabolic process protein dephosphorylation protein dephosphorylation protein dephosphorylation cell cycle protein C-terminus binding protein phosphatase 1 binding hydrolase activity phosphatase activity protein phosphatase binding protein domain specific binding neuron differentiation circadian regulation of gene expression regulation of circadian rhythm regulation of circadian rhythm entrainment of circadian clock by photoperiod dendritic spine protein-containing complex binding regulation of nucleocytoplasmic transport metal ion binding protein N-terminus binding rhythmic process cell division positive regulation of glial cell proliferation presynapse postsynapse glutamatergic synapse |
04114 04270 04510 04720 04810 04910 |
| TC0600000324.mm.2 |
Akr1b8 |
aldo-keto reductase family 1, member B8 |
6 |
34354145 |
NM_008012, BC005789 NM_008012, BC005789 |
14187 |
23 |
retinoid metabolic process retinal dehydrogenase activity alditol:NADP+ 1-oxidoreductase activity cytoplasm mitochondrion cytosol alcohol dehydrogenase (NADP+) activity farnesol catabolic process oxidoreductase activity daunorubicin metabolic process doxorubicin metabolic process geranylgeranyl reductase activity indanol dehydrogenase activity NADP-retinol dehydrogenase activity cellular detoxification of aldehyde |
00040 00051 00052 00561 00620 01100 |
| TC0900001673.mm.2 |
Ccr3 |
chemokine (C-C motif) receptor 3 |
9 |
124021970 |
NM_009914, BC108967, BC108968 NM_009914, BC108967, BC108968 NM_009914, BC108967, BC108968 |
12771 |
76 |
positive regulation of endothelial cell proliferation mast cell chemotaxis G protein-coupled receptor activity chemokine receptor activity protein binding extracellular space cytoplasm endosome plasma membrane chemotaxis inflammatory response immune response signal transduction positive regulation of cytosolic calcium ion concentration external side of plasma membrane membrane integral component of membrane C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding C-C chemokine binding C-C chemokine binding angioblast cell migration positive regulation of angiogenesis positive regulation of angiogenesis eosinophil chemotaxis cell chemotaxis ERK1 and ERK2 cascade |
04060 04062 |
| TC1200002242.mm.2 |
Fbln5 |
fibulin 5 |
12 |
-101746564, -101746564 |
NM_011812, BC006636 NM_011812, BC006636 |
23876 |
75 |
negative regulation of transcription by RNA polymerase II integrin binding calcium ion binding protein binding extracellular region extracellular region extracellular space extracellular space cell adhesion protein C-terminus binding negative regulation of angiogenesis extracellular matrix constituent conferring elasticity extracellular matrix organization positive regulation of osteoblast proliferation protein localization to cell surface protein homodimerization activity positive regulation of transcription by RNA polymerase II secretion elastic fiber assembly elastic fiber assembly elastic fiber assembly collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix elastic fiber intramembranous bone growth regulation of removal of superoxide radicals |
|
| TC1900000763.mm.2 |
Pdcd4 |
programmed cell death 4 |
19 |
53903350, 53892230 |
NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739 NM_001168491, NM_001168492, NM_011050, BC055739 |
18569 |
88 |
RNA binding protein binding nucleus nucleus cytoplasm cytosol cytosol apoptotic process cell aging BMP signaling pathway positive regulation of smooth muscle cell apoptotic process negative regulation of apoptotic process negative regulation of transcription, DNA-templated positive regulation of inflammatory response regulation of protein metabolic process epithelial to mesenchymal transition involved in cardiac fibroblast development cellular response to lipopolysaccharide negative regulation of cytokine production involved in inflammatory response positive regulation of NIK/NF-kappaB signaling negative regulation of vascular associated smooth muscle cell proliferation negative regulation of myofibroblast differentiation negative regulation of vascular associated smooth muscle cell differentiation positive regulation of vascular associated smooth muscle cell apoptotic process positive regulation of endothelial cell apoptotic process |
|
| TC1300001955.mm.2 |
Susd3 |
sushi domain containing 3 |
13 |
-49230688, -49230688 |
NM_025491, NM_028340, BC045525 NM_025491, NM_028340, BC045525 NM_025491, NM_028340, BC045525 |
66329 |
17 |
molecular_function plasma membrane plasma membrane biological_process membrane integral component of membrane |
|
| TC0200003401.mm.2 |
Strbp |
spermatid perinuclear RNA binding protein |
2 |
-37569867, -37569867, -37569867, -37569867 |
NM_009261, BC014710 NM_009261, BC014710 |
20744 |
32 |
manchette RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding nucleus cytoplasm cytoskeleton movement of cell or subcellular component multicellular organism development spermatogenesis spermatid development mechanosensory behavior microtubule binding microtubule cytoskeleton tubulin binding cell differentiation |
|
| TC1200000719.mm.2 |
Rad51b |
RAD51 paralog B |
12 |
79297281, 79297350 |
NM_001252562, NM_009014, BC058184 NM_001252562, NM_009014, BC058184 NM_001252562, NM_009014, BC058184 |
19363 |
22 |
nucleotide binding four-way junction DNA binding four-way junction DNA binding double-strand break repair via homologous recombination double-strand break repair via homologous recombination in utero embryonic development in utero embryonic development blastocyst growth DNA binding double-stranded DNA binding double-stranded DNA binding single-stranded DNA binding single-stranded DNA binding ATP binding nucleus replication fork replication fork DNA repair DNA recombination cellular response to DNA damage stimulus DNA-dependent ATPase activity DNA-dependent ATPase activity positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle Rad51B-Rad51C-Rad51D-XRCC2 complex Rad51B-Rad51C-Rad51D-XRCC2 complex somite development |
03440 |
| TC0600002903.mm.2 |
Rad18 |
RAD18 E3 ubiquitin protein ligase |
6 |
-112619850, -112619870, -112628175 |
NM_001167730, NM_021385, BC011120 NM_001167730, NM_021385, BC011120 NM_001167730, NM_021385, BC011120 |
58186 |
41 |
Y-form DNA binding chromatin XY body DNA binding single-stranded DNA binding protein binding nucleus nucleus nucleus nucleoplasm replication fork cytoplasm centrosome cytoskeleton DNA repair postreplication repair protein monoubiquitination cellular response to DNA damage stimulus cellular response to DNA damage stimulus spermatogenesis response to UV response to UV nuclear body transferase activity polyubiquitin modification-dependent protein binding ubiquitin protein ligase binding site of double-strand break nuclear inclusion body identical protein binding protein-containing complex binding negative regulation of DNA recombination metal ion binding protein autoubiquitination positive regulation of chromosome segregation negative regulation of cell death ubiquitin protein ligase activity Rad6-Rad18 complex |
|
| TC0600002858.mm.2 |
Shq1 |
SHQ1 homolog (S. cerevisiae) |
6 |
-100571810 |
NM_181590, BC052657 NM_181590, BC052657 |
72171 |
18 |
box H/ACA snoRNP assembly nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytosol ribonucleoprotein complex assembly positive regulation of apoptotic process unfolded protein binding negative regulation of rRNA processing |
|
| TC0500003651.mm.2 |
Gm8615 |
glucosamine-6-phosphate deaminase 1 pseudogene |
5 |
-149154127 |
NR_028061 |
667410 |
1 |
|
|
| TC1400000578.mm.2 |
|
|
|
|
NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 NM_001161731, NM_007447, NM_021472, NM_201239, BC005569, BC055355, BC061105, BC066843 |
|
|
angiogenesis angiogenesis response to hypoxia response to yeast response to yeast positive regulation of endothelial cell proliferation nucleic acid binding DNA binding RNA binding actin binding nuclease activity endonuclease activity ribonuclease activity ribonuclease activity ribonuclease activity signaling receptor binding copper ion binding extracellular region extracellular region extracellular region basement membrane extracellular space extracellular space extracellular space nucleus chromosome nucleolus diacylglycerol biosynthetic process activation of phospholipase C activity multicellular organism development central nervous system development heparin binding cellular response to starvation rRNA transcription response to hormone actin cytoskeleton cell migration hydrolase activity negative regulation of translation antibacterial humoral response antibacterial humoral response antibacterial humoral response antifungal humoral response antifungal humoral response cell differentiation growth cone cytoplasmic vesicle activation of protein kinase B activity angiogenin-PRI complex activation of phospholipase A2 activity peptide binding positive regulation of phosphorylation protein homodimerization activity neuronal cell body innate immune response innate immune response innate immune response negative regulation of smooth muscle cell proliferation positive regulation of protein secretion defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide RNA phosphodiester bond hydrolysis |
|
| TC0X00003301.mm.2 |
Reps2 |
RALBP1 associated Eps domain containing protein 2 |
X |
-162411951, -162411951 |
NM_178256, BC139012, BC145500 NM_178256, BC139012, BC145500 NM_178256, BC139012, BC145500 |
194590 |
19 |
molecular_function calcium ion binding cytoplasm plasma membrane endocytosis endosomal transport metal ion binding |
|
| TC0900001908.mm.2 |
Anln |
anillin, actin binding protein |
9 |
-22331213 |
NM_028390, BC030489, BC032164 NM_028390, BC030489, BC032164 NM_028390, BC030489, BC032164 |
68743 |
47 |
mitotic cytokinesis mitotic cytokinesis actomyosin contractile ring assembly hematopoietic progenitor cell differentiation actin binding nucleus nucleoplasm cytoplasm actomyosin contractile ring actomyosin contractile ring cytoskeleton cell cycle actin cytoskeleton midbody septin ring organization bleb cell projection cell division glomerular visceral epithelial cell migration cell cortex region positive regulation of bleb assembly |
|
| TC0100002481.mm.2 |
Idh1 |
isocitrate dehydrogenase 1 (NADP+), soluble |
1 |
-65158615, -65158615 |
NM_001111320, NM_010497, BC088986 NM_001111320, NM_010497, BC088986 NM_001111320, NM_010497, BC088986 |
15926 |
147 |
magnesium ion binding isocitrate dehydrogenase activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity isocitrate dehydrogenase (NADP+) activity cytoplasm mitochondrion mitochondrion mitochondrion peroxisome peroxisome cytosol cytosol cytosol glyoxylate cycle tricarboxylic acid cycle isocitrate metabolic process isocitrate metabolic process 2-oxoglutarate metabolic process NADP metabolic process glutathione metabolic process response to oxidative stress response to organic cyclic compound oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor identical protein binding protein homodimerization activity metal ion binding response to steroid hormone NADP binding NAD binding regulation of phospholipid catabolic process regulation of phospholipid biosynthetic process |
00020 00480 01100 04146 |
| TC0600002741.mm.2 |
Mrps25 |
mitochondrial ribosomal protein S25 |
6 |
-92169522 |
NM_025578, BC022953 NM_025578, BC022953 |
64658 |
28 |
structural constituent of ribosome structural constituent of ribosome mitochondrion mitochondrion mitochondrion mitochondrial small ribosomal subunit ribosome mitochondrial translation |
|
| TC1100003693.mm.2 |
Top2a |
topoisomerase (DNA) II alpha |
11 |
-98992946 |
NM_011623 |
21973 |
101 |
nucleotide binding nuclear chromosome magnesium ion binding resolution of meiotic recombination intermediates chromosome, centromeric region condensed chromosome condensed chromosome sister chromatid segregation hematopoietic progenitor cell differentiation DNA binding chromatin binding DNA topoisomerase activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm nucleolus nucleolus cytoplasm centriole DNA metabolic process DNA topological change DNA topological change DNA ligation cellular response to DNA damage stimulus chromosome segregation chromosome segregation chromosome segregation female meiotic nuclear division protein C-terminus binding DNA-dependent ATPase activity DNA binding, bending DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex isomerase activity enzyme binding chromosome condensation apoptotic chromosome condensation apoptotic chromosome condensation protein-containing complex embryonic cleavage regulation of circadian rhythm protein homodimerization activity histone deacetylase binding positive regulation of apoptotic process ubiquitin binding sequence-specific DNA binding positive regulation of single stranded viral RNA replication via double stranded DNA intermediate positive regulation of transcription by RNA polymerase II metal ion binding protein heterodimerization activity rhythmic process female meiosis chromosome separation negative regulation of DNA duplex unwinding ribonucleoprotein complex |
|
| TC0700000989.mm.2 |
Snrpa1 |
small nuclear ribonucleoprotein polypeptide A' |
7 |
66060335 |
NM_021336, BC013777, BC029642 NM_021336, BC013777, BC029642 NM_021336, BC013777, BC029642 |
68981 |
24 |
mRNA splicing, via spliceosome mRNA splicing, via spliceosome RNA binding nucleus nucleoplasm spliceosomal complex U2 snRNP U2 snRNP mRNA processing spermatogenesis RNA splicing nuclear body nuclear speck U2 snRNA binding U2-type precatalytic spliceosome U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome |
03040 |
| TC1000000312.mm.2 |
Hdac2 |
histone deacetylase 2 |
10 |
36974543 |
NM_008229, BC138517 NM_008229, BC138517 |
15182 |
299 |
histone deacetylase complex histone deacetylase complex negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin heterochromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II repressing transcription factor binding RNA polymerase II transcription corepressor binding chromatin binding histone deacetylase activity histone deacetylase activity histone deacetylase activity histone deacetylase activity protein binding nucleus nucleus nucleoplasm nucleoplasm replication fork transcription regulator complex cytoplasm cytoplasm chromatin organization protein deacetylation transcription factor binding transcription factor binding positive regulation of cell population proliferation positive regulation of cell population proliferation epidermal cell differentiation positive regulation of epithelial to mesenchymal transition negative regulation of neuron projection development negative regulation of neuron projection development dendrite development histone deacetylation histone deacetylation Sin3 complex NuRD complex hydrolase activity transcription repressor complex deacetylase activity deacetylase activity enzyme binding enzyme binding hippocampus development neuron differentiation heat shock protein binding chromatin DNA binding NAD-dependent histone deacetylase activity (H3-K14 specific) positive regulation of interleukin-1 production positive regulation of tumor necrosis factor production circadian regulation of gene expression protein-containing complex protein deacetylase activity protein deacetylase activity histone deacetylase activity (H4-K16 specific) ESC/E(Z) complex Krueppel-associated box domain binding cellular response to trichostatin A odontogenesis of dentin-containing tooth positive regulation of tyrosine phosphorylation of STAT protein embryonic digit morphogenesis histone deacetylase binding negative regulation of apoptotic process negative regulation of DNA binding negative regulation of DNA-binding transcription factor activity sequence-specific DNA binding positive regulation of proteolysis negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II rhythmic process positive regulation of oligodendrocyte differentiation positive regulation of oligodendrocyte differentiation NF-kappaB binding positive regulation of DNA-binding transcription factor activity regulation of protein kinase B signaling cardiac muscle cell development negative regulation of cardiac muscle cell proliferation regulation of sarcomere organization hair follicle placode formation negative regulation of dendritic spine development eyelid development in camera-type eye fungiform papilla formation cellular response to hydrogen peroxide histone H3-K27 methylation heterochromatin maintenance histone H3 deacetylation histone H3 deacetylation histone H3 deacetylation histone H4 deacetylation histone H4 deacetylation negative regulation of canonical Wnt signaling pathway regulation of protein deacetylation RNA polymerase II transcription repressor complex positive regulation of male mating behavior negative regulation of pri-miRNA transcription by RNA polymerase II negative regulation of pri-miRNA transcription by RNA polymerase II promoter-specific chromatin binding positive regulation of signaling receptor activity negative regulation of peptidyl-lysine acetylation negative regulation of intrinsic apoptotic signaling pathway |
04110 04330 05016 05200 05220 |
| TC1900001116.mm.2 |
Tmem109 |
transmembrane protein 109 |
19 |
-10870660 |
NM_134142, BC022997, BC023901, BC025033, BC025815 NM_134142, BC022997, BC023901, BC025033, BC025815 NM_134142, BC022997, BC023901, BC025033, BC025815 NM_134142, BC022997, BC023901, BC025033, BC025815 NM_134142, BC022997, BC023901, BC025033, BC025815 |
68539 |
27 |
voltage-gated ion channel activity protein binding nucleus endoplasmic reticulum ion transport membrane integral component of membrane sarcoplasmic reticulum nuclear membrane regulation of ion transmembrane transport intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of cell death negative regulation of cell death cellular response to gamma radiation cellular response to gamma radiation |
|
| TC1700001192.mm.2 |
Ndufaf7 |
NADH:ubiquinone oxidoreductase complex assembly factor 7 |
17 |
78937134 |
NM_028611, BC108350 NM_028611, BC108350 |
73694 |
19 |
mitochondrion mitochondrion mitochondrion methyltransferase activity transferase activity enzyme binding peptidyl-arginine methylation, to symmetrical-dimethyl arginine methylation mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex I assembly protein-arginine omega-N symmetric methyltransferase activity protein-arginine omega-N symmetric methyltransferase activity |
|
| TC0800003059.mm.2 |
Slc7a5 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 |
8 |
-121881145 |
NM_011404, BC026131 NM_011404, BC026131 |
20539 |
56 |
amino acid transmembrane transport lysosome cytosol plasma membrane amino acid transport basal plasma membrane negative regulation of gene expression amino acid transmembrane transporter activity aromatic amino acid transmembrane transporter activity neutral amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity L-leucine transmembrane transporter activity L-tryptophan transmembrane transporter activity thyroid hormone transmembrane transporter activity L-amino acid transport phenylalanine transport membrane integral component of membrane basolateral plasma membrane apical plasma membrane transmembrane transporter activity microvillus membrane positive regulation of interferon-gamma production positive regulation of interleukin-17 production positive regulation of interleukin-4 production xenobiotic transport intracellular membrane-bounded organelle transmembrane transport thyroid hormone transport amino acid import across plasma membrane external side of apical plasma membrane leucine import across plasma membrane L-leucine import across plasma membrane L-tryptophan transmembrane transport amino acid transport complex |
|
| TC0800001639.mm.2 |
Shcbp1 |
Shc SH2-domain binding protein 1 |
8 |
-4735975 |
NM_011369, BC070455 NM_011369, BC070455 |
20419 |
24 |
protein binding cellular_component cytoplasm cytoskeleton fibroblast growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway SH2 domain binding regulation of neural precursor cell proliferation |
|
| TC0800002869.mm.2 |
|
|
|
|
NM_026513, NM_139229, BC094654 NM_026513, NM_139229, BC094654 NM_026513, NM_139229, BC094654 |
|
|
molecular_function mitochondrion mitochondrion Golgi apparatus intra-Golgi vesicle-mediated transport positive regulation of cell population proliferation protein transport membrane Golgi transport complex Golgi transport complex peptidyl-methionine modification peptidyl-methionine modification N-terminal protein amino acid modification N-terminal protein amino acid modification peptide deformylase activity peptide deformylase activity co-translational protein modification |
|
| TC0300003113.mm.2 |
Adgrl2 |
adhesion G protein-coupled receptor L2 |
3 |
-148815585 |
NM_001081298, BC172691 NM_001081298, BC172691 |
99633 |
26 |
transmembrane signaling receptor activity G protein-coupled receptor activity integral component of plasma membrane signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway brain development response to bacterium membrane integral component of membrane PDZ domain binding carbohydrate binding neuron projection neuron projection synapse organization synapse organization positive regulation of synapse assembly glutamatergic synapse glutamatergic synapse integral component of postsynaptic membrane integral component of postsynaptic membrane |
|
| TC0100000447.mm.2 |
Cdk15 |
cyclin-dependent kinase 15 |
1 |
59256905 |
NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 NM_001033373, BC147314, BC147315, BC147758, BC147763, BC172036 |
271697 |
15 |
regulation of transcription involved in G1/S transition of mitotic cell cycle nucleotide binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytosol protein phosphorylation kinase activity phosphorylation transferase activity cyclin binding metal ion binding |
|
| TC0100002965.mm.2 |
Steap3 |
STEAP family member 3 |
1 |
-120226413, -120226413, -120226413, -120226413 |
NM_001085409, NM_133186, BC037435 NM_001085409, NM_133186, BC037435 NM_001085409, NM_133186, BC037435 |
68428 |
33 |
ferric-chelate reductase activity ferric-chelate reductase activity protein binding cytoplasm endosome endosome multivesicular body plasma membrane plasma membrane ion transport iron ion transport apoptotic process cell cycle cupric reductase activity cupric reductase activity protein secretion protein secretion copper ion import copper ion import copper ion import membrane integral component of membrane oxidoreductase activity iron import into cell identical protein binding positive regulation of apoptotic process metal ion binding ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity iron ion homeostasis iron ion import across cell outer membrane iron ion import across cell outer membrane positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator exosomal secretion |
04115 |
| TC1500000785.mm.2 |
Parvb |
parvin, beta |
15 |
84232042 |
NM_133167, BC138747, BC138748, BC158113 NM_133167, BC138747, BC138748, BC158113 NM_133167, BC138747, BC138748, BC158113 NM_133167, BC138747, BC138748, BC158113 |
170736 |
39 |
actin binding protein binding cytoplasm cytoskeleton plasma membrane focal adhesion focal adhesion cell adhesion establishment or maintenance of cell polarity actin cytoskeleton membrane lamellipodium lamellipodium cell projection assembly cell projection assembly lamellipodium assembly lamellipodium assembly cell junction actin cytoskeleton reorganization actin cytoskeleton reorganization substrate adhesion-dependent cell spreading cell projection establishment or maintenance of cell polarity regulating cell shape |
04510 |
| TC0800001541.mm.2 |
Urb2 |
URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
8 |
124021496 |
NM_001029876, BC151125 NM_001029876, BC151125 |
382038 |
13 |
molecular_function nucleolus nucleolus aggresome midbody ribosome biogenesis |
|
| TC1500001933.mm.2 |
Polr3h |
polymerase (RNA) III (DNA directed) polypeptide H |
15 |
-81915029 |
NM_030229, BC010793 NM_030229, BC010793 |
78929 |
23 |
immune system process DNA binding DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex centrosome nucleobase-containing compound metabolic process transcription, DNA-templated transcription by RNA polymerase III transcription initiation from RNA polymerase III promoter intracellular membrane-bounded organelle innate immune response defense response to virus |
00230 00240 01100 03020 04623 |
| TC0200000391.mm.2 |
Zmynd19 |
zinc finger, MYND domain containing 19 |
2 |
24949776, 24950157 |
NM_026021, BC027321 NM_026021, BC027321 |
67187 |
26 |
molecular_function cytoplasm plasma membrane biological_process membrane synapse metal ion binding |
|
| TC0X00002165.mm.2 |
Aifm1 |
apoptosis-inducing factor, mitochondrion-associated 1 |
X |
-48474943 |
NM_012019, BC003292 NM_012019, BC003292 |
26926 |
149 |
DNA binding DNA binding electron-transferring-flavoprotein dehydrogenase activity protein binding nucleus nucleus nucleus cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane mitochondrial intermembrane space mitochondrial intermembrane space cytosol cytosol cytosol apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process response to oxidative stress apoptotic mitochondrial changes positive regulation of cell death membrane NAD(P)H oxidase H2O2-forming activity NAD(P)H oxidase H2O2-forming activity oxidoreductase activity oxidoreductase activity, acting on NAD(P)H neuron differentiation mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex assembly mitochondrial respiratory chain complex assembly positive regulation of apoptotic process positive regulation of neuron apoptotic process protein import into mitochondrial intermembrane space protein import into mitochondrial intermembrane space protein dimerization activity flavin adenine dinucleotide binding neuron apoptotic process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress FAD binding FAD binding regulation of apoptotic DNA fragmentation |
04210 |
| TC0100001711.mm.2 |
|
|
|
|
NM_007415, NR_105869, BC012041 NM_007415, NR_105869, BC012041 NM_007415, NR_105869, BC012041 |
|
|
telomere maintenance DNA binding chromatin binding NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity protein binding nucleus nucleus nucleus nuclear envelope nucleoplasm nucleoplasm transcription regulator complex chromosome nucleolus nucleolus nucleolus cytoplasm cytoplasm mitochondrion DNA metabolic process DNA repair base-excision repair double-strand break repair double-strand break repair double-strand break repair protein ADP-ribosylation apoptotic process cellular response to DNA damage stimulus mitochondrion organization mitochondrion organization transforming growth factor beta receptor signaling pathway transcription factor binding zinc ion binding positive regulation of cardiac muscle hypertrophy regulation of SMAD protein complex assembly protein autoprocessing nuclear body transferase activity transferase activity, transferring glycosyl groups peptidyl-serine ADP-ribosylation peptidyl-glutamic acid poly-ADP-ribosylation enzyme binding protein kinase binding signal transduction involved in regulation of gene expression estrogen receptor binding DNA ADP-ribosylation mitochondrial DNA metabolic process negative regulation of interleukin-17 production cellular response to insulin stimulus protein-containing complex protein-containing complex protein-DNA complex positive regulation of intracellular estrogen receptor signaling pathway cellular response to oxidative stress cellular response to UV site of double-strand break protein modification process regulation of growth rate DNA damage response, detection of DNA damage identical protein binding histone deacetylase binding mitochondrial DNA repair regulation of DNA methylation positive regulation of transcription by RNA polymerase II SMAD binding metal ion binding protein N-terminus binding behavioral response to cocaine regulation of catalytic activity voluntary musculoskeletal movement NAD binding positive regulation of mitochondrial depolarization positive regulation of SMAD protein signal transduction protein poly-ADP-ribosylation protein poly-ADP-ribosylation protein poly-ADP-ribosylation protein auto-ADP-ribosylation R-SMAD binding cellular response to superoxide cellular response to transforming growth factor beta stimulus site of DNA damage NAD DNA ADP-ribosyltransferase activity positive regulation of protein localization to nucleus positive regulation of neuron death regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway regulation of single strand break repair positive regulation of single strand break repair positive regulation of single strand break repair regulation of cellular protein localization negative regulation of telomere maintenance via telomere lengthening cellular response to amyloid-beta positive regulation of myofibroblast differentiation positive regulation of double-strand break repair via homologous recombination protein ADP-ribosylase activity protein ADP-ribosylase activity protein ADP-ribosylase activity ATP generation from poly-ADP-D-ribose positive regulation of transcription regulatory region DNA binding negative regulation of ATP biosynthetic process |
|
| TC0100001855.mm.2 |
Lpgat1 |
lysophosphatidylglycerol acyltransferase 1 |
1 |
191718023, 191718394 |
NM_001134829, NM_172266, BC013667 NM_001134829, NM_172266, BC013667 NM_001134829, NM_172266, BC013667 |
226856 |
17 |
2-acylglycerol O-acyltransferase activity cytoplasm endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process phospholipid biosynthetic process endomembrane system membrane integral component of membrane transferase activity transferase activity, transferring acyl groups triglyceride biosynthetic process phosphatidylinositol acyl-chain remodeling positive regulation of fatty acid biosynthetic process lysophospholipid acyltransferase activity |
00564 |
| TC1900000216.mm.2 |
|
|
|
|
XM_986941 |
|
|
|
|
| TC1500001742.mm.2 |
Top1mt |
DNA topoisomerase 1, mitochondrial |
15 |
-75657032 |
NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336 NM_028404, BC138582, BC138583, BC145336 |
72960 |
21 |
DNA binding DNA topoisomerase activity DNA topoisomerase type I (single strand cut, ATP-independent) activity nucleoplasm chromosome mitochondrion mitochondrion DNA replication DNA topological change isomerase activity mitochondrial nucleoid mitochondrial nucleoid |
|
| TC1400002621.mm.2 |
Tbc1d4 |
TBC1 domain family, member 4 |
14 |
-101442359 |
NM_001081278, BC117869, BC117870 NM_001081278, BC117869, BC117870 NM_001081278, BC117869, BC117870 |
210789 |
73 |
GTPase activator activity protein binding cytoplasm cytosol intracellular protein transport vesicle-mediated transport cytoplasmic vesicle membrane negative regulation of vesicle fusion vesicle cellular response to insulin stimulus activation of GTPase activity |
|
| TC0700002102.mm.2 |
Dhcr7 |
7-dehydrocholesterol reductase |
7 |
143830213, 143823166, 143823398 |
NM_007856, BC006854 NM_007856, BC006854 |
13360 |
56 |
blood vessel development nuclear outer membrane endoplasmic reticulum lipid metabolic process steroid biosynthetic process cholesterol biosynthetic process cholesterol biosynthetic process steroid metabolic process cholesterol metabolic process post-embryonic development sterol delta7 reductase activity membrane integral component of membrane sterol biosynthetic process sterol biosynthetic process brassinosteroid biosynthetic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor cell differentiation integral component of endoplasmic reticulum membrane lung development multicellular organism growth regulation of cell population proliferation intracellular membrane-bounded organelle regulation of cholesterol biosynthetic process 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity 7-dehydrocholesterol reductase activity |
00100 01100 |
| TC1000002175.mm.2 |
Man1a |
mannosidase 1, alpha |
10 |
-53904784 |
NM_008548, BC015265 NM_008548, BC015265 |
17155 |
30 |
Golgi membrane Golgi membrane catalytic activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus cytosol N-glycan processing metabolic process membrane integral component of membrane hydrolase activity hydrolase activity, acting on glycosyl bonds ubiquitin-dependent ERAD pathway cytoplasmic vesicle protein targeting to ER metal ion binding mannose trimming involved in glycoprotein ERAD pathway |
00510 01100 04141 |
| TC0500000971.mm.2 |
Enoph1 |
enolase-phosphatase 1 |
5 |
100039993 |
NM_001163035, NM_026421, NR_027990, BC021429 NM_001163035, NM_026421, NR_027990, BC021429 NM_001163035, NM_026421, NR_027990, BC021429 NM_001163035, NM_026421, NR_027990, BC021429 |
67870 |
26 |
magnesium ion binding nucleus cytoplasm cellular amino acid biosynthetic process methionine biosynthetic process hydrolase activity L-methionine salvage from methylthioadenosine L-methionine salvage from methylthioadenosine acireductone synthase activity acireductone synthase activity metal ion binding |
00270 |
| TC1500000736.mm.2 |
Xrcc6 |
X-ray repair complementing defective repair in Chinese hamster cells 6 |
15 |
82016368 |
NM_010247, BC031422 NM_010247, BC031422 |
14375 |
137 |
nucleotide binding telomere maintenance transcription regulatory region sequence-specific DNA binding activation of innate immune response immune system process DNA binding DNA helicase activity damaged DNA binding double-stranded DNA binding double-stranded DNA binding double-stranded DNA binding double-stranded telomeric DNA binding catalytic activity helicase activity protein binding ATP binding nucleus nucleus nucleoplasm transcription regulator complex chromosome nucleolus cytoplasm cytoplasm DNA repair double-strand break repair double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining DNA recombination cellular response to DNA damage stimulus protein C-terminus binding DNA-dependent ATPase activity metabolic process response to ionizing radiation hydrolase activity lyase activity cyclin binding protein-containing complex protein-DNA complex V(D)J recombination telomeric DNA binding Ku70:Ku80 complex Ku70:Ku80 complex protein-containing complex binding DNA end binding innate immune response positive regulation of lymphocyte differentiation positive regulation of protein kinase activity negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II regulation of smooth muscle cell proliferation positive regulation of neurogenesis 5'-deoxyribose-5-phosphate lyase activity nonhomologous end joining complex cellular hyperosmotic salinity response cellular response to gamma radiation cellular response to gamma radiation cellular response to X-ray cellular response to X-ray double-strand break repair via classical nonhomologous end joining |
03450 |
| MG-1-pos-10338344_st |
|
|
|
|
|
|
|
|
|
| MG-1-pos-10343581_st |
|
|
|
|
|
|
|
|
|
| TC0100003416.mm.2 |
BC055324 |
cDNA sequence BC055324 |
1 |
-163954005, -163945992 |
NM_201364, BC052855, BC055324 NM_201364, BC052855, BC055324 NM_201364, BC052855, BC055324 |
381306 |
15 |
molecular_function cellular_component biological_process |
|
| TC0900002942.mm.2 |
Pccb |
propionyl Coenzyme A carboxylase, beta polypeptide |
9 |
-100982031 |
NM_025835, BC037082, BC055946 NM_025835, BC037082, BC055946 NM_025835, BC037082, BC055946 |
66904 |
20 |
nucleotide binding propionyl-CoA carboxylase activity propionyl-CoA carboxylase activity ATP binding mitochondrion mitochondrial matrix ligase activity |
00280 00630 00640 01100 |
| TC1400002863.mm.2 |
Ipo4 |
importin 4 |
14 |
-55625399 |
NM_024267, BC003469, BC085150 NM_024267, BC003469, BC085150 NM_024267, BC003469, BC085150 |
75751 |
25 |
chromatin protein binding nucleus cytoplasm DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein import into nucleus protein import into nucleus intracellular protein transport nuclear localization sequence binding protein transport small GTPase binding protein-containing complex ribosome biogenesis nuclear import signal receptor activity |
|
| TC0700001951.mm.2 |
Dock1 |
dedicator of cytokinesis 1 |
7 |
134670686 |
NM_001033420 |
330662 |
46 |
hematopoietic progenitor cell differentiation guanyl-nucleotide exchange factor activity GTPase activator activity protein binding nucleoplasm cytoplasm cytosol phagocytosis apoptotic process cytoskeleton organization small GTPase mediated signal transduction positive regulation of epithelial cell migration membrane cell migration nuclear speck SH3 domain binding guanyl-nucleotide exchange factor complex positive regulation of substrate adhesion-dependent cell spreading |
04510 04810 05100 |
| TC0700000289.mm.2 |
Snrpd2 |
small nuclear ribonucleoprotein D2 |
7 |
19149837 |
NM_026943, BC043014, BC051208, BC116858, BC116860 NM_026943, BC043014, BC051208, BC116858, BC116860 NM_026943, BC043014, BC051208, BC116858, BC116860 NM_026943, BC043014, BC051208, BC116858, BC116860 NM_026943, BC043014, BC051208, BC116858, BC116860 |
107686 |
30 |
spliceosomal snRNP assembly spliceosomal snRNP assembly mRNA splicing, via spliceosome nucleus spliceosomal complex U5 snRNP U1 snRNP U1 snRNP U2 snRNP U4 snRNP U12-type spliceosomal complex cytoplasm cytosol mRNA processing RNA splicing small nuclear ribonucleoprotein complex methylosome pICln-Sm protein complex SMN-Sm protein complex U4/U6 x U5 tri-snRNP complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome U2-type catalytic step 2 spliceosome precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome U1 snRNP binding |
03040 |
| TC0100000297.mm.2 |
Il1rl2 |
interleukin 1 receptor-like 2 |
1 |
40324588 |
NM_133193, BC117797 NM_133193, BC117797 |
107527 |
33 |
immune system process cytokine receptor activity interleukin-1 receptor activity interleukin-1, type I, activating receptor activity cellular_component inflammatory response signal transduction membrane integral component of membrane hydrolase activity positive regulation of interleukin-6 production innate immune response positive regulation of T cell differentiation NAD(P)+ nucleosidase activity regulation of inflammatory response regulation of inflammatory response NAD+ nucleotidase, cyclic ADP-ribose generating |
|
| TC1100000475.mm.2 |
Havcr2 |
hepatitis A virus cellular receptor 2 |
11 |
46454930 |
NM_134250, BC106851, BC106852 NM_134250, BC106851, BC106852 NM_134250, BC106851, BC106852 |
171285 |
137 |
immunological synapse positive regulation of cytokine production adaptive immune response macrophage activation involved in immune response immune system process natural killer cell tolerance induction regulation of tolerance induction dependent upon immune response negative regulation of T-helper 1 type immune response negative regulation of immune response to tumor cell negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target protein binding extracellular region early endosome plasma membrane inflammatory response cell surface cell surface negative regulation of gene expression membrane integral component of membrane cell junction negative regulation of myeloid dendritic cell activation negative regulation of NF-kappaB transcription factor activity negative regulation of type I interferon production negative regulation of interferon-alpha production negative regulation of interferon-gamma production negative regulation of interferon-gamma production negative regulation of interleukin-2 production negative regulation of interleukin-2 production negative regulation of interleukin-3 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of interferon-gamma production positive regulation of interleukin-1 production positive regulation of interleukin-4 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production negative regulation of natural killer cell activation toll-like receptor 3 signaling pathway toll-like receptor 7 signaling pathway toll-like receptor 9 signaling pathway positive regulation of T cell proliferation negative regulation of T cell proliferation positive regulation of macrophage activation innate immune response positive regulation of innate immune response negative regulation of innate immune response metal ion binding defense response to Gram-positive bacterium maternal process involved in female pregnancy maternal process involved in female pregnancy positive regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide negative regulation of granulocyte colony-stimulating factor production negative regulation of defense response to bacterium positive regulation of defense response to bacterium positive regulation of NIK/NF-kappaB signaling negative regulation of immunological synapse formation negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell |
|
| TC0600001400.mm.2 |
Clec4b1 |
C-type lectin domain family 4, member b1 |
6 |
123049961 |
NM_001190310, NM_027218, BC146521 NM_001190310, NM_027218, BC146521 NM_001190310, NM_027218, BC146521 |
69810 |
15 |
positive regulation of release of sequestered calcium ion into cytosol |
|
| TC1100002102.mm.2 |
Slc35e4 |
solute carrier family 35, member E4 |
11 |
-3907021 |
NM_153142, BC020181 NM_153142, BC020181 |
103710 |
13 |
Golgi apparatus antiporter activity membrane integral component of membrane |
|
| TC0100000471.mm.2 |
Abi2 |
abl interactor 2 |
1 |
60409618 |
NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 NM_001198570, NM_001198571, NM_198127, BC056345, BC079545, BC079646 |
329165 |
33 |
cytoplasm cytosol cytoskeleton actin filament adherens junction adherens junction nervous system development learning or memory actin polymerization or depolymerization positive regulation of lamellipodium assembly dendrite development cell migration Rac protein signal transduction SH3 domain binding SH3 domain binding peptidyl-tyrosine phosphorylation lamellipodium lamellipodium cell junction dendrite SCAR complex small GTPase binding ubiquitin protein ligase binding filopodium tip signaling adaptor activity identical protein binding cell projection camera-type eye development dendritic spine zonula adherens assembly synapse regulation of dendritic spine morphogenesis proline-rich region binding lens fiber cell morphogenesis postsynaptic actin cytoskeleton postsynaptic actin cytoskeleton postsynaptic actin cytoskeleton organization postsynaptic actin cytoskeleton organization glutamatergic synapse glutamatergic synapse positive regulation of Arp2/3 complex-mediated actin nucleation |
04810 |
| TC1100000053.mm.2 |
Nipsnap1 |
nipsnap homolog 1 |
11 |
4873950 |
NM_008698, BC010837 NM_008698, BC010837 |
18082 |
28 |
protein binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane membrane sensory perception of pain sensory perception of pain neurotransmitter binding synaptic membrane |
|
| TC1300000247.mm.2 |
H3c7 |
H3 clustered histone 7 |
13 |
23544051 |
NM_013548, BC101954, BC101955, BC101956, BC103549 NM_013548, BC101954, BC101955, BC101956, BC103549 NM_013548, BC101954, BC101955, BC101956, BC103549 NM_013548, BC101954, BC101955, BC101956, BC103549 NM_013548, BC101954, BC101955, BC101956, BC103549 |
260423 |
55 |
nucleosome nucleus nucleus nucleosome assembly |
05322 |
| TC1300001645.mm.2 |
H4c1 |
H4 clustered histone 1 |
13 |
-23760794 |
NM_178192, BC119241, BC119243 NM_178192, BC119241, BC119243 NM_178192, BC119241, BC119243 |
326619 |
25 |
nuclear chromosome nucleosome nucleus nucleosome assembly DNA replication-dependent nucleosome assembly DNA replication-independent nucleosome assembly protein domain specific binding protein-containing complex negative regulation of megakaryocyte differentiation |
05322 |
| TC0800001917.mm.2 |
Ddhd2 |
DDHD domain containing 2 |
8 |
-25725323, -25725323 |
NM_028102, BC118962 NM_028102, BC118962 |
72108 |
22 |
phospholipase activity triglyceride lipase activity triglyceride lipase activity triglyceride lipase activity cytoplasm Golgi apparatus cytosol lipid metabolic process locomotory behavior visual learning membrane membrane lipid catabolic process hydrolase activity triglyceride catabolic process COPII-coated ER to Golgi transport vesicle lipid droplet organization centriolar satellite metal ion binding positive regulation of mitochondrial fission |
|
| TC0X00003371.mm.2 |
Msl3 |
MSL complex subunit 3 |
X |
-168651266, -168651266 |
NM_010832, BC010226 NM_010832, BC010226 |
17692 |
22 |
histone acetyltransferase complex DNA binding nucleus chromatin organization chromatin silencing regulation of transcription, DNA-templated histone acetylation histone deacetylation methylated histone binding NuA4 histone acetyltransferase complex histone H4 acetylation histone H2A acetylation histone H4-K16 acetylation histone H4-K16 acetylation histone acetyltransferase activity (H4-K16 specific) MSL complex MSL complex |
|
| TC0400002549.mm.2 |
Gne |
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
4 |
-44034074, -44034074 |
NM_001190414, NM_015828, BC015277, BC051254 NM_001190414, NM_015828, BC015277, BC051254 NM_001190414, NM_015828, BC015277, BC051254 NM_001190414, NM_015828, BC015277, BC051254 |
50798 |
49 |
nucleotide binding catalytic activity hydrolase activity, hydrolyzing O-glycosyl compounds ATP binding cytoplasm cytosol UDP-N-acetylglucosamine metabolic process N-acetylneuraminate metabolic process metabolic process UDP-N-acetylglucosamine 2-epimerase activity UDP-N-acetylglucosamine 2-epimerase activity N-acylmannosamine kinase activity N-acylmannosamine kinase activity kinase activity phosphorylation transferase activity hydrolase activity metal ion binding |
00520 01100 |
| TC0300001047.mm.2 |
Bcas2 |
breast carcinoma amplified sequence 2 |
3 |
103171654 |
NM_026602, BC023382, BC037062 NM_026602, BC023382, BC037062 NM_026602, BC023382, BC037062 |
68183 |
25 |
mRNA splicing, via spliceosome Prp19 complex molecular_function nucleus DNA replication factor A complex spliceosomal complex centrosome mRNA processing RNA splicing nuclear speck U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome |
03040 |
| TC1000002727.mm.2 |
Mrpl42 |
mitochondrial ribosomal protein L42 |
10 |
-95480804 |
NM_026065, BC024337 NM_026065, BC024337 |
67270 |
20 |
mitochondrion mitochondrion mitochondrial large ribosomal subunit mitochondrial large ribosomal subunit mitochondrial small ribosomal subunit ribosome plasma membrane biological_process |
|
| TC1700002541.mm.2 |
Fam98a |
family with sequence similarity 98, member A |
17 |
-75537084, -75537085 |
NM_133747, BC004626 NM_133747, BC004626 |
72722 |
26 |
protein binding protein methylation protein methyltransferase activity positive regulation of cell population proliferation positive regulation of gene expression lysosome localization tRNA-splicing ligase complex positive regulation of ruffle assembly |
|
| TC1100000609.mm.2 |
Kif3a |
kinesin family member 3A |
11 |
53567368 |
NM_008443, BC052707 NM_008443, BC052707 |
16568 |
175 |
nucleotide binding in utero embryonic development kidney development heart looping cilium movement microtubule motor activity protein binding ATP binding cytoplasm centrosome centriole centriole cytosol cytoskeleton kinesin complex microtubule spindle microtubule cilium axoneme microtubule-based movement smoothened signaling pathway determination of left/right symmetry heart development microtubule binding microtubule binding anterograde axonal transport epidermis development anterior/posterior pattern specification dorsal/ventral pattern formation centriole-centriole cohesion protein transport microtubule cytoskeleton ATPase activity kinesin II complex kinesin II complex kinesin binding protein phosphatase binding dentate gyrus development dorsal/ventral neural tube patterning dorsal/ventral neural tube patterning neural tube development cell projection organization spectrin binding forebrain development small GTPase binding motile cilium photoreceptor connecting cilium microtubule anchoring at centrosome epidermal stem cell homeostasis cell projection neuron projection neuronal cell body motile cilium assembly protein-containing complex binding positive regulation of receptor-mediated endocytosis positive regulation of epithelial cell proliferation inner ear receptor cell stereocilium organization cilium assembly cilium assembly neural precursor cell proliferation positive regulation of intracellular protein transport ribbon synapse intraciliary transport particle B binding protein localization to cell junction axon cytoplasm positive regulation of axo-dendritic protein transport non-motile cilium assembly positive regulation of establishment or maintenance of cell polarity regulating cell shape |
|
| TC1300000330.mm.2 |
Mboat1 |
membrane bound O-acyltransferase domain containing 1 |
13 |
30136489 |
NM_153546, BC023845, BC024653 NM_153546, BC023845, BC024653 NM_153546, BC023845, BC024653 |
218121 |
18 |
endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process phospholipid biosynthetic process regulation of neuron projection development membrane integral component of membrane transferase activity transferase activity, transferring acyl groups lipid modification phosphatidylserine acyl-chain remodeling phosphatidylethanolamine acyl-chain remodeling 1-acylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltransferase activity 1-acylglycerophosphoethanolamine O-acyltransferase activity 1-acylglycerophosphoserine O-acyltransferase activity |
00561 00564 01100 |
| TC1400002524.mm.2 |
|
|
|
|
|
|
|
|
|
| TC0100002866.mm.2 |
Pam |
peptidylglycine alpha-amidating monooxygenase |
1 |
-97821093, -97821093 |
NM_013626, BC166013 NM_013626, BC166013 |
18484 |
51 |
peptide amidation long-chain fatty acid metabolic process catalytic activity monooxygenase activity peptidylglycine monooxygenase activity peptidylglycine monooxygenase activity peptidylglycine monooxygenase activity peptidylamidoglycolate lyase activity copper ion binding calcium ion binding extracellular region extracellular space trans-Golgi network cytosol plasma membrane integral component of plasma membrane regulation of transcription by RNA polymerase II peptide metabolic process peptide metabolic process metabolic process zinc ion binding response to pH toxin metabolic process cell surface response to zinc ion membrane integral component of membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen lyase activity protein amidation protein metabolic process protein kinase binding secretory granule secretory granule membrane cytoplasmic vesicle L-ascorbic acid binding regulation of actin cytoskeleton organization response to drug identical protein binding neuron projection neuronal cell body perikaryon metal ion binding perinuclear region of cytoplasm regulation of protein secretion fatty acid primary amide biosynthetic process |
|
| TC0200004366.mm.2 |
Arhgap11a |
Rho GTPase activating protein 11A |
2 |
-113831491 |
NM_181416, BC050875 NM_181416, BC050875 |
228482 |
18 |
GTPase activator activity signal transduction |
|
| TC0200001886.mm.2 |
Eid1 |
EP300 interacting inhibitor of differentiation 1 |
2 |
125673099 |
NM_025613, BC160331, EP300 NM_025613, BC160331, EP300 NM_025613, BC160331, EP300 |
58521 |
29 |
negative regulation of transcription by RNA polymerase II transcription corepressor activity transcription corepressor activity protein binding nucleus nucleoplasm nucleoplasm cytoplasm cell cycle cell differentiation histone acetyltransferase regulator activity histone acetyltransferase binding regulation of histone acetylation cytoplasmic ribonucleoprotein granule regulation of cell differentiation negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated |
|
| TC0300000714.mm.2 |
Iqgap3 |
IQ motif containing GTPase activating protein 3 |
3 |
88082050 |
NM_001033484, BC151102, BC172704 NM_001033484, BC151102, BC172704 NM_001033484, BC151102, BC172704 |
404710 |
20 |
G1/S transition of mitotic cell cycle activation of MAPK activity positive regulation of protein phosphorylation GTPase activator activity protein binding calmodulin binding calmodulin binding cytoplasm cytoplasm cell-cell junction Ras protein signal transduction regulation of cell size positive regulation of gene expression negative regulation of gene expression lateral plasma membrane small GTPase binding regulation of actin cytoskeleton organization positive regulation of mammary gland epithelial cell proliferation actin filament binding ERK1 and ERK2 cascade myosin VI light chain binding cellular response to organic substance |
04810 |
| TC1400002025.mm.2 |
Supt16 |
SPT16, facilitates chromatin remodeling subunit |
14 |
-52160418 |
NM_033618 |
114741 |
43 |
nucleus nucleoplasm chromosome DNA replication DNA repair transcription elongation from RNA polymerase II promoter cellular response to DNA damage stimulus nucleosome binding positive regulation of transcription elongation from RNA polymerase II promoter DNA replication-independent nucleosome organization FACT complex |
|
| TC0800001436.mm.2 |
6430548M08Rik |
RIKEN cDNA 6430548M08 gene |
8 |
120114151, 120114151, 120144928 |
NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 NM_001163760, NM_001163761, NM_001163762, NM_172286, BC027126 |
234797 |
15 |
molecular_function cellular_component biological_process |
|
| TC0X00002053.mm.2 |
Septin6 |
septin 6 |
X |
-36911271, -36913443 |
NM_001177323, NM_001177324, NM_001253706, NM_019942, BC010489 NM_001177323, NM_001177324, NM_001253706, NM_019942, BC010489 NM_001177323, NM_001177324, NM_001253706, NM_019942, BC010489 NM_001177323, NM_001177324, NM_001253706, NM_019942, BC010489 NM_001177323, NM_001177324, NM_001253706, NM_019942, BC010489 |
56526 |
56 |
nucleotide binding chromosome, centromeric region kinetochore GTPase activity protein binding GTP binding chromosome cytoplasm cytoskeleton cilium septin ring septin ring cell cycle spermatogenesis synaptic vesicle microtubule cytoskeleton cell differentiation septin complex septin complex septin complex motile cilium cell division site cleavage furrow septin collar cellular protein localization cell projection axon terminus cell division molecular adaptor activity cilium assembly cytoskeleton-dependent cytokinesis sperm annulus presynapse |
|
| TC0900001623.mm.2 |
Ss18l2 |
SS18, nBAF chromatin remodeling complex subunit like 2 |
9 |
121710388 |
NM_026794, BC027548 NM_026794, BC027548 |
26901 |
17 |
molecular_function transcription coactivator activity nucleus positive regulation of transcription by RNA polymerase II positive regulation of dendrite morphogenesis |
|
| TC0500000286.mm.2 |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
5 |
30155252 |
NM_001289798, NM_001289799, NM_145558, BC005585 NM_001289798, NM_001289799, NM_145558, BC005585 NM_001289798, NM_001289799, NM_145558, BC005585 NM_001289798, NM_001289799, NM_145558, BC005585 |
231086 |
40 |
catalytic activity acetyl-CoA C-acyltransferase activity acetyl-CoA C-acyltransferase activity acetyl-CoA C-acyltransferase activity mitochondrion mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane mitochondrial inner membrane endoplasmic reticulum lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation fatty acid beta-oxidation fatty acid beta-oxidation membrane mitochondrial fatty acid beta-oxidation multienzyme complex mitochondrial fatty acid beta-oxidation multienzyme complex transferase activity transferase activity, transferring acyl groups transferase activity, transferring acyl groups other than amino-acyl groups mitochondrial nucleoid protein-containing complex binding acetyl-CoA C-myristoyltransferase activity |
00062 00071 00280 01100 |
| TC0900002036.mm.2 |
Chek1 |
checkpoint kinase 1 |
9 |
-36708481 |
NM_007691, BC100386 NM_007691, BC100386 |
12649 |
117 |
DNA damage checkpoint DNA damage checkpoint DNA damage checkpoint G2/M transition of mitotic cell cycle nucleotide binding chromosome, telomeric region chromatin condensed nuclear chromosome inner cell mass cell proliferation protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm nucleoplasm replication fork chromosome cytoplasm cytoplasm centrosome cytoskeleton DNA repair DNA repair protein phosphorylation protein phosphorylation protein phosphorylation apoptotic process cellular response to DNA damage stimulus cellular response to DNA damage stimulus DNA damage induced protein phosphorylation nucleus organization cell cycle mitotic cell cycle checkpoint regulation of gene expression regulation of double-strand break repair via homologous recombination regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage negative regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-threonine phosphorylation protein domain specific binding protein-containing complex histone kinase activity (H3-T11 specific) histone kinase activity (H3-T11 specific) intracellular signal transduction regulation of cell population proliferation intracellular membrane-bounded organelle mitotic G2/M transition checkpoint positive regulation of cell cycle negative regulation of mitotic nuclear division regulation of mitotic centrosome separation chromatin-mediated maintenance of transcription signal transduction involved in G2 DNA damage checkpoint apoptotic process involved in development negative regulation of DNA biosynthetic process regulation of histone H3-K9 acetylation |
04110 04115 |
| TC1500001192.mm.2 |
Skp2 |
S-phase kinase-associated protein 2 |
15 |
-9111981, -9111981 |
NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468 NM_001285980, NM_013787, BC092236, NM_145468 |
27401 |
133 |
G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle protein polyubiquitination protein binding nucleus nucleoplasm nucleolus cytoplasm cytosol cytosol ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex SCF ubiquitin ligase complex SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of intracellular estrogen receptor signaling pathway identical protein binding regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process innate immune response positive regulation of smooth muscle cell proliferation defense response to virus regulation of cell cycle regulation of cell cycle protein K48-linked ubiquitination positive regulation of protein polyubiquitination |
04110 04120 05200 05222 |
| TC1200002002.mm.2 |
Erh |
ERH mRNA splicing and mitosis factor |
12 |
-80634020 |
NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 NM_007951, BC083141, BC099476, BC107315, BC107316, BC132421, BC132423 |
13877 |
34 |
osteoblast differentiation nucleus methyl-CpG binding membrane midbody methylosome |
|
| TC0300002916.mm.2 |
Ap1ar |
adaptor-related protein complex 1 associated regulatory protein |
3 |
-127807006 |
NM_145964 |
211556 |
20 |
negative regulation of receptor recycling endosome endosome Golgi apparatus kinesin binding kinesin binding transport vesicle regulation of Arp2/3 complex-mediated actin nucleation regulation of Arp2/3 complex-mediated actin nucleation cellular protein localization AP-1 adaptor complex binding AP-1 adaptor complex binding vesicle targeting, trans-Golgi to endosome vesicle targeting, trans-Golgi to endosome Arp2/3 complex binding negative regulation of substrate adhesion-dependent cell spreading negative regulation of substrate adhesion-dependent cell spreading negative regulation of cell motility |
|
| TC0400004136.mm.2 |
Ski |
ski sarcoma viral oncogene homolog (avian) |
4 |
-155154074 |
NM_011385, BC068305 NM_011385, BC068305 |
20481 |
67 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific neural tube closure lens morphogenesis in camera-type eye chromatin binding transcription corepressor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm centrosome transcription, DNA-templated zinc ion binding negative regulation of cell population proliferation anterior/posterior axis specification negative regulation of Schwann cell proliferation myotube differentiation myotube differentiation myotube differentiation nuclear body PML body transcription repressor complex protein kinase binding protein domain specific binding olfactory bulb development myelination in peripheral nervous system embryonic limb morphogenesis negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway negative regulation of BMP signaling pathway negative regulation of BMP signaling pathway ubiquitin protein ligase binding negative regulation of activin receptor signaling pathway protein-containing complex somatic stem cell population maintenance identical protein binding camera-type eye development positive regulation of DNA binding nose morphogenesis negative regulation of osteoblast differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II SMAD binding SMAD binding histone deacetylase inhibitor activity negative regulation of fibroblast proliferation camera-type eye morphogenesis skeletal muscle fiber development roof of mouth development retina development in camera-type eye face morphogenesis bone morphogenesis SMAD protein signal transduction repressing transcription factor binding |
|
| TC1300002198.mm.2 |
Cdc14b |
CDC14 cell division cycle 14B |
13 |
-64192544, -64192544 |
NM_001122989, NM_172587, BC049794, BC057357 NM_001122989, NM_172587, BC049794, BC057357 NM_001122989, NM_172587, BC049794, BC057357 NM_001122989, NM_172587, BC049794, BC057357 |
218294 |
26 |
microtubule cytoskeleton organization mitotic cell cycle spindle pole phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity nucleus nucleoplasm nucleolus nucleolus cytoplasm centrosome DNA repair protein dephosphorylation cellular response to DNA damage stimulus regulation of exit from mitosis protein tyrosine/serine/threonine phosphatase activity dephosphorylation hydrolase activity phosphatase activity G2 DNA damage checkpoint positive regulation of cytokinesis cilium assembly mitotic cell cycle arrest signal transduction involved in G2 DNA damage checkpoint mitotic spindle positive regulation of ubiquitin protein ligase activity |
04110 |
| TC1000001686.mm.2 |
Fbxo5 |
F-box protein 5 |
10 |
-5799157 |
NM_025995, BC053434 NM_025995, BC053434 |
67141 |
29 |
oocyte maturation oocyte maturation protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm spindle cytoskeleton regulation of DNA replication cell cycle spindle assembly involved in female meiosis I regulation of mitotic nuclear division regulation of mitotic cell cycle positive regulation of cell population proliferation positive regulation of G2/M transition of mitotic cell cycle anaphase-promoting complex binding vesicle organization protein kinase binding negative regulation of DNA endoreduplication regulation of meiotic nuclear division positive regulation of osteoblast differentiation negative regulation of meiotic nuclear division negative regulation of meiotic nuclear division negative regulation of mitotic metaphase/anaphase transition microtubule polymerization metal ion binding spindle assembly cell division negative regulation of ubiquitin-protein transferase activity positive regulation of meiosis I positive regulation of biomineral tissue development meiotic spindle negative regulation of ubiquitin protein ligase activity positive regulation of mesenchymal stem cell migration ubiquitin ligase inhibitor activity negative regulation of cellular senescence negative regulation of response to DNA damage stimulus |
04114 |
| TC0100000282.mm.2 |
Npas2 |
neuronal PAS domain protein 2 |
1 |
39194271 |
NM_008719, BC109166 NM_008719, BC109166 |
18143 |
63 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm cytosol cytosol regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cellular response to DNA damage stimulus circadian rhythm circadian regulation of gene expression circadian regulation of gene expression response to drug circadian sleep/wake cycle regulation of circadian rhythm locomotor rhythm positive regulation of DNA repair positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II metal ion binding protein dimerization activity rhythmic process response to redox state response to redox state Hsp90 protein binding negative regulation of cell death CLOCK-BMAL transcription complex sequence-specific double-stranded DNA binding positive regulation of behavioral fear response regulation of response to DNA damage stimulus |
04710 |
| TC0700003038.mm.2 |
Saal1 |
serum amyloid A-like 1 |
7 |
-46686107 |
NM_030233, BC087944 NM_030233, BC087944 |
78935 |
20 |
molecular_function nucleus nucleoplasm positive regulation of synoviocyte proliferation |
|
| TC0200001911.mm.2 |
Stard7 |
START domain containing 7 |
2 |
127270228, 127270228, 127270228 |
NM_139308, BC017524, BC080747 NM_139308, BC017524, BC080747 NM_139308, BC017524, BC080747 |
99138 |
25 |
myeloid dendritic cell activation extracellular region cytoplasm mitochondrion inflammatory response lipid binding T-helper 2 cell cytokine production type 2 immune response establishment of skin barrier mucociliary clearance |
|
| TC1300002766.mm.2 |
Nsun2 |
NOL1/NOP2/Sun domain family member 2 |
13 |
69612015 |
NM_145354, BC013625 NM_145354, BC013625 |
28114 |
49 |
tRNA binding RNA methylation in utero embryonic development RNA binding extracellular region nucleus nucleolus cytoplasm cytoplasm mitochondrion cytoskeleton cell cycle spermatogenesis spermatid development tRNA processing methyltransferase activity regulation of mRNA export from nucleus tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity transferase activity cell differentiation tRNA methylation tRNA methylation tRNA methylation tRNA methylation methylation meiotic cell cycle checkpoint chromatoid body tRNA stabilization hair follicle maturation cell division mRNA (cytidine-5-)-methyltransferase activity mRNA (cytidine-5-)-methyltransferase activity extracellular exosome mRNA methylation mRNA methylation regulation of stem cell differentiation |
|
| TC0800001863.mm.2 |
Ckap2 |
cytoskeleton associated protein 2 |
8 |
-22168151 |
NM_001004140, BC145666, BC146023 NM_001004140, BC145666, BC146023 NM_001004140, BC145666, BC146023 |
80986 |
26 |
mitotic cytokinesis molecular_function cytoplasm centrosome cytosol cytoskeleton microtubule apoptotic process negative regulation of microtubule depolymerization cell cycle microtubule cytoskeleton microtubule cytoskeleton positive regulation of transcription by RNA polymerase II |
|
| TC1400001671.mm.2 |
Stab1 |
stabilin 1 |
14 |
-31139016 |
NM_138672 |
192187 |
42 |
low-density lipoprotein particle receptor activity scavenger receptor activity calcium ion binding hyaluronic acid binding cytoplasm integral component of plasma membrane inflammatory response cell adhesion cell-cell signaling membrane integral component of membrane negative regulation of angiogenesis low-density lipoprotein particle binding defense response to bacterium |
|
| TC1000000047.mm.2 |
Nup43 |
nucleoporin 43 |
10 |
7667503 |
NM_145706, BC011060 NM_145706, BC011060 |
69912 |
16 |
chromosome, centromeric region kinetochore molecular_function nucleus nuclear pore nucleoplasm chromosome cytosol cell cycle chromosome segregation protein transport nuclear speck nuclear pore outer ring nuclear pore outer ring mRNA transport cell division |
03013 |
| TC0X00000958.mm.2 |
Kif4 |
kinesin family member 4 |
X |
100626064 |
NM_008446, BC050946 NM_008446, BC050946 |
16571 |
43 |
nucleotide binding mitotic cytokinesis DNA binding microtubule motor activity ATP binding nucleus nucleoplasm chromosome cytoplasm cytosol cytoskeleton microtubule microtubule-based movement mitotic spindle organization microtubule binding midbody metal ion binding mitotic spindle midzone assembly iron-sulfur cluster binding |
|
| TC0700002056.mm.2 |
Tspan4 |
tetraspanin 4 |
7 |
141476379, 141475235 |
NM_001252588, NM_053082, BC003482, BC083070 NM_001252588, NM_053082, BC003482, BC083070 NM_001252588, NM_053082, BC003482, BC083070 NM_001252588, NM_053082, BC003482, BC083070 |
64540 |
24 |
antigen binding integrin binding protein binding plasma membrane integral component of plasma membrane membrane integral component of membrane vesicle protein-containing complex assembly |
|
| TC0X00002825.mm.2 |
Magt1 |
magnesium transporter 1 |
X |
-105968084 |
NM_001190409, NM_025952, BC003881 NM_001190409, NM_025952, BC003881 NM_001190409, NM_025952, BC003881 |
67075 |
22 |
endoplasmic reticulum plasma membrane protein N-linked glycosylation oligosaccharyltransferase complex oligosaccharyltransferase complex magnesium ion transmembrane transporter activity magnesium ion transport membrane integral component of membrane protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine cognition |
|
| TC0400003742.mm.2 |
Man1c1 |
mannosidase, alpha, class 1C, member 1 |
4 |
-134561689 |
NM_207237, BC067023 NM_207237, BC067023 |
230815 |
15 |
Golgi membrane mannosyl-oligosaccharide 1,2-alpha-mannosidase activity mannosyl-oligosaccharide 1,2-alpha-mannosidase activity calcium ion binding endoplasmic reticulum Golgi apparatus mannose metabolic process N-glycan processing proteoglycan biosynthetic process |
00510 01100 04141 |
| TC0100000399.mm.2 |
Mars2 |
methionine-tRNA synthetase 2 (mitochondrial) |
1 |
55237176 |
NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739 NM_175439, BC099669, BC132343, BC137739 |
212679 |
20 |
nucleotide binding aminoacyl-tRNA ligase activity methionine-tRNA ligase activity methionine-tRNA ligase activity ATP binding mitochondrion mitochondrial matrix translation tRNA aminoacylation for protein translation methionyl-tRNA aminoacylation methionyl-tRNA aminoacylation ligase activity |
00450 00970 |
| TC1400000858.mm.2 |
Sacs |
sacsin |
14 |
61138456, 61138456 |
NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956 NM_172809, BC138482, BC138483, BC171956 |
50720 |
26 |
cytoplasm Hsp70 protein binding low-density lipoprotein particle receptor binding chaperone binding |
|
| TC0200000319.mm.2 |
Etl4 |
enhancer trap locus 4 |
2 |
20519512, 20289912, 20510046 |
NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 NM_001081006, NM_001177630, NM_001177631, NM_029895, NM_178059, BC158051 |
208618 |
46 |
protein binding cytoplasm cytoplasm multicellular organism development enzyme regulator activity embryonic skeletal system development |
|
| TC0200005496.mm.2 |
Fam78a |
family with sequence similarity 78, member A |
2 |
-32050054, -32050054, -32050054, -32066884 |
NM_175511, BC137951, BC137952 NM_175511, BC137951, BC137952 NM_175511, BC137951, BC137952 |
241303 |
11 |
molecular_function cellular_component biological_process |
|
| TC0700001192.mm.2 |
Mex3b |
mex3 RNA binding family member B |
7 |
82867332 |
NM_175366 |
108797 |
19 |
P-body nucleic acid binding RNA binding nucleus nucleoplasm cytoplasm cytosol positive regulation of cell-cell adhesion GTPase activating protein binding positive regulation of GTPase activity metal ion binding positive regulation of phagocytosis protein localization to cell cortex |
|
| TC1100001359.mm.2 |
Srsf1 |
serine and arginine-rich splicing factor 1 |
11 |
88047372 |
NM_001078167, NM_173374, BC046773, BC058627 NM_001078167, NM_173374, BC046773, BC058627 NM_001078167, NM_173374, BC046773, BC058627 NM_001078167, NM_173374, BC046773, BC058627 |
110809 |
79 |
alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome mRNA 5'-splice site recognition mRNA splicing, via spliceosome in utero embryonic development nucleic acid binding RNA binding RNA binding mRNA binding protein binding nucleus nucleus nucleoplasm spliceosomal complex cytoplasm mRNA processing RNA splicing RNA splicing nuclear speck nuclear speck nuclear speck positive regulation of RNA splicing exon-exon junction complex protein kinase B binding DNA topoisomerase binding RS domain binding mRNA transport cardiac muscle contraction catalytic step 2 spliceosome |
03040 |
| TC0900001419.mm.2 |
Prkar2a |
protein kinase, cAMP dependent regulatory, type II alpha |
9 |
108692142 |
NM_008924, BC075623, BC080276 NM_008924, BC075623, BC080276 NM_008924, BC075623, BC080276 |
19087 |
78 |
nucleotide binding regulation of protein phosphorylation cAMP-dependent protein kinase inhibitor activity protein binding cytoplasm cytoplasm centrosome cytosol plasma membrane axoneme cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex cAMP-dependent protein kinase regulator activity cAMP-dependent protein kinase regulator activity regulation of protein kinase A signaling membrane protein domain specific binding T-tubule cAMP binding nucleotide-activated protein kinase complex ubiquitin protein ligase binding beta-2 adrenergic receptor binding protein-containing complex protein kinase A catalytic subunit binding small molecule binding identical protein binding regulation of cAMP-mediated signaling plasma membrane raft protein-containing complex binding synapse synapse regulation of protein kinase activity perinuclear region of cytoplasm modulation of chemical synaptic transmission glutamatergic synapse glutamatergic synapse glutamatergic synapse negative regulation of cAMP-dependent protein kinase activity |
04210 04910 |
| TC0200000495.mm.2 |
Ddx31 |
DEAD/H box helicase 31 |
2 |
28840405 |
NM_001033294, BC066017, BC132351 NM_001033294, BC066017, BC132351 NM_001033294, BC066017, BC132351 |
227674 |
13 |
nucleotide binding nucleic acid binding RNA binding helicase activity ATP binding nucleus nucleolus Golgi apparatus hydrolase activity ribosome biogenesis ribosome biogenesis intracellular membrane-bounded organelle |
|
| TC0500001865.mm.2 |
Brca2 |
breast cancer 2, early onset |
5 |
150522620 |
NM_001081001, NM_009765, BC172649 NM_001081001, NM_009765, BC172649 NM_001081001, NM_009765, BC172649 |
12190 |
178 |
telomere maintenance via recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromosome, telomeric region lateral element oocyte maturation inner cell mass cell proliferation protease binding DNA binding single-stranded DNA binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm centrosome cytosol cytoskeleton DNA repair nucleotide-excision repair double-strand break repair double-strand break repair DNA recombination regulation of transcription, DNA-templated cellular response to DNA damage stimulus DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle male meiosis I male meiosis I spermatogenesis spermatogenesis brain development cell aging protein C-terminus binding cell population proliferation female gonad development intrinsic apoptotic signaling pathway in response to DNA damage response to X-ray response to UV-C response to gamma radiation H3 histone acetyltransferase activity H4 histone acetyltransferase activity hemopoiesis secretory granule mammary gland development homologous chromosome orientation involved in meiotic metaphase I plate congression regulation of cytokinesis protein-containing complex BRCA2-MAGE-D1 complex negative regulation of mammary gland epithelial cell proliferation multicellular organism growth intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding chordate embryonic development gamma-tubulin binding histone H3 acetylation histone H4 acetylation positive regulation of transcription, DNA-templated positive regulation of mitotic cell cycle replication fork protection chromosome organization centrosome duplication establishment of protein localization to telomere establishment of protein localization to telomere mitotic recombination-dependent replication fork processing |
03440 05200 05212 |
| TC0100002936.mm.2 |
Tsn |
translin |
1 |
-118298513, -118298513 |
NM_011650, BC004615 NM_011650, BC004615 |
22099 |
53 |
DNA binding single-stranded DNA binding RNA binding mRNA binding nuclease activity endonuclease activity endoribonuclease activity protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm endoplasmic reticulum RNA metabolic process hydrolase activity identical protein binding sequence-specific DNA binding protein-containing complex binding |
|
| TC0200005489.mm.2 |
Zfp965 |
zinc finger protein 965 |
2 |
175470024 |
NM_001242944 |
100503949 |
1 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific nucleoplasm regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| TC1300001560.mm.2 |
H1f5 |
H1.5 linker histone, cluster member |
13 |
-21779831 |
NM_020034, BC146469 NM_020034, BC146469 |
56702 |
34 |
nucleosome DNA binding double-stranded DNA binding protein binding nucleus chromosome nucleosome assembly muscle organ development nucleosome positioning chromosome condensation nucleosomal DNA binding negative regulation of chromatin silencing negative regulation of DNA recombination |
|
| TC0700004587.mm.2 |
Nap1l4 |
nucleosome assembly protein 1-like 4 |
7 |
-143513578, -143513578 |
NM_001285489, NM_001285490, NM_008672, BC132039, BC138518, BC145306, BC145308 NM_001285489, NM_001285490, NM_008672, BC132039, BC138518, BC145306, BC145308 NM_001285489, NM_001285490, NM_008672, BC132039, BC138518, BC145306, BC145308 NM_001285489, NM_001285490, NM_008672, BC132039, BC138518, BC145306, BC145308 NM_001285489, NM_001285490, NM_008672, BC132039, BC138518, BC145306, BC145308 NM_001285489, NM_001285490, NM_008672, BC132039, BC138518, BC145306, BC145308 NM_001285489, NM_001285490, NM_008672, BC132039, BC138518, BC145306, BC145308 |
17955 |
43 |
chromatin chromatin binding nucleus nucleus cytoplasm nucleosome assembly nucleosome assembly nucleosome assembly dendrite nucleosome binding histone binding neuronal cell body |
|
| TC0800002236.mm.2 |
Spcs3 |
signal peptidase complex subunit 3 homolog (S. cerevisiae) |
8 |
-54520432 |
NM_029701, BC054817 NM_029701, BC054817 |
76687 |
18 |
endoplasmic reticulum signal peptidase complex signal peptide processing proteolysis peptidase activity membrane integral component of membrane hydrolase activity viral protein processing intracellular membrane-bounded organelle protein targeting to ER |
03060 |
| TC1900001454.mm.2 |
Ide |
insulin degrading enzyme |
19 |
-37268742 |
NM_031156, BC041675 NM_031156, BC041675 |
15925 |
65 |
nucleotide binding amyloid-beta binding catalytic activity endopeptidase activity metalloendopeptidase activity ATP binding extracellular region extracellular space nucleus cytoplasm mitochondrion mitochondrion mitochondrion peroxisome peroxisomal matrix peroxisomal matrix cytosol plasma membrane proteolysis response to oxidative stress metabolic process peptidase activity metallopeptidase activity zinc ion binding determination of adult lifespan external side of plasma membrane cell surface bradykinin catabolic process ubiquitin recycling membrane basolateral plasma membrane hydrolase activity ATPase activity peptide hormone binding antigen processing and presentation of endogenous peptide antigen via MHC class I protein catabolic process cytosolic proteasome complex beta-endorphin binding positive regulation of protein binding peptide binding hormone catabolic process hormone catabolic process identical protein binding protein homodimerization activity peptide catabolic process peptide catabolic process insulin binding cellular protein catabolic process protein-containing complex binding negative regulation of proteolysis metal ion binding amyloid-beta metabolic process amyloid-beta metabolic process proteolysis involved in cellular protein catabolic process proteolysis involved in cellular protein catabolic process extracellular exosome amyloid-beta clearance amyloid-beta clearance amyloid-beta clearance ubiquitin-dependent protein binding amyloid-beta clearance by cellular catabolic process insulin metabolic process insulin catabolic process insulin catabolic process regulation of aerobic respiration |
05010 |
| TC1800001741.mm.2 |
|
|
|
|
NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 NM_033574, NM_033575, NM_033576, NM_033577, NM_033578, NM_033579, NM_033580, NM_033581, NM_033582, NM_033583, NM_033584, NM_033585, NM_033586, NM_033587, NM_033588, NM_033589, NM_033590, NM_033591, NM_033592, NM_033593, NM_033594, NM_033595, BC035540, BC049814, BC054528, BC054555, BC054556, BC054557, BC054741, BC054787, BC056998, BC057404, BC059175, BC059837, BC060691, BC064675, BC064808, BC066823, BC066851, BC077712, BC079567, BC080852, BC098367, BC098457, BC138677, BC138678, BC138701, BC139099, BC139100, BC139178, BC160199, BC167188 |
|
|
molecular_function calcium ion binding protein binding plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane cell-cell junction cell-cell junction cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules homophilic cell adhesion via plasma membrane adhesion molecules biological_process endosome to lysosome transport membrane integral component of membrane calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules growth cone synapse organization lipid tube assembly involved in organelle fusion |
|
| TC0900001792.mm.2 |
Fat3 |
FAT atypical cadherin 3 |
9 |
-15910189 |
NM_001080814 |
270120 |
25 |
cell morphogenesis involved in differentiation neuron migration calcium ion binding plasma membrane cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules multicellular organism development retina layer formation membrane integral component of membrane dendrite cell-cell adhesion negative regulation of dendrite development |
|
| TC0700001343.mm.2 |
Nars2 |
asparaginyl-tRNA synthetase 2 (mitochondrial)(putative) |
7 |
96951526 |
NM_153591, BC030041 NM_153591, BC030041 |
244141 |
18 |
nucleotide binding nucleic acid binding aminoacyl-tRNA ligase activity asparagine-tRNA ligase activity ATP binding nucleoplasm mitochondrion mitochondrion cytosol translation tRNA aminoacylation for protein translation asparaginyl-tRNA aminoacylation ligase activity |
00970 |
| TC1200000334.mm.2 |
Agmo |
alkylglycerol monooxygenase |
12 |
37241638 |
NM_178767, BC148840 NM_178767, BC148840 |
319660 |
14 |
iron ion binding endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process membrane lipid metabolic process lipid biosynthetic process membrane integral component of membrane oxidoreductase activity ether lipid metabolic process glyceryl-ether monooxygenase activity glyceryl-ether monooxygenase activity |
|
| TC0500000852.mm.2 |
Mthfd2l |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
5 |
90931195 |
NM_026788 |
665563 |
17 |
histidine biosynthetic process catalytic activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity mitochondrion mitochondrial inner membrane mitochondrial matrix purine nucleotide biosynthetic process one-carbon metabolic process metabolic process cellular amino acid biosynthetic process methionine biosynthetic process 10-formyltetrahydrofolate metabolic process membrane oxidoreductase activity hydrolase activity tetrahydrofolate interconversion tetrahydrofolate interconversion |
00670 01100 |
| TC1700002561.mm.2 |
Cebpz |
CCAAT/enhancer binding protein zeta |
17 |
-78919002 |
NM_001024806, BC160197 NM_001024806, BC160197 |
12607 |
24 |
transcription coactivator activity nucleus nucleus ribosome biogenesis positive regulation of transcription by RNA polymerase II |
|
| TC1600001527.mm.2 |
Umps |
uridine monophosphate synthetase |
16 |
-33954781 |
NM_009471, BC003887, BC095981 NM_009471, BC003887, BC095981 NM_009471, BC003887, BC095981 |
22247 |
30 |
catalytic activity orotate phosphoribosyltransferase activity orotate phosphoribosyltransferase activity orotidine-5'-phosphate decarboxylase activity orotidine-5'-phosphate decarboxylase activity nucleus cytoplasm 'de novo' pyrimidine nucleobase biosynthetic process pyrimidine nucleotide biosynthetic process UMP biosynthetic process UMP biosynthetic process metabolic process nucleoside metabolic process transferase activity transferase activity, transferring glycosyl groups lyase activity carboxy-lyase activity pyrimidine nucleobase biosynthetic process identical protein binding 'de novo' UMP biosynthetic process |
00240 00983 01100 |
| TC1500001791.mm.2 |
Arhgap39 |
Rho GTPase activating protein 39 |
15 |
-76723984 |
NM_001168288, NM_198420, BC060637 NM_001168288, NM_198420, BC060637 NM_001168288, NM_198420, BC060637 |
223666 |
31 |
GTPase activator activity nucleus cytoplasm cytoskeleton signal transduction postsynapse glutamatergic synapse postsynapse organization |
|
| TC1700002562.mm.2 |
Prkd3 |
protein kinase D3 |
17 |
-78949404, -78949404 |
NM_001171004, NM_001171005, NM_029239, BC037012, BC089164 NM_001171004, NM_001171005, NM_029239, BC037012, BC089164 NM_001171004, NM_001171005, NM_029239, BC037012, BC089164 NM_001171004, NM_001171005, NM_029239, BC037012, BC089164 NM_001171004, NM_001171005, NM_029239, BC037012, BC089164 |
75292 |
36 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein kinase C activity ATP binding nucleoplasm cytoplasm cytosol protein phosphorylation membrane kinase activity phosphorylation transferase activity intracellular signal transduction metal ion binding protein kinase D signaling |
|
| TC0700003045.mm.2 |
Uevld |
UEV and lactate/malate dehyrogenase domains |
7 |
-46923215 |
NM_001040695, BC054796 NM_001040695, BC054796 |
54122 |
18 |
catalytic activity carbohydrate metabolic process cellular protein modification process protein transport oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor carboxylic acid metabolic process |
|
| TC0200001951.mm.2 |
Slc20a1 |
solute carrier family 20, member 1 |
2 |
129198772, 129207095, 129198772 |
NM_001159593, NM_015747, BC015085 NM_001159593, NM_015747, BC015085 NM_001159593, NM_015747, BC015085 |
20515 |
63 |
inorganic phosphate transmembrane transporter activity high-affinity inorganic phosphate:sodium symporter activity plasma membrane integral component of plasma membrane sodium ion transport phosphate ion transport symporter activity membrane integral component of membrane biomineral tissue development phosphate ion transmembrane transport |
|
| TC1500002037.mm.2 |
Hdac10 |
histone deacetylase 10 |
15 |
-89123302 |
NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 NM_199198, NR_028447, NR_028448, NR_028449, BC064018 |
170787 |
24 |
histone deacetylase complex negative regulation of transcription by RNA polymerase II histone deacetylase activity nucleus nucleoplasm cytoplasm DNA repair DNA recombination regulation of transcription, DNA-templated autophagy cellular response to DNA damage stimulus macroautophagy histone deacetylation hydrolase activity deacetylase activity enzyme binding positive regulation of mismatch repair peptidyl-lysine deacetylation homologous recombination histone deacetylase binding negative regulation of transcription, DNA-templated metal ion binding acetylputrescine deacetylase activity acetylspermidine deacetylase activity polyamine deacetylation spermidine deacetylation |
|
| TC0500001428.mm.2 |
Kntc1 |
kinetochore associated 1 |
5 |
123749725 |
NM_001042421 |
208628 |
20 |
chromosome, centromeric region kinetochore spindle pole molecular_function nucleus chromosome cytoplasm kinetochore microtubule cytosol cytoskeleton plasma membrane cell cycle mitotic spindle assembly checkpoint actin cytoskeleton cell division RZZ complex |
|
| TC1400002260.mm.2 |
Esco2 |
establishment of sister chromatid cohesion N-acetyltransferase 2 |
14 |
-65819026 |
NM_028039, BC033303, BC071275 NM_028039, BC033303, BC071275 NM_028039, BC033303, BC071275 |
71988 |
35 |
chromatin XY body hematopoietic progenitor cell differentiation lysine N-acetyltransferase activity, acting on acetyl phosphate as donor nucleus nucleoplasm chromosome pericentric heterochromatin Golgi apparatus regulation of DNA replication regulation of DNA replication double-strand break repair cell cycle chromosome segregation sister chromatid cohesion chromocenter acetyltransferase activity transferase activity transferase activity, transferring acyl groups cell junction post-translational protein acetylation post-translational protein acetylation site of double-strand break metal ion binding protein localization to chromatin |
|
| TC1000001737.mm.2 |
Stxbp5 |
syntaxin binding protein 5 (tomosyn) |
10 |
-9755546 |
NM_001081344 |
78808 |
33 |
GTPase activator activity protein binding cytoplasm cytosol plasma membrane acetylcholine-gated channel complex exocytosis axonogenesis synaptic vesicle regulation of synaptic vesicle priming regulation of synaptic vesicle priming regulation of synaptic vesicle priming protein transport membrane syntaxin-1 binding syntaxin-1 binding syntaxin-1 binding regulation of exocytosis regulation of exocytosis syntaxin binding syntaxin binding secretory granule SNARE complex neuromuscular junction myosin II binding positive regulation of exocytosis regulation of protein secretion extrinsic component of neuronal dense core vesicle membrane extrinsic component of neuronal dense core vesicle membrane Schaffer collateral - CA1 synapse hippocampal mossy fiber to CA3 synapse hippocampal mossy fiber to CA3 synapse presynapse extrinsic component of presynaptic membrane synaptic vesicle cycle presynaptic cytosol regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis |
|
| TC1300001762.mm.2 |
Serpinb1a |
serine (or cysteine) peptidase inhibitor, clade B, member 1a |
13 |
-32842091 |
NM_025429, BC011140, BC104333 NM_025429, BC011140, BC104333 NM_025429, BC011140, BC104333 |
66222 |
39 |
serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular region extracellular space cytoplasm inflammatory response negative regulation of peptidase activity negative regulation of endopeptidase activity negative regulation of endopeptidase activity cellular homeostasis peptidase inhibitor activity negative regulation of interleukin-1 beta production negative regulation of interleukin-1 beta production cytoplasmic ribonucleoprotein granule regulation of protein catabolic process type B pancreatic cell proliferation type B pancreatic cell proliferation regulation of innate immune response collagen-containing extracellular matrix |
05146 |
| TC0100001853.mm.2 |
Ints7 |
integrator complex subunit 7 |
1 |
191575635 |
NM_178632, BC054120 NM_178632, BC054120 |
77065 |
25 |
DNA damage checkpoint molecular_function nucleus chromosome cytoplasm cellular response to DNA damage stimulus snRNA processing nuclear body integrator complex integrator complex snRNA 3'-end processing cellular response to ionizing radiation |
|
| TC0400001215.mm.2 |
Stil |
Scl/Tal1 interrupting locus |
4 |
115000117 |
NM_009185, BC141175, BC145493 NM_009185, BC141175, BC145493 NM_009185, BC141175, BC145493 |
20460 |
29 |
embryonic axis specification in utero embryonic development neural tube closure heart looping protein binding cytoplasm centrosome centrosome centriole centriole cytoskeleton mitotic spindle organization mitotic spindle organization smoothened signaling pathway smoothened signaling pathway multicellular organism development determination of left/right symmetry neural tube development forebrain development notochord development floor plate development multicellular organism growth identical protein binding negative regulation of apoptotic process positive regulation of cyclin-dependent protein serine/threonine kinase activity regulation of centriole replication centrosome duplication centrosome duplication centrosome duplication mitotic spindle checkpoint protein localization to centrosome protein localization to centrosome non-motile cilium assembly |
|
| TC1300000928.mm.2 |
Mctp1 |
multiple C2 domains, transmembrane 1 |
13 |
76384138, 76579596 |
NM_030174 |
78771 |
13 |
calcium ion binding calcium ion binding endosome endoplasmic reticulum membrane integral component of membrane integral component of membrane cell junction negative regulation of cell migration synaptic vesicle membrane synaptic vesicle membrane cytoplasmic vesicle synapse negative regulation of endocytosis metal ion binding regulation of neurotransmitter secretion recycling endosome negative regulation of response to oxidative stress |
|
| MG-1-pos-10342736_st |
|
|
|
|
|
|
|
|
|
| TC0300001639.mm.2 |
Fabp4 |
fatty acid binding protein 4, adipocyte |
3 |
-10204342 |
NM_024406, BC002148, BC054426 NM_024406, BC002148, BC054426 NM_024406, BC002148, BC054426 |
11770 |
198 |
cytokine production long-chain fatty acid transporter activity fatty acid binding nucleus nucleoplasm cytoplasm cytosol negative regulation of protein kinase activity fatty acid metabolic process positive regulation of cell population proliferation lipid binding response to bacterium long-chain fatty acid transport long-chain fatty acid binding cholesterol homeostasis negative regulation of transcription, DNA-templated regulation of inflammatory response positive regulation of inflammatory response white fat cell differentiation brown fat cell differentiation hormone receptor binding cellular response to lithium ion cellular response to tumor necrosis factor positive regulation of cold-induced thermogenesis |
03320 |
| TC0100000381.mm.2 |
Hibch |
3-hydroxyisobutyryl-Coenzyme A hydrolase |
1 |
52845037 |
NM_146108, BC026437 NM_146108, BC026437 |
227095 |
21 |
3-hydroxyisobutyryl-CoA hydrolase activity 3-hydroxyisobutyryl-CoA hydrolase activity mitochondrion mitochondrion mitochondrion valine catabolic process branched-chain amino acid catabolic process hydrolase activity |
00280 00410 00640 01100 |
| TC0700001131.mm.2 |
Ticrr |
TOPBP1-interacting checkpoint and replication regulator |
7 |
79660195 |
NM_029835, BC158103 NM_029835, BC158103 |
77011 |
18 |
chromatin binding chromatin binding nucleus nucleus nucleoplasm cytosol DNA replication DNA repair cellular response to DNA damage stimulus cell cycle mitotic G2 DNA damage checkpoint response to ionizing radiation regulation of DNA-dependent DNA replication initiation regulation of DNA-dependent DNA replication initiation mitotic DNA replication checkpoint intracellular membrane-bounded organelle |
|
| TC0300000623.mm.2 |
Ppid |
peptidylprolyl isomerase D (cyclophilin D) |
3 |
79591336 |
NM_026352, BC011499, BC019778 NM_026352, BC011499, BC019778 NM_026352, BC011499, BC019778 |
67738 |
32 |
negative regulation of transcription by RNA polymerase II protein peptidyl-prolyl isomerization protein peptidyl-prolyl isomerization peptidyl-prolyl cis-trans isomerase activity peptidyl-prolyl cis-trans isomerase activity peptidyl-prolyl cis-trans isomerase activity FK506 binding nucleus nucleoplasm nucleolus cytoplasm cytoplasm mitochondrion cytosol protein folding apoptotic process transcription factor binding protein transport cyclosporin A binding cyclosporin A binding isomerase activity enzyme binding heat shock protein binding lipid droplet organization positive regulation of apoptotic process positive regulation of viral genome replication positive regulation of protein secretion Hsp90 protein binding chaperone-mediated protein folding protein-containing complex assembly cellular response to UV-A |
04020 05012 05016 |
| TC1000002594.mm.2 |
Ckap4 |
cytoskeleton-associated protein 4 |
10 |
-84526304 |
NM_175451, BC138318, BC138320 NM_175451, BC138318, BC138320 NM_175451, BC138318, BC138320 |
216197 |
30 |
cytoplasm endoplasmic reticulum endoplasmic reticulum rough endoplasmic reticulum rough endoplasmic reticulum lipid droplet cytosol cytoskeleton plasma membrane biological_process cell surface membrane integral component of membrane nuclear speck cytoplasmic ribonucleoprotein granule |
04141 |
| TC0700001442.mm.2 |
Anapc15 |
anaphase promoting complex C subunit 15 |
7 |
101881324, 101896330, 101885859 |
NM_027532, BC006736, BC080730 NM_027532, BC006736, BC080730 NM_027532, BC006736, BC080730 |
75430 |
20 |
molecular_function anaphase-promoting complex cell cycle cell division regulation of mitotic cell cycle spindle assembly checkpoint |
|
| TC0200002043.mm.2 |
Mcm8 |
minichromosome maintenance 8 homologous recombination repair factor |
2 |
132816140 |
NM_025676, BC046780, BC052070 NM_025676, BC046780, BC052070 NM_025676, BC046780, BC052070 |
66634 |
19 |
nucleotide binding double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination DNA binding chromatin binding DNA replication origin binding single-stranded DNA binding helicase activity ATP binding nucleus nucleus nucleoplasm chromosome cytosol DNA replication DNA replication initiation DNA repair cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle female gamete generation hydrolase activity enzyme binding MutLbeta complex binding MutSalpha complex binding MutSbeta complex binding recombinational interstrand cross-link repair MCM complex male gamete generation protein stabilization protein localization to chromatin MCM8-MCM9 complex MCM8-MCM9 complex |
|
| TC0600003474.mm.2 |
Sinhcaf |
SIN3-HDAC complex associated factor |
6 |
-148921058, -148921058 |
NM_019643, BC076599 NM_019643, BC076599 |
56306 |
28 |
protein binding nucleus positive regulation of cell population proliferation Sin3 complex Sin3 complex negative regulation of cell migration negative regulation of cell migration negative regulation of cell differentiation |
|
| MG-1-pos-10340206_st |
|
|
|
|
|
|
|
|
|
| TC1600002169.mm.2 |
Dnaja3 |
DnaJ heat shock protein family (Hsp40) member A3 |
16 |
4684069 |
NM_001135112, NM_023646, BC027240 NM_001135112, NM_023646, BC027240 NM_001135112, NM_023646, BC027240 |
83945 |
40 |
negative regulation of transcription by RNA polymerase II interferon-gamma receptor binding protein binding ATP binding nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial matrix cytosol cytosol actin filament plasma membrane mitochondrial DNA replication protein folding negative regulation of protein kinase activity apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process activation-induced cell death of T cells mitochondrion organization mitochondrion organization small GTPase mediated signal transduction neuromuscular junction development neuromuscular junction development cell aging transcription factor binding negative regulation of cell population proliferation response to heat embryo development membrane extrinsic component of plasma membrane protein kinase binding cell junction Hsp70 protein binding GTPase regulator activity receptor tyrosine kinase binding heat shock protein binding positive regulation of protein ubiquitination neuromuscular junction negative regulation of NF-kappaB transcription factor activity T cell differentiation in thymus response to interferon-gamma positive regulation of T cell proliferation mitochondrial nucleoid regulation of apoptotic process positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of programmed cell death negative regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of cysteine-type endopeptidase activity involved in apoptotic process intracellular membrane-bounded organelle protein-containing complex binding synapse postsynaptic membrane metal ion binding protein stabilization NF-kappaB binding unfolded protein binding negative regulation of interferon-gamma-mediated signaling pathway skeletal muscle acetylcholine-gated channel clustering IkappaB kinase complex binding |
|
| TC0800002960.mm.2 |
Adat1 |
adenosine deaminase, tRNA-specific 1 |
8 |
-111970864, -111966897 |
NM_013925, BC019976 NM_013925, BC019976 |
30947 |
14 |
RNA binding adenosine deaminase activity cellular_component RNA processing tRNA processing tRNA-specific adenosine deaminase activity tRNA-specific adenosine deaminase activity hydrolase activity metal ion binding |
|
| TC1800001700.mm.2 |
Tshz1 |
teashirt zinc finger family member 1 |
18 |
-84011626, -84011626 |
NM_001081300, BC058264 NM_001081300, BC058264 |
110796 |
47 |
DNA-binding transcription factor activity, RNA polymerase II-specific nucleic acid binding DNA binding protein binding nucleus regulation of transcription by RNA polymerase II multicellular organism development anterior/posterior pattern specification regulation of gene expression middle ear morphogenesis metal ion binding soft palate development |
|
| TC1100003945.mm.2 |
Nol11 |
nucleolar protein 11 |
11 |
-107166652 |
NM_001161329, NM_133702, BC024874 NM_001161329, NM_133702, BC024874 NM_001161329, NM_133702, BC024874 |
68979 |
19 |
nucleus nucleolus nucleolus rRNA processing maturation of SSU-rRNA maturation of SSU-rRNA t-UTP complex ribosome biogenesis positive regulation of transcription of nucleolar large rRNA by RNA polymerase I |
|
| TC1100003694.mm.2 |
Tns4 |
tensin 4 |
11 |
-99065677 |
NM_172564, BC055820 NM_172564, BC055820 |
217169 |
15 |
molecular_function actin binding cytoplasm cytoskeleton focal adhesion apoptotic process protein localization cell junction |
|
| TC0400002637.mm.2 |
Mrpl50 |
mitochondrial ribosomal protein L50 |
4 |
-49512596 |
NM_178603, BC021318 NM_178603, BC021318 |
28028 |
21 |
molecular_function mitochondrion mitochondrion mitochondrial large ribosomal subunit mitochondrial large ribosomal subunit ribosome biological_process |
|
| TC0600001709.mm.2 |
Lrmp |
lymphoid-restricted membrane protein |
6 |
145115635, 145145474, 145121768 |
NM_001281980, NM_001281981, NM_008511, BC052909 NM_001281980, NM_001281981, NM_008511, BC052909 NM_001281980, NM_001281981, NM_008511, BC052909 NM_001281980, NM_001281981, NM_008511, BC052909 |
16970 |
33 |
immune system process protein binding nucleus nuclear envelope chromosome cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane cytoskeleton nucleus organization single fertilization microtubule binding membrane integral component of membrane integral component of endoplasmic reticulum membrane |
|
| TC0100003814.mm.2 |
Dtl |
denticleless E3 ubiquitin protein ligase |
1 |
-191537355 |
NM_029766 |
76843 |
33 |
protein polyubiquitination ubiquitin-protein transferase activity nucleus nucleoplasm chromosome nucleolus cytoplasm centrosome cytosol cytoskeleton DNA replication ubiquitin-dependent protein catabolic process protein monoubiquitination cellular response to DNA damage stimulus response to UV positive regulation of G2/M transition of mitotic cell cycle membrane translesion synthesis Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex positive regulation of protein catabolic process rhythmic process regulation of cell cycle signal transduction involved in G2 DNA damage checkpoint Cul4-RING E3 ubiquitin ligase complex |
|
| TC1700000402.mm.2 |
Pgap6 |
post-glycosylphosphatidylinositol attachment to proteins 6 |
17 |
26113315 |
NM_021793, BC005722 NM_021793, BC005722 |
60455 |
20 |
molecular_function phospholipase A2 activity lysosome plasma membrane integral component of plasma membrane biological_process membrane integral component of membrane hydrolase activity |
|
| TC0700004388.mm.2 |
Nsmce4a |
NSE4 homolog A, SMC5-SMC6 complex component |
7 |
-130532525 |
NM_001162855 |
67872 |
15 |
molecular_function nucleus nucleoplasm DNA repair nuclear body Smc5-Smc6 complex Smc5-Smc6 complex positive regulation of response to DNA damage stimulus |
|
| TC0200004207.mm.2 |
Ldlrad3 |
low density lipoprotein receptor class A domain containing 3 |
2 |
-101950200 |
NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 NM_178886, BC138177, BC138178, BC145174, XR_140510 |
241576 |
17 |
amyloid-beta binding plasma membrane receptor-mediated endocytosis membrane integral component of membrane regulation of protein processing |
|
| TC0500001251.mm.2 |
Pop5 |
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae) |
5 |
115235850 |
NM_026398, BC022670 NM_026398, BC022670 |
117109 |
19 |
ribonuclease MRP activity ribonuclease MRP complex ribonuclease MRP complex ribonuclease MRP complex tRNA 5'-leader removal ribonuclease P activity ribonuclease P activity ribonuclease P activity ribonuclease activity nucleus nucleolar ribonuclease P complex nucleolar ribonuclease P complex nucleolus rRNA processing rRNA processing tRNA processing tRNA processing RNA metabolic process hydrolase activity multimeric ribonuclease P complex ribonuclease P RNA binding |
03008 03013 |
| TC0400000133.mm.2 |
Tmem64 |
transmembrane protein 64 |
4 |
15265819 |
NM_181401, BC030341 NM_181401, BC030341 |
100201 |
20 |
protein binding endoplasmic reticulum membrane integral component of membrane regulation of ATPase activity positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of osteoclast differentiation positive regulation of bone resorption regulation of cytosolic calcium ion concentration negative regulation of canonical Wnt signaling pathway |
|
| TC0200001881.mm.2 |
Dut |
deoxyuridine triphosphatase |
2 |
125247247, 125247514 |
NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693 NM_001159646, NM_023595, BC019979, BC053693 |
110074 |
32 |
magnesium ion binding dUTP diphosphatase activity dUTP diphosphatase activity nucleus nucleoplasm cytoplasm mitochondrion cytosol dUMP biosynthetic process dUMP biosynthetic process receptor inhibitor activity pyrimidine deoxyribonucleotide binding identical protein binding peroxisome proliferator activated receptor binding regulation of protein-containing complex assembly dUTP catabolic process dUTP catabolic process |
00240 01100 |
| TC0900002047.mm.2 |
Ccdc15 |
coiled-coil domain containing 15 |
9 |
-37267463 |
NM_001081429 |
245902 |
12 |
molecular_function centrosome centrosome biological_process |
|
| TC0800000371.mm.2 |
Fut10 |
fucosyltransferase 10 |
8 |
31187330, 31187330 |
NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 NM_001012517, NM_001286422, NM_001286424, NM_001286425, NM_134161, BC030474, BC062113 |
171167 |
17 |
Golgi membrane nucleoplasm endoplasmic reticulum Golgi apparatus protein glycosylation fucosyltransferase activity membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups cerebral cortex radially oriented cell migration fucosylation alpha-(1->3)-fucosyltransferase activity alpha-(1->3)-fucosyltransferase activity neuronal stem cell population maintenance |
|
| TC0X00000429.mm.2 |
Utp14a |
UTP14A small subunit processome component |
X |
48256933 |
NM_028276, BC082590 NM_028276, BC082590 |
72554 |
22 |
nucleus nucleolus nucleolus cytosol rRNA processing small-subunit processome ribosome biogenesis |
03008 |
| TC1900000814.mm.2 |
Trub1 |
TruB pseudouridine (psi) synthase family member 1 |
19 |
57452905, 57452905 |
NM_028115, NM_029839, BC089592 NM_028115, NM_029839, BC089592 NM_028115, NM_029839, BC089592 |
72133 |
18 |
pseudouridine synthesis RNA binding nucleus cytoplasm mitochondrion cytosol RNA processing tRNA modification RNA modification pseudouridine synthase activity pseudouridine synthase activity isomerase activity mRNA pseudouridine synthesis mRNA pseudouridine synthesis |
|
| TC1400001152.mm.2 |
Bora |
bora, aurora kinase A activator |
14 |
99046376 |
NM_175265, BC052183 NM_175265, BC052183 |
77744 |
19 |
nucleus cytoplasm cell cycle regulation of mitotic nuclear division regulation of mitotic nuclear division protein kinase binding protein kinase binding activation of protein kinase activity regulation of protein localization cell division regulation of mitotic spindle organization regulation of mitotic spindle organization meiotic spindle |
|
| TC0500003418.mm.2 |
Cux1 |
cut-like homeobox 1 |
5 |
-136248134, -136266409, -136266409, -136248134 |
NM_009986, NM_198602, BC090847 NM_009986, NM_198602, BC090847 NM_009986, NM_198602, BC090847 |
13047 |
445 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific kidney development DNA binding chromatin binding nucleus nucleus cytoplasm Golgi apparatus regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II intra-Golgi vesicle-mediated transport multicellular organism development membrane integral component of membrane integral component of Golgi membrane lung development inner ear auditory receptor cell differentiation neuron projection sequence-specific DNA binding positive regulation of dendrite morphogenesis |
|
| TC0X00001766.mm.2 |
Clcn5 |
chloride channel, voltage-sensitive 5 |
X |
-7158411, -7158411 |
NM_001243762, NM_016691, BC036347 NM_001243762, NM_016691, BC036347 NM_001243762, NM_016691, BC036347 |
12728 |
71 |
nucleotide binding voltage-gated chloride channel activity voltage-gated chloride channel activity chloride channel activity ATP binding endosome endosome early endosome Golgi apparatus Golgi apparatus cytosol plasma membrane integral component of plasma membrane ion transport chloride transport endocytosis synaptic vesicle antiporter activity solute:proton antiporter activity membrane integral component of membrane identical protein binding apical part of cell apical part of cell transmembrane transport |
|
| TC0100001656.mm.2 |
Exo1 |
exonuclease 1 |
1 |
175880777 |
NM_012012, BC006671 NM_012012, BC006671 |
26909 |
51 |
immune system process humoral immune response mediated by circulating immunoglobulin DNA binding chromatin binding catalytic activity nuclease activity endonuclease activity exonuclease activity nucleus nucleus nucleoplasm plasma membrane nucleobase-containing compound metabolic process DNA repair mismatch repair mismatch repair DNA recombination DNA recombination cellular response to DNA damage stimulus 5'-3' exonuclease activity somatic hypermutation of immunoglobulin genes nuclear body hydrolase activity hydrolase activity, acting on ester bonds 5'-flap endonuclease activity 5'-3' exodeoxyribonuclease activity 5'-3' exodeoxyribonuclease activity single-stranded DNA 5'-3' exodeoxyribonuclease activity isotype switching metal ion binding flap endonuclease activity meiotic cell cycle double-stranded DNA 5'-3' exodeoxyribonuclease activity |
03430 |
| TC0800002596.mm.2 |
Rnaseh2a |
ribonuclease H2, large subunit |
8 |
-84957666, -84956609 |
NM_027187, BC029252, BC038158 NM_027187, BC029252, BC038158 NM_027187, BC029252, BC038158 |
69724 |
24 |
nucleic acid binding RNA binding nuclease activity endonuclease activity RNA-DNA hybrid ribonuclease activity RNA-DNA hybrid ribonuclease activity nucleus nucleoplasm cytosol mismatch repair mismatch repair mismatch repair RNA catabolic process RNA metabolic process hydrolase activity ribonuclease H2 complex ribonuclease H2 complex ribonuclease H2 complex DNA replication, removal of RNA primer metal ion binding |
03030 |
| TC1300002617.mm.2 |
Ipo11 |
importin 11 |
13 |
-106794438 |
NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943 NM_029665, BC029746, BC031900, XM_003084943 |
76582 |
23 |
protein binding nucleus nuclear envelope nucleoplasm cytoplasm cytosol cytosol protein import into nucleus ribosomal protein import into nucleus intracellular protein transport protein transport small GTPase binding nuclear import signal receptor activity |
|
| TC1300000671.mm.2 |
Ddx46 |
DEAD box helicase 46 |
13 |
55634998 |
NM_001282055, BC026492, BC092240, NM_145975 NM_001282055, BC026492, BC092240, NM_145975 NM_001282055, BC026492, BC092240, NM_145975 NM_001282055, BC026492, BC092240, NM_145975 |
212880 |
26 |
nucleotide binding mRNA splicing, via spliceosome fibrillar center nucleic acid binding RNA binding helicase activity ATP binding nucleus nucleus mRNA processing RNA splicing membrane nuclear speck hydrolase activity |
03040 |
| TC0200005331.mm.2 |
|
|
|
|
XR_140551 |
|
|
|
|
| TC0200002579.mm.2 |
Ddx27 |
DEAD box helicase 27 |
2 |
167015312 |
NM_153065, BC011321 NM_153065, BC011321 |
228889 |
30 |
nucleotide binding nucleic acid binding helicase activity ATP binding nucleus chromosome nucleolus nucleolus rRNA processing hydrolase activity ribosome biogenesis |
|
| TC0900003168.mm.2 |
Crtap |
cartilage associated protein |
9 |
-114375130 |
NM_019922, BC049890 NM_019922, BC049890 |
56693 |
28 |
collagen binding extracellular region extracellular space endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum spermatogenesis peptidyl-proline hydroxylation to 3-hydroxy-L-proline peptidyl-proline hydroxylation to 3-hydroxy-L-proline collagen fibril organization protein stabilization negative regulation of post-translational protein modification |
|
| TC1000000191.mm.2 |
Slc18b1 |
solute carrier family 18, subfamily B, member 1 |
10 |
23796985 |
NM_183116 |
76306 |
17 |
membrane integral component of membrane transmembrane transporter activity |
|
| TC0800001390.mm.2 |
Cenpn |
centromere protein N |
8 |
116921739 |
NM_028131, BC058243 NM_028131, BC058243 |
72155 |
14 |
chromosome, centromeric region kinetochore molecular_function nucleus nucleoplasm chromosome chromosome segregation kinetochore assembly |
|
| TC0400000085.mm.2 |
Ccne2 |
cyclin E2 |
4 |
11191708, 11191350 |
NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727 NM_001037134, NM_001282943, NM_009830, BC053727 |
12448 |
79 |
regulation of cyclin-dependent protein serine/threonine kinase activity G1/S transition of mitotic cell cycle cyclin-dependent protein kinase holoenzyme complex telomere maintenance nucleus cytoplasm centrosome DNA replication initiation cell cycle homologous chromosome pairing at meiosis cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein serine/threonine kinase regulator activity protein kinase binding mitotic cell cycle phase transition cell division regulation of cell cycle chromosome organization involved in meiotic cell cycle cyclin E1-CDK2 complex cyclin E2-CDK2 complex cyclin E2-CDK2 complex cyclin E2-CDK2 complex regulation of cellular protein localization |
04110 04114 04115 05200 05215 05222 |
| TC1600001254.mm.2 |
Mcm4 |
minichromosome maintenance complex component 4 |
16 |
-15623896 |
NM_008565, BC013094 NM_008565, BC013094 |
17217 |
66 |
nucleotide binding double-strand break repair via break-induced replication DNA binding DNA helicase activity DNA helicase activity DNA replication origin binding single-stranded DNA binding single-stranded DNA binding helicase activity protein binding ATP binding nucleus nucleoplasm chromosome DNA replication pre-replicative complex assembly involved in nuclear cell cycle DNA replication DNA unwinding involved in DNA replication DNA unwinding involved in DNA replication DNA replication initiation DNA strand elongation involved in DNA replication cell cycle hydrolase activity MCM complex MCM complex mitotic DNA replication initiation |
03030 04110 |
| TC1900001428.mm.2 |
Pank1 |
pantothenate kinase 1 |
19 |
-34806935, -34806935 |
NM_001114339, NM_023792, BC023496 NM_001114339, NM_023792, BC023496 NM_001114339, NM_023792, BC023496 |
75735 |
33 |
nucleotide binding pantothenate kinase activity pantothenate kinase activity pantothenate kinase activity ATP binding nucleus nucleus nucleus cytosol cytosol cytosol coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process kinase activity phosphorylation transferase activity clathrin coat protein homodimerization activity recycling endosome cell periphery acetyl-CoA binding |
00770 01100 |
| TC0200001002.mm.2 |
Nostrin |
nitric oxide synthase trafficker |
2 |
69135799 |
NM_181547, BC069942 NM_181547, BC069942 |
329416 |
17 |
DNA binding protein binding nucleus cytoplasm cytoskeleton plasma membrane endocytosis signal transduction membrane cytoplasmic vesicle negative regulation of transcription, DNA-templated |
|
| TC0500002232.mm.2 |
Zfyve28 |
zinc finger, FYVE domain containing 28 |
5 |
-34194893 |
NM_001015039, BC139050, BC139051 NM_001015039, BC139050, BC139051 NM_001015039, BC139050, BC139051 |
231125 |
20 |
cytoplasm endosome cytosol negative regulation of epidermal growth factor-activated receptor activity negative regulation of epidermal growth factor-activated receptor activity membrane early endosome membrane early endosome membrane phosphatidylinositol-3-phosphate binding negative regulation of epidermal growth factor receptor signaling pathway metal ion binding |
|
| TC0100000267.mm.2 |
Lipt1 |
lipoyltransferase 1 |
1 |
37872218, 37872349, 37871737 |
NM_001037918, BC019519 NM_001037918, BC019519 |
623661 |
16 |
cytoplasm mitochondrion mitochondrion cellular protein modification process protein lipoylation transferase activity transferase activity, transferring acyl groups lipoyltransferase activity |
00785 01100 |
| TC0300001587.mm.2 |
Depdc1a |
DEP domain containing 1a |
3 |
159495432 |
NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934 NM_001172092, NM_001172093, NM_029523, BC023934 |
76131 |
12 |
GTPase activator activity nucleus nucleus signal transduction transcription repressor complex transcription repressor complex intracellular signal transduction negative regulation of transcription, DNA-templated |
|
| MG-1-pos-10343924_st |
|
|
|
|
|
|
|
|
|
| TC1200001742.mm.2 |
Egln3 |
egl-9 family hypoxia-inducible factor 3 |
12 |
-54178980 |
NM_028133, BC044926, BC058278, BC069893, BC022961 NM_028133, BC044926, BC058278, BC069893, BC022961 NM_028133, BC044926, BC058278, BC069893, BC022961 NM_028133, BC044926, BC058278, BC069893, BC022961 NM_028133, BC044926, BC058278, BC069893, BC022961 |
112407 |
104 |
iron ion binding nucleus nucleus cytoplasm cytoplasm cytosol apoptotic process cellular response to DNA damage stimulus ferrous iron binding oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2-oxoglutarate-dependent dioxygenase activity protein hydroxylation peptidyl-proline hydroxylation to 4-hydroxy-L-proline peptidyl-proline hydroxylation to 4-hydroxy-L-proline L-ascorbic acid binding peptidyl-proline dioxygenase activity peptidyl-proline dioxygenase activity peptidyl-proline 4-dioxygenase activity peptidyl-proline 4-dioxygenase activity regulation of cell population proliferation regulation of cell population proliferation regulation of neuron apoptotic process metal ion binding dioxygenase activity cellular response to hypoxia cellular response to leukemia inhibitory factor |
05200 05211 |
| TC0100001548.mm.2 |
Tmco1 |
transmembrane and coiled-coil domains 1 |
1 |
167308669 |
NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098 NM_001039483, BC011457, BC019761, BC020098 |
68944 |
31 |
calcium channel activity calcium channel activity cytoplasm endoplasmic reticulum endoplasmic reticulum Golgi apparatus ion transport calcium ion transport cellular calcium ion homeostasis ER overload response membrane integral component of membrane integral component of endoplasmic reticulum membrane endoplasmic reticulum calcium ion homeostasis endoplasmic reticulum calcium ion homeostasis endoplasmic reticulum calcium ion homeostasis calcium ion transmembrane transport calcium ion transmembrane transport |
|
| TC0600000608.mm.2 |
Cbx3 |
chromobox 3 |
6 |
51471251, 51470615 |
NM_007624, BC018354, BC059831, BC108370, BC110376 NM_007624, BC018354, BC059831, BC108370, BC110376 NM_007624, BC018354, BC059831, BC108370, BC110376 NM_007624, BC018354, BC059831, BC108370, BC110376 NM_007624, BC018354, BC059831, BC108370, BC110376 |
12417 |
103 |
chromosome, centromeric region condensed chromosome, centromeric region chromatin chromatin euchromatin heterochromatin heterochromatin transcription regulatory region sequence-specific DNA binding protein binding nucleus nucleus nuclear envelope nucleoplasm pericentric heterochromatin spindle chromatin organization cellular response to DNA damage stimulus transcription factor binding chromocenter enzyme binding protein domain specific binding senescence-associated heterochromatin focus identical protein binding negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated rhythmic process RNA polymerase II transcription regulator complex site of DNA damage histone methyltransferase binding |
|
| TC1300001806.mm.2 |
Lyrm4 |
LYR motif containing 4 |
13 |
-35978796 |
NM_201358, BC034664, BC080772 NM_201358, BC034664, BC080772 NM_201358, BC034664, BC080772 |
380840 |
17 |
molecular_function nucleus mitochondrion mitochondrion iron-sulfur cluster assembly nuclear body L-cysteine desulfurase complex |
|
| TC0100000829.mm.2 |
Dgkd |
diacylglycerol kinase, delta |
1 |
87853286 |
NM_177646 |
227333 |
35 |
nucleotide binding NAD+ kinase activity diacylglycerol kinase activity diacylglycerol kinase activity diacylglycerol kinase activity ATP binding cytoplasm cytosol plasma membrane clathrin-coated pit phosphatidic acid biosynthetic process endocytosis signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway response to organic substance protein transport membrane kinase activity phosphorylation transferase activity kinase binding cytoplasmic vesicle intracellular signal transduction identical protein binding protein homodimerization activity positive regulation of epidermal growth factor receptor signaling pathway diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process lipid phosphorylation lipid phosphorylation lipid phosphorylation metal ion binding protein heterodimerization activity negative regulation of protein kinase C signaling positive regulation of clathrin-dependent endocytosis |
00561 00564 01100 04070 |
| TC1200001348.mm.2 |
Efr3b |
EFR3 homolog B |
12 |
-3962553 |
NM_001082483, BC147643, BC157968 NM_001082483, BC147643, BC157968 NM_001082483, BC147643, BC157968 |
668212 |
14 |
molecular_function cytoplasm cytosol plasma membrane plasma membrane actin cytoskeleton membrane phosphatidylinositol phosphorylation protein localization to plasma membrane protein localization to plasma membrane |
|
| TC0100001271.mm.2 |
Kif14 |
kinesin family member 14 |
1 |
136467847 |
NM_001287179, BC158132, NM_001081258 NM_001287179, BC158132, NM_001081258 NM_001287179, BC158132, NM_001081258 |
381293 |
25 |
nucleotide binding regulation of cell growth microtubule motor activity ATP binding nucleus cytoplasm cytosol cytoskeleton kinesin complex microtubule microtubule plasma membrane microtubule-based movement mitotic metaphase plate congression microtubule binding microtubule binding positive regulation of cell population proliferation ATP-dependent microtubule motor activity, plus-end-directed regulation of G2/M transition of mitotic cell cycle tubulin binding ATPase activity ATPase activity protein kinase binding cerebellar granular layer structural organization cerebellar Purkinje cell layer structural organization cerebellar cortex development hippocampus development olfactory bulb development cell proliferation in forebrain cerebral cortex development regulation of cell adhesion PDZ domain binding regulation of cell migration midbody SCF-dependent proteasomal ubiquitin-dependent protein catabolic process regulation of myelination activation of protein kinase activity positive regulation of cytokinesis regulation of Rap protein signal transduction negative regulation of integrin activation substrate adhesion-dependent cell spreading negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process regulation of neuron apoptotic process negative regulation of neuron apoptotic process establishment of protein localization spindle midzone cell division Flemming body regulation of cell maturation regulation of G1/S transition of mitotic cell cycle |
|
| TC0400000567.mm.2 |
Smc2 |
structural maintenance of chromosomes 2 |
4 |
52439220 |
NM_008017, BC094380 NM_008017, BC094380 |
14211 |
37 |
single strand break repair nucleotide binding nuclear chromosome condensed chromosome condensed chromosome condensin complex condensin complex condensin complex condensin complex chromatin binding single-stranded DNA binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome nucleolus cytoplasm cell cycle mitotic chromosome condensation meiotic chromosome condensation chromosome condensation meiotic chromosome segregation chromosome organization cell division kinetochore organization |
|
| TC1000001204.mm.2 |
Galnt4 |
polypeptide N-acetylgalactosaminyltransferase 4 |
10 |
99108134 |
NM_015737, BC057882 NM_015737, BC057882 |
14426 |
21 |
polypeptide N-acetylgalactosaminyltransferase activity Golgi apparatus Golgi apparatus membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine protein O-linked glycosylation via threonine manganese ion binding carbohydrate binding metal ion binding perinuclear region of cytoplasm |
00512 01100 |
| TC1300001641.mm.2 |
Hfe |
homeostatic iron regulator |
13 |
-23702033 |
NM_010424, BC116744, BC116746 NM_010424, BC116744, BC116746 NM_010424, BC116744, BC116746 |
15216 |
179 |
negative regulation of T cell antigen processing and presentation negative regulation of T cell cytokine production signaling receptor binding extracellular space extracellular space nucleoplasm early endosome plasma membrane ion transport cellular iron ion homeostasis external side of plasma membrane external side of plasma membrane response to iron ion positive regulation of gene expression positive regulation of pathway-restricted SMAD protein phosphorylation membrane integral component of membrane BMP signaling pathway beta-2-microglobulin binding cytoplasmic vesicle positive regulation of protein binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process regulation of iron ion transport regulation of iron ion transport co-receptor binding hormone biosynthetic process apical part of cell basal part of cell positive regulation of receptor-mediated endocytosis perinuclear region of cytoplasm recycling endosome iron ion homeostasis iron ion homeostasis multicellular organismal iron ion homeostasis cellular response to iron ion positive regulation of peptide hormone secretion iron ion import across plasma membrane negative regulation of receptor binding positive regulation of receptor binding negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I positive regulation of ferrous iron binding positive regulation of transferrin receptor binding terminal web transferrin receptor binding transferrin receptor binding transferrin receptor binding response to iron ion starvation HFE-transferrin receptor complex HFE-transferrin receptor complex regulation of protein localization to cell surface negative regulation of ubiquitin-dependent protein catabolic process negative regulation of ubiquitin-dependent protein catabolic process negative regulation of signaling receptor activity positive regulation of signaling receptor activity negative regulation of CD8-positive, alpha-beta T cell activation |
|
| TC1100001586.mm.2 |
Cdc6 |
cell division cycle 6 |
11 |
98907800, 98908150 |
NM_001025779, NM_011799, BC052434 NM_001025779, NM_011799, BC052434 NM_001025779, NM_011799, BC052434 |
23834 |
42 |
nucleotide binding mitotic cell cycle spindle pole chromatin binding DNA replication origin binding ATP binding nucleus nucleus nucleoplasm cytoplasm spindle cytosol DNA replication DNA replication initiation cell cycle kinase binding regulation of mitotic metaphase/anaphase transition positive regulation of cytokinesis mitotic DNA replication checkpoint intercellular bridge positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of fibroblast proliferation spindle midzone cell division positive regulation of chromosome segregation mitotic spindle |
04110 |
| TC1600000503.mm.2 |
Ccdc58 |
coiled-coil domain containing 58 |
16 |
36071659, 36081274 |
NM_001159421, NM_001159422, NM_198645, BC024862 NM_001159421, NM_001159422, NM_198645, BC024862 NM_001159421, NM_001159422, NM_198645, BC024862 NM_001159421, NM_001159422, NM_198645, BC024862 |
381045 |
19 |
molecular_function mitochondrion mitochondrion biological_process |
|
| TC0100002314.mm.2 |
Gls |
glutaminase |
1 |
-52185280, -52163449 |
NM_001081081, NM_001113383 NM_001081081, NM_001113383 |
14660 |
82 |
suckling behavior regulation of respiratory gaseous exchange by nervous system process glutaminase activity glutaminase activity glutaminase activity glutaminase activity protein binding cytoplasm mitochondrion glutamate biosynthetic process glutamate biosynthetic process glutamate biosynthetic process glutamine metabolic process glutamine catabolic process glutamine catabolic process glutamine catabolic process glutamine catabolic process chemical synaptic transmission hydrolase activity identical protein binding protein homotetramerization protein homotetramerization glutamate homeostasis |
00250 00330 00471 00910 01100 04964 |
| TC1800000344.mm.2 |
Wdr55 |
WD repeat domain 55 |
18 |
36760221 |
NM_026464, BC131932, BC131934 NM_026464, BC131932, BC131934 NM_026464, BC131932, BC131934 |
67936 |
17 |
molecular_function nucleus nucleoplasm nucleolus nucleolus cytoplasm rRNA processing rRNA processing |
|
| TC1500001927.mm.2 |
Rangap1 |
RAN GTPase activating protein 1 |
15 |
-81704247 |
NM_001146174, NM_011241, BC014855, BC052862, BC066213, BC071200 NM_001146174, NM_011241, BC014855, BC052862, BC066213, BC071200 NM_001146174, NM_011241, BC014855, BC052862, BC066213, BC071200 NM_001146174, NM_011241, BC014855, BC052862, BC066213, BC071200 NM_001146174, NM_011241, BC014855, BC052862, BC066213, BC071200 NM_001146174, NM_011241, BC014855, BC052862, BC066213, BC071200 |
19387 |
54 |
chromosome, centromeric region kinetochore RNA binding GTPase activator activity nucleus nuclear envelope nuclear pore chromosome cytoplasm cytoplasm cytosol cytoskeleton signal transduction aggresome dendrite small GTPase binding ubiquitin protein ligase binding nuclear membrane intracellular membrane-bounded organelle nuclear pore cytoplasmic filaments negative regulation of protein export from nucleus perinuclear region of cytoplasm perinuclear region of cytoplasm cellular response to peptide hormone stimulus mitotic spindle activation of GTPase activity axon cytoplasm cytoplasmic periphery of the nuclear pore complex |
03013 |
| TC0500001066.mm.2 |
Cdc7 |
cell division cycle 7 (S. cerevisiae) |
5 |
106964321, 106964560 |
NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 NM_001271566, NM_001271567, NM_001271568, NM_009863, BC072666, BC080702 |
12545 |
32 |
nucleotide binding double-strand break repair via break-induced replication protein kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm protein phosphorylation cell cycle positive regulation of cell population proliferation positive regulation of nuclear cell cycle DNA replication positive regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell cycle phase transition intercellular bridge metal ion binding cell division mitotic spindle |
04110 |
| TSUnmapped00000020.mm.2 |
Snx29 |
sorting nexin 29 |
16 |
11322903, 11405647 |
NM_001290148 |
74478 |
15 |
molecular_function biological_process phosphatidylinositol binding |
|
| TC0500001512.mm.2 |
|
|
|
|
NM_009838, NR_003681, BC018459, BC069917, BC094352 NM_009838, NR_003681, BC018459, BC069917, BC094352 NM_009838, NR_003681, BC018459, BC069917, BC094352 NM_009838, NR_003681, BC018459, BC069917, BC094352 NM_009838, NR_003681, BC018459, BC069917, BC094352 |
|
|
nucleotide binding acrosomal vesicle zona pellucida receptor complex molecular_function protein binding ATP binding cellular_component cytoplasm cytosol chaperonin-containing T-complex chaperonin-containing T-complex chaperonin-containing T-complex microtubule protein folding protein folding binding of sperm to zona pellucida biological_process positive regulation of telomere maintenance via telomerase protein folding chaperone cell body protein stabilization unfolded protein binding WD40-repeat domain binding toxin transport positive regulation of establishment of protein localization to telomere |
|
| TC1700001987.mm.2 |
Mrps18b |
mitochondrial ribosomal protein S18B |
17 |
-35910379 |
NM_025878, BC021752 NM_025878, BC021752 |
66973 |
27 |
structural constituent of ribosome intracellular anatomical structure nucleoplasm mitochondrion mitochondrion mitochondrion mitochondrial small ribosomal subunit mitochondrial small ribosomal subunit ribosome translation cell junction mitochondrial translation |
|
| TC1600001277.mm.2 |
2610318N02Rik |
RIKEN cDNA 2610318N02 gene |
16 |
-17113397 |
NM_183287, BC039993 NM_183287, BC039993 |
70458 |
15 |
molecular_function cellular_component biological_process |
|
| TC1900000491.mm.2 |
Lipn |
lipase, family member N |
19 |
34067357 |
NM_027340 |
70166 |
12 |
extracellular region lipid metabolic process lipid catabolic process hydrolase activity hydrolase activity, acting on ester bonds intracellular membrane-bounded organelle |
|
| MG-1-neg-10341763_st |
|
|
|
|
|
|
|
|
|
| TC0X00002689.mm.2 |
Ophn1 |
oligophrenin 1 |
X |
-98554279, -98873725 |
NM_052976, BC004845 NM_052976, BC004845 |
94190 |
39 |
actin binding GTPase activator activity GTPase activator activity protein binding phospholipid binding cytoplasm cytoplasm endocytosis signal transduction nervous system development actin cytoskeleton actin cytoskeleton cerebellar granule cell differentiation cerebral cortex neuron differentiation actin cytoskeleton organization actin cytoskeleton organization cell junction regulation of endocytosis regulation of endocytosis neuron differentiation dendrite neuron projection development cell junction assembly regulation of Rho protein signal transduction ionotropic glutamate receptor binding cell projection terminal bouton terminal bouton dendritic spine dendritic spine establishment of epithelial cell apical/basal polarity synapse synaptic vesicle endocytosis synaptic vesicle endocytosis synaptic vesicle endocytosis cell morphogenesis involved in neuron differentiation regulation of synaptic transmission, glutamatergic regulation of synaptic transmission, glutamatergic maintenance of postsynaptic specialization structure glutamatergic synapse regulation of postsynaptic neurotransmitter receptor internalization negative regulation of proteasomal protein catabolic process negative regulation of proteasomal protein catabolic process |
|
| TC1700002794.mm.2 |
|
|
|
|
NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 NM_001123368, NM_001123367, BC061136, BC131981, BC131983 |
|
|
molecular_function protein binding cellular_component cytosol cytoplasmic dynein complex microtubule-based movement biological_process extrinsic component of membrane sperm flagellum |
|
| TC0700002004.mm.2 |
Mtg1 |
mitochondrial ribosome-associated GTPase 1 |
7 |
140137563 |
NM_199301, BC027306 NM_199301, BC027306 |
212508 |
16 |
nucleotide binding GTPase activity GTPase activity GTP binding mitochondrion mitochondrion mitochondrial inner membrane mitochondrial matrix mitochondrial ribosome regulation of translation membrane regulation of respiratory system process regulation of mitochondrial translation |
|
| TC0X00001674.mm.2 |
Fancb |
Fanconi anemia, complementation group B |
X |
164980591 |
NM_001146081, NM_175027, BC083151 NM_001146081, NM_175027, BC083151 NM_001146081, NM_175027, BC083151 |
237211 |
17 |
molecular_function nucleus DNA repair cellular response to DNA damage stimulus cellular response to drug cellular response to drug interstrand cross-link repair Fanconi anaemia nuclear complex Fanconi anaemia nuclear complex cellular response to camptothecin positive regulation of double-strand break repair via homologous recombination positive regulation of double-strand break repair via homologous recombination replication-born double-strand break repair via sister chromatid exchange replication-born double-strand break repair via sister chromatid exchange negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination |
|
| TC0300000412.mm.2 |
Alg5 |
asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase) |
3 |
54735538 |
NM_025442, BC027160 NM_025442, BC027160 |
66248 |
19 |
dolichyl-phosphate beta-glucosyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane protein N-linked glycosylation determination of left/right symmetry membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups |
00510 01100 |
| TC1200001597.mm.2 |
Bcap29 |
B cell receptor associated protein 29 |
12 |
-31595353, -31595353 |
NM_001164090, NM_007530, BC003303, BC021661 NM_001164090, NM_007530, BC003303, BC021661 NM_001164090, NM_007530, BC003303, BC021661 NM_001164090, NM_007530, BC003303, BC021661 |
12033 |
24 |
endoplasmic reticulum endoplasmic reticulum membrane intracellular protein transport endoplasmic reticulum to Golgi vesicle-mediated transport endoplasmic reticulum to Golgi vesicle-mediated transport apoptotic process protein transport membrane integral component of membrane vesicle-mediated transport protein localization to endoplasmic reticulum exit site protein localization to endoplasmic reticulum exit site |
|
| TC1400000501.mm.2 |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
14 |
46760540 |
NM_028222, BC049694 NM_028222, BC049694 |
72391 |
17 |
phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity protein binding cytoplasm cytosol cellular response to DNA damage stimulus cell cycle cell cycle arrest cell cycle arrest dephosphorylation hydrolase activity phosphatase activity perinuclear region of cytoplasm |
|
| TC0800002339.mm.2 |
Psd3 |
pleckstrin and Sec7 domain containing 3 |
8 |
-67689081, -67689081, -67689081 |
NM_027626, NM_030263, NM_177698 NM_027626, NM_030263, NM_177698 NM_027626, NM_030263, NM_177698 |
234353 |
22 |
guanyl-nucleotide exchange factor activity plasma membrane membrane cell junction ARF protein signal transduction regulation of ARF protein signal transduction ruffle membrane ruffle membrane cell projection synapse |
04144 |
| TC1600002094.mm.2 |
Rcan1 |
regulator of calcineurin 1 |
16 |
-92391950, -92391950 |
NM_001081549, NM_019466, BC013551 NM_001081549, NM_019466, BC013551 NM_001081549, NM_019466, BC013551 |
54720 |
113 |
response to ischemia nucleic acid binding protein binding nucleus nucleus cytoplasm cytoplasm response to stress response to stress response to oxidative stress short-term memory calcium-dependent protein serine/threonine phosphatase regulator activity calcium-mediated signaling locomotion involved in locomotory behavior calcineurin-NFAT signaling cascade calcineurin-NFAT signaling cascade identical protein binding regulation of phosphoprotein phosphatase activity skeletal muscle fiber development negative regulation of calcineurin-NFAT signaling cascade |
|
| TC0600003003.mm.2 |
Ankrd26 |
ankyrin repeat domain 26 |
6 |
-118501299 |
NM_001081112 |
232339 |
22 |
protein binding cytoplasm centrosome actin cytoskeleton regulation of lipid metabolic process regulation of fatty acid metabolic process negative regulation of multicellular organism growth glucose homeostasis negative regulation of fat cell differentiation negative regulation of organ growth negative regulation of insulin receptor signaling pathway regulation of feeding behavior negative regulation of ERK1 and ERK2 cascade |
|
| TC1300002654.mm.2 |
Gapt |
Grb2-binding adaptor, transmembrane |
13 |
-110352614 |
NM_177713, BC116629, BC118005 NM_177713, BC116629, BC118005 NM_177713, BC116629, BC118005 |
238875 |
14 |
B cell homeostasis B cell homeostasis B cell proliferation involved in immune response B cell proliferation involved in immune response immunoglobulin production involved in immunoglobulin-mediated immune response immunoglobulin production involved in immunoglobulin-mediated immune response Golgi apparatus plasma membrane membrane integral component of membrane B cell activation intracellular membrane-bounded organelle |
|
| TC0900001459.mm.2 |
Scap |
SREBF chaperone |
9 |
110333355, 110333287 |
NM_001001144, NM_001103162, BC070437, BC072633 NM_001001144, NM_001103162, BC070437, BC072633 NM_001001144, NM_001103162, BC070437, BC072633 NM_001001144, NM_001103162, BC070437, BC072633 |
235623 |
64 |
Golgi membrane response to hypoxia protein binding endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus lipid metabolic process immune response steroid metabolic process cholesterol metabolic process lipid binding cholesterol binding membrane integral component of membrane regulation of fatty acid metabolic process cytoplasmic vesicle response to insulin SREBP signaling pathway sterol binding protein-containing complex regulation of fatty acid biosynthetic process intracellular membrane-bounded organelle cellular lipid metabolic process protein-containing complex binding regulation of cholesterol biosynthetic process positive regulation of cholesterol biosynthetic process |
|
| TC0100002844.mm.2 |
St8sia4 |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
1 |
-95587681, -95627242 |
NM_001159745, NM_009183, BC060112 NM_001159745, NM_009183, BC060112 NM_001159745, NM_009183, BC060112 |
20452 |
59 |
ganglioside biosynthetic process alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation N-glycan processing N-glycan processing sialyltransferase activity oligosaccharide metabolic process oligosaccharide metabolic process membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups |
|
| TC0100002308.mm.2 |
Myo1b |
myosin IB |
1 |
-51749757 |
NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786 NM_001161817, NM_010863, BC046300, BC054786 |
17912 |
41 |
microfilament motor activity microfilament motor activity nucleotide binding motor activity actin binding calmodulin binding ATP binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm cytoplasm early endosome actin filament plasma membrane plasma membrane microvillus brush border brush border brush border post-Golgi vesicle-mediated transport actin filament organization actin filament organization endosome membrane actin cytoskeleton myosin complex actin filament-based movement vesicle transport along actin filament filopodium actin-dependent ATPase activity actin-dependent ATPase activity vesicle trans-Golgi network membrane transferrin transport apical part of cell perinuclear region of cytoplasm actin filament binding actin filament binding actin filament bundle assembly cell periphery |
|
| TC1500001568.mm.2 |
Atad2 |
ATPase family, AAA domain containing 2 |
15 |
-58094046 |
NM_027435 |
70472 |
24 |
nucleotide binding chromatin binding protein binding ATP binding nucleus nucleoplasm chromatin organization regulation of transcription, DNA-templated hydrolase activity ATPase activity ATPase activity negative regulation of chromatin silencing histone binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II |
|
| MG-1-pos-10341530_st |
|
|
|
|
|
|
|
|
|
| TC1100004233.mm.2 |
Fasn |
fatty acid synthase |
11 |
-120805957 |
NM_007988, BC046513 NM_007988, BC046513 |
14104 |
153 |
glandular epithelial cell development catalytic activity fatty acid synthase activity fatty acid synthase activity fatty acid synthase activity [acyl-carrier-protein] S-acetyltransferase activity [acyl-carrier-protein] S-malonyltransferase activity 3-oxoacyl-[acyl-carrier-protein] synthase activity 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity oleoyl-[acyl-carrier-protein] hydrolase activity cytoplasm mitochondrion Golgi apparatus cytosol plasma membrane acetyl-CoA metabolic process lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process fatty acid biosynthetic process metabolic process ether lipid biosynthetic process biosynthetic process tissue development myristoyl-[acyl-carrier-protein] hydrolase activity palmitoyl-[acyl-carrier-protein] hydrolase activity acyl-[acyl-carrier-protein] hydrolase activity oxidoreductase activity transferase activity hydrolase activity hydrolase activity, acting on ester bonds lyase activity 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity neutrophil differentiation monocyte differentiation mammary gland development phosphopantetheine binding glycogen granule identical protein binding enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity cellular response to interleukin-4 establishment of endothelial intestinal barrier 3-oxo-glutaryl-[acp] methyl ester reductase activity 3-oxo-pimeloyl-[acp] methyl ester reductase activity |
00061 01100 04910 |
| TC0700001402.mm.2 |
Pgm2l1 |
phosphoglucomutase 2-like 1 |
7 |
100227606 |
NM_027629, BC032150, BC076571 NM_027629, BC032150, BC076571 NM_027629, BC032150, BC076571 |
70974 |
17 |
carbohydrate metabolic process glucose metabolic process transferase activity isomerase activity intramolecular transferase activity, phosphotransferases metal ion binding glucose-1,6-bisphosphate synthase activity glucose-1,6-bisphosphate synthase activity organic substance metabolic process |
00500 |
| TC0600003342.mm.2 |
Eps8 |
epidermal growth factor receptor pathway substrate 8 |
6 |
-137477244, -137477244, -137477244 |
NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 NM_001271587, NM_001271588, NM_001271589, NM_001271595, NM_007945, BC016890 |
13860 |
73 |
actin binding actin binding protein binding cytoplasm plasma membrane brush border cell cortex Rho protein signal transduction adult locomotory behavior regulation of cell shape exit from mitosis postsynaptic density postsynaptic density membrane Rac protein signal transduction NMDA selective glutamate receptor complex cell junction regulation of actin filament length small GTPase binding actin cytoskeleton reorganization stereocilium stereocilium bundle stereocilium tip ruffle membrane ruffle membrane regulation of Rho protein signal transduction signaling adaptor activity dendritic cell migration cell projection neuron projection synapse behavioral response to ethanol barbed-end actin filament capping barbed-end actin filament capping actin filament bundle assembly actin filament bundle assembly actin filament bundle assembly actin crosslink formation actin crosslink formation actin polymerization-dependent cell motility glutamatergic synapse glutamatergic synapse glutamatergic synapse regulation of postsynaptic membrane neurotransmitter receptor levels regulation of postsynaptic membrane neurotransmitter receptor levels regulation of postsynaptic membrane neurotransmitter receptor levels positive regulation of ruffle assembly cellular response to leukemia inhibitory factor |
|
| TC1000000656.mm.2 |
Rhobtb1 |
Rho-related BTB domain containing 1 |
10 |
69212656, 69208551, 69213193 |
NM_001081347, NM_001252636, NM_001252637, NM_001252638, BC099973, BC137646, BC137647, BC144800 NM_001081347, NM_001252636, NM_001252637, NM_001252638, BC099973, BC137646, BC137647, BC144800 NM_001081347, NM_001252636, NM_001252637, NM_001252638, BC099973, BC137646, BC137647, BC144800 NM_001081347, NM_001252636, NM_001252637, NM_001252638, BC099973, BC137646, BC137647, BC144800 NM_001081347, NM_001252636, NM_001252637, NM_001252638, BC099973, BC137646, BC137647, BC144800 NM_001081347, NM_001252636, NM_001252637, NM_001252638, BC099973, BC137646, BC137647, BC144800 NM_001081347, NM_001252636, NM_001252637, NM_001252638, BC099973, BC137646, BC137647, BC144800 NM_001081347, NM_001252636, NM_001252637, NM_001252638, BC099973, BC137646, BC137647, BC144800 |
69288 |
20 |
nucleotide binding GTPase activity protein binding GTP binding intracellular anatomical structure cytoskeleton plasma membrane cell cortex actin filament organization establishment or maintenance of cell polarity small GTPase mediated signal transduction regulation of cell shape protein kinase binding cortical cytoskeleton organization cytoplasmic vesicle regulation of actin cytoskeleton organization cell projection intracellular membrane-bounded organelle engulfment of apoptotic cell |
04120 |
| TC1900000954.mm.2 |
Pacs1 |
phosphofurin acidic cluster sorting protein 1 |
19 |
-5133684, -5133684 |
NM_153129, BC062886 NM_153129, BC062886 |
107975 |
27 |
Golgi apparatus COPI-coated vesicle positive regulation of protein binding protein localization to Golgi apparatus cellular protein localization ion channel binding ion channel binding perinuclear region of cytoplasm protein localization to plasma membrane protein localization to plasma membrane |
|
| TC0700004188.mm.2 |
Thumpd1 |
THUMP domain containing 1 |
7 |
-119715093 |
NM_145585, BC004776 NM_145585, BC004776 |
233802 |
21 |
RNA binding cellular_component tRNA modification |
|
| TC1400000177.mm.2 |
Vcl |
vinculin |
14 |
20929397 |
NM_009502, BC008520 NM_009502, BC008520 |
22330 |
214 |
stress fiber morphogenesis of an epithelium podosome dystroglycan binding actin binding structural molecule activity protein binding cytoplasm cytoskeleton actin filament plasma membrane cell-cell junction cell-cell junction adherens junction adherens junction fascia adherens focal adhesion focal adhesion cell adhesion intercalated disc actin cytoskeleton membrane Z disc lamellipodium assembly cell junction regulation of cell migration small GTPase binding ubiquitin protein ligase binding protein-containing complex adherens junction assembly protein localization to cell surface sarcolemma sarcolemma costamere costamere apical junction assembly cell-cell contact zone membrane raft alpha-catenin binding axon extension actin filament binding regulation of focal adhesion assembly epithelial cell-cell adhesion regulation of establishment of endothelial barrier regulation of protein localization to adherens junction |
04510 04520 04670 04810 05100 05146 |
| TC1300002609.mm.2 |
Rnf180 |
ring finger protein 180 |
13 |
-105147493, -105130569 |
NM_027934, BC046775, BC075700 NM_027934, BC046775, BC075700 NM_027934, BC046775, BC075700 |
71816 |
19 |
protein polyubiquitination protein binding nucleus endoplasmic reticulum membrane integral component of membrane transferase activity adult behavior intrinsic component of endoplasmic reticulum membrane intrinsic component of endoplasmic reticulum membrane positive regulation of protein ubiquitination ubiquitin conjugating enzyme binding ubiquitin conjugating enzyme binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process norepinephrine metabolic process norepinephrine metabolic process serotonin metabolic process serotonin metabolic process metal ion binding regulation of catalytic activity ubiquitin protein ligase activity ubiquitin protein ligase activity organic cyclic compound metabolic process |
|
| TC0400003271.mm.2 |
Cdkn2c |
cyclin dependent kinase inhibitor 2C |
4 |
-109660875, -109660875 |
NM_007671, BC027026 NM_007671, BC027026 |
12580 |
131 |
regulation of cyclin-dependent protein serine/threonine kinase activity G1/S transition of mitotic cell cycle cyclin-dependent protein serine/threonine kinase inhibitor activity cyclin-dependent protein serine/threonine kinase inhibitor activity nucleus cytoplasm cell cycle cell cycle arrest negative regulation of cell population proliferation negative regulation of cell population proliferation protein kinase binding protein kinase binding negative regulation of cell growth negative regulation of phosphorylation negative regulation of cyclin-dependent protein serine/threonine kinase activity |
04110 |
| TC1500001262.mm.2 |
Hnrnpa1l2-ps2 |
heterogeneous nuclear ribonucleoprotein A1-like 2, pseudogene 2 |
15 |
-22713819 |
NM_001165971 |
545091 |
1 |
|
03040 |
| TC0500002650.mm.2 |
Noa1 |
nitric oxide associated 1 |
5 |
-77294168 |
NM_019836, BC017154 NM_019836, BC017154 |
56412 |
24 |
nucleotide binding GTP binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane apoptotic process regulation of cell death regulation of cell death regulation of cell death membrane extrinsic component of mitochondrial inner membrane mitochondrial translation regulation of cellular respiration regulation of cellular respiration |
|
| TC1300001326.mm.2 |
Emb |
embigin |
13 |
117220572 |
NM_010330, BC014858 NM_010330, BC014858 |
13723 |
43 |
plasma membrane integral component of plasma membrane cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules axon guidance membrane integral component of membrane cell junction axon plasma membrane lactate transport synapse dendrite self-avoidance cell-cell adhesion mediator activity |
|
| TC1600000138.mm.2 |
Snx29 |
sorting nexin 29 |
16 |
11322903, 11405647 |
NM_028964 |
74478 |
15 |
molecular_function biological_process phosphatidylinositol binding |
|
| TC0700001150.mm.2 |
Vps33b |
vacuolar protein sorting 33B |
7 |
80269654 |
NM_178070, BC034170 NM_178070, BC034170 |
233405 |
30 |
protein binding cytoplasm lysosome lysosome endosome late endosome Golgi apparatus intracellular protein transport intracellular protein transport vesicle docking involved in exocytosis endosome organization synaptic vesicle protein transport membrane vesicle-mediated transport vesicle-mediated transport peptidyl-lysine hydroxylation peptidyl-lysine hydroxylation clathrin-coated vesicle collagen fibril organization platelet alpha granule cytoplasmic vesicle early endosome membrane melanosome localization lysosome localization collagen metabolic process collagen metabolic process CORVET complex megakaryocyte development protein-containing complex binding perinuclear region of cytoplasm membrane fusion platelet alpha granule organization platelet alpha granule organization regulation of platelet aggregation |
|
| TC0X00000519.mm.2 |
Ints6l |
integrator complex subunit 6 like |
X |
56454838 |
NM_172779, BC051161, BC066792 NM_172779, BC051161, BC066792 NM_172779, BC051161, BC066792 |
236790 |
15 |
molecular_function integrator complex snRNA 3'-end processing |
|
| TC0X00002158.mm.2 |
Zdhhc9 |
zinc finger, DHHC domain containing 9 |
X |
-48171970 |
NM_172465, BC042618, BC090832 NM_172465, BC042618, BC090832 NM_172465, BC042618, BC090832 |
208884 |
18 |
palmitoyltransferase complex endoplasmic reticulum endoplasmic reticulum Golgi apparatus Golgi apparatus cytosol protein targeting to membrane membrane integral component of membrane palmitoyltransferase activity transferase activity transferase activity, transferring acyl groups peptidyl-L-cysteine S-palmitoylation peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein-cysteine S-palmitoyltransferase activity intrinsic component of Golgi membrane Ras palmitoyltransferase activity |
|
| TC0900001692.mm.2 |
Aasdhppt |
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase |
9 |
-4294792 |
NM_026276, BC030043, BC038013, BC049851 NM_026276, BC030043, BC038013, BC049851 NM_026276, BC030043, BC038013, BC049851 NM_026276, BC030043, BC038013, BC049851 |
67618 |
17 |
magnesium ion binding cytoplasm cytosol cytosol holo-[acyl-carrier-protein] synthase activity holo-[acyl-carrier-protein] synthase activity transferase activity lysine biosynthetic process via aminoadipic acid metal ion binding |
|
| TC0300000880.mm.2 |
Selenbp1 |
selenium binding protein 1 |
3 |
94933082 |
NM_009150, BC011202 NM_009150, BC011202 |
20341 |
31 |
fibrillar center nucleus nucleolus cytoplasm selenium binding protein transport membrane oxidoreductase activity methanethiol oxidase activity brown fat cell differentiation |
|
| TC0200004537.mm.2 |
Atp8b4 |
ATPase, class I, type 8B, member 4 |
2 |
-126320972, -126320972 |
NM_001080944 |
241633 |
12 |
Golgi apparatus trans-Golgi network plasma membrane plasma membrane Golgi organization phospholipid translocation ATPase-coupled intramembrane lipid transporter activity |
|
| TC1200001861.mm.2 |
Pole2 |
polymerase (DNA directed), epsilon 2 (p59 subunit) |
12 |
-69201778 |
NM_011133, BC063772 NM_011133, BC063772 |
18974 |
23 |
DNA binding DNA-directed DNA polymerase activity nucleus nucleoplasm DNA replication DNA-dependent DNA replication epsilon DNA polymerase complex epsilon DNA polymerase complex nuclear body error-prone translesion synthesis intracellular membrane-bounded organelle |
00230 00240 01100 03030 03410 03420 |
| TC1400002867.mm.2 |
Xpo4 |
exportin 4 |
14 |
-57577520, -57639770 |
NM_020506, BC156636 NM_020506, BC156636 |
57258 |
25 |
nuclear export signal receptor activity nucleus nuclear pore nucleoplasm cytoplasm cytosol protein export from nucleus protein transport positive regulation of protein export from nucleus |
|
| TC0900001398.mm.2 |
Nicn1 |
nicolin 1 |
9 |
108290442 |
NM_025449, BC024050 NM_025449, BC024050 |
66257 |
21 |
molecular_function nucleus nucleoplasm nucleoplasm cytosol microtubule biological_process protein polyglutamylation |
|
| TC0600000989.mm.2 |
C87436 |
expressed sequence C87436 |
6 |
86438673, 86438397, 86438645, 86438375 |
NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 NM_001243741, NM_001243742, NM_146170, BC025632, BC026926, BC031913 |
232196 |
18 |
molecular_function nucleus nucleoplasm biological_process |
|
| TC1300002201.mm.2 |
Prxl2c |
peroxiredoxin like 2C |
13 |
-64289797 |
NM_025370, BC156631 NM_025370, BC156631 |
66129 |
13 |
cellular_component antioxidant activity positive regulation of glycolytic process positive regulation of ERK1 and ERK2 cascade |
|
| TC1200000825.mm.2 |
Ylpm1 |
YLP motif containing 1 |
12 |
84996320 |
NM_178363 |
56531 |
25 |
negative regulation of transcription by RNA polymerase II DNA-binding transcription repressor activity, RNA polymerase II-specific nucleus nucleus nucleus nucleoplasm cytosol nuclear speck regulation of telomere maintenance regulation of telomere maintenance |
|
| TC0200002803.mm.2 |
Slc17a9 |
solute carrier family 17, member 9 |
2 |
180725338 |
NM_183161 |
228993 |
36 |
guanine nucleotide transmembrane transporter activity transporter activity ATP transmembrane transporter activity exocytosis ADP transmembrane transporter activity ADP transport ATP transport membrane integral component of membrane secretory granule chromaffin granule membrane chromaffin granule membrane transmembrane transport guanine nucleotide transmembrane transport ATP export |
|
| TC0500003096.mm.2 |
Gatc |
glutamyl-tRNA(Gln) amidotransferase, subunit C |
5 |
-115333241 |
NM_029645, BC021775 NM_029645, BC021775 |
384281 |
14 |
nucleotide binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrion translation regulation of translational fidelity ligase activity glutamyl-tRNA(Gln) amidotransferase complex glutamyl-tRNA(Gln) amidotransferase complex mitochondrial translation mitochondrial translation glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNAGln biosynthesis via transamidation glutaminyl-tRNAGln biosynthesis via transamidation |
|
| TC0400001683.mm.2 |
Hnrnpr |
heterogeneous nuclear ribonucleoprotein R |
4 |
136310941, 136311597 |
NM_001277121, NM_001277122, NM_001277123, NM_028871, BC038051 NM_001277121, NM_001277122, NM_001277123, NM_028871, BC038051 NM_001277121, NM_001277122, NM_001277123, NM_028871, BC038051 NM_001277121, NM_001277122, NM_001277123, NM_028871, BC038051 NM_001277121, NM_001277122, NM_001277123, NM_028871, BC038051 |
74326 |
38 |
RNA binding mRNA binding mRNA 3'-UTR binding nucleus nucleus nucleus nucleoplasm cytoplasm dendrite growth cone negative regulation of catalytic activity axon terminus positive regulation of mRNA catabolic process mRNA destabilization catalytic step 2 spliceosome ribonucleoprotein complex ribonucleoprotein complex |
|
| TC1100003410.mm.2 |
Aatf |
apoptosis antagonizing transcription factor |
11 |
-84422855 |
NM_019816, BC025080 NM_019816, BC025080 |
56321 |
42 |
protein binding nucleus nucleus nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytoplasm Golgi apparatus cytosol regulation of transcription by RNA polymerase II cell adhesion regulation of mitotic cell cycle protein kinase binding negative regulation of superoxide anion generation embryonic cleavage ribosome biogenesis negative regulation of amyloid precursor protein biosynthetic process negative regulation of apoptotic process leucine zipper domain binding positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II tau protein binding negative regulation of reactive oxygen species metabolic process negative regulation of apoptotic signaling pathway |
|
| TC1300000248.mm.2 |
H1f3 |
H1.3 linker histone, cluster member |
13 |
23555031 |
NM_145713, BC117045, BC119173 NM_145713, BC117045, BC119173 NM_145713, BC117045, BC119173 |
14957 |
47 |
negative regulation of transcription by RNA polymerase II chromatin nucleosome euchromatin DNA binding double-stranded DNA binding protein binding nucleus chromosome nucleosome assembly regulation of transcription by RNA polymerase II nucleosome positioning nucleosome positioning chromosome condensation chromatin DNA binding nucleosomal DNA binding negative regulation of chromatin silencing negative regulation of DNA recombination histone H3-K4 trimethylation histone H3-K27 trimethylation |
|
| TC1200000140.mm.2 |
Nol10 |
nucleolar protein 10 |
12 |
17348492 |
NM_001008421, BC086676 NM_001008421, BC086676 |
217431 |
22 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus nucleolus nucleolus small-subunit processome |
|
| TC0200001741.mm.2 |
Bub1b |
BUB1B, mitotic checkpoint serine/threonine kinase |
2 |
118598210 |
NM_009773, BC031577 NM_009773, BC031577 |
12236 |
96 |
nucleotide binding chromosome, centromeric region kinetochore kinetochore kinetochore condensed chromosome kinetochore condensed nuclear chromosome kinetochore condensed nuclear chromosome kinetochore condensed chromosome outer kinetochore condensed chromosome outer kinetochore protein kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus chromosome cytoplasm spindle cytosol protein phosphorylation apoptotic process cell cycle metaphase/anaphase transition of mitotic cell cycle mitotic spindle assembly checkpoint kinase activity phosphorylation transferase activity perinuclear region of cytoplasm cell division meiotic sister chromatid cohesion, centromeric protein localization to chromosome, centromeric region |
04110 |
| TC0200001836.mm.2 |
|
|
|
|
NM_001256055, NM_144545, BC080788 NM_001256055, NM_144545, BC080788 NM_001256055, NM_144545, BC080788 |
|
|
cytosol eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex identical protein binding |
|
| TC0100002963.mm.2 |
Tmem37 |
transmembrane protein 37 |
1 |
-120067376 |
NM_019432, BC024613 NM_019432, BC024613 |
170706 |
20 |
voltage-gated ion channel activity calcium channel activity ion transport calcium ion transport membrane integral component of membrane regulation of ion transmembrane transport calcium ion transmembrane transport |
|
| TC0200002844.mm.2 |
Rpp38 |
ribonuclease P/MRP 38 subunit |
2 |
-3328948 |
NM_001013376, BC051448 NM_001013376, BC051448 |
227522 |
15 |
fibrillar center fibrillar center tRNA 5'-leader removal tRNA 5'-leader removal ribonuclease P activity ribonuclease P activity nucleus nucleolus rRNA processing tRNA processing hydrolase activity multimeric ribonuclease P complex multimeric ribonuclease P complex ribonuclease P RNA binding ribonuclease P RNA binding |
03008 03013 |
| TC0100003021.mm.2 |
Zranb3 |
zinc finger, RAN-binding domain containing 3 |
1 |
-127954178, -127954178, -127954178 |
NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 NM_001285945, NM_027678, BC066035, BC117921, BC117922 |
226409 |
20 |
nucleotide binding nucleic acid binding catalytic activity helicase activity nuclease activity endonuclease activity endodeoxyribonuclease activity endodeoxyribonuclease activity ATP binding nucleus nucleoplasm chromosome DNA repair DNA repair cellular response to DNA damage stimulus metabolic process response to UV hydrolase activity replication fork processing replication fork processing DNA rewinding annealing helicase activity nuclear replication fork nuclear replication fork negative regulation of DNA recombination metal ion binding replication fork protection replication fork protection K63-linked polyubiquitin modification-dependent protein binding |
|
| TC0400002709.mm.2 |
Tmem245 |
transmembrane protein 245 |
4 |
-56876013, -56876012 |
NM_175518 |
242474 |
16 |
membrane integral component of membrane |
|
| TC0900002302.mm.2 |
Ddx10 |
DEAD box helicase 10 |
9 |
-53098453 |
NM_029936, BC080729 NM_029936, BC080729 |
77591 |
21 |
nucleotide binding nucleic acid binding RNA binding helicase activity ATP binding nucleus rRNA processing hydrolase activity anterior head development |
|
| TC1500001585.mm.2 |
Mtss1 |
MTSS I-BAR domain containing 1 |
15 |
-58941233 |
NM_001146180, NM_144800, BC024131 NM_001146180, NM_144800, BC024131 NM_001146180, NM_144800, BC024131 |
211401 |
51 |
in utero embryonic development actin binding actin monomer binding signaling receptor binding protein binding cytoplasm cytoskeleton adherens junction plasma membrane organization actin filament organization nervous system development muscle organ development magnesium ion homeostasis actin cytoskeleton actin cytoskeleton organization actin filament polymerization bone mineralization positive regulation of actin filament bundle assembly adherens junction maintenance identical protein binding identical protein binding negative regulation of epithelial cell proliferation actin filament binding renal tubule morphogenesis cellular response to fluid shear stress glomerulus morphogenesis nephron tubule epithelial cell differentiation metanephric tubule development epithelial cell proliferation involved in renal tubule morphogenesis |
|
| TC1100001331.mm.2 |
Trim37 |
tripartite motif-containing 37 |
11 |
87127074, 87127074 |
NM_197987, BC058678, BC059070 NM_197987, BC058678, BC059070 NM_197987, BC058678, BC059070 |
68729 |
31 |
negative regulation of transcription by RNA polymerase II chromatin binding transcription coactivator activity ubiquitin-protein transferase activity tumor necrosis factor receptor binding tumor necrosis factor receptor binding intracellular anatomical structure cytoplasm peroxisome peroxisome cytosol zinc ion binding aggresome aggresome protein ubiquitination transferase activity ubiquitin protein ligase binding ubiquitin protein ligase binding negative regulation of NF-kappaB transcription factor activity negative regulation of NF-kappaB transcription factor activity ESC/E(Z) complex histone H2A monoubiquitination histone H2A monoubiquitination histone H2A-K119 monoubiquitination histone H2A-K119 monoubiquitination histone H2A-K119 monoubiquitination protein homodimerization activity negative regulation of centriole replication negative regulation of centriole replication metal ion binding positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity protein autoubiquitination protein autoubiquitination ubiquitin protein ligase activity ubiquitin protein ligase activity aggresome assembly |
04120 |
| TC0400002613.mm.2 |
Alg2 |
asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) |
4 |
-47469832 |
NM_019998, BC051951, BC052411 NM_019998, BC051951, BC052411 NM_019998, BC051951, BC052411 |
56737 |
22 |
alpha-1,3-mannosyltransferase activity alpha-1,3-mannosyltransferase activity GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity nucleus cytoplasm cytosol protein glycosylation dolichol-linked oligosaccharide biosynthetic process oligosaccharide-lipid intermediate biosynthetic process actin cytoskeleton membrane integral component of membrane transferase activity transferase activity, transferring glycosyl groups protein glycosylation in endoplasmic reticulum protein glycosylation in endoplasmic reticulum protein heterodimerization activity protein N-terminus binding calcium-dependent protein binding perinuclear region of cytoplasm response to calcium ion GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity |
00510 01100 |
| TC0900001009.mm.2 |
Myo5a |
myosin VA |
9 |
75071205 |
NM_010864 |
17918 |
275 |
microfilament motor activity microfilament motor activity microfilament motor activity microfilament motor activity SNARE binding nucleotide binding ruffle photoreceptor outer segment motor activity motor activity actin binding calcium ion binding protein binding calmodulin binding ATP binding cytoplasm cytoplasm cytoplasm lysosome early endosome late endosome peroxisome endoplasmic reticulum smooth endoplasmic reticulum smooth endoplasmic reticulum Golgi apparatus cytosol cytosol intermediate filament actin filament melanin metabolic process exocytosis post-Golgi vesicle-mediated transport actin filament organization chemical synaptic transmission visual perception synaptic vesicle protein transport actin cytoskeleton membrane vesicle-mediated transport myosin complex unconventional myosin complex syntaxin-1 binding regulation of exocytosis protein kinase binding actin filament-based movement actin filament-based movement vesicle transport along actin filament vesicle transport along actin filament vesicle transport along actin filament insulin secretion secretory granule secretory granule melanocyte differentiation axon dendrite actin-dependent ATPase activity small GTPase binding small GTPase binding regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity vesicle vesicle locomotion involved in locomotory behavior secretory granule localization secretory granule localization melanosome localization melanosome transport melanosome transport filopodium tip insulin-responsive compartment cellular response to insulin stimulus melanin biosynthetic process melanosome melanosome odontogenesis myelination anagen actomyosin actomyosin, myosin complex part long-chain fatty acid biosynthetic process identical protein binding neuron projection ATP-dependent protein binding neuronal cell body neuronal cell body pigmentation pigmentation protein-containing complex binding developmental pigmentation calcium-dependent protein binding hair follicle maturation synapse organization neuromuscular process controlling balance actin filament binding endoplasmic reticulum localization recycling endosome protein-containing complex assembly protein localization to plasma membrane disordered domain specific binding Schaffer collateral - CA1 synapse postsynapse postsynapse postsynaptic actin cytoskeleton glutamatergic synapse glutamatergic synapse glutamatergic synapse establishment of endoplasmic reticulum localization to postsynapse establishment of endoplasmic reticulum localization to postsynapse regulation of postsynaptic cytosolic calcium ion concentration regulation of postsynaptic cytosolic calcium ion concentration axo-dendritic protein transport positive regulation of cellular response to insulin stimulus positive regulation of protein localization to plasma membrane positive regulation of vascular associated smooth muscle cell migration ribonucleoprotein complex |
|
| TC0200002720.mm.2 |
|
|
|
|
NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 NM_001177404, NM_001177405, NM_001177406, NM_001177407, XM_003688775 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II |
|
| TC0200002738.mm.2 |
|
|
|
|
NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407 NM_001177405, NM_001177406, NM_001177404, NM_001177407 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II |
|
| TC0200005341.mm.2 |
|
|
|
|
NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 NM_001177404, NM_001177407, NM_001177405, NM_001177406, XM_001480068 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II |
|
| TC0200000647.mm.2 |
Mrrf |
mitochondrial ribosome recycling factor |
2 |
36136397 |
NM_026422, BC019787 NM_026422, BC019787 |
67871 |
19 |
mitochondrion mitochondrion translation ribosome disassembly ribosomal large subunit binding |
|
| TC0100001699.mm.2 |
Sccpdh |
saccharopine dehydrogenase (putative) |
1 |
179668230 |
NM_178653, BC025803 NM_178653, BC025803 |
109232 |
18 |
molecular_function mitochondrion mitochondrion lipid droplet lipid droplet plasma membrane glycolipid biosynthetic process oxidoreductase activity midbody |
|
| TC0600000928.mm.2 |
Bola3 |
bolA-like 3 (E. coli) |
6 |
83349475, 83349146, 83349215 |
NM_175277, BC116947, BC116949 NM_175277, BC116947, BC116949 NM_175277, BC116947, BC116949 |
78653 |
17 |
molecular_function mitochondrion cytosol biological_process nuclear body |
|
| TC1700000603.mm.2 |
Wdr46 |
WD repeat domain 46 |
17 |
33940722 |
NM_020603, BC046977 NM_020603, BC046977 |
57315 |
20 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus nucleolus small-subunit processome |
|
| TC0100000464.mm.2 |
Fam117b |
family with sequence similarity 117, member B |
1 |
59913005 |
NM_001037725 |
72750 |
15 |
molecular_function biological_process |
|
| TC0200005342.mm.2 |
|
|
|
|
NM_001199308, NM_001033123 NM_001199308, NM_001033123 |
|
|
molecular_function cellular_component biological_process |
|
| TC1500000826.mm.2 |
Gtse1 |
G two S phase expressed protein 1 |
15 |
85859706, 85859945 |
NM_001168672, NM_013882, BC027213 NM_001168672, NM_013882, BC027213 NM_001168672, NM_013882, BC027213 |
29870 |
28 |
cytoplasm cytoskeleton microtubule cytoplasmic microtubule cytoplasmic microtubule microtubule binding microtubule cytoskeleton |
04115 |
| TC1300001349.mm.2 |
Tmem267 |
transmembrane protein 267 |
13 |
119488472, 119488085 |
NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784 NM_001039244, NM_001177666, BC021422, BC103784 |
633640 |
12 |
molecular_function cellular_component biological_process membrane integral component of membrane |
|
| TC0200005365.mm.2 |
|
|
|
|
|
|
|
|
|
| TC0100001943.mm.2 |
Mybl1 |
myeloblastosis oncogene-like 1 |
1 |
-9667410 |
NM_008651, BC103533 NM_008651, BC103533 |
17864 |
43 |
mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding nucleus nucleus nucleoplasm regulation of transcription, DNA-templated male meiosis I spermatogenesis negative regulation of transposition cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II piRNA biosynthetic process |
|
| TC1300000543.mm.2 |
Rnf144b |
ring finger protein 144B |
13 |
47194002, 47122719 |
NM_001170643, NM_146042, BC025007 NM_001170643, NM_146042, BC025007 NM_001170643, NM_146042, BC025007 |
218215 |
20 |
ubiquitin ligase complex protein polyubiquitination ubiquitin-protein transferase activity cytoplasm cytoplasm mitochondrion ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process apoptotic process membrane integral component of membrane protein ubiquitination transferase activity ubiquitin conjugating enzyme binding mitochondrial membrane mitochondrial membrane positive regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of apoptotic process metal ion binding ubiquitin protein ligase activity |
|
| TC1400002756.mm.2 |
Ggact |
gamma-glutamylamine cyclotransferase |
14 |
-122890859 |
NM_145466, BC006662, BC080839 NM_145466, BC006662, BC080839 NM_145466, BC006662, BC080839 |
223267 |
12 |
cytosol lyase activity cellular modified amino acid catabolic process gamma-glutamylaminecyclotransferase activity |
|
| TC0300002973.mm.2 |
Gstcd |
glutathione S-transferase, C-terminal domain containing |
3 |
-132981749, -132981749 |
NM_026231, BC047136, BC061240 NM_026231, BC047136, BC061240 NM_026231, BC047136, BC061240 |
67553 |
20 |
protein binding cytoplasm cytoplasm biological_process |
|
| TC1200001314.mm.2 |
Rapgef5 |
Rap guanine nucleotide exchange factor (GEF) 5 |
12 |
117516525, 117533927 |
NM_175930, BC046627 NM_175930, BC046627 |
217944 |
25 |
guanyl-nucleotide exchange factor activity intracellular anatomical structure nucleus nucleoplasm small GTPase mediated signal transduction nuclear body GTP-dependent protein binding intracellular signal transduction |
|
| TC1100000007.mm.2 |
|
|
|
|
NM_001253690, NM_001253691, NM_019574, NR_045108, NR_045109, NR_045708, BC043035 NM_001253690, NM_001253691, NM_019574, NR_045108, NR_045109, NR_045708, BC043035 NM_001253690, NM_001253691, NM_019574, NR_045108, NR_045109, NR_045708, BC043035 NM_001253690, NM_001253691, NM_019574, NR_045108, NR_045109, NR_045708, BC043035 NM_001253690, NM_001253691, NM_019574, NR_045108, NR_045109, NR_045708, BC043035 NM_001253690, NM_001253691, NM_019574, NR_045108, NR_045109, NR_045708, BC043035 NM_001253690, NM_001253691, NM_019574, NR_045108, NR_045109, NR_045708, BC043035 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific chromatin binding protein binding nucleus nucleus nucleoplasm nucleoplasm regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II spermatogenesis male gonad development regulation of gene expression negative regulation of endothelial cell migration T cell differentiation ubiquitin protein ligase binding negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II |
|
| TC0300001289.mm.2 |
Zgrf1 |
zinc finger, GRF-type containing 1 |
3 |
127553488 |
NM_197997 |
71643 |
15 |
RNA binding cytoplasm zinc ion binding membrane integral component of membrane 5'-flap endonuclease activity metal ion binding replication fork reversal |
|
| TC0700004326.mm.2 |
Zfp764 |
zinc finger protein 764 |
7 |
-127403667 |
NM_001167832, NM_146203, BC026397 NM_001167832, NM_146203, BC026397 NM_001167832, NM_146203, BC026397 |
233893 |
16 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| TC0600003000.mm.2 |
Bms1 |
BMS1, ribosome biogenesis factor |
6 |
-118383380 |
NM_194339, BC057054 NM_194339, BC057054 |
213895 |
17 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleoplasm chromosome nucleolus 90S preribosome U3 snoRNA binding |
03008 |
| TC1100003551.mm.2 |
Utp18 |
UTP18 small subunit processome component |
11 |
-93859242 |
NM_001013375, BC119621, BC119622 NM_001013375, BC119621, BC119622 NM_001013375, BC119621, BC119622 |
217109 |
21 |
nucleus nucleoplasm nucleolus rRNA processing nuclear membrane small-subunit processome Pwp2p-containing subcomplex of 90S preribosome |
03008 |
| TC0300001797.mm.2 |
Zmat3 |
zinc finger matrin type 3 |
3 |
-32334793 |
NM_009517, BC138740, BC138742 NM_009517, BC138740, BC138742 NM_009517, BC138740, BC138742 |
22401 |
33 |
nucleic acid binding RNA binding nucleus nucleoplasm nucleolus plasma membrane apoptotic process cellular response to DNA damage stimulus zinc ion binding protein transport negative regulation of cell growth regulation of growth positive regulation of apoptotic process metal ion binding |
04115 |
| TC1500000165.mm.2 |
Retreg1 |
reticulophagy regulator 1 |
15 |
25933551, 25940825, 25843297, 25940701, 25942678 |
NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459, BC019494, BC054415 NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459, BC019494, BC054415 NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459, BC019494, BC054415 NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459, BC019494, BC054415 NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459, BC019494, BC054415 NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459, BC019494, BC054415 NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459, BC019494, BC054415 NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459, BC019494, BC054415 |
66270 |
28 |
molecular_function nucleolus endoplasmic reticulum Golgi apparatus cis-Golgi network autophagy membrane integral component of membrane nuclear body sensory perception of pain integral component of endoplasmic reticulum membrane integral component of endoplasmic reticulum membrane negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process reticulophagy reticulophagy reticulophagy |
|
| TC0300000711.mm.2 |
Nes |
nestin |
3 |
87971092 |
NM_016701, BC060693, BC062893 NM_016701, BC060693, BC062893 NM_016701, BC060693, BC062893 |
18008 |
988 |
protein binding cytoplasm intermediate filament intermediate filament intermediate filament multicellular organism development nervous system development intermediate filament binding positive regulation of intermediate filament depolymerization CCR5 chemokine receptor binding CCR5 chemokine receptor binding negative regulation of neuron apoptotic process cell projection morphogenesis |
|
| TC0200005476.mm.2 |
Nup35 |
nucleoporin 35 |
2 |
80639263, 80638811 |
NM_001190179, NM_027091, BC048814 NM_001190179, NM_027091, BC048814 NM_001190179, NM_027091, BC048814 |
69482 |
22 |
nucleic acid binding single-stranded DNA binding phospholipid binding nucleus nuclear pore nuclear lamina nucleoplasm plasma membrane regulation of transcription, DNA-templated NLS-bearing protein import into nucleus nuclear pore organization protein transport membrane structural constituent of nuclear pore nuclear membrane identical protein binding nuclear pore central transport channel nuclear pore nuclear basket mRNA transport cellular response to leukemia inhibitory factor |
03013 |
| TC0500000785.mm.2 |
Stap1 |
signal transducing adaptor family member 1 |
5 |
86071745 |
NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830 NM_019992, BC145550, BC145828, BC145830 |
56792 |
26 |
phosphotyrosine residue binding transmembrane receptor protein tyrosine kinase adaptor activity macrophage colony-stimulating factor receptor binding protein binding nucleus nucleoplasm cytoplasm mitochondrion transmembrane receptor protein tyrosine kinase signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway response to bacterium positive regulation of gene expression negative regulation of macrophage chemotaxis protein kinase binding protein kinase binding myeloid cell differentiation protein-macromolecule adaptor activity receptor tyrosine kinase binding protein-containing complex signaling adaptor activity signaling adaptor activity negative regulation of phosphorylation intracellular membrane-bounded organelle positive regulation of B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of phagocytosis, engulfment cellular response to lipopolysaccharide negative regulation of ruffle assembly negative regulation of macrophage colony-stimulating factor signaling pathway positive regulation of microglial cell activation positive regulation of non-membrane spanning protein tyrosine kinase activity negative regulation of microglial cell migration positive regulation of microglial cell mediated cytotoxicity positive regulation of actin cytoskeleton reorganization |
|
| TC0100000937.mm.2 |
Farp2 |
FERM, RhoGEF and pleckstrin domain protein 2 |
1 |
93512103 |
NM_145519, BC009153 NM_145519, BC009153 |
227377 |
28 |
guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity cytoplasm cytosol cytoskeleton cell adhesion cytoskeletal protein binding neuron remodeling Rac protein signal transduction hair cycle process osteoclast differentiation actin cytoskeleton reorganization regulation of integrin activation regulation of Rho protein signal transduction semaphorin-plexin signaling pathway podosome assembly |
04520 |
| TC1600000530.mm.2 |
Polq |
polymerase (DNA directed), theta |
16 |
37011785 |
NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900 NM_001159369, NM_029977, BC138360, BC157900 |
77782 |
34 |
nucleotide binding nucleic acid binding DNA binding chromatin binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity ATP binding nucleus nucleoplasm chromosome cytoplasm Golgi apparatus cytosol DNA replication DNA-dependent DNA replication DNA repair DNA repair base-excision repair double-strand break repair cellular response to DNA damage stimulus 5'-3' exonuclease activity somatic hypermutation of immunoglobulin genes transferase activity nucleotidyltransferase activity single-stranded DNA helicase activity identical protein binding protein homooligomerization 5'-deoxyribose-5-phosphate lyase activity double-strand break repair via alternative nonhomologous end joining double-strand break repair via alternative nonhomologous end joining negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination |
|
| TC1200002518.mm.2 |
Asap2 |
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 |
12 |
21111755 |
NM_001004364, NM_001098168, NM_001135192, BC080847, BC096022 NM_001004364, NM_001098168, NM_001135192, BC080847, BC096022 NM_001004364, NM_001098168, NM_001135192, BC080847, BC096022 NM_001004364, NM_001098168, NM_001135192, BC080847, BC096022 NM_001004364, NM_001098168, NM_001135192, BC080847, BC096022 |
211914 |
29 |
GTPase activator activity cellular_component cytoplasm Golgi apparatus plasma membrane membrane metal ion binding |
04144 04666 |
| TC0100002631.mm.2 |
Farsb |
phenylalanyl-tRNA synthetase, beta subunit |
1 |
-78424744, -78417957 |
NM_001278075, NM_011811, NR_102757, NR_102758, BC002313, BC016428 NM_001278075, NM_011811, NR_102757, NR_102758, BC002313, BC016428 NM_001278075, NM_011811, NR_102757, NR_102758, BC002313, BC016428 NM_001278075, NM_011811, NR_102757, NR_102758, BC002313, BC016428 NM_001278075, NM_011811, NR_102757, NR_102758, BC002313, BC016428 NM_001278075, NM_011811, NR_102757, NR_102758, BC002313, BC016428 |
23874 |
32 |
nucleotide binding magnesium ion binding RNA binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding cytoplasm translation phenylalanyl-tRNA aminoacylation phenylalanyl-tRNA aminoacylation phenylalanine-tRNA ligase complex phenylalanine-tRNA ligase complex ligase activity protein heterotetramerization |
00970 |
| TC0500002458.mm.2 |
Arap2 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
5 |
-62602445 |
NM_178407 |
212285 |
18 |
GTPase activator activity phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm signal transduction positive regulation of GTPase activity metal ion binding |
04144 |
| TC1300000273.mm.2 |
Cmah |
cytidine monophospho-N-acetylneuraminic acid hydroxylase |
13 |
24327403, 24415121 |
NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 NM_001111110, NM_001284519, NM_001284520, NM_007717, BC055079 |
12763 |
51 |
cytoplasm endoplasmic reticulum oxidoreductase activity CMP-N-acetylneuraminate monooxygenase activity CMP-N-acetylneuraminate monooxygenase activity CMP-N-acetylneuraminate metabolic process metal ion binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding |
00520 |
| TC1100000383.mm.2 |
Pank3 |
pantothenate kinase 3 |
11 |
35769494 |
NM_145962, BC027089 NM_145962, BC027089 |
211347 |
27 |
nucleotide binding pantothenate kinase activity pantothenate kinase activity pantothenate kinase activity ATP binding nucleus cytoplasm cytosol cytosol coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process kinase activity phosphorylation transferase activity vitamin binding protein homodimerization activity acetyl-CoA binding |
00770 01100 |
| TC1400002341.mm.2 |
Polr3d |
polymerase (RNA) III (DNA directed) polypeptide D |
14 |
-70438747, -70438747 |
NM_001164082, NM_025945, BC016102 NM_001164082, NM_025945, BC016102 NM_001164082, NM_025945, BC016102 |
67065 |
19 |
immune system process DNA binding chromatin binding chromatin binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex cytosol transcription by RNA polymerase III positive regulation of interferon-beta production innate immune response positive regulation of innate immune response defense response to virus |
00230 00240 01100 03020 04623 |
| TC1300000626.mm.2 |
Simc1 |
SUMO-interacting motifs containing 1 |
13 |
54503804 |
NM_176987, BC167252 NM_176987, BC167252 |
319719 |
12 |
cytoplasm biological_process sarcomere peptidase inhibitor activity SUMO polymer binding SUMO polymer binding |
|
| TC0200002044.mm.2 |
Crls1 |
cardiolipin synthase 1 |
2 |
132847733, 132846665 |
NM_001024385, NM_025646, BC048702 NM_001024385, NM_025646, BC048702 NM_001024385, NM_025646, BC048702 |
66586 |
24 |
mitochondrion mitochondrion mitochondrial inner membrane lipid metabolic process phospholipid biosynthetic process cardiolipin synthase activity cardiolipin synthase activity membrane integral component of membrane transferase activity phosphotransferase activity, for other substituted phosphate groups mitochondrial membrane cardiolipin biosynthetic process glycerophospholipid biosynthetic process response to thyroxine response to phosphatidylethanolamine |
00564 01100 |
| TC1100000544.mm.2 |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
11 |
50377677, 50378290, 50377796, 50378235, 50376989 |
NM_021510, BC042187, BC056224 NM_021510, BC042187, BC056224 NM_021510, BC042187, BC056224 |
59013 |
52 |
nucleic acid binding RNA binding RNA binding protein binding nucleus nucleoplasm nucleoplasm spliceosomal complex cytosol mRNA processing RNA splicing identical protein binding regulation of RNA splicing regulation of RNA splicing catalytic step 2 spliceosome cellular response to interleukin-7 ribonucleoprotein complex |
|
| TC0200000459.mm.2 |
Surf2 |
surfeit gene 2 |
2 |
26916407 |
NM_013678, BC096401 NM_013678, BC096401 |
20931 |
21 |
molecular_function nucleoplasm nucleolus plasma membrane biological_process nuclear speck |
|
| TC0200003182.mm.2 |
Qsox2 |
quiescin Q6 sulfhydryl oxidase 2 |
2 |
-26209123 |
NM_153559, BC030934 NM_153559, BC030934 |
227638 |
17 |
protein disulfide isomerase activity extracellular space nucleoplasm Golgi apparatus protein folding membrane integral component of membrane oxidoreductase activity flavin-linked sulfhydryl oxidase activity thiol oxidase activity integral component of Golgi membrane cell redox homeostasis |
|
| TC0200000055.mm.2 |
Nudt5 |
nudix (nucleoside diphosphate linked moiety X)-type motif 5 |
2 |
5845033 |
NM_016918, BC004571, BC049595 NM_016918, BC004571, BC049595 NM_016918, BC004571, BC049595 |
53893 |
28 |
magnesium ion binding RNA binding nucleus nucleus nucleobase-containing compound metabolic process chromatin remodeling nucleoside phosphate metabolic process ribonucleoside diphosphate catabolic process transferase activity nucleotidyltransferase activity hydrolase activity nucleoside-diphosphatase activity ADP-sugar diphosphatase activity D-ribose catabolic process ribose phosphate metabolic process snoRNA binding identical protein binding protein homodimerization activity 8-oxo-dGDP phosphatase activity metal ion binding ADP-ribose diphosphatase activity ADP-ribose diphosphatase activity ATP generation from poly-ADP-D-ribose |
00230 |
| TC0900000285.mm.2 |
Arhgap32 |
Rho GTPase activating protein 32 |
9 |
32115987, 32224274, 32032302, 32016624 |
NM_001195632, NM_177379, BC132390, BC138042 NM_001195632, NM_177379, BC132390, BC138042 NM_001195632, NM_177379, BC132390, BC138042 NM_001195632, NM_177379, BC132390, BC138042 |
330914 |
41 |
fibrillar center fibrillar center GTPase activator activity GTPase activator activity protein binding nucleoplasm nucleoplasm cytoplasm endosome endoplasmic reticulum Golgi apparatus Golgi apparatus cell cortex cell cortex signal transduction small GTPase mediated signal transduction Rho protein signal transduction postsynaptic density actin cytoskeleton actin cytoskeleton membrane cell junction phosphatidylinositol binding cell projection synapse |
|
| TC0600003148.mm.2 |
Cd9 |
CD9 antigen |
6 |
-125460265 |
NM_007657, BC070474, CD9 NM_007657, BC070474, CD9 NM_007657, BC070474, CD9 |
12527 |
130 |
integrin binding integrin binding protein binding extracellular region plasma membrane plasma membrane integral component of plasma membrane cell adhesion single fertilization fusion of sperm to egg plasma membrane involved in single fertilization fusion of sperm to egg plasma membrane involved in single fertilization negative regulation of cell population proliferation glial cell migration external side of plasma membrane cell surface myoblast fusion involved in skeletal muscle regeneration membrane integral component of membrane apical plasma membrane paranodal junction assembly receptor internalization protein-containing complex sperm-egg recognition negative regulation of cellular component movement extracellular exosome extracellular exosome cellular response to low-density lipoprotein particle stimulus negative regulation of platelet aggregation regulation of macrophage migration |
04640 |
| TC0200005335.mm.2 |
|
|
|
|
NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480, XR_140545 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480, XR_140545 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480, XR_140545 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480, XR_140545 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480, XR_140545 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480, XR_140545 NM_001099349, NM_001100415, NM_001100416, NM_001101804, NM_001177543, NM_001256480, XR_140545 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific molecular_function cellular_component nucleus regulation of transcription by RNA polymerase II biological_process |
|
| TC1100003345.mm.2 |
Myo1d |
myosin ID |
11 |
-80482126 |
NM_177390, BC150765 NM_177390, BC150765 |
338367 |
34 |
microfilament motor activity microfilament motor activity nucleotide binding motor activity actin binding protein binding calmodulin binding ATP binding cytoplasm endosome smooth endoplasmic reticulum plasma membrane microvillus brush border brush border actin filament organization negative regulation of phosphatase activity protein transport actin cytoskeleton membrane basolateral plasma membrane myosin complex protein domain specific binding vesicle transport along actin filament axon axolemma actin-dependent ATPase activity actin-dependent ATPase activity cytoplasmic vesicle vesicle cell projection neuron projection neuronal cell body neuronal cell body myelin sheath myelin sheath myelin sheath plasma membrane raft calcium-dependent protein binding actin filament binding actin filament binding cellular localization apical dendrite |
|
| TC1100004000.mm.2 |
Abca9 |
ATP-binding cassette, sub-family A (ABC1), member 9 |
11 |
-110100821 |
NM_147220 |
217262 |
15 |
nucleotide binding lipid transporter activity ATP binding mitochondrion lipid transport membrane integral component of membrane ATPase activity ATPase-coupled transmembrane transporter activity intracellular membrane-bounded organelle |
02010 |
| TC0900000050.mm.2 |
Mmp8 |
matrix metallopeptidase 8 |
9 |
7558428 |
NM_008611, BC042742 NM_008611, BC042742 |
17394 |
93 |
endopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding extracellular region extracellular space extracellular space proteolysis peptidase activity metallopeptidase activity zinc ion binding positive regulation of gene expression negative regulation of gene expression hydrolase activity extracellular matrix organization collagen catabolic process extracellular matrix negative regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of DNA binding positive regulation of MAPK cascade positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process positive regulation of JNK cascade metal ion binding positive regulation of neuroinflammatory response positive regulation of neuroinflammatory response positive regulation of NIK/NF-kappaB signaling positive regulation of reactive oxygen species biosynthetic process positive regulation of microglial cell activation |
|
| TC1800001255.mm.2 |
Lars |
leucyl-tRNA synthetase |
18 |
-42202297 |
NM_134137, BC052715 NM_134137, BC052715 |
107045 |
30 |
nucleotide binding aminoacyl-tRNA editing activity aminoacyl-tRNA ligase activity glutamine-tRNA ligase activity leucine-tRNA ligase activity leucine-tRNA ligase activity GTPase activator activity ATP binding cytoplasm lysosome endoplasmic reticulum cytosol translation tRNA aminoacylation for protein translation glutaminyl-tRNA aminoacylation leucyl-tRNA aminoacylation leucyl-tRNA aminoacylation regulation of cell size endomembrane system nuclear body ligase activity aminoacyl-tRNA synthetase multienzyme complex aminoacyl-tRNA synthetase multienzyme complex positive regulation of TOR signaling cellular response to amino acid starvation positive regulation of GTPase activity cellular response to amino acid stimulus cellular response to leucine positive regulation of TORC1 signaling cellular response to leucine starvation |
00290 00970 |
| TC0900000639.mm.2 |
Poglut3 |
protein O-glucosyltransferase 3 |
9 |
53384022 |
NM_212445 |
68304 |
16 |
endoplasmic reticulum endomembrane system transferase activity transferase activity, transferring glycosyl groups protein O-linked glycosylation via serine UDP-glucosyltransferase activity UDP-xylosyltransferase activity glucosyltransferase activity |
|
| TC1900000758.mm.2 |
Smc3 |
structural maintenance of chromosomes 3 |
19 |
53600395 |
NM_007790, BC057345, BC062935 NM_007790, BC057345, BC062935 NM_007790, BC057345, BC062935 |
13006 |
75 |
nucleotide binding chromosome, centromeric region chromatin lateral element chromatin binding protein binding ATP binding basement membrane nucleus nucleoplasm nucleoplasm chromosome regulation of DNA replication DNA repair cellular response to DNA damage stimulus cell cycle sister chromatid cohesion cohesin complex cohesin complex nuclear matrix stem cell population maintenance meiotic cohesin complex meiotic cohesin complex nuclear meiotic cohesin complex mediator complex binding protein heterodimerization activity beta-tubulin binding chromosome organization cell division meiotic cell cycle meiotic cell cycle dynein complex binding mitotic spindle assembly mitotic spindle pole |
04110 04114 |
| TC0200000013.mm.2 |
Fam107b |
family with sequence similarity 107, member B |
2 |
3713457 |
NM_025626, BC021353 NM_025626, BC021353 |
66540 |
18 |
molecular_function cellular_component sensory perception of sound |
|
| TC0300002580.mm.2 |
Wdr3 |
WD repeat domain 3 |
3 |
-100138179 |
NM_175552, BC063100 NM_175552, BC063100 |
269470 |
20 |
nucleus nucleoplasm nucleolus maturation of SSU-rRNA snoRNA binding nuclear membrane small-subunit processome Pwp2p-containing subcomplex of 90S preribosome |
03008 |
| TC1200001625.mm.2 |
Hdac9 |
histone deacetylase 9 |
12 |
-34047581, -34371496 |
NM_001271386, NM_024124, BC098187, XM_003688889 NM_001271386, NM_024124, BC098187, XM_003688889 NM_001271386, NM_024124, BC098187, XM_003688889 NM_001271386, NM_024124, BC098187, XM_003688889 |
79221 |
83 |
histone deacetylase complex negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of cytokine production transcription corepressor activity transcription corepressor activity histone deacetylase activity protein kinase C binding protein binding nucleus nucleus transcription regulator complex cytoplasm cytoplasm DNA repair chromatin organization inflammatory response nervous system development heart development transcription factor binding transcription factor binding determination of adult lifespan histone deacetylation hydrolase activity B cell differentiation NAD-dependent histone deacetylase activity (H3-K14 specific) cellular response to insulin stimulus protein deacetylase activity histone deacetylase activity (H4-K16 specific) peptidyl-lysine deacetylation histone methyltransferase complex B cell activation cholesterol homeostasis histone deacetylase binding negative regulation of striated muscle tissue development negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated negative regulation of transcription, DNA-templated regulation of skeletal muscle fiber development negative regulation of lipoprotein lipase activity regulation of striated muscle cell differentiation repressing transcription factor binding repressing transcription factor binding repressing transcription factor binding histone H3 deacetylation histone H4 deacetylation positive regulation of cell migration involved in sprouting angiogenesis histone H4-K16 deacetylation |
|
| TC1100004267.mm.2 |
Trim16 |
tripartite motif-containing 16 |
11 |
62820252 |
NM_053169, BC052821 NM_053169, BC052821 |
94092 |
20 |
DNA binding cytoplasm cytoplasm cytosol plasma membrane zinc ion binding PML body transferase activity interleukin-1 binding NACHT domain binding positive regulation of interleukin-1 beta production histone H3 acetylation histone H4 acetylation positive regulation of keratinocyte differentiation positive regulation of transcription, DNA-templated metal ion binding positive regulation of retinoic acid receptor signaling pathway response to growth hormone |
|
| TC0300000916.mm.2 |
Anp32e |
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
3 |
95929256 |
NM_001253757, NM_001253758, NM_023210, BC005690, BC080684 NM_001253757, NM_001253758, NM_023210, BC005690, BC080684 NM_001253757, NM_001253758, NM_023210, BC005690, BC080684 NM_001253757, NM_001253758, NM_023210, BC005690, BC080684 NM_001253757, NM_001253758, NM_023210, BC005690, BC080684 |
66471 |
33 |
nucleus nucleus cytoplasm chromatin organization phosphatase inhibitor activity phosphatase inhibitor activity cytoplasmic vesicle histone binding regulation of apoptotic process histone exchange |
|
| TC0200001947.mm.2 |
Polr1b |
polymerase (RNA) I polypeptide B |
2 |
129100995 |
NM_009086, BC060656 NM_009086, BC060656 |
20017 |
35 |
DNA binding DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity protein binding nucleus nucleoplasm chromosome nucleolus nucleolus RNA polymerase I complex RNA polymerase I complex RNA polymerase I complex cytosol transcription, DNA-templated embryo implantation rRNA transcription rRNA transcription embryo development transferase activity nucleotidyltransferase activity nucleologenesis ribonucleoside binding metal ion binding |
00230 00240 01100 03020 |
| TC1200001248.mm.2 |
Zfyve21 |
zinc finger, FYVE domain containing 21 |
12 |
111814169, 111814229 |
NM_026752, BC019521, BC132248, BC132250 NM_026752, BC019521, BC132248, BC132250 NM_026752, BC019521, BC132248, BC132250 NM_026752, BC019521, BC132248, BC132250 |
68520 |
21 |
molecular_function cellular_component endosome biological_process cell junction cytoplasmic vesicle metal ion binding |
|
| TC1600000291.mm.2 |
Polr2h |
polymerase (RNA) II (DNA directed) polypeptide H |
16 |
20718176, 20717825 |
NM_145632, BC002306, BC092087, BC125612, BC125638 NM_145632, BC002306, BC092087, BC125612, BC125638 NM_145632, BC002306, BC092087, BC125612, BC125638 NM_145632, BC002306, BC092087, BC125612, BC125638 NM_145632, BC002306, BC092087, BC125612, BC125638 |
245841 |
24 |
DNA binding single-stranded DNA binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase II, core complex RNA polymerase II, core complex RNA polymerase III complex RNA polymerase I complex transcription, DNA-templated transcription by RNA polymerase II transcription by RNA polymerase II protein-DNA complex |
00230 00240 01100 03020 05016 |
| TC1800000019.mm.2 |
Svil |
supervillin |
18 |
5046588, 5046588 |
NM_153153 |
225115 |
32 |
actin binding protein binding phosphatidylinositol-4,5-bisphosphate binding nucleus cytoplasm cytoplasm cytosol cytoskeleton plasma membrane cytoskeleton organization skeletal muscle tissue development actin polymerization or depolymerization actin cytoskeleton actin cytoskeleton membrane cell junction cell projection costamere actin filament severing actin filament binding actin filament binding barbed-end actin filament capping |
|
| TC0200001757.mm.2 |
Knl1 |
kinetochore scaffold 1 |
2 |
119047118, 119047118 |
NM_029617, BC080815 NM_029617, BC080815 |
76464 |
19 |
chromosome, centromeric region kinetochore condensed chromosome kinetochore condensed chromosome kinetochore acrosomal vesicle molecular_function nucleus nucleus nucleoplasm chromosome cell cycle chromosome segregation attachment of spindle microtubules to kinetochore attachment of spindle microtubules to kinetochore negative regulation of phosphatase activity nuclear body protein localization to kinetochore protein localization to kinetochore cell division |
|
| TC1300001205.mm.2 |
Depdc1b |
DEP domain containing 1B |
13 |
108316336 |
NM_178683, BC152330, BC152331 NM_178683, BC152330, BC152331 NM_178683, BC152330, BC152331 |
218581 |
16 |
molecular_function GTPase activator activity signal transduction cell migration positive regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway intracellular signal transduction |
|
| TC0700001989.mm.2 |
Lrrc27 |
leucine rich repeat containing 27 |
7 |
139212987, 139213274 |
NM_001143755, NM_027164, BC050816 NM_001143755, NM_027164, BC050816 NM_001143755, NM_027164, BC050816 |
76612 |
11 |
molecular_function |
|
| TC1200000675.mm.2 |
Mthfd1 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase |
12 |
76255231 |
NM_138745, BC008523 NM_138745, BC008523 |
108156 |
53 |
histidine biosynthetic process nucleotide binding neutrophil homeostasis neural tube closure catalytic activity formate-tetrahydrofolate ligase activity formate-tetrahydrofolate ligase activity methenyltetrahydrofolate cyclohydrolase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity ATP binding cytoplasm mitochondrion cytosol cytosol purine nucleotide biosynthetic process methionine metabolic process one-carbon metabolic process heart development metabolic process cellular amino acid biosynthetic process serine family amino acid metabolic process serine family amino acid biosynthetic process methionine biosynthetic process 10-formyltetrahydrofolate biosynthetic process 10-formyltetrahydrofolate biosynthetic process oxidoreductase activity hydrolase activity ligase activity transsulfuration tetrahydrofolate interconversion tetrahydrofolate interconversion tetrahydrofolate interconversion somite development |
00670 01100 |
| TC1700001084.mm.2 |
Ddx11 |
DEAD/H box helicase 11 |
17 |
66123519 |
NM_001003919, BC079656 NM_001003919, BC079656 |
320209 |
19 |
nucleotide binding chromatin spindle pole fibrillar center nucleic acid binding DNA binding DNA helicase activity DNA helicase activity chromatin binding DNA replication origin binding double-stranded DNA binding single-stranded DNA binding RNA binding single-stranded RNA binding helicase activity ATP binding nucleus nucleus nucleoplasm nucleolus cytoplasm centrosome cytoskeleton nucleobase-containing compound metabolic process DNA replication DNA repair cellular response to DNA damage stimulus sister chromatid cohesion multicellular organism development DNA-dependent ATPase activity RNA-dependent ATPase activity hydrolase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides midbody replication fork processing Ctf18 RFC-like complex positive regulation of endodeoxyribonuclease activity negative regulation of protein binding DNA duplex unwinding DNA duplex unwinding establishment of sister chromatid cohesion positive regulation of chromatin binding G-quadruplex DNA unwinding triplex DNA binding positive regulation of sister chromatid cohesion metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding G-quadruplex DNA binding cellular response to hydroxyurea cellular response to cisplatin positive regulation of transcription of nucleolar large rRNA by RNA polymerase I cellular response to bleomycin nucleolar chromatin organization positive regulation of double-strand break repair |
|
| TC0200000572.mm.2 |
Pomt1 |
protein-O-mannosyltransferase 1 |
2 |
32236639 |
NM_145145, BC027325 NM_145145, BC027325 |
99011 |
25 |
mannosyltransferase activity acrosomal vesicle dolichyl-phosphate-mannose-protein mannosyltransferase activity endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane protein O-linked glycosylation membrane integral component of membrane sarcoplasmic reticulum transferase activity transferase activity, transferring glycosyl groups extracellular matrix organization protein O-linked mannosylation protein O-linked mannosylation positive regulation of protein O-linked glycosylation |
00514 |
| TC0500000307.mm.2 |
|
|
|
|
NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 NM_001289522, NM_001289523, NM_023525, BC137856, BC144972, NR_105788 |
|
|
nucleotide binding UTP binding catalytic activity aspartate carbamoyltransferase activity aspartate carbamoyltransferase activity carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity dihydroorotase activity dihydroorotase activity protein kinase activity ATP binding nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol 'de novo' pyrimidine nucleobase biosynthetic process 'de novo' pyrimidine nucleobase biosynthetic process pyrimidine nucleotide biosynthetic process UTP biosynthetic process UTP biosynthetic process cellular amino acid metabolic process glutamine metabolic process glutamine metabolic process nitrogen compound metabolic process metabolic process zinc ion binding nuclear matrix amino acid binding transferase activity carboxyl- or carbamoyltransferase activity hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides ligase activity drug metabolic process peptidyl-threonine phosphorylation citrulline biosynthetic process citrulline biosynthetic process enzyme binding response to insulin protein-containing complex response to starvation identical protein binding cell projection neuronal cell body terminal bouton protein autophosphorylation metal ion binding |
|
| TC0200002749.mm.2 |
Gm14403 |
predicted gene 14403 |
2 |
177498225 |
NR_036450, BC098094 NR_036450, BC098094 |
433520 |
5 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific regulation of transcription by RNA polymerase II |
|
| TC0700004592.mm.2 |
Tnfrsf22 |
tumor necrosis factor receptor superfamily, member 22 |
7 |
-143634807 |
NM_023680 |
79202 |
16 |
protein binding extracellular region plasma membrane external side of plasma membrane cell surface membrane integral component of membrane TRAIL-activated apoptotic signaling pathway positive regulation of apoptotic process TRAIL binding negative regulation of extrinsic apoptotic signaling pathway via death domain receptors |
|
| TC0900003128.mm.2 |
Mlh1 |
mutL homolog 1 |
9 |
-111228227 |
NM_026810, BC021815 NM_026810, BC021815 |
17350 |
174 |
nucleotide binding leptotene nuclear-transcribed mRNA poly(A) tail shortening resolution of meiotic recombination intermediates condensed chromosome condensed chromosome condensed nuclear chromosome synaptonemal complex synaptonemal complex male germ cell nucleus somatic recombination of immunoglobulin genes involved in immune response chromatin binding chromatin binding single-stranded DNA binding ATP binding nucleus nucleoplasm nucleoplasm chromosome chiasma late recombination nodule DNA repair mismatch repair mismatch repair mismatch repair mismatch repair double-strand break repair via nonhomologous end joining cellular response to DNA damage stimulus cellular response to DNA damage stimulus cell cycle male meiosis chromosome segregation homologous chromosome pairing at meiosis reciprocal meiotic recombination male meiotic nuclear division spermatogenesis intrinsic apoptotic signaling pathway in response to DNA damage response to bacterium female meiosis chromosome segregation somatic hypermutation of immunoglobulin genes somatic hypermutation of immunoglobulin genes somatic recombination of immunoglobulin gene segments ATPase activity enzyme binding mismatched DNA binding guanine/thymine mispair binding guanine/thymine mispair binding mismatch repair complex MutLalpha complex MutLalpha complex MutSalpha complex binding meiotic metaphase I plate congression meiotic chromosome segregation meiotic telomere clustering homologous chromosome segregation isotype switching negative regulation of mitotic recombination positive regulation of isotype switching to IgA isotypes positive regulation of isotype switching to IgG isotypes oogenesis meiotic spindle midzone assembly meiotic cell cycle meiotic cell cycle |
03430 05200 05210 05213 |
| TC0100003531.mm.2 |
Pcp4l1 |
Purkinje cell protein 4-like 1 |
1 |
-171173263 |
NM_025557 |
66425 |
17 |
molecular_function cellular_component biological_process |
|
| TC0700001906.mm.2 |
Tacc2 |
transforming, acidic coiled-coil containing protein 2 |
7 |
130577437, 130692617 |
NM_001004468, NM_021314, NM_206856 NM_001004468, NM_021314, NM_206856 NM_001004468, NM_021314, NM_206856 |
57752 |
33 |
microtubule cytoskeleton organization microtubule cytoskeleton organization nucleus nucleoplasm cytoplasm cytosol cytoskeleton plasma membrane mitotic spindle organization cell population proliferation cell population proliferation protein domain specific binding cerebral cortex development cerebral cortex development neurogenesis interkinetic nuclear migration astral microtubule organization regulation of microtubule-based process nuclear hormone receptor binding |
|
| TC1000002313.mm.2 |
Ado |
2-aminoethanethiol (cysteamine) dioxygenase |
10 |
-67544510 |
NM_001005419, BC057106, BC058407 NM_001005419, BC057106, BC058407 NM_001005419, BC057106, BC058407 |
211488 |
18 |
protein binding mitochondrion oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen metal ion binding cysteamine dioxygenase activity dioxygenase activity |
00430 01100 |
| TC1300000070.mm.2 |
Heatr1 |
HEAT repeat containing 1 |
13 |
12395374 |
NM_144835 |
217995 |
20 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) fibrillar center nucleolus mitochondrion snoRNA binding 90S preribosome small-subunit processome t-UTP complex positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase I positive regulation of rRNA processing |
03008 |
| TC1000000940.mm.2 |
Nopchap1 |
NOP protein chaperone 1 |
10 |
83360220 |
NM_026579, BC050904, BC094241 NM_026579, BC050904, BC094241 NM_026579, BC050904, BC094241 |
28109 |
21 |
molecular_function cellular_component biological_process |
|
| TC0100002838.mm.2 |
Dtymk |
deoxythymidylate kinase |
1 |
-93792575, -93800494 |
NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902 NM_001105667, NM_023136, BC030178, BC069902 |
21915 |
24 |
nucleotide binding nucleoside diphosphate kinase activity thymidylate kinase activity thymidylate kinase activity thymidylate kinase activity ATP binding nucleus cytoplasm mitochondrion mitochondrion mitochondrial intermembrane space mitochondrial matrix cytosol dUDP biosynthetic process dTDP biosynthetic process dTDP biosynthetic process dTDP biosynthetic process dTTP biosynthetic process dTTP biosynthetic process uridylate kinase activity nucleotide biosynthetic process kinase activity phosphorylation transferase activity cellular response to growth factor stimulus |
00240 01100 |
| TC0300000935.mm.2 |
H2bc18 |
H2B clustered histone 18 |
3 |
96269699 |
NM_175666, BC019122 NM_175666, BC019122 |
319189 |
28 |
DNA binding nucleoplasm nucleoplasm cytosol nucleosome assembly |
05322 |
| TC0500002025.mm.2 |
Dnajc2 |
DnaJ heat shock protein family (Hsp40) member C2 |
5 |
-21757276 |
NM_009584, BC052027 NM_009584, BC052027 |
22791 |
33 |
DNA binding chromatin binding protein binding nucleus nucleolus cytoplasm cytosol DNA replication chromatin organization negative regulation of cell growth Hsp70 protein binding nuclear membrane histone binding positive regulation of transcription, DNA-templated ubiquitin modification-dependent histone binding negative regulation of DNA biosynthetic process |
|
| TC0600000127.mm.2 |
Cav2 |
caveolin 2 |
6 |
17281184, 17281184 |
NM_001277756, NM_016900, BC023095 NM_001277756, NM_016900, BC023095 NM_001277756, NM_016900, BC023095 |
12390 |
68 |
SNARE binding negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation acrosomal membrane caveolar macromolecular signaling complex protein binding nucleus nuclear envelope nuclear inner membrane cytoplasm endoplasmic reticulum Golgi apparatus Golgi apparatus lipid droplet cytosol plasma membrane plasma membrane integral component of plasma membrane integral component of plasma membrane caveola caveola caveola focal adhesion focal adhesion focal adhesion endocytosis vesicle fusion vesicle fusion mitochondrion organization endoplasmic reticulum organization chemical synaptic transmission negative regulation of cell population proliferation insulin receptor signaling pathway insulin receptor signaling pathway cell surface membrane membrane vesicle organization receptor-mediated endocytosis of virus by host cell protein kinase binding protein kinase binding protein kinase binding syntaxin binding transport vesicle cell differentiation negative regulation of transforming growth factor beta receptor signaling pathway protein-macromolecule adaptor activity extrinsic component of cytoplasmic side of plasma membrane extrinsic component of cytoplasmic side of plasma membrane cytoplasmic vesicle cytoplasmic vesicle mitogen-activated protein kinase kinase kinase binding D1 dopamine receptor binding D1 dopamine receptor binding protein-containing complex protein-containing complex sarcolemma protein homodimerization activity positive regulation of MAPK cascade positive regulation of MAPK cascade positive regulation of GTPase activity positive regulation by host of viral release from host cell positive regulation by host of viral process membrane raft protein heterodimerization activity vesicle docking vesicle docking perinuclear region of cytoplasm perinuclear region of cytoplasm perinuclear region of cytoplasm skeletal muscle fiber development positive regulation of peptidyl-tyrosine phosphorylation phosphoprotein binding regulation of cytosolic calcium ion concentration molecular adaptor activity molecular adaptor activity positive regulation of dopamine receptor signaling pathway positive regulation of dopamine receptor signaling pathway caveola assembly caveola assembly caveola assembly basement membrane organization scaffold protein binding positive regulation of protein localization to nucleus |
04144 04510 05100 |
| TC1100000021.mm.2 |
Morc2a |
microrchidia 2A |
11 |
3649436, 3658671 |
NM_001159288, NM_198162, BC059243 NM_001159288, NM_198162, BC059243 NM_001159288, NM_198162, BC059243 |
74522 |
25 |
nucleotide binding magnesium ion binding heterochromatin chromatin binding protein binding ATP binding nucleus nucleus nucleoplasm chromosome cytoplasm cytosol chromatin remodeling cellular response to DNA damage stimulus zinc ion binding nuclear matrix hydrolase activity ATPase activity histone binding protein homodimerization activity negative regulation of gene expression, epigenetic negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of single stranded viral RNA replication via double stranded DNA intermediate metal ion binding positive regulation of DNA methylation-dependent heterochromatin assembly positive regulation of DNA methylation-dependent heterochromatin assembly |
|
| TC0X00001555.mm.2 |
Rragb |
Ras-related GTP binding B |
X |
153139957 |
NM_001004154, BC069180, BC070407 NM_001004154, BC069180, BC070407 NM_001004154, BC069180, BC070407 |
245670 |
11 |
nucleotide binding GTPase activity GTPase activity GTP binding nucleus cytoplasm lysosome lysosome cellular response to starvation regulation of autophagy hydrolase activity regulation of TOR signaling positive regulation of TOR signaling positive regulation of TOR signaling guanyl ribonucleotide binding cellular response to amino acid starvation EGO complex cellular protein localization GTPase binding cellular response to amino acid stimulus cellular response to amino acid stimulus positive regulation of TORC1 signaling Gtr1-Gtr2 GTPase complex cellular response to leucine starvation |
|
| TC1100000164.mm.2 |
Fbxo48 |
F-box protein 48 |
11 |
16951409, 16951374 |
NM_176982, BC125589, BC125591 NM_176982, BC125589, BC125591 NM_176982, BC125589, BC125591 |
319701 |
10 |
molecular_function SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
| MG-1-neg-10340143_st |
|
|
|
|
|
|
|
|
|
| TC1100001899.mm.2 |
Nup85 |
nucleoporin 85 |
11 |
115564443 |
NM_001002929, BC079856 NM_001002929, BC079856 |
445007 |
21 |
chromosome, centromeric region kinetochore nucleus nuclear pore nucleoplasm chromosome cytoplasm cytosol cytoskeleton plasma membrane mRNA export from nucleus protein import into nucleus chemotaxis protein transport membrane structural constituent of nuclear pore cytokine-mediated signaling pathway lamellipodium assembly nuclear pore outer ring nuclear pore outer ring CCR2 chemokine receptor binding positive regulation of transcription, DNA-templated macrophage chemotaxis mRNA transport nephron development |
03013 |
| TC0600003136.mm.2 |
Ncapd2 |
non-SMC condensin I complex, subunit D2 |
6 |
-125168006 |
NM_146171, BC026982, BC029133 NM_146171, BC026982, BC029133 NM_146171, BC026982, BC029133 |
68298 |
32 |
nuclear chromosome mitotic cell cycle condensed chromosome, centromeric region condensed chromosome condensed chromosome condensin complex condensin complex condensin complex chromatin binding nucleus nucleoplasm chromosome cytoplasm cytosol cell cycle mitotic chromosome condensation mitotic chromosome condensation meiotic chromosome condensation chromosome condensation histone binding histone binding pronucleus cell division |
|
| TC1800000908.mm.2 |
|
|
|
|
NM_175542, NR_105777 NM_175542, NR_105777 |
|
|
molecular_function cytoplasm centrosome centriole cytoskeleton cilium centriole replication multicellular organism development determination of left/right symmetry centriole-centriole cohesion integral component of membrane ciliary basal body organization ciliary basal body ciliary basal body cell projection cilium organization |
|
| TC0200002721.mm.2 |
|
|
|
|
NM_001242943, NM_001242944, XR_140546 NM_001242943, NM_001242944, XR_140546 NM_001242943, NM_001242944, XR_140546 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific cellular_component nucleoplasm regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| TC0400000622.mm.2 |
Abitram |
actin binding transcription modulator |
4 |
56802328 |
NM_001081420, BC026590, BC048548 NM_001081420, BC026590, BC048548 NM_001081420, BC026590, BC048548 |
230234 |
18 |
actin binding actin monomer binding actin monomer binding nucleus nucleus nuclear speck lamellipodium lamellipodium dendrite dendrite growth cone regulation of actin filament polymerization regulation of actin filament polymerization filopodium tip filopodium tip cell projection dendrite morphogenesis dendrite morphogenesis actin filament binding actin filament binding regulation of filopodium assembly regulation of filopodium assembly |
|
| TC0X00000652.mm.2 |
Hmgb3 |
high mobility group box 3 |
X |
71555916 |
NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037 NM_008253, BC011276, BC083352, BC158037 |
15354 |
39 |
immune system process DNA binding RNA binding nucleus chromosome cytoplasm regulation of transcription by RNA polymerase II DNA binding, bending innate immune response negative regulation of B cell differentiation negative regulation of myeloid cell differentiation |
|
| TC1000001301.mm.2 |
Phlda1 |
pleckstrin homology like domain, family A, member 1 |
10 |
111506285 |
NM_009344, BC010295 NM_009344, BC010295 |
21664 |
37 |
protein binding nucleus nucleoplasm nucleolus cytoplasm apoptotic process cytoplasmic vesicle positive regulation of apoptotic process positive regulation of apoptotic process FasL biosynthetic process |
|
| TC0400003633.mm.2 |
Nkain1 |
Na+/K+ transporting ATPase interacting 1 |
4 |
-130530130 |
NM_025998, BC116391 NM_025998, BC116391 |
67149 |
18 |
regulation of sodium ion transport plasma membrane membrane integral component of membrane ATPase binding |
|
| TC1500000392.mm.2 |
Deptor |
DEP domain containing MTOR-interacting protein |
15 |
55112316, 55133435 |
NM_001037937, NM_145470, BC156690 NM_001037937, NM_145470, BC156690 NM_001037937, NM_145470, BC156690 |
97998 |
42 |
negative regulation of protein kinase activity negative regulation of TOR signaling intracellular signal transduction negative regulation of cell size regulation of extrinsic apoptotic signaling pathway |
|
| TC1700000070.mm.2 |
Rps6ka2 |
ribosomal protein S6 kinase, polypeptide 2 |
17 |
7170114 |
NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 NM_011299, BC043064, BC051079, BC055331, BC056946 |
20112 |
56 |
nucleotide binding magnesium ion binding oocyte maturation brain renin-angiotensin system protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ribosomal protein S6 kinase activity ribosomal protein S6 kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding nucleus nucleoplasm nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm spindle protein phosphorylation heart development negative regulation of cell population proliferation positive regulation of gene expression cardiac muscle cell apoptotic process kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation intracellular signal transduction positive regulation of apoptotic process negative regulation of cell cycle negative regulation of meiotic nuclear division heart contraction regulation of protein processing regulation of protein processing cellular response to carbohydrate stimulus meiotic spindle |
04010 04114 04150 04720 04722 04914 |
| TC0900000111.mm.2 |
Mre11a |
MRE11A homolog A, double strand break repair nuclease |
9 |
14784653 |
NM_018736, BC065144 NM_018736, BC065144 |
17535 |
75 |
single-stranded DNA endodeoxyribonuclease activity single-stranded DNA endodeoxyribonuclease activity telomere maintenance double-strand break repair via homologous recombination double-strand break repair via homologous recombination chromosome, telomeric region chromosome, telomeric region chromatin condensed nuclear chromosome DNA binding DNA helicase activity nuclease activity endonuclease activity endodeoxyribonuclease activity exonuclease activity protein binding nucleus nucleus nucleoplasm replication fork chromosome cytoplasm DNA repair double-strand break repair double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining cellular response to DNA damage stimulus sister chromatid cohesion mitotic G2 DNA damage checkpoint mitotic G2 DNA damage checkpoint homologous chromosome pairing at meiosis protein C-terminus binding cell population proliferation 3'-5' exonuclease activity 5'-3' exonuclease activity PML body PML body hydrolase activity manganese ion binding Mre11 complex Mre11 complex intra-S DNA damage checkpoint intra-S DNA damage checkpoint telomeric 3' overhang formation positive regulation of protein autophosphorylation positive regulation of telomere maintenance DNA duplex unwinding positive regulation of kinase activity site of double-strand break site of double-strand break meiotic DNA double-strand break formation identical protein binding negative regulation of apoptotic process negative regulation of viral entry into host cell perinuclear region of cytoplasm chromosome organization meiotic cell cycle mitochondrial double-strand break repair via homologous recombination DNA strand resection involved in replication fork processing |
03440 03450 |
| MG-1-pos-10340853_st |
|
|
|
|
|
|
|
|
|
| TC0200001756.mm.2 |
Rpusd2 |
RNA pseudouridylate synthase domain containing 2 |
2 |
119034789 |
NM_173450, BC117827, BC117828 NM_173450, BC117827, BC117828 NM_173450, BC117827, BC117828 |
271842 |
13 |
enzyme-directed rRNA pseudouridine synthesis pseudouridine synthesis RNA binding RNA modification pseudouridine synthase activity |
|
| TC0600000344.mm.2 |
Nup205 |
nucleoporin 205 |
6 |
35177615 |
NM_027513, BC141333 NM_027513, BC141333 |
70699 |
22 |
nuclear pore nuclear pore organization structural constituent of nuclear pore structural constituent of nuclear pore nuclear membrane nuclear periphery nuclear pore inner ring nuclear pore complex assembly |
03013 |
| TC1000000158.mm.2 |
Mtfr2 |
mitochondrial fission regulator 2 |
10 |
20347818 |
NM_027930, BC019132 NM_027930, BC019132 |
71804 |
16 |
mitochondrial fission mitochondrial fission molecular_function mitochondrion mitochondrion mitochondrion organization aerobic respiration aerobic respiration |
|
| TC0300001478.mm.2 |
Znhit6 |
zinc finger, HIT type 6 |
3 |
145576215, 145576207 |
NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 NM_001081094, BC147498, BC150966, BC150967, BC151198 |
229937 |
13 |
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) box C/D snoRNP assembly box C/D snoRNP assembly TFIID-class transcription factor complex binding nucleus enzyme binding ribosome biogenesis identical protein binding metal ion binding snoRNA localization snoRNA localization ATPase binding protein complex oligomerization pre-snoRNP complex pre-snoRNP complex |
|
| TC0200005383.mm.2 |
Zfp931 |
zinc finger protein 931 |
2 |
-178066877 |
NM_001162922 |
353208 |
11 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| TC0200002719.mm.2 |
|
|
|
|
NM_001033123, NM_001199308 NM_001033123, NM_001199308 |
|
|
molecular_function cellular_component biological_process |
|
| TC0200002737.mm.2 |
|
|
|
|
NM_001033123, NM_001199307 NM_001033123, NM_001199307 |
|
|
molecular_function cellular_component biological_process |
|
| MG-1-neg-10342821_st |
|
|
|
|
|
|
|
|
|
| TC0900001442.mm.2 |
Cdc25a |
cell division cycle 25A |
9 |
109875578 |
NM_007658, BC046296 NM_007658, BC046296 |
12530 |
68 |
G1/S transition of mitotic cell cycle G2/M transition of mitotic cell cycle phosphoprotein phosphatase activity protein tyrosine phosphatase activity intracellular anatomical structure nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm protein dephosphorylation cell cycle response to radiation positive regulation of G2/M transition of mitotic cell cycle hydrolase activity protein kinase binding cellular response to UV chaperone binding cell division positive regulation of G2/MI transition of meiotic cell cycle positive regulation of cell cycle G2/M phase transition positive regulation of cholangiocyte proliferation |
04110 04914 |
| TC1000002493.mm.2 |
Gamt |
guanidinoacetate methyltransferase |
10 |
-80258150 |
NM_010255, BC049233 NM_010255, BC049233 |
14431 |
39 |
nucleus cytoplasm cytosol creatine biosynthetic process creatine biosynthetic process creatine biosynthetic process spermatogenesis methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity animal organ morphogenesis transferase activity guanidinoacetate N-methyltransferase activity guanidinoacetate N-methyltransferase activity methylation regulation of multicellular organism growth identical protein binding cell projection S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process |
00260 00330 01100 |
| MG-1-neg-10339227_st |
|
|
|
|
|
|
|
|
|
| TC0X00000897.mm.2 |
|
|
|
|
NM_001199337, NM_001199338, NM_001199339, NM_026673, NR_004438, BC016557, BC107208, BC107209 NM_001199337, NM_001199338, NM_001199339, NM_026673, NR_004438, BC016557, BC107208, BC107209 NM_001199337, NM_001199338, NM_001199339, NM_026673, NR_004438, BC016557, BC107208, BC107209 NM_001199337, NM_001199338, NM_001199339, NM_026673, NR_004438, BC016557, BC107208, BC107209 NM_001199337, NM_001199338, NM_001199339, NM_026673, NR_004438, BC016557, BC107208, BC107209 NM_001199337, NM_001199338, NM_001199339, NM_026673, NR_004438, BC016557, BC107208, BC107209 NM_001199337, NM_001199338, NM_001199339, NM_026673, NR_004438, BC016557, BC107208, BC107209 NM_001199337, NM_001199338, NM_001199339, NM_026673, NR_004438, BC016557, BC107208, BC107209 |
|
|
Golgi membrane extracellular region mitochondrion mitochondrion mitochondrial inner membrane endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus cytosol membrane integral component of membrane integral component of mitochondrial inner membrane cristae formation cristae formation MICOS complex MICOS complex |
|
| TC1200001306.mm.2 |
Ncapg2 |
non-SMC condensin II complex, subunit G2 |
12 |
116405435 |
NM_133762, BC076631 NM_133762, BC076631 |
76044 |
27 |
mitotic sister chromatid segregation condensin complex condensin complex condensin complex inner cell mass cell proliferation protein binding nucleus nucleus nucleoplasm transcription by RNA polymerase II transcription by RNA polymerase II cell cycle nuclear speck erythrocyte differentiation erythrocyte differentiation chromosome condensation methylated histone binding bHLH transcription factor binding cell division transcription regulator inhibitor activity |
|
| TC1600000176.mm.2 |
Nde1 |
nudE neurodevelopment protein 1 |
16 |
14163274 |
NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 NM_001114085, NM_001285503, NM_001285504, NM_023317, BC023267 |
67203 |
49 |
establishment of mitotic spindle orientation establishment of mitotic spindle orientation chromosome, centromeric region kinetochore kinetochore neuron migration protein binding chromosome cytoplasm centrosome centrosome centrosome microtubule organizing center spindle cytoskeleton kinesin complex microtubule microtubule nucleation microtubule nucleation cell cycle chromosome segregation mitotic centrosome separation multicellular organism development nervous system development neuroblast proliferation microtubule binding microtubule binding cell migration protein domain specific binding cerebral cortex development cerebral cortex development cell differentiation forebrain development microtubule organizing center organization spindle pole centrosome identical protein binding identical protein binding synapse vesicle transport along microtubule vesicle transport along microtubule centrosome duplication cell division establishment of chromosome localization establishment of chromosome localization centrosome localization regulation of microtubule motor activity |
|
| TC1400001533.mm.2 |
Dnajc9 |
DnaJ heat shock protein family (Hsp40) member C9 |
14 |
-20384637 |
NM_134081, BC014686, BC023787, BC027012 NM_134081, BC014686, BC023787, BC027012 NM_134081, BC014686, BC023787, BC027012 NM_134081, BC014686, BC023787, BC027012 |
108671 |
26 |
extracellular space nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol plasma membrane membrane heat shock protein binding heat shock protein binding positive regulation of ATPase activity |
|
| TC1800000063.mm.2 |
Colec12 |
collectin sub-family member 12 |
18 |
9707647 |
NM_130449, BC057936 NM_130449, BC057936 |
140792 |
19 |
scavenger receptor activity collagen trimer phagocytosis, recognition phagocytosis, recognition immune response membrane integral component of membrane low-density lipoprotein particle binding low-density lipoprotein particle binding carbohydrate binding toll-like receptor 3 signaling pathway signaling receptor activity pattern recognition receptor activity pattern recognition receptor activity defense response to bacterium metal ion binding positive regulation of cell adhesion molecule production collagen-containing extracellular matrix |
04145 |
| TC1100001139.mm.2 |
Dhrs13 |
dehydrogenase/reductase (SDR family) member 13 |
11 |
78032312 |
NM_183286, BC115881 NM_183286, BC115881 |
70451 |
15 |
extracellular region mitochondrial inner membrane oxidoreductase activity retinal metabolic process NADP-retinol dehydrogenase activity |
|
| TC1500001031.mm.2 |
Larp4 |
La ribonucleoprotein domain family, member 4 |
15 |
99972779, 99970064 |
NM_001024526, NM_001080948, NM_001284521, NM_001284522, NM_001284523 NM_001024526, NM_001080948, NM_001284521, NM_001284522, NM_001284523 NM_001024526, NM_001080948, NM_001284521, NM_001284522, NM_001284523 NM_001024526, NM_001080948, NM_001284521, NM_001284522, NM_001284523 NM_001024526, NM_001080948, NM_001284521, NM_001284522, NM_001284523 |
207214 |
26 |
nucleic acid binding RNA binding mRNA 3'-UTR binding cytoplasm cytosol polysome translation cytoskeleton organization poly(A) binding cytoplasmic stress granule posttranscriptional regulation of gene expression regulation of cell morphogenesis cytosolic small ribosomal subunit positive regulation of translation |
|
| TC0900000888.mm.2 |
Vps13c |
vacuolar protein sorting 13C |
9 |
67840350 |
NM_177184 |
320528 |
29 |
molecular_function mitochondrion mitochondrial outer membrane cytosol protein targeting to vacuole mitochondrion organization mitochondrion organization membrane extrinsic component of membrane dense core granule membrane response to insulin protein retention in Golgi apparatus negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization |
|
| TC1600001050.mm.2 |
Chaf1b |
chromatin assembly factor 1, subunit B (p60) |
16 |
93883900 |
NM_028083, BC013532 NM_028083, BC013532 |
110749 |
29 |
chromatin protein binding nucleus nucleoplasm cytoplasm DNA replication DNA repair nucleosome assembly DNA replication-dependent nucleosome assembly cellular response to DNA damage stimulus cell cycle chromatin assembly protein-containing complex CAF-1 complex CAF-1 complex |
|
| TC0900001083.mm.2 |
Irak1bp1 |
interleukin-1 receptor-associated kinase 1 binding protein 1 |
9 |
82829805 |
NM_001168240, NM_022986, BC061099 NM_001168240, NM_022986, BC061099 NM_001168240, NM_022986, BC061099 |
65099 |
20 |
protein binding nucleus cytoplasm immune response I-kappaB kinase/NF-kappaB signaling I-kappaB kinase/NF-kappaB signaling |
|
| TC1200001698.mm.2 |
Gm1818 |
predicted gene 1818 |
12 |
|
XR_001538 |
217536 |
1 |
|
|
| TC1500001202.mm.2 |
Brix1 |
BRX1, biogenesis of ribosomes |
15 |
-10474778 |
NM_026396, BC014832 NM_026396, BC014832 |
67832 |
23 |
ribosomal large subunit assembly RNA binding nucleus chromosome nucleolus nucleolus ribosome biogenesis |
|
| TC0500002754.mm.2 |
Sdad1 |
SDA1 domain containing 1 |
5 |
-92284009 |
NM_172713, BC042708 NM_172713, BC042708 |
231452 |
20 |
ribosomal large subunit export from nucleus molecular_function nucleus nucleoplasm nucleolus nucleolus protein transport actin cytoskeleton organization ribosome biogenesis ribosomal large subunit biogenesis cellular response to leukemia inhibitory factor |
|
| TC0200002315.mm.2 |
Asxl1 |
ASXL transcriptional regulator 1 |
2 |
153345829 |
NM_001039939, BC172725 NM_001039939, BC172725 |
228790 |
55 |
cell morphogenesis heart morphogenesis DNA binding chromatin binding transcription coactivator activity protein binding nucleus chromatin organization transcription, DNA-templated regulation of transcription, DNA-templated animal organ morphogenesis animal organ morphogenesis negative regulation of lipid storage hemopoiesis response to retinoic acid negative regulation of peroxisome proliferator activated receptor signaling pathway PR-DUB complex PR-DUB complex monoubiquitinated histone H2A deubiquitination regulation of kidney size retinoic acid receptor binding peroxisome proliferator activated receptor binding peroxisome proliferator activated receptor binding negative regulation of fat cell differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding positive regulation of retinoic acid receptor signaling pathway hematopoietic or lymphoid organ development thymus development bone marrow development homeostasis of number of cells bone development lung saccule development glomerular visceral epithelial cell development |
|
| TC0200002753.mm.2 |
Gm14327 |
predicted gene 14327 |
2 |
177897162 |
NR_038101 |
665205 |
9 |
molecular_function cellular_component biological_process |
|
| TC1100003505.mm.2 |
Akap1 |
A kinase (PRKA) anchor protein 1 |
11 |
-88830791, -88830791, -88830791 |
NM_001042541, NM_009648, NR_104310 NM_001042541, NM_009648, NR_104310 NM_001042541, NM_009648, NR_104310 |
11640 |
58 |
nucleic acid binding RNA binding protein binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum lipid droplet apoptotic process microtubule binding negative regulation of cardiac muscle hypertrophy regulation of protein kinase A signaling membrane integral component of membrane protein kinase binding protein phosphatase binding mitochondrial crista protein phosphatase 2B binding neuromuscular junction protein kinase A regulatory subunit binding negative regulation of protein dephosphorylation negative regulation of protein import into nucleus postsynaptic membrane beta-tubulin binding molecular adaptor activity antiviral innate immune response |
|
| TC0200005344.mm.2 |
|
|
|
|
NM_001177404, NM_001177405, NM_001177406, NM_001177407 NM_001177404, NM_001177405, NM_001177406, NM_001177407 NM_001177404, NM_001177405, NM_001177406, NM_001177407 NM_001177404, NM_001177405, NM_001177406, NM_001177407 |
|
|
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity cellular_component regulation of transcription by RNA polymerase II |
|
| TC0600001744.mm.2 |
Klhl42 |
kelch-like 42 |
6 |
147091074 |
NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 NM_001081237, BC147633, BC147636, BC151064, BC151065, BC151068, BC151076 |
232539 |
16 |
protein polyubiquitination protein polyubiquitination ubiquitin-protein transferase activity cytoplasm cytoskeleton cell cycle Cul3-RING ubiquitin ligase complex regulation of microtubule-based process regulation of microtubule-based process proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process cell division |
|
| TC0800000691.mm.2 |
Naf1 |
nuclear assembly factor 1 ribonucleoprotein |
8 |
66860216 |
NM_001163564 |
234344 |
15 |
snoRNA guided rRNA pseudouridine synthesis box H/ACA snoRNP assembly box H/ACA snoRNP assembly pseudouridine synthesis RNA binding RNA binding nucleus nucleoplasm sno(s)RNA-containing ribonucleoprotein complex sno(s)RNA-containing ribonucleoprotein complex cytoplasm rRNA processing ribosome biogenesis ribosome biogenesis identical protein binding RNA stabilization positive regulation of telomerase activity telomerase RNA binding telomerase RNA stabilization positive regulation of telomere maintenance via telomere lengthening telomerase holoenzyme complex assembly |
|
| TC1800000081.mm.2 |
Snrpd1 |
small nuclear ribonucleoprotein D1 |
18 |
10617795 |
NM_009226, BC024875 NM_009226, BC024875 |
20641 |
33 |
commitment complex spliceosomal snRNP assembly spliceosomal snRNP assembly mRNA splicing, via spliceosome RNA binding nucleus nucleus spliceosomal complex U5 snRNP U1 snRNP U1 snRNP U2 snRNP U4 snRNP U4 snRNP U12-type spliceosomal complex U12-type spliceosomal complex cytoplasm cytosol RNA processing mRNA processing RNA splicing methylosome pICln-Sm protein complex pICln-Sm protein complex SMN-Sm protein complex SMN-Sm protein complex U4/U6 x U5 tri-snRNP complex U2-type precatalytic spliceosome U2-type catalytic step 2 spliceosome precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome spliceosomal tri-snRNP complex U1 snRNP binding |
03040 05322 |
| TC1700002286.mm.2 |
Sgo1 |
shugoshin 1 |
17 |
-53674786 |
NM_028232, BC089014 NM_028232, BC089014 |
72415 |
41 |
mitotic sister chromatid segregation chromosome, centromeric region chromosome, centromeric region kinetochore kinetochore kinetochore condensed chromosome, centromeric region condensed chromosome, centromeric region spindle pole nucleus nucleoplasm chromosome cytoplasm centrosome cytosol cytoskeleton cell cycle chromosome segregation attachment of spindle microtubules to kinetochore centriole-centriole cohesion centriole-centriole cohesion kinase binding meiotic chromosome segregation homologous chromosome segregation meiotic sister chromatid cohesion cell division mitotic sister chromatid cohesion, centromeric |
04114 |
| TC0400002236.mm.2 |
Otud6b |
OTU domain containing 6B |
4 |
-14809504 |
NM_152812, BC031474, BC087552 NM_152812, BC031474, BC087552 NM_152812, BC031474, BC087552 |
72201 |
22 |
thiol-dependent ubiquitin-specific protease activity thiol-dependent ubiquitin-specific protease activity proteolysis peptidase activity cysteine-type peptidase activity cell population proliferation eukaryotic translation initiation factor 4F complex protein deubiquitination protein deubiquitination hydrolase activity negative regulation of translation proteasome assembly positive regulation of translation |
|
| TC1900001630.mm.2 |
Sh3pxd2a |
SH3 and PX domains 2A |
19 |
-47260173 |
NM_001164717, NM_008018, BC118022 NM_001164717, NM_008018, BC118022 NM_001164717, NM_008018, BC118022 |
14218 |
38 |
in utero embryonic development protease binding podosome podosome protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm cytoplasm superoxide metabolic process superoxide metabolic process phosphatidylinositol-5-phosphate binding superoxide-generating NADPH oxidase activator activity cell junction phosphatidylinositol-3-phosphate binding phosphatidylinositol binding cell projection phosphatidylinositol-3,4-bisphosphate binding molecular adaptor activity phosphatidylinositol-4-phosphate binding reactive oxygen species metabolic process osteoclast fusion |
|
| TC0X00002826.mm.2 |
Taf9b |
TATA-box binding protein associated factor 9B |
X |
-106206873, -106206873 |
NM_001001176, NM_001167988, BC066223 NM_001001176, NM_001167988, BC066223 NM_001001176, NM_001167988, BC066223 |
407786 |
20 |
negative regulation of transcription by RNA polymerase II nucleus transcription factor TFIID complex transcription factor TFIID complex DNA-templated transcription, initiation transcription by RNA polymerase II RNA polymerase II general transcription initiation factor activity positive regulation of cell growth transcription factor TFTC complex negative regulation of apoptotic process protein heterodimerization activity protein stabilization |
03022 |
| TC0600000854.mm.2 |
Retsat |
retinol saturase (all trans retinol 13,14 reductase) |
6 |
72598601 |
NM_026159, BC117751 NM_026159, BC117751 |
67442 |
29 |
nuclear outer membrane endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane membrane oxidoreductase activity nuclear membrane retinol metabolic process retinol metabolic process all-trans-retinol 13,14-reductase activity all-trans-retinol 13,14-reductase activity all-trans-retinol 13,14-reductase activity |
00830 |
| TC0200005468.mm.2 |
Nup188 |
nucleoporin 188 |
2 |
30286415 |
NM_198304, BC096591 NM_198304, BC096591 |
227699 |
25 |
nucleus nuclear pore RNA export from nucleus protein import into nucleus protein import into nucleus protein transport structural constituent of nuclear pore nuclear pore inner ring mRNA transport |
03013 |
| TC0100002413.mm.2 |
Raph1 |
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 |
1 |
-60483184 |
NM_001045513 |
77300 |
23 |
protein binding cytosol cytosol plasma membrane plasma membrane nuclear body cell leading edge axon extension |
|
| TC0100001303.mm.2 |
Aspm |
abnormal spindle microtubule assembly |
1 |
139454772 |
NM_009791 |
12316 |
49 |
spindle pole neuron migration neuron migration positive regulation of neuroblast proliferation positive regulation of neuroblast proliferation calmodulin binding nucleus cytoplasm centrosome cytoskeleton microtubule cell cycle spindle organization spermatogenesis brain development male gonad development apical plasma membrane forebrain neuroblast division cerebral cortex development midbody midbody microtubule minus-end negative regulation of neuron differentiation negative regulation of asymmetric cell division oogenesis developmental growth cell division regulation of meiotic cell cycle spindle localization maintenance of centrosome location meiotic spindle positive regulation of canonical Wnt signaling pathway spindle assembly involved in meiosis neuronal stem cell population maintenance mitotic spindle pole mitotic spindle pole |
|
| TC1100002592.mm.2 |
Lsm11 |
U7 snRNP-specific Sm-like protein LSM11 |
11 |
-45928268 |
NM_028185, BC094286, U7-specific-like NM_028185, BC094286, U7-specific-like NM_028185, BC094286, U7-specific-like |
72290 |
19 |
RNA binding protein binding nucleus nucleoplasm U7 snRNP U7 snRNP U7 snRNP telomerase holoenzyme complex mRNA processing mRNA 3'-end processing by stem-loop binding and cleavage mRNA 3'-end processing by stem-loop binding and cleavage nuclear body histone pre-mRNA 3'end processing complex U7 snRNA binding U7 snRNA binding positive regulation of G1/S transition of mitotic cell cycle |
|
| TC0800001977.mm.2 |
Mak16 |
MAK16 homolog |
8 |
-31159467 |
NM_026453, BC013079 NM_026453, BC013079 |
67920 |
23 |
maturation of 5.8S rRNA maturation of LSU-rRNA nucleus nucleolus nucleolus preribosome, large subunit precursor intracellular membrane-bounded organelle |
|
| TC0500001152.mm.2 |
Chek2 |
checkpoint kinase 2 |
5 |
110839982, 110839982 |
NM_016681, BC056617 NM_016681, BC056617 |
50883 |
109 |
DNA damage checkpoint mitotic G2 phase G2/M transition of mitotic cell cycle nucleotide binding chromosome, telomeric region positive regulation of protein phosphorylation protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm Golgi apparatus DNA repair double-strand break repair regulation of transcription, DNA-templated protein phosphorylation apoptotic process cellular response to DNA damage stimulus DNA damage induced protein phosphorylation DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle intrinsic apoptotic signaling pathway in response to DNA damage response to gamma radiation kinase activity phosphorylation PML body transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation protein kinase binding ubiquitin protein ligase binding regulation of protein catabolic process signal transduction in response to DNA damage signal transduction in response to DNA damage signal transduction in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding protein homodimerization activity cellular protein catabolic process mitotic DNA damage checkpoint positive regulation of transcription, DNA-templated protein autophosphorylation metal ion binding protein stabilization cell division negative regulation of cell cycle arrest cellular response to gamma radiation signal transduction involved in intra-S DNA damage checkpoint mitotic spindle assembly negative regulation of DNA damage checkpoint positive regulation of anoikis |
04110 04115 |
| TC0900001568.mm.2 |
Ctdspl |
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
9 |
118926535 |
NM_133710, BC094289 NM_133710, BC094289 |
69274 |
17 |
negative regulation of protein phosphorylation phosphoprotein phosphatase activity nucleus regulation of transcription by RNA polymerase II RNA polymerase II CTD heptapeptide repeat phosphatase activity hydrolase activity phosphatase activity metal ion binding negative regulation of G1/S transition of mitotic cell cycle |
|
| TC0200005346.mm.2 |
|
|
|
|
XR_140554 |
|
|
|
|
| TC0200005491.mm.2 |
|
|
|
|
XM_003688779 |
|
|
|
|
| MG-1-neg-10343148_st |
|
|
|
|
|
|
|
|
|
| TC0200002755.mm.2 |
Zfp971 |
zinc finger protein 971 |
2 |
178023283, 178023283 |
NM_001177399, NM_001177400 NM_001177399, NM_001177400 |
626848 |
10 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific regulation of transcription by RNA polymerase II |
|
| TC0800000172.mm.2 |
Agpat5 |
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) |
8 |
18846278 |
NM_026792, BC031987 NM_026792, BC031987 |
52123 |
28 |
hematopoietic progenitor cell differentiation 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity nucleus nuclear envelope mitochondrion mitochondrion mitochondrion endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process acylglycerol metabolic process phospholipid biosynthetic process endomembrane system membrane integral component of membrane transferase activity transferase activity, transferring acyl groups |
|
| TC0700000732.mm.2 |
|
|
|
|
XR_030795 |
|
|
|
|
| TC1700001197.mm.2 |
Rmdn2 |
regulator of microtubule dynamics 2 |
17 |
79626674, 79615216, 79615216, 79614899 |
NM_201361, BC024059 NM_201361, BC024059 |
381110 |
16 |
cytoplasm cytoplasm mitochondrion mitochondrion Golgi apparatus cytosol cytoskeleton microtubule spindle microtubule spindle microtubule microtubule binding microtubule binding biological_process membrane integral component of membrane mitotic spindle mitotic spindle pole mitotic spindle pole |
|
| TC0X00001658.mm.2 |
Ap1s2 |
adaptor-related protein complex 1, sigma 2 subunit |
X |
163909016, 163909016 |
NM_026887, BC046964 NM_026887, BC046964 |
108012 |
28 |
protein binding Golgi apparatus clathrin-coated pit intracellular protein transport visual learning protein transport membrane synaptic vesicle budding from endosome synaptic vesicle budding from endosome vesicle-mediated transport vesicle-mediated transport membrane coat cytoplasmic vesicle synaptic vesicle recycling intracellular membrane-bounded organelle intracellular membrane-bounded organelle fat cell differentiation neuromuscular process controlling balance adipose tissue development |
04142 |
| TC0200001352.mm.2 |
Nup160 |
nucleoporin 160 |
2 |
90677214 |
NM_021512, BC052450, BC054523 NM_021512, BC052450, BC054523 NM_021512, BC052450, BC054523 |
59015 |
28 |
kinetochore nucleus nuclear pore nuclear pore nuclear pore mRNA export from nucleus mRNA export from nucleus protein transport structural constituent of nuclear pore structural constituent of nuclear pore structural constituent of nuclear pore nuclear pore outer ring mRNA transport nephron development |
03013 |
| TC1300000571.mm.2 |
Nol8 |
nucleolar protein 8 |
13 |
49653077 |
NM_001271397, NR_073167, NR_073168, BC125575, BC125579, NM_001081350 NM_001271397, NR_073167, NR_073168, BC125575, BC125579, NM_001081350 NM_001271397, NR_073167, NR_073168, BC125575, BC125579, NM_001081350 NM_001271397, NR_073167, NR_073168, BC125575, BC125579, NM_001081350 NM_001271397, NR_073167, NR_073168, BC125575, BC125579, NM_001081350 NM_001271397, NR_073167, NR_073168, BC125575, BC125579, NM_001081350 |
70930 |
22 |
nucleic acid binding RNA binding nucleus chromosome nucleolus nucleolus rRNA processing protein localization to nucleolus protein localization to nucleolus cellular response to leukemia inhibitory factor |
|
| TC0X00002631.mm.2 |
Pola1 |
polymerase (DNA directed), alpha 1 |
X |
-93304765 |
NM_008892, BC138047 NM_008892, BC138047 |
18968 |
36 |
nucleotide binding DNA synthesis involved in DNA repair chromatin nucleoside binding nucleic acid binding DNA binding chromatin binding chromatin binding DNA replication origin binding double-stranded DNA binding single-stranded DNA binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity protein binding nucleus nucleus nuclear envelope nucleoplasm alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex alpha DNA polymerase:primase complex nucleolus cytoplasm cytosol DNA replication DNA replication DNA replication DNA replication, synthesis of RNA primer DNA replication, synthesis of RNA primer DNA replication initiation DNA strand elongation involved in DNA replication leading strand elongation leading strand elongation lagging strand elongation lagging strand elongation double-strand break repair via nonhomologous end joining nuclear matrix transferase activity nucleotidyltransferase activity purine nucleotide binding purine nucleotide binding pyrimidine nucleotide binding pyrimidine nucleotide binding protein kinase binding regulation of type I interferon production metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding DNA biosynthetic process mitotic DNA replication initiation |
00230 00240 01100 03030 |
| TC0200004250.mm.2 |
Qser1 |
glutamine and serine rich 1 |
2 |
-104754792 |
NM_001123327 |
99003 |
19 |
molecular_function cellular_component biological_process |
|
| TC1400002290.mm.2 |
Cdca2 |
cell division cycle associated 2 |
14 |
-67676353, -67676353 |
NM_001110162, NM_175384, BC116298, BC116299 NM_001110162, NM_175384, BC116298, BC116299 NM_001110162, NM_175384, BC116298, BC116299 NM_001110162, NM_175384, BC116298, BC116299 |
108912 |
22 |
molecular_function nucleus nucleoplasm chromosome cytosol cell cycle chromosome segregation positive regulation of protein dephosphorylation cell division |
|
| TC0100001494.mm.2 |
Mettl18 |
methyltransferase like 18 |
1 |
163994888 |
NM_027279, BC050143, BC052693 NM_027279, BC050143, BC052693 NM_027279, BC050143, BC052693 |
69962 |
15 |
methyltransferase activity transferase activity protein-histidine N-methyltransferase activity heat shock protein binding methylation protein-containing complex peptidyl-histidine methylation, to form tele-methylhistidine |
|